Brief Report: Health-Related Quality of Life in Preschoolers with Autism Spectrum Disorder is Related to Diagnostic Age and Autistic Symptom Severity / Mauricio A. LOPEZ-ESPEJO in Journal of Autism and Developmental Disorders, 51-12 (December 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-12 (December 2021) . - p.4704-4710 Titre : Brief Report: Health-Related Quality of Life in Preschoolers with Autism Spectrum Disorder is Related to Diagnostic Age and Autistic Symptom Severity Type de document : texte imprimé Auteurs : Mauricio A. LOPEZ-ESPEJO, Auteur ; Alicia C. NUÑEZ, Auteur ; Odalie C. MOSCOSO, Auteur ; Raul G. ESCOBAR, Auteur Article en page(s) : p.4704-4710 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis  Autistic Disorder  Caregivers  Child, Preschool  Cross-Sectional Studies  Humans  Quality of Life  Autism spectrum disorder  Preschool children  Regression analysis Index. décimale : PER Périodiques Résumé : We conducted a cross-sectional study to explore whether clinical characteristics and autism diagnostic-traits severity are associated with caregiver-reported impairment of health-related quality of life (Pediatric Quality of Life Inventory Generic Core Scales, Fourth Edition) in 93 Chilean toddlers (age: 2-4 years) with autism spectrum disorder. Median total scale, physical health, and psychosocial health scores were 76 (IQR 70-81), 88 (IQR 81-94), and 71 (IQR 62-79), respectively. In multiple-regression analysis, diagnostic age (β = 0.219; p 0.021) and Calibrated Severity Score of Autism Diagnostic Observation Schedule, second edition (β = - 0.434; p < 0.001) were independently correlated to the total scale score. Lower age and higher autistic traits severity at diagnosis are correlated with worse well-being perception by caregivers. En ligne : http://dx.doi.org/10.1007/s10803-021-04909-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454 [article] Brief Report: Health-Related Quality of Life in Preschoolers with Autism Spectrum Disorder is Related to Diagnostic Age and Autistic Symptom Severity [texte imprimé] / Mauricio A. LOPEZ-ESPEJO, Auteur ; Alicia C. NUÑEZ, Auteur ; Odalie C. MOSCOSO, Auteur ; Raul G. ESCOBAR, Auteur . - p.4704-4710. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-12 (December 2021) . - p.4704-4710 Mots-clés : Autism Spectrum Disorder/diagnosis  Autistic Disorder  Caregivers  Child, Preschool  Cross-Sectional Studies  Humans  Quality of Life  Autism spectrum disorder  Preschool children  Regression analysis Index. décimale : PER Périodiques Résumé : We conducted a cross-sectional study to explore whether clinical characteristics and autism diagnostic-traits severity are associated with caregiver-reported impairment of health-related quality of life (Pediatric Quality of Life Inventory Generic Core Scales, Fourth Edition) in 93 Chilean toddlers (age: 2-4 years) with autism spectrum disorder. Median total scale, physical health, and psychosocial health scores were 76 (IQR 70-81), 88 (IQR 81-94), and 71 (IQR 62-79), respectively. In multiple-regression analysis, diagnostic age (β = 0.219; p 0.021) and Calibrated Severity Score of Autism Diagnostic Observation Schedule, second edition (β = - 0.434; p < 0.001) were independently correlated to the total scale score. Lower age and higher autistic traits severity at diagnosis are correlated with worse well-being perception by caregivers. En ligne : http://dx.doi.org/10.1007/s10803-021-04909-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454

Caregiver-Child Agreement in Health-Related Quality of Life of Autistic Children and Adolescents / Mauricio A. LOPEZ-ESPEJO in Journal of Autism and Developmental Disorders, 53-3 (March 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-3 (March 2023) . - p.977-986 Titre : Caregiver-Child Agreement in Health-Related Quality of Life of Autistic Children and Adolescents Type de document : texte imprimé Auteurs : Mauricio A. LOPEZ-ESPEJO, Auteur ; Alicia C. NUÑEZ, Auteur ; Melanie RUZ, Auteur ; Valentina SAEZ, Auteur ; Odalie C. MOSCOSO, Auteur ; Raul G. ESCOBAR, Auteur Article en page(s) : p.977-986 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : This study examined the agreement of perceived health-related quality of life (HRQOL) between caregivers and autistic children and adolescents (n=133, 5-12 years) using the Pediatric Quality of Life Inventory Generic Core Scales, Fourth Edition (PedsQL 4.0). Results reveal good to excellent agreement over this age range across the total, physical, and psychosocial health scales. However, the emotional, social, and school functioning scores demonstrated lower agreement in dyads with children aged 5-7 than in dyads with children aged 8-12 years. Despite these differences in agreement, overall, the PedsQL 4.0 caregiver-module is a reliable instrument for measuring HRQOL in autistic individuals aged 5-12 years. En ligne : https://doi.org/10.1007/s10803-022-05689-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=500 [article] Caregiver-Child Agreement in Health-Related Quality of Life of Autistic Children and Adolescents [texte imprimé] / Mauricio A. LOPEZ-ESPEJO, Auteur ; Alicia C. NUÑEZ, Auteur ; Melanie RUZ, Auteur ; Valentina SAEZ, Auteur ; Odalie C. MOSCOSO, Auteur ; Raul G. ESCOBAR, Auteur . - p.977-986. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-3 (March 2023) . - p.977-986 Index. décimale : PER Périodiques Résumé : This study examined the agreement of perceived health-related quality of life (HRQOL) between caregivers and autistic children and adolescents (n=133, 5-12 years) using the Pediatric Quality of Life Inventory Generic Core Scales, Fourth Edition (PedsQL 4.0). Results reveal good to excellent agreement over this age range across the total, physical, and psychosocial health scales. However, the emotional, social, and school functioning scores demonstrated lower agreement in dyads with children aged 5-7 than in dyads with children aged 8-12 years. Despite these differences in agreement, overall, the PedsQL 4.0 caregiver-module is a reliable instrument for measuring HRQOL in autistic individuals aged 5-12 years. En ligne : https://doi.org/10.1007/s10803-022-05689-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=500

The Influence of Social and Developmental Factors on the Timing of Autism Spectrum Disorder Diagnosis of Preschool-Aged Children: Evidence from a Specialized Chilean Center / Alicia C. NUÑEZ ; Valentina SAEZ ; Melanie RUZ ; Odalie C. MOSCOSO ; Alejandra VIVES in Journal of Autism and Developmental Disorders, 55-8 (August 2025)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 55-8 (August 2025) . - p.2797-2806 Titre : The Influence of Social and Developmental Factors on the Timing of Autism Spectrum Disorder Diagnosis of Preschool-Aged Children: Evidence from a Specialized Chilean Center Type de document : texte imprimé Auteurs : Alicia C. NUÑEZ, Auteur ; Valentina SAEZ, Auteur ; Melanie RUZ, Auteur ; Odalie C. MOSCOSO, Auteur ; Alejandra VIVES, Auteur Article en page(s) : p.2797-2806 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : We investigated the influence of developmental and social factors on the age of autism diagnosis (AoD) in a cohort of toddlers living in Chile. A cross-sectional study was conducted among 509 preschool children diagnosed with autism spectrum disorder [M = 40.2 months (SD = 8.6), girls: 32%] in the neurodevelopmental unit of a university clinic in Santiago, Chile (2015-2023). Structural changes in the annual trend of AoD were tested. Generalized linear models (gamma distribution) with and without interaction terms were used for the multivariate analysis, adjusting for gender, residential area, year of diagnosis, developmental variables (language regression, delayed walking, and use of expressive verbal language), and primary caregiver age and education level (CEL). 95% confidence intervals of the unstandardized regression coefficients (B) were calculated using 1000 bootstrap resampling to estimate associations. AoD increased between 2021-2022 and decreased in 2023. Female gender (B = 2.72 [1.21-4.23]), no history of language regression (B = 3.97 [1.66-6.28]), and the presence of expressive verbal language at diagnosis (B = 1.57 [0.05-3.08]) were associated with higher AoD. Children whose caregivers had tertiary education were diagnosed earlier than those with?? 12 years of formal education. Although the influence of CEL increased with caregiver age, differences between CEL groups were significant only for caregivers aged?? 30 years. Improved education and early screening for clinical features of autism among healthcare professionals and the community, with a focus on young children without highly apparent developmental concerns and those from vulnerable social groups, are warranted. En ligne : https://doi.org/10.1007/s10803-024-06376-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565 [article] The Influence of Social and Developmental Factors on the Timing of Autism Spectrum Disorder Diagnosis of Preschool-Aged Children: Evidence from a Specialized Chilean Center [texte imprimé] / Alicia C. NUÑEZ, Auteur ; Valentina SAEZ, Auteur ; Melanie RUZ, Auteur ; Odalie C. MOSCOSO, Auteur ; Alejandra VIVES, Auteur . - p.2797-2806. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 55-8 (August 2025) . - p.2797-2806 Index. décimale : PER Périodiques Résumé : We investigated the influence of developmental and social factors on the age of autism diagnosis (AoD) in a cohort of toddlers living in Chile. A cross-sectional study was conducted among 509 preschool children diagnosed with autism spectrum disorder [M = 40.2 months (SD = 8.6), girls: 32%] in the neurodevelopmental unit of a university clinic in Santiago, Chile (2015-2023). Structural changes in the annual trend of AoD were tested. Generalized linear models (gamma distribution) with and without interaction terms were used for the multivariate analysis, adjusting for gender, residential area, year of diagnosis, developmental variables (language regression, delayed walking, and use of expressive verbal language), and primary caregiver age and education level (CEL). 95% confidence intervals of the unstandardized regression coefficients (B) were calculated using 1000 bootstrap resampling to estimate associations. AoD increased between 2021-2022 and decreased in 2023. Female gender (B = 2.72 [1.21-4.23]), no history of language regression (B = 3.97 [1.66-6.28]), and the presence of expressive verbal language at diagnosis (B = 1.57 [0.05-3.08]) were associated with higher AoD. Children whose caregivers had tertiary education were diagnosed earlier than those with?? 12 years of formal education. Although the influence of CEL increased with caregiver age, differences between CEL groups were significant only for caregivers aged?? 30 years. Improved education and early screening for clinical features of autism among healthcare professionals and the community, with a focus on young children without highly apparent developmental concerns and those from vulnerable social groups, are warranted. En ligne : https://doi.org/10.1007/s10803-024-06376-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565

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