Association between depression diagnosis and educational attainment trajectories: an historical cohort study using linked data / Alice WICKERSHAM in Journal of Child Psychology and Psychiatry, 64-11 (November 2023)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 64-11 (November 2023) . - p.1617-1627 Titre : Association between depression diagnosis and educational attainment trajectories: an historical cohort study using linked data Type de document : texte imprimé Auteurs : Alice WICKERSHAM, Auteur ; Ben CARTER, Auteur ; Amelia JEWELL, Auteur ; Tamsin FORD, Auteur ; Robert STEWART, Auteur ; Johnny DOWNS, Auteur Article en page(s) : p.1617-1627 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Depression symptoms are thought to be associated with lower educational attainment, but patterns of change in attainment among those who receive a clinical diagnosis of depression at any point during childhood and adolescence remain unclear. Methods We conducted a secondary analysis of an existing data linkage between a national educational dataset (National Pupil Database) and pseudonymised electronic health records (Clinical Record Interactive Search) from a large mental healthcare provider in London, United Kingdom (2007 to 2013). A cohort of 222,027 pupils were included. We used Growth Mixture Modelling (GMM) and stakeholder input to estimate trajectories of standardised educational attainment over School Years 2, 6 and 11. Multinomial logistic regression analyses were then used to investigate the association between resulting educational attainment trajectory membership (outcome) and depression diagnosis any time before age 18 (exposure). Results A five-trajectory GMM solution for attainment was derived: (1) average/high-stable, (2) average-modest declining, (3) average-steep declining, (4) low-improving and (5) low-stable. After adjusting for clinical and sociodemographic covariates, having a depression diagnosis before age 18 was associated with occupying the average-modest declining trajectory (RRR = 2.80, 95% CI 2.36-3.32, p<.001) or the average-steep declining trajectory (RRR = 3.54, 95% CI 3.10-4.04, p<.001), as compared to the average/high-stable trajectory. Conclusions Receiving a diagnosis of depression before age 18 was associated with a relative decline in attainment throughout school. While these findings cannot support a causal direction, they nonetheless suggest a need for timely mental health and educational support among pupils struggling with depression. En ligne : https://doi.org/10.1111/jcpp.13759 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512 [article] Association between depression diagnosis and educational attainment trajectories: an historical cohort study using linked data [texte imprimé] / Alice WICKERSHAM, Auteur ; Ben CARTER, Auteur ; Amelia JEWELL, Auteur ; Tamsin FORD, Auteur ; Robert STEWART, Auteur ; Johnny DOWNS, Auteur . - p.1617-1627. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 64-11 (November 2023) . - p.1617-1627 Index. décimale : PER Périodiques Résumé : Background Depression symptoms are thought to be associated with lower educational attainment, but patterns of change in attainment among those who receive a clinical diagnosis of depression at any point during childhood and adolescence remain unclear. Methods We conducted a secondary analysis of an existing data linkage between a national educational dataset (National Pupil Database) and pseudonymised electronic health records (Clinical Record Interactive Search) from a large mental healthcare provider in London, United Kingdom (2007 to 2013). A cohort of 222,027 pupils were included. We used Growth Mixture Modelling (GMM) and stakeholder input to estimate trajectories of standardised educational attainment over School Years 2, 6 and 11. Multinomial logistic regression analyses were then used to investigate the association between resulting educational attainment trajectory membership (outcome) and depression diagnosis any time before age 18 (exposure). Results A five-trajectory GMM solution for attainment was derived: (1) average/high-stable, (2) average-modest declining, (3) average-steep declining, (4) low-improving and (5) low-stable. After adjusting for clinical and sociodemographic covariates, having a depression diagnosis before age 18 was associated with occupying the average-modest declining trajectory (RRR = 2.80, 95% CI 2.36-3.32, p<.001) or the average-steep declining trajectory (RRR = 3.54, 95% CI 3.10-4.04, p<.001), as compared to the average/high-stable trajectory. Conclusions Receiving a diagnosis of depression before age 18 was associated with a relative decline in attainment throughout school. While these findings cannot support a causal direction, they nonetheless suggest a need for timely mental health and educational support among pupils struggling with depression. En ligne : https://doi.org/10.1111/jcpp.13759 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512

Maternal expressions of warmth and negativity and adolescent mental health: using longitudinal monozygotic twin-difference analyses to approach causal inference / Alice WICKERSHAM in Journal of Child Psychology and Psychiatry, 67-1 (January 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-1 (January 2026) . - p.92-103 Titre : Maternal expressions of warmth and negativity and adolescent mental health: using longitudinal monozygotic twin-difference analyses to approach causal inference Type de document : texte imprimé Auteurs : Alice WICKERSHAM, Auteur ; Avshalom CASPI, Auteur ; Louise ARSENEAULT, Auteur ; Terrie E. MOFFITT, Auteur ; Johnny DOWNS, Auteur ; Antony AMBLER, Auteur ; Rachel M. LATHAM, Auteur ; Nicholas CUMMINS, Auteur ; Zoë FIRTH, Auteur ; Jasmin WERTZ, Auteur ; Helen L. FISHER, Auteur Article en page(s) : p.92-103 Langues : Anglais (eng) Mots-clés : Expressed emotion  mental health  adolescence  cohort study  parenting  twins Index. décimale : PER Périodiques Résumé : Background Emotions that mothers express about their offspring are associated with offspring mental health during childhood, but little research has explored whether this extends into adolescence. We investigated associations between maternal warmth and negativity towards twin offspring at age 10, and subsequent mental health outcomes in early and late adolescence. Methods The Environmental Risk (E-Risk) Longitudinal Twin Study is a population-based cohort of 2,232 same-sex twins born in 1994?1995 across England and Wales. Maternal warmth and negativity were assessed from Five-Minute Speech Samples obtained when twins were aged 10. Continuous mental health outcomes were assessed in interviews with twins at ages 12 (depression, anxiety, attention-deficit hyperactivity disorder and conduct disorder) and 18 (general psychopathology, internalising, externalising and thought disorder). Linear regressions were conducted on 1906 participants with available data and adjusted for sex, family socioeconomic status, and age-5 emotional and behavioural problems. We then conducted a monozygotic twin-difference analysis to control for unmeasured shared environmental and genetic factors. Results Lower maternal warmth and higher maternal negativity were associated with worse mental health outcomes at ages 12 and 18. For example, when comparing differences in mothers' expressed emotions and mental health outcomes within monozygotic twin pairs, higher negativity remained associated with externalising symptoms (b?=?1.77, 95% CI?=?0.68 to 2.86, ??=?.14) and poorer general psychopathology (b?=?1.82, 95% CI?=?0.63 to 3.01, ??=?.13), and lower warmth with externalising symptoms (b?=??1.96, 95% CI?=??3.54 to ?0.37, ??=??.11). These associations remained after adjusting for twin-differences in age-5 emotional and behavioural problems and birth weight. Null findings were more frequently observed for maternal warmth and internalising outcomes. Conclusions Using a genetically sensitive design to approach causal inference, we found evidence for associations between maternal warmth/negativity and adolescent mental health outcomes. Maternal expressed emotion ratings might provide an early opportunity to identify families who would benefit from interventions and mental health disorder prevention programmes. En ligne : https://doi.org/10.1111/jcpp.70020 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=578 [article] Maternal expressions of warmth and negativity and adolescent mental health: using longitudinal monozygotic twin-difference analyses to approach causal inference [texte imprimé] / Alice WICKERSHAM, Auteur ; Avshalom CASPI, Auteur ; Louise ARSENEAULT, Auteur ; Terrie E. MOFFITT, Auteur ; Johnny DOWNS, Auteur ; Antony AMBLER, Auteur ; Rachel M. LATHAM, Auteur ; Nicholas CUMMINS, Auteur ; Zoë FIRTH, Auteur ; Jasmin WERTZ, Auteur ; Helen L. FISHER, Auteur . - p.92-103. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-1 (January 2026) . - p.92-103 Mots-clés : Expressed emotion  mental health  adolescence  cohort study  parenting  twins Index. décimale : PER Périodiques Résumé : Background Emotions that mothers express about their offspring are associated with offspring mental health during childhood, but little research has explored whether this extends into adolescence. We investigated associations between maternal warmth and negativity towards twin offspring at age 10, and subsequent mental health outcomes in early and late adolescence. Methods The Environmental Risk (E-Risk) Longitudinal Twin Study is a population-based cohort of 2,232 same-sex twins born in 1994?1995 across England and Wales. Maternal warmth and negativity were assessed from Five-Minute Speech Samples obtained when twins were aged 10. Continuous mental health outcomes were assessed in interviews with twins at ages 12 (depression, anxiety, attention-deficit hyperactivity disorder and conduct disorder) and 18 (general psychopathology, internalising, externalising and thought disorder). Linear regressions were conducted on 1906 participants with available data and adjusted for sex, family socioeconomic status, and age-5 emotional and behavioural problems. We then conducted a monozygotic twin-difference analysis to control for unmeasured shared environmental and genetic factors. Results Lower maternal warmth and higher maternal negativity were associated with worse mental health outcomes at ages 12 and 18. For example, when comparing differences in mothers' expressed emotions and mental health outcomes within monozygotic twin pairs, higher negativity remained associated with externalising symptoms (b?=?1.77, 95% CI?=?0.68 to 2.86, ??=?.14) and poorer general psychopathology (b?=?1.82, 95% CI?=?0.63 to 3.01, ??=?.13), and lower warmth with externalising symptoms (b?=??1.96, 95% CI?=??3.54 to ?0.37, ??=??.11). These associations remained after adjusting for twin-differences in age-5 emotional and behavioural problems and birth weight. Null findings were more frequently observed for maternal warmth and internalising outcomes. Conclusions Using a genetically sensitive design to approach causal inference, we found evidence for associations between maternal warmth/negativity and adolescent mental health outcomes. Maternal expressed emotion ratings might provide an early opportunity to identify families who would benefit from interventions and mental health disorder prevention programmes. En ligne : https://doi.org/10.1111/jcpp.70020 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=578

Research Review: The impact of the COVID-19 pandemic on the mental health of children and young people with pre-existing mental health and neurodevelopmental conditions - a systematic review and meta-analysis of longitudinal studies / Brian C.F. CHING in Journal of Child Psychology and Psychiatry, 66-8 (August 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1274-1298 Titre : Research Review: The impact of the COVID-19 pandemic on the mental health of children and young people with pre-existing mental health and neurodevelopmental conditions - a systematic review and meta-analysis of longitudinal studies Type de document : texte imprimé Auteurs : Brian C.F. CHING, Auteur ; Johnny DOWNS, Auteur ; Shuo ZHANG, Auteur ; Hannah ABDUL CADER, Auteur ; Jessica PENHALLOW, Auteur ; Elvina VORAITE, Auteur ; Teodora POPNIKOLOVA, Auteur ; Alice WICKERSHAM, Auteur ; Valeria PARLATINI, Auteur ; Emily SIMONOFF, Auteur Article en page(s) : p.1274-1298 Langues : Anglais (eng) Mots-clés : COVID-19  pandemic  children and young people  longitudinal  mental health  neurodevelopmental Index. décimale : PER Périodiques Résumé : Background Systematic reviews have suggested mixed effects of the COVID-19 pandemic on the mental health of children and young people. However, most included studies focused on the general population and were cross-sectional. The long-term impact on those with pre-existing mental health and/or neurodevelopmental conditions remains unclear. Thus, we conducted a systematic review and meta-analysis to examine the longitudinal impact of the pandemic on the mental health of this clinical population and potential explanatory factors. Methods Ovid Medline, Embase, APA PsycInfo and Global Health databases were searched between 1 January 2020 and 3 August 2023 (PROSPERO CRD42022383546). We included longitudinal studies that compared mental health symptoms between pre- and during pandemic and/or during pandemic timepoints in children and young people ( 18 years old) with pre-existing mental and/or neurodevelopmental conditions. Outcomes included internalising, externalising and other symptoms. Risk of bias was rated using an adapted tool. Included studies were narratively synthesised and multi-level meta-analyses were conducted where the number of studies was sufficient. Results We identified 21 studies (N 2,617) from 6,083 records. Studies differed across countries, diagnoses, measures, informants and timepoints. All had overall moderate-to-high risk of bias. Narrative synthesis found mixed evidence of symptom change, with individual studies showing increase/reduction/no change. Factors such as diagnosis, baseline symptom severity, age and sex/gender may explain variation in outcomes. Multi-level meta-analyses were feasible for a limited number of outcomes and found no significant changes in internalising and externalising symptoms pre- versus during pandemic or internalising symptoms between 2020 pandemic phases, and high heterogeneity was noted. Conclusions The impact of the pandemic on the mental health of children and young people with pre-existing conditions varied according to individual and contextual vulnerabilities, which were not fully captured in pooled analyses. Further research needs to investigate longer-term impacts and better stratify this vulnerable population. En ligne : https://doi.org/10.1111/jcpp.14117 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565 [article] Research Review: The impact of the COVID-19 pandemic on the mental health of children and young people with pre-existing mental health and neurodevelopmental conditions - a systematic review and meta-analysis of longitudinal studies [texte imprimé] / Brian C.F. CHING, Auteur ; Johnny DOWNS, Auteur ; Shuo ZHANG, Auteur ; Hannah ABDUL CADER, Auteur ; Jessica PENHALLOW, Auteur ; Elvina VORAITE, Auteur ; Teodora POPNIKOLOVA, Auteur ; Alice WICKERSHAM, Auteur ; Valeria PARLATINI, Auteur ; Emily SIMONOFF, Auteur . - p.1274-1298. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1274-1298 Mots-clés : COVID-19  pandemic  children and young people  longitudinal  mental health  neurodevelopmental Index. décimale : PER Périodiques Résumé : Background Systematic reviews have suggested mixed effects of the COVID-19 pandemic on the mental health of children and young people. However, most included studies focused on the general population and were cross-sectional. The long-term impact on those with pre-existing mental health and/or neurodevelopmental conditions remains unclear. Thus, we conducted a systematic review and meta-analysis to examine the longitudinal impact of the pandemic on the mental health of this clinical population and potential explanatory factors. Methods Ovid Medline, Embase, APA PsycInfo and Global Health databases were searched between 1 January 2020 and 3 August 2023 (PROSPERO CRD42022383546). We included longitudinal studies that compared mental health symptoms between pre- and during pandemic and/or during pandemic timepoints in children and young people ( 18 years old) with pre-existing mental and/or neurodevelopmental conditions. Outcomes included internalising, externalising and other symptoms. Risk of bias was rated using an adapted tool. Included studies were narratively synthesised and multi-level meta-analyses were conducted where the number of studies was sufficient. Results We identified 21 studies (N 2,617) from 6,083 records. Studies differed across countries, diagnoses, measures, informants and timepoints. All had overall moderate-to-high risk of bias. Narrative synthesis found mixed evidence of symptom change, with individual studies showing increase/reduction/no change. Factors such as diagnosis, baseline symptom severity, age and sex/gender may explain variation in outcomes. Multi-level meta-analyses were feasible for a limited number of outcomes and found no significant changes in internalising and externalising symptoms pre- versus during pandemic or internalising symptoms between 2020 pandemic phases, and high heterogeneity was noted. Conclusions The impact of the pandemic on the mental health of children and young people with pre-existing conditions varied according to individual and contextual vulnerabilities, which were not fully captured in pooled analyses. Further research needs to investigate longer-term impacts and better stratify this vulnerable population. En ligne : https://doi.org/10.1111/jcpp.14117 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565

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