13 recherche sur le mot-clé 'neurodevelopmental'

Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years After Initial Diagnosis / I. Carina GILLBERG in Journal of Autism and Developmental Disorders, 46-1 (January 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.74-82 Titre : Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years After Initial Diagnosis Type de document : Texte imprimé et/ou numérique Auteurs : I. Carina GILLBERG, Auteur ; Adam HELLES, Auteur ; Eva BILLSTEDT, Auteur ; Christopher GILLBERG, Auteur Année de publication : 2016 Article en page(s) : p.74-82 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Asperger syndrome  Psychiatric disorder  Depression  ADHD  DCD  Schizophrenia  Neurodevelopmental  Long-term follow-up Index. décimale : PER Périodiques Résumé : We examined comorbid psychiatric and neurodevelopmental disorders in fifty adult males (mean age 30 years) with Asperger syndrome (AS) diagnosed in childhood and followed up prospectively for almost two decades (13–26 years). Only three of the 50 men had never met criteria for an additional psychiatric/neurodevelopmental diagnosis and more than half had ongoing comorbidity (most commonly either ADHD or depression or both). Any psychiatric comorbidity increased the risk of poorer outcome. The minority of the AS group who no longer met criteria for a full diagnosis of an autism spectrum disorder were usually free of current psychiatric comorbidity. The high rate of psychiatric/neurodevelopmental comorbidities underscores the need for a full psychiatric/neurodevelopmental assessment at follow-up of males with AS. En ligne : http://dx.doi.org/10.1007/s10803-015-2544-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years After Initial Diagnosis [Texte imprimé et/ou numérique] / I. Carina GILLBERG, Auteur ; Adam HELLES, Auteur ; Eva BILLSTEDT, Auteur ; Christopher GILLBERG, Auteur . - 2016 . - p.74-82. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.74-82 Mots-clés : Autism spectrum disorder  Asperger syndrome  Psychiatric disorder  Depression  ADHD  DCD  Schizophrenia  Neurodevelopmental  Long-term follow-up Index. décimale : PER Périodiques Résumé : We examined comorbid psychiatric and neurodevelopmental disorders in fifty adult males (mean age 30 years) with Asperger syndrome (AS) diagnosed in childhood and followed up prospectively for almost two decades (13–26 years). Only three of the 50 men had never met criteria for an additional psychiatric/neurodevelopmental diagnosis and more than half had ongoing comorbidity (most commonly either ADHD or depression or both). Any psychiatric comorbidity increased the risk of poorer outcome. The minority of the AS group who no longer met criteria for a full diagnosis of an autism spectrum disorder were usually free of current psychiatric comorbidity. The high rate of psychiatric/neurodevelopmental comorbidities underscores the need for a full psychiatric/neurodevelopmental assessment at follow-up of males with AS. En ligne : http://dx.doi.org/10.1007/s10803-015-2544-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability / O. EYRE in Journal of Child Psychology and Psychiatry, 60-8 (August 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-8 (August 2019) . - p.866-874 Titre : Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability Type de document : Texte imprimé et/ou numérique Auteurs : O. EYRE, Auteur ; R. A. HUGHES, Auteur ; Ajay K. THAPAR, Auteur ; E. LEIBENLUFT, Auteur ; A. STRINGARIS, Auteur ; George DAVEY SMITH, Auteur ; E. STERGIAKOULI, Auteur ; S. COLLISHAW, Auteur ; A. THAPAR, Auteur Article en page(s) : p.866-874 Langues : Anglais (eng) Mots-clés : Alspac  attention-deficit/hyperactivity disorder  autism  depression  irritability  neurodevelopmental Index. décimale : PER Périodiques Résumé : BACKGROUND: Children with neurodevelopmental disorders are at increased risk of developing depression. Irritability predicts depression in the general population and is common in children with neurodevelopmental disorders. Thus, it is possible that irritability in children with neurodevelopmental disorders contributes to the link with later depression. This study aimed to (a) examine the association between childhood neurodevelopmental difficulties and adolescent depression and (b) test whether irritability explains this association. METHODS: Children with any neurodevelopmental difficulty at the age of 7-9 (n = 1,697) and a selected, comparison group without any neurodevelopmental difficulty (n = 3,177) were identified from a prospective, UK population-based cohort, the Avon Longitudinal Study of Parents and Children. Neurodevelopmental difficulties were defined as a score in the bottom 5% of the sample on at least one measure of cognitive ability, communication, autism spectrum symptoms, attention-deficit/hyperactivity symptoms, reading or motor coordination. The Development and Well-Being Assessment measured parent-reported child irritability at the age of 7, parent-reported adolescent depression at the age of 10 and 13, and self-reported depression at the age of 15. Depression measures were combined, deriving an outcome of major depressive disorder (MDD) in adolescence. Logistic regression examined the association between childhood neurodevelopmental difficulties and adolescent MDD, controlling for gender. Path analysis estimated the proportion of this association explained by irritability. Analyses were repeated for individual neurodevelopmental problems. RESULTS: Childhood neurodevelopmental difficulties were associated with adolescent MDD (OR = 2.11, 95% CI = 1.24, 3.60, p = .006). Childhood irritability statistically accounted for 42% of this association. On examining each neurodevelopmental difficulty separately, autistic, communication and ADHD problems were each associated with depression, with irritability explaining 29%-51% of these links. CONCLUSIONS: Childhood irritability appears to be a key contributor to the link between childhood neurodevelopmental difficulties and adolescent MDD. High rates of irritability in children with autistic and ADHD difficulties may explain elevated rates of depression in the neurodevelopmental group. En ligne : http://dx.doi.org/10.1111/jcpp.13053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=404 [article] Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability [Texte imprimé et/ou numérique] / O. EYRE, Auteur ; R. A. HUGHES, Auteur ; Ajay K. THAPAR, Auteur ; E. LEIBENLUFT, Auteur ; A. STRINGARIS, Auteur ; George DAVEY SMITH, Auteur ; E. STERGIAKOULI, Auteur ; S. COLLISHAW, Auteur ; A. THAPAR, Auteur . - p.866-874. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-8 (August 2019) . - p.866-874 Mots-clés : Alspac  attention-deficit/hyperactivity disorder  autism  depression  irritability  neurodevelopmental Index. décimale : PER Périodiques Résumé : BACKGROUND: Children with neurodevelopmental disorders are at increased risk of developing depression. Irritability predicts depression in the general population and is common in children with neurodevelopmental disorders. Thus, it is possible that irritability in children with neurodevelopmental disorders contributes to the link with later depression. This study aimed to (a) examine the association between childhood neurodevelopmental difficulties and adolescent depression and (b) test whether irritability explains this association. METHODS: Children with any neurodevelopmental difficulty at the age of 7-9 (n = 1,697) and a selected, comparison group without any neurodevelopmental difficulty (n = 3,177) were identified from a prospective, UK population-based cohort, the Avon Longitudinal Study of Parents and Children. Neurodevelopmental difficulties were defined as a score in the bottom 5% of the sample on at least one measure of cognitive ability, communication, autism spectrum symptoms, attention-deficit/hyperactivity symptoms, reading or motor coordination. The Development and Well-Being Assessment measured parent-reported child irritability at the age of 7, parent-reported adolescent depression at the age of 10 and 13, and self-reported depression at the age of 15. Depression measures were combined, deriving an outcome of major depressive disorder (MDD) in adolescence. Logistic regression examined the association between childhood neurodevelopmental difficulties and adolescent MDD, controlling for gender. Path analysis estimated the proportion of this association explained by irritability. Analyses were repeated for individual neurodevelopmental problems. RESULTS: Childhood neurodevelopmental difficulties were associated with adolescent MDD (OR = 2.11, 95% CI = 1.24, 3.60, p = .006). Childhood irritability statistically accounted for 42% of this association. On examining each neurodevelopmental difficulty separately, autistic, communication and ADHD problems were each associated with depression, with irritability explaining 29%-51% of these links. CONCLUSIONS: Childhood irritability appears to be a key contributor to the link between childhood neurodevelopmental difficulties and adolescent MDD. High rates of irritability in children with autistic and ADHD difficulties may explain elevated rates of depression in the neurodevelopmental group. En ligne : http://dx.doi.org/10.1111/jcpp.13053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=404

Waiting Times and Influencing Factors in Children and Adults Undergoing Assessment for Autism, ADHD, and Other Neurodevelopmental Differences / Anusua Singh ROY ; Lorna JOHNSTON ; Marie BOILSON ; Eleanor CURNOW ; Victoria JOHNSTONE-COOKE ; Marion RUTHERFORD in Autism Research, 18-4 (April 2025)  

Public ISBD [article]  inAutism Research > 18-4 (April 2025) . - p.788-801 Titre : Waiting Times and Influencing Factors in Children and Adults Undergoing Assessment for Autism, ADHD, and Other Neurodevelopmental Differences Type de document : Texte imprimé et/ou numérique Auteurs : Anusua Singh ROY, Auteur ; Lorna JOHNSTON, Auteur ; Marie BOILSON, Auteur ; Eleanor CURNOW, Auteur ; Victoria JOHNSTONE-COOKE, Auteur ; Marion RUTHERFORD, Auteur Article en page(s) : p.788-801 Langues : Anglais (eng) Mots-clés : assessment  autism  diagnosis  neurodevelopmental  pathway Index. décimale : PER Périodiques Résumé : ABSTRACT This study explored waiting times and the factors influencing them in child and adult populations undergoing assessment for autism, ADHD, and other neurodevelopmental differences. The analysis focused on a retrospective review of 408 cases with assessments completed between October 2021 and May 2022, conducted by 30 diagnosing teams in Scotland. Data included age, final diagnosis, demographics, medical and developmental history, contact frequency, and assessment service adherence to best-practice standards. Waiting times were calculated, and relationships were analyzed using linear regression. Median waiting times were 525?days (IQR 329?857) for children/adolescents and 252?days (IQR 106?611) for adults. Only 20% of children's and 47% of adult assessments met the proposed 252-day diagnostic time target. Autism and ADHD were the most common diagnoses. Receiving >?1 neurodevelopmental diagnosis on completion was uncommon. Demographic factors did not significantly affect waiting times. Children/adolescents with more complex developmental and medical histories experienced longer waits (100.3?weeks vs. 67.7?weeks; p? En ligne : https://doi.org/10.1002/aur.70011 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=554 [article] Waiting Times and Influencing Factors in Children and Adults Undergoing Assessment for Autism, ADHD, and Other Neurodevelopmental Differences [Texte imprimé et/ou numérique] / Anusua Singh ROY, Auteur ; Lorna JOHNSTON, Auteur ; Marie BOILSON, Auteur ; Eleanor CURNOW, Auteur ; Victoria JOHNSTONE-COOKE, Auteur ; Marion RUTHERFORD, Auteur . - p.788-801. Langues : Anglais (eng) in Autism Research > 18-4 (April 2025) . - p.788-801 Mots-clés : assessment  autism  diagnosis  neurodevelopmental  pathway Index. décimale : PER Périodiques Résumé : ABSTRACT This study explored waiting times and the factors influencing them in child and adult populations undergoing assessment for autism, ADHD, and other neurodevelopmental differences. The analysis focused on a retrospective review of 408 cases with assessments completed between October 2021 and May 2022, conducted by 30 diagnosing teams in Scotland. Data included age, final diagnosis, demographics, medical and developmental history, contact frequency, and assessment service adherence to best-practice standards. Waiting times were calculated, and relationships were analyzed using linear regression. Median waiting times were 525?days (IQR 329?857) for children/adolescents and 252?days (IQR 106?611) for adults. Only 20% of children's and 47% of adult assessments met the proposed 252-day diagnostic time target. Autism and ADHD were the most common diagnoses. Receiving >?1 neurodevelopmental diagnosis on completion was uncommon. Demographic factors did not significantly affect waiting times. Children/adolescents with more complex developmental and medical histories experienced longer waits (100.3?weeks vs. 67.7?weeks; p? En ligne : https://doi.org/10.1002/aur.70011 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=554

Psychometric evaluation of the revised child and family quality of life questionnaire (CFQL-2) / Thomas W. FRAZIER in Research in Autism Spectrum Disorders, 70 (February 2020)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 70 (February 2020) . - p.101474 Titre : Psychometric evaluation of the revised child and family quality of life questionnaire (CFQL-2) Type de document : Texte imprimé et/ou numérique Auteurs : Thomas W. FRAZIER, Auteur ; Allison C. HYLAND, Auteur ; Leslie A. MARKOWITZ, Auteur ; Leslie L. SPEER, Auteur ; Elizabeth A. DIEKROGER, Auteur Article en page(s) : p.101474 Langues : Anglais (eng) Mots-clés : Autism  Quality of life  Neurodevelopmental  Sensitivity to change  Behavior problems Index. décimale : PER Périodiques Résumé : Background The revised Child and Family Quality of Life (CFQL-2) questionnaire was adapted from the original version to be shorter and more sensitive to changes in psychosocial quality of life (QoL) in families of children with Autism Spectrum Disorder (ASD) or related neurodevelopmental conditions. The present study examined the psychometric properties of the CFQL-2. Methods Caregivers of 566 patients presenting to an ASD-specific diagnostic clinic completed the CFQL-2 and other behavioral measurements as part of a diagnostic evaluation. Psychometric properties, including factor structure, internal consistency reliability, reliability across the latent trait, relationships with other clinical measures, and ASD vs. non-ASD group differences were examined for the total score and each subscale. Test-retest reliability and sensitivity to change were evaluated in a separate sleep intervention trial. Results Results indicated that the CFQL-2 reliably measured eight independent QoL domains (Child, Family, Caregiver, Financial, Social Network, Partner Relationship, Coping, and QoL Change), with good-to-excellent reliability across score ranges, good test-retest reliability, and expected relationships with other measures. The change subscale was slightly, but not significantly, more sensitive to change than the total score. Externalizing behavior problems in the child had a strong negative association with several aspects of QoL. Conclusion The CFQL-2 is a brief, reliable scale that effectively measures psychosocial aspects of QoL and is sensitive to changes in QoL in families of children with ASD or related neurodevelopmental disorders. Child externalizing behavior is strongly associated with reductions in multiple aspects of child and family psychosocial QoL. En ligne : https://doi.org/10.1016/j.rasd.2019.101474 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414 [article] Psychometric evaluation of the revised child and family quality of life questionnaire (CFQL-2) [Texte imprimé et/ou numérique] / Thomas W. FRAZIER, Auteur ; Allison C. HYLAND, Auteur ; Leslie A. MARKOWITZ, Auteur ; Leslie L. SPEER, Auteur ; Elizabeth A. DIEKROGER, Auteur . - p.101474. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 70 (February 2020) . - p.101474 Mots-clés : Autism  Quality of life  Neurodevelopmental  Sensitivity to change  Behavior problems Index. décimale : PER Périodiques Résumé : Background The revised Child and Family Quality of Life (CFQL-2) questionnaire was adapted from the original version to be shorter and more sensitive to changes in psychosocial quality of life (QoL) in families of children with Autism Spectrum Disorder (ASD) or related neurodevelopmental conditions. The present study examined the psychometric properties of the CFQL-2. Methods Caregivers of 566 patients presenting to an ASD-specific diagnostic clinic completed the CFQL-2 and other behavioral measurements as part of a diagnostic evaluation. Psychometric properties, including factor structure, internal consistency reliability, reliability across the latent trait, relationships with other clinical measures, and ASD vs. non-ASD group differences were examined for the total score and each subscale. Test-retest reliability and sensitivity to change were evaluated in a separate sleep intervention trial. Results Results indicated that the CFQL-2 reliably measured eight independent QoL domains (Child, Family, Caregiver, Financial, Social Network, Partner Relationship, Coping, and QoL Change), with good-to-excellent reliability across score ranges, good test-retest reliability, and expected relationships with other measures. The change subscale was slightly, but not significantly, more sensitive to change than the total score. Externalizing behavior problems in the child had a strong negative association with several aspects of QoL. Conclusion The CFQL-2 is a brief, reliable scale that effectively measures psychosocial aspects of QoL and is sensitive to changes in QoL in families of children with ASD or related neurodevelopmental disorders. Child externalizing behavior is strongly associated with reductions in multiple aspects of child and family psychosocial QoL. En ligne : https://doi.org/10.1016/j.rasd.2019.101474 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414

Research Review: The strength of the genetic overlap between ADHD and other psychiatric symptoms - a systematic review and meta-analysis / Anneli ANDERSSON in Journal of Child Psychology and Psychiatry, 61-11 (November 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-11 (November 2020) . - p.1173-1183 Titre : Research Review: The strength of the genetic overlap between ADHD and other psychiatric symptoms - a systematic review and meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Anneli ANDERSSON, Auteur ; Catherine TUVBLAD, Auteur ; Qi CHEN, Auteur ; Ebba DU RIETZ, Auteur ; Samuele CORTESE, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Henrik LARSSON, Auteur Article en page(s) : p.1173-1183 Langues : Anglais (eng) Mots-clés : Adhd  externalizing  genetic  internalizing  neurodevelopmental  overlap  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) frequently co-occurs with other psychiatric disorders. Twin studies have established that these co-occurrences are in part due to shared genetic risks. However, the strength of these genetic overlaps and the potential heterogeneity accounted for by type of psychiatric symptoms, age, and methods of assessment remain unclear. We conducted a systematic review to fill this gap. METHODS: We searched PubMed, PsycINFO, Embase, and Web of Science until March 07, 2019. Genetic correlations (r(g) ) were used as effect size measures. RESULTS: A total of 31 independent studies fulfilled the inclusion criteria. The pooled estimates showed that the associations between ADHD and other psychiatric symptoms were partly explained by shared genetic factors, with a pooled genetic correlation of 0.50, 95% confidence interval: 0.46-0.60. The genetic correlations (r(g) ) between ADHD and externalizing (r(g)  = .49 [0.37-0.61]), internalizing (r(g)  = .50 [0.39-0.69]), and neurodevelopmental (r(g)  = .56 [0.47-0.66]) symptoms were similar in magnitude. The genetic correlations in childhood and adulthood were r(g)  = .53 (0.43-0.63) and r(g)  = .51 (0.44-0.56), respectively. For methods of assessment, the genetic correlations were also similar in strength, self-reports r(g)  = .52 (0.47-0.58), other informants r(g)  = .55 (0.41-0.69), and combined raters r(g)  = .50 (0.33-0.65). CONCLUSIONS: These findings indicate that the co-occurrence of externalizing, internalizing, and neurodevelopmental disorder symptoms in individuals with ADHD symptoms in part is due to a shared genetic risk. En ligne : http://dx.doi.org/10.1111/jcpp.13233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 [article] Research Review: The strength of the genetic overlap between ADHD and other psychiatric symptoms - a systematic review and meta-analysis [Texte imprimé et/ou numérique] / Anneli ANDERSSON, Auteur ; Catherine TUVBLAD, Auteur ; Qi CHEN, Auteur ; Ebba DU RIETZ, Auteur ; Samuele CORTESE, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Henrik LARSSON, Auteur . - p.1173-1183. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-11 (November 2020) . - p.1173-1183 Mots-clés : Adhd  externalizing  genetic  internalizing  neurodevelopmental  overlap  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) frequently co-occurs with other psychiatric disorders. Twin studies have established that these co-occurrences are in part due to shared genetic risks. However, the strength of these genetic overlaps and the potential heterogeneity accounted for by type of psychiatric symptoms, age, and methods of assessment remain unclear. We conducted a systematic review to fill this gap. METHODS: We searched PubMed, PsycINFO, Embase, and Web of Science until March 07, 2019. Genetic correlations (r(g) ) were used as effect size measures. RESULTS: A total of 31 independent studies fulfilled the inclusion criteria. The pooled estimates showed that the associations between ADHD and other psychiatric symptoms were partly explained by shared genetic factors, with a pooled genetic correlation of 0.50, 95% confidence interval: 0.46-0.60. The genetic correlations (r(g) ) between ADHD and externalizing (r(g)  = .49 [0.37-0.61]), internalizing (r(g)  = .50 [0.39-0.69]), and neurodevelopmental (r(g)  = .56 [0.47-0.66]) symptoms were similar in magnitude. The genetic correlations in childhood and adulthood were r(g)  = .53 (0.43-0.63) and r(g)  = .51 (0.44-0.56), respectively. For methods of assessment, the genetic correlations were also similar in strength, self-reports r(g)  = .52 (0.47-0.58), other informants r(g)  = .55 (0.41-0.69), and combined raters r(g)  = .50 (0.33-0.65). CONCLUSIONS: These findings indicate that the co-occurrence of externalizing, internalizing, and neurodevelopmental disorder symptoms in individuals with ADHD symptoms in part is due to a shared genetic risk. En ligne : http://dx.doi.org/10.1111/jcpp.13233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434

ADHD and autism symptoms in youth: a network analysis / L. C. FARHAT in Journal of Child Psychology and Psychiatry, 63-2 (February 2022)  

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Assessment of sleep problems and related risk factors observed in Turkish children with Autism spectrum disorders / Tuba MUTLUER in Autism Research, 9-5 (May 2016)  

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Bullying and Autism / Alisa G. WOODS in Autism - Open Access, 3-3 (December 2013)  

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Editorial: The near ubiquity of comorbidity - what are the implications for children's mental health research and practice? / Helen L. FISHER in Journal of Child Psychology and Psychiatry, 63-5 (May 2022)  

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Investigating attention-deficit hyperactivity disorder and autism spectrum disorder traits in the general population: What happens in adult life? / Lucy RIGLIN in Journal of Child Psychology and Psychiatry, 62-4 (April 2021)  

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