Early adversity and depressive symptoms among early adolescent girls: the mediating role of exposure to recent interpersonal acute stress / Catherine B. STROUD in Development and Psychopathology, 35-3 (August 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-3 (August 2023) . - p.1272-1287 Titre : Early adversity and depressive symptoms among early adolescent girls: the mediating role of exposure to recent interpersonal acute stress Type de document : Texte imprimé et/ou numérique Auteurs : Catherine B. STROUD, Auteur ; Frances R. CHEN, Auteur ; Erin E. DUNNING, Auteur ; Julia CHENG, Auteur ; Carey MARR, Auteur ; Suzanne VRSHEK-SCHALLHORN, Auteur Article en page(s) : p.1272-1287 Langues : Anglais (eng) Mots-clés : adolescents  depression  early adversity  interpersonal stress  stressful life events Index. décimale : PER Périodiques Résumé : Early adversity confers risk for depression in part through its association with recent (i.e., proximal) acute stress. However, it remains unresolved whether: a) early adversity predicts increases in recent acute stress over time; b) all - or only certain types - of recent events mediate the relationship between early adversity and depression; and c) early adversity places individuals at greater risk for depression via greater exposure to independent (i.e., fateful) interpersonal events or via greater generation of dependent (i.e., partially self-initiated) interpersonal events (i.e., stress generation) or both. These questions were examined in a 3-wave longitudinal study of early adolescent girls (N = 125; M = 12.35 years [SD = .77]) with no history of diagnosable depression using contextual life stress and diagnostic interviews. Path analyses indicated that increases in past-year acute interpersonal, but not non-interpersonal, stress mediated the link between early adversity and depressive symptoms. The mediating role of interpersonal events was limited to independent ones, suggesting increases in interpersonal event exposure, not interpersonal stress generation, acted as a mediator. Finally, findings support prior evidence that early adversity may not directly predict future depressive symptoms. Implications for understanding the role of recent stress in the association between early adversity and adolescent depression are discussed. En ligne : http://dx.doi.org/10.1017/S0954579421001176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511 [article] Early adversity and depressive symptoms among early adolescent girls: the mediating role of exposure to recent interpersonal acute stress [Texte imprimé et/ou numérique] / Catherine B. STROUD, Auteur ; Frances R. CHEN, Auteur ; Erin E. DUNNING, Auteur ; Julia CHENG, Auteur ; Carey MARR, Auteur ; Suzanne VRSHEK-SCHALLHORN, Auteur . - p.1272-1287. Langues : Anglais (eng) in Development and Psychopathology > 35-3 (August 2023) . - p.1272-1287 Mots-clés : adolescents  depression  early adversity  interpersonal stress  stressful life events Index. décimale : PER Périodiques Résumé : Early adversity confers risk for depression in part through its association with recent (i.e., proximal) acute stress. However, it remains unresolved whether: a) early adversity predicts increases in recent acute stress over time; b) all - or only certain types - of recent events mediate the relationship between early adversity and depression; and c) early adversity places individuals at greater risk for depression via greater exposure to independent (i.e., fateful) interpersonal events or via greater generation of dependent (i.e., partially self-initiated) interpersonal events (i.e., stress generation) or both. These questions were examined in a 3-wave longitudinal study of early adolescent girls (N = 125; M = 12.35 years [SD = .77]) with no history of diagnosable depression using contextual life stress and diagnostic interviews. Path analyses indicated that increases in past-year acute interpersonal, but not non-interpersonal, stress mediated the link between early adversity and depressive symptoms. The mediating role of interpersonal events was limited to independent ones, suggesting increases in interpersonal event exposure, not interpersonal stress generation, acted as a mediator. Finally, findings support prior evidence that early adversity may not directly predict future depressive symptoms. Implications for understanding the role of recent stress in the association between early adversity and adolescent depression are discussed. En ligne : http://dx.doi.org/10.1017/S0954579421001176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511

Experiences of adversity in childhood and adolescence and cortisol in late adolescence / Courtenay L. KESSLER in Development and Psychopathology, 35-3 (August 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-3 (August 2023) . - p.1235-1250 Titre : Experiences of adversity in childhood and adolescence and cortisol in late adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Courtenay L. KESSLER, Auteur ; Suzanne VRSHEK-SCHALLHORN, Auteur ; Susan MINEKA, Auteur ; Richard E. ZINBARG, Auteur ; Michelle CRASKE, Auteur ; Emma K. ADAM, Auteur Article en page(s) : p.1235-1250 Langues : Anglais (eng) Mots-clés : cortisol  diurnal rhythm  early adversity  HPA axis Index. décimale : PER Périodiques Résumé : Early life adversity influences the diurnal cortisol rhythm, yet the relative influence of different characteristics of adversity remains unknown. In this study, we examine how developmental timing (childhood vs. adolescence), severity (major vs. minor), and domain of early life adversity relate to diurnal cortisol rhythms in late adolescence. We assessed adversity retrospectively in early adulthood in a subsample of 236 participants from a longitudinal study of a diverse community sample of suburban adolescents oversampled for high neuroticism. We used multilevel modeling to assess associations between our adversity measures and the diurnal cortisol rhythm (waking and bedtime cortisol, awakening response, slope, and average cortisol). Major childhood adversities were associated with flatter daily slope, and minor adolescent adversities were associated with greater average daily cortisol. Examining domains of childhood adversities, major neglect and sexual abuse were associated with flatter slope and lower waking cortisol, with sexual abuse also associated with higher cortisol awakening response. Major physical abuse was associated with higher waking cortisol. Among adolescent adversities domains, minor neglect, emotional abuse, and witnessing violence were associated with greater average cortisol. These results suggest severity, developmental timing, and domain of adversity influence the association of early life adversity with stress response system functioning. En ligne : http://dx.doi.org/10.1017/S0954579421001152 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Experiences of adversity in childhood and adolescence and cortisol in late adolescence [Texte imprimé et/ou numérique] / Courtenay L. KESSLER, Auteur ; Suzanne VRSHEK-SCHALLHORN, Auteur ; Susan MINEKA, Auteur ; Richard E. ZINBARG, Auteur ; Michelle CRASKE, Auteur ; Emma K. ADAM, Auteur . - p.1235-1250. Langues : Anglais (eng) in Development and Psychopathology > 35-3 (August 2023) . - p.1235-1250 Mots-clés : cortisol  diurnal rhythm  early adversity  HPA axis Index. décimale : PER Périodiques Résumé : Early life adversity influences the diurnal cortisol rhythm, yet the relative influence of different characteristics of adversity remains unknown. In this study, we examine how developmental timing (childhood vs. adolescence), severity (major vs. minor), and domain of early life adversity relate to diurnal cortisol rhythms in late adolescence. We assessed adversity retrospectively in early adulthood in a subsample of 236 participants from a longitudinal study of a diverse community sample of suburban adolescents oversampled for high neuroticism. We used multilevel modeling to assess associations between our adversity measures and the diurnal cortisol rhythm (waking and bedtime cortisol, awakening response, slope, and average cortisol). Major childhood adversities were associated with flatter daily slope, and minor adolescent adversities were associated with greater average daily cortisol. Examining domains of childhood adversities, major neglect and sexual abuse were associated with flatter slope and lower waking cortisol, with sexual abuse also associated with higher cortisol awakening response. Major physical abuse was associated with higher waking cortisol. Among adolescent adversities domains, minor neglect, emotional abuse, and witnessing violence were associated with greater average cortisol. These results suggest severity, developmental timing, and domain of adversity influence the association of early life adversity with stress response system functioning. En ligne : http://dx.doi.org/10.1017/S0954579421001152 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Stress sensitization to depression following childhood adversity: Moderation by HPA axis and serotonergic multilocus profile scores / Lisa R. STARR in Development and Psychopathology, 33-4 (October 2021)  

Public ISBD [article]  inDevelopment and Psychopathology > 33-4 (October 2021) . - p.1264-1278 Titre : Stress sensitization to depression following childhood adversity: Moderation by HPA axis and serotonergic multilocus profile scores Type de document : Texte imprimé et/ou numérique Auteurs : Lisa R. STARR, Auteur ; Catherine B. STROUD, Auteur ; Zoey A. SHAW, Auteur ; Suzanne VRSHEK-SCHALLHORN, Auteur Article en page(s) : p.1264-1278 Langues : Anglais (eng) Mots-clés : childhood adversity  depression  gene-by-environment interaction  genetic  stress sensitization  stressful life events Index. décimale : PER Périodiques Résumé : Childhood adversity appears to sensitize youth to stress, increasing depression risk following stressful life events occurring throughout the lifespan. Some evidence suggests hypothalamic–pituitary–adrenal (HPA) axis-related and serotonergic genetic variation moderates this effect, in a “gene-by-environment-by-environment” interaction (G × E × E). However, prior research has tested single genetic variants, limiting power. The current study uses a multilocus genetic profile score (MGPS) approach to capture polygenic risk relevant to HPA axis and serotonergic functioning. Adolescents (N = 241, Mage = 15.90) completed contextual-threat-based interviews assessing childhood adversity and acute life events, and diagnostic interviews assessing depression. Established MGPSs indexed genetic variation linked to HPA axis (10 single nucleotide polymorphisms [SNPs]) and serotonergic (five SNPs) functioning. Results showed significant MGPS × Childhood Adversity × Recent Life Stress interactions predicting depression for both HPA axis and serotonergic MGPSs, with both risk scores predicting stronger Childhood Adversity × Recent Stress interactions. Serotonergic genetic risk specifically predicted sensitization to major interpersonal stressors. The serotonergic MGPS G × E × E was re-tested in an independent replication sample of early adolescent girls, with comparable results. Findings support the notion that genetic variation linked to these two neurobiological symptoms alters stress sensitization, and that gene-by-environment (G × E) interactions may be qualified by environmental exposures occurring at different points in development. En ligne : http://dx.doi.org/10.1017/S0954579420000474 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 [article] Stress sensitization to depression following childhood adversity: Moderation by HPA axis and serotonergic multilocus profile scores [Texte imprimé et/ou numérique] / Lisa R. STARR, Auteur ; Catherine B. STROUD, Auteur ; Zoey A. SHAW, Auteur ; Suzanne VRSHEK-SCHALLHORN, Auteur . - p.1264-1278. Langues : Anglais (eng) in Development and Psychopathology > 33-4 (October 2021) . - p.1264-1278 Mots-clés : childhood adversity  depression  gene-by-environment interaction  genetic  stress sensitization  stressful life events Index. décimale : PER Périodiques Résumé : Childhood adversity appears to sensitize youth to stress, increasing depression risk following stressful life events occurring throughout the lifespan. Some evidence suggests hypothalamic–pituitary–adrenal (HPA) axis-related and serotonergic genetic variation moderates this effect, in a “gene-by-environment-by-environment” interaction (G × E × E). However, prior research has tested single genetic variants, limiting power. The current study uses a multilocus genetic profile score (MGPS) approach to capture polygenic risk relevant to HPA axis and serotonergic functioning. Adolescents (N = 241, Mage = 15.90) completed contextual-threat-based interviews assessing childhood adversity and acute life events, and diagnostic interviews assessing depression. Established MGPSs indexed genetic variation linked to HPA axis (10 single nucleotide polymorphisms [SNPs]) and serotonergic (five SNPs) functioning. Results showed significant MGPS × Childhood Adversity × Recent Life Stress interactions predicting depression for both HPA axis and serotonergic MGPSs, with both risk scores predicting stronger Childhood Adversity × Recent Stress interactions. Serotonergic genetic risk specifically predicted sensitization to major interpersonal stressors. The serotonergic MGPS G × E × E was re-tested in an independent replication sample of early adolescent girls, with comparable results. Findings support the notion that genetic variation linked to these two neurobiological symptoms alters stress sensitization, and that gene-by-environment (G × E) interactions may be qualified by environmental exposures occurring at different points in development. En ligne : http://dx.doi.org/10.1017/S0954579420000474 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457

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