Amygdala responses to threat in violence-exposed children depend on trauma context and maternal caregiving / Jennifer S. STEVENS in Development and Psychopathology, 35-3 (August 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-3 (August 2023) . - p.1159-1170 Titre : Amygdala responses to threat in violence-exposed children depend on trauma context and maternal caregiving Type de document : texte imprimé Auteurs : Jennifer S. STEVENS, Auteur ; Sanne J. H. VAN ROOIJ, Auteur ; Anais F. STENSON, Auteur ; Timothy D. ELY, Auteur ; Abigail POWERS, Auteur ; Aimee CLIFFORD, Auteur ; Ye Ji KIM, Auteur ; Rebecca HINRICHS, Auteur ; Nim TOTTENHAM, Auteur ; Tanja JOVANOVIC, Auteur Article en page(s) : p.1159-1170 Langues : Anglais (eng) Mots-clés : amygdala  habituation  maternal buffering  resilience  violence exposure Index. décimale : PER Périodiques Résumé : Early life adversity (ELA) has been linked with increased arousal responses to threat, including increased amygdala reactivity. Effects of ELA on brain function are well recognized, and emerging evidence suggests that caregivers may influence how environmental stressors impact children s brain function. We investigated the hypothesis that positive interaction between mother and child can buffer against ELA effects on children s neural responses to threat, and related symptoms. N = 53 mother-child pairs (children ages 8-14 years) were recruited from an urban population at high risk for violence exposure. Maternal caregiving was measured using the Parenting Questionnaire and in a cooperation challenge task. Children viewed fearful and neutral face stimuli during functional magnetic resonance imaging. Children who experienced greater violence at home showed amygdala sensitization, whereas children experiencing more school and community violence showed amygdala habituation. Sensitization was in turn linked with externalizing symptoms. However, maternal warmth was associated with a normalization of amygdala sensitization in children, and fewer externalizing behaviors prospectively up to 1 year later. Findings suggested that the effects of violence exposure on threat-related neural circuitry depend on trauma context (inside or outside the home) and that primary caregivers can increase resilience. En ligne : http://dx.doi.org/10.1017/S0954579421001085 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Amygdala responses to threat in violence-exposed children depend on trauma context and maternal caregiving [texte imprimé] / Jennifer S. STEVENS, Auteur ; Sanne J. H. VAN ROOIJ, Auteur ; Anais F. STENSON, Auteur ; Timothy D. ELY, Auteur ; Abigail POWERS, Auteur ; Aimee CLIFFORD, Auteur ; Ye Ji KIM, Auteur ; Rebecca HINRICHS, Auteur ; Nim TOTTENHAM, Auteur ; Tanja JOVANOVIC, Auteur . - p.1159-1170. Langues : Anglais (eng) in Development and Psychopathology > 35-3 (August 2023) . - p.1159-1170 Mots-clés : amygdala  habituation  maternal buffering  resilience  violence exposure Index. décimale : PER Périodiques Résumé : Early life adversity (ELA) has been linked with increased arousal responses to threat, including increased amygdala reactivity. Effects of ELA on brain function are well recognized, and emerging evidence suggests that caregivers may influence how environmental stressors impact children s brain function. We investigated the hypothesis that positive interaction between mother and child can buffer against ELA effects on children s neural responses to threat, and related symptoms. N = 53 mother-child pairs (children ages 8-14 years) were recruited from an urban population at high risk for violence exposure. Maternal caregiving was measured using the Parenting Questionnaire and in a cooperation challenge task. Children viewed fearful and neutral face stimuli during functional magnetic resonance imaging. Children who experienced greater violence at home showed amygdala sensitization, whereas children experiencing more school and community violence showed amygdala habituation. Sensitization was in turn linked with externalizing symptoms. However, maternal warmth was associated with a normalization of amygdala sensitization in children, and fewer externalizing behaviors prospectively up to 1 year later. Findings suggested that the effects of violence exposure on threat-related neural circuitry depend on trauma context (inside or outside the home) and that primary caregivers can increase resilience. En ligne : http://dx.doi.org/10.1017/S0954579421001085 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Impacts of early life adversity on the neurocircuitry of emotional memory in children / Anais STENSON ; Sanne J. H. VAN ROOIJ ; Colin B. JOHNSON ; Timothy D. ELY ; Abigail POWERS ; Sean T. MINTON ; Charis WILTSHIRE ; Ye Ji KIM ; Rebecca HINRICHS ; Tanja JOVANOVIC ; Jennifer S. STEVENS in Development and Psychopathology, 37-4 (October 2025)  

Public ISBD [article]  inDevelopment and Psychopathology > 37-4 (October 2025) . - p.2126-2137 Titre : Impacts of early life adversity on the neurocircuitry of emotional memory in children Type de document : texte imprimé Auteurs : Anais STENSON, Auteur ; Sanne J. H. VAN ROOIJ, Auteur ; Colin B. JOHNSON, Auteur ; Timothy D. ELY, Auteur ; Abigail POWERS, Auteur ; Sean T. MINTON, Auteur ; Charis WILTSHIRE, Auteur ; Ye Ji KIM, Auteur ; Rebecca HINRICHS, Auteur ; Tanja JOVANOVIC, Auteur ; Jennifer S. STEVENS, Auteur Article en page(s) : p.2126-2137 Langues : Anglais (eng) Mots-clés : Childhood trauma  Emotional episodic memory  early life adversity  fMRI  ventral visual cortex Index. décimale : PER Périodiques Résumé : Similar to adults with posttraumatic stress disorder, children with early life adversity show bias in memory for negative emotional stimuli. However, it is not well understood how childhood adversity impacts mechanisms underlying emotional memory. N = 56 children (8-14 years, 48% female) reported on adverse experiences including potentially traumatic events and underwent fMRI while attending to emotionally pleasant, neutral, or negative images. Post-scan, participants completed a cued recall test to assess memory for these images. Emotional difference-in-memory (DM) scores were computed by subtracting negative or positive from neutral recall performance. All children showed enhancing effects of emotion on recall, with no effect of trauma load. However, children with less trauma showed a larger emotional DM for both positive and negative stimuli when amygdala or anterior hippocampal activity was higher. In contrast, highly trauma-exposed children demonstrated a lower emotional DM with greater amygdala or hippocampal activity. This suggested that alternative neural mechanisms might support emotional enhancement of encoding in children with greater trauma load. Whole-brain analyses revealed that right fusiform activity during encoding positively correlated with both trauma load and successful later recall of positive images. Therefore, highly trauma-exposed children may use alternative, potentially adaptive neural pathways via the ventral visual stream to encode positive emotional events. En ligne : https://dx.doi.org/10.1017/S0954579424001718 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=567 [article] Impacts of early life adversity on the neurocircuitry of emotional memory in children [texte imprimé] / Anais STENSON, Auteur ; Sanne J. H. VAN ROOIJ, Auteur ; Colin B. JOHNSON, Auteur ; Timothy D. ELY, Auteur ; Abigail POWERS, Auteur ; Sean T. MINTON, Auteur ; Charis WILTSHIRE, Auteur ; Ye Ji KIM, Auteur ; Rebecca HINRICHS, Auteur ; Tanja JOVANOVIC, Auteur ; Jennifer S. STEVENS, Auteur . - p.2126-2137. Langues : Anglais (eng) in Development and Psychopathology > 37-4 (October 2025) . - p.2126-2137 Mots-clés : Childhood trauma  Emotional episodic memory  early life adversity  fMRI  ventral visual cortex Index. décimale : PER Périodiques Résumé : Similar to adults with posttraumatic stress disorder, children with early life adversity show bias in memory for negative emotional stimuli. However, it is not well understood how childhood adversity impacts mechanisms underlying emotional memory. N = 56 children (8-14 years, 48% female) reported on adverse experiences including potentially traumatic events and underwent fMRI while attending to emotionally pleasant, neutral, or negative images. Post-scan, participants completed a cued recall test to assess memory for these images. Emotional difference-in-memory (DM) scores were computed by subtracting negative or positive from neutral recall performance. All children showed enhancing effects of emotion on recall, with no effect of trauma load. However, children with less trauma showed a larger emotional DM for both positive and negative stimuli when amygdala or anterior hippocampal activity was higher. In contrast, highly trauma-exposed children demonstrated a lower emotional DM with greater amygdala or hippocampal activity. This suggested that alternative neural mechanisms might support emotional enhancement of encoding in children with greater trauma load. Whole-brain analyses revealed that right fusiform activity during encoding positively correlated with both trauma load and successful later recall of positive images. Therefore, highly trauma-exposed children may use alternative, potentially adaptive neural pathways via the ventral visual stream to encode positive emotional events. En ligne : https://dx.doi.org/10.1017/S0954579424001718 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=567

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