8 recherche sur le mot-clé 'cohort study'

Identifying biomarkers and trajectories of executive functions and language development in the first 3 years of life: Design, methods, and findings of the Germina cohort study / Daniel FATORI in Development and Psychopathology, 37-5 (December 2025)  

Public ISBD [article]  inDevelopment and Psychopathology > 37-5 (December 2025) . - p.2457-2467 Titre : Identifying biomarkers and trajectories of executive functions and language development in the first 3 years of life: Design, methods, and findings of the Germina cohort study Type de document : texte imprimé Auteurs : Daniel FATORI, Auteur ; Elizabeth SHEPHARD, Auteur ; Danilo BENETTE, Auteur ; Nathalia Ferrazzo NASPOLINI, Auteur ; Grover Castro GUZMAN, Auteur ; Jaqueline Yu Ting WANG, Auteur ; Pedro TÓTOLO, Auteur ; Anthonieta Looman MAFRA, Auteur ; Caio ISAIAS, Auteur ; Davi Pereira DOS SANTOS, Auteur ; Fabiele Baldino RUSSO, Auteur ; Gerson KOBAYASHI, Auteur ; Adriana ARGEU, Auteur ; Monike TEIXEIRA, Auteur ; Ana Claudia MATTIELLO-SVERZUT, Auteur ; Maria Teresa Bechere FERNANDES, Auteur ; Danila Cristina PETIAN-ALONSO, Auteur ; Helena BRENTANI, Auteur ; Marilia SCLIAR, Auteur ; Paulo Alfonso SCHÃœROFF, Auteur ; Pedro ZUCCOLO, Auteur ; Rogério LERNER, Auteur ; Stephania GERALDINI, Auteur ; Veronica Luiza Vale EUCLYDES, Auteur ; Alicia MATIJASEVICH, Auteur ; Alline Cristina DE CAMPOS, Auteur ; André Carlos Ponce DE CARVALHO, Auteur ; André FUJITA, Auteur ; Carla R. TADDEI, Auteur ; Maria Rita PASSOS-BUENO, Auteur ; Patricia BELTRÃO-BRAGA, Auteur ; Guilherme Vanoni POLANCZYK, Auteur Article en page(s) : p.2457-2467 Langues : Anglais (eng) Mots-clés : child development  cohort study  electroencephalography  genetics  gut microbiome Index. décimale : PER Périodiques Résumé : This paper reports the methods and preliminary findings of Germina, an ongoing cohort study to identify biomarkers and trajectories of executive functions and language development in the first 3 years of life. 557 mother-infant dyads (mean age of mothers 33.7 years, 65.2% white, 48.7% male infants) have undergone baseline and are currently collecting data for other timepoints. A linear regression was used to predict baseline Bayley-III using scores derived from data-driven sparse partial least squares utilizing a multiple holdout framework of 15 domains. Significant associations were found between socioeconomic/demographic characteristics (B = 0.29), epigenetics (B = 0.11), EEG theta (B = 0.14) and beta activity (B = 0.11), and microbiome functional pathways (B = 0.08) domains, and infant development measured by the Bayley-III at T1, suggesting potential interventions to prevent impairments. En ligne : https://dx.doi.org/10.1017/S0954579425000069 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572 [article] Identifying biomarkers and trajectories of executive functions and language development in the first 3 years of life: Design, methods, and findings of the Germina cohort study [texte imprimé] / Daniel FATORI, Auteur ; Elizabeth SHEPHARD, Auteur ; Danilo BENETTE, Auteur ; Nathalia Ferrazzo NASPOLINI, Auteur ; Grover Castro GUZMAN, Auteur ; Jaqueline Yu Ting WANG, Auteur ; Pedro TÓTOLO, Auteur ; Anthonieta Looman MAFRA, Auteur ; Caio ISAIAS, Auteur ; Davi Pereira DOS SANTOS, Auteur ; Fabiele Baldino RUSSO, Auteur ; Gerson KOBAYASHI, Auteur ; Adriana ARGEU, Auteur ; Monike TEIXEIRA, Auteur ; Ana Claudia MATTIELLO-SVERZUT, Auteur ; Maria Teresa Bechere FERNANDES, Auteur ; Danila Cristina PETIAN-ALONSO, Auteur ; Helena BRENTANI, Auteur ; Marilia SCLIAR, Auteur ; Paulo Alfonso SCHÃœROFF, Auteur ; Pedro ZUCCOLO, Auteur ; Rogério LERNER, Auteur ; Stephania GERALDINI, Auteur ; Veronica Luiza Vale EUCLYDES, Auteur ; Alicia MATIJASEVICH, Auteur ; Alline Cristina DE CAMPOS, Auteur ; André Carlos Ponce DE CARVALHO, Auteur ; André FUJITA, Auteur ; Carla R. TADDEI, Auteur ; Maria Rita PASSOS-BUENO, Auteur ; Patricia BELTRÃO-BRAGA, Auteur ; Guilherme Vanoni POLANCZYK, Auteur . - p.2457-2467. Langues : Anglais (eng) in Development and Psychopathology > 37-5 (December 2025) . - p.2457-2467 Mots-clés : child development  cohort study  electroencephalography  genetics  gut microbiome Index. décimale : PER Périodiques Résumé : This paper reports the methods and preliminary findings of Germina, an ongoing cohort study to identify biomarkers and trajectories of executive functions and language development in the first 3 years of life. 557 mother-infant dyads (mean age of mothers 33.7 years, 65.2% white, 48.7% male infants) have undergone baseline and are currently collecting data for other timepoints. A linear regression was used to predict baseline Bayley-III using scores derived from data-driven sparse partial least squares utilizing a multiple holdout framework of 15 domains. Significant associations were found between socioeconomic/demographic characteristics (B = 0.29), epigenetics (B = 0.11), EEG theta (B = 0.14) and beta activity (B = 0.11), and microbiome functional pathways (B = 0.08) domains, and infant development measured by the Bayley-III at T1, suggesting potential interventions to prevent impairments. En ligne : https://dx.doi.org/10.1017/S0954579425000069 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572

Increased Risk of Atopic Diseases in the Siblings of Patients with Autism Spectrum Disorder: A Nationwide Population-Based Cohort Study / Ying-Xiu DAI in Journal of Autism and Developmental Disorders, 49-11 (November 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-11 (November 2019) . - p.4626-4633 Titre : Increased Risk of Atopic Diseases in the Siblings of Patients with Autism Spectrum Disorder: A Nationwide Population-Based Cohort Study Type de document : texte imprimé Auteurs : Ying-Xiu DAI, Auteur ; Ying-Hsuan TAI, Auteur ; Yun-Ting CHANG, Auteur ; Tzeng-Ji CHEN, Auteur ; Meng-Hsiang CHEN, Auteur Article en page(s) : p.4626-4633 Langues : Anglais (eng) Mots-clés : Atopy  Autism spectrum disorder  Cohort study  Epidemiology  Sibling  Taiwan's National Health Insurance Research Database Index. décimale : PER Périodiques Résumé : Several studies have shown a strong association between atopic diseases and autism spectrum disorder (ASD). However, the risk of atopic diseases in individuals having ASD-affected siblings has never been investigated. This nationwide population-based cohort study included 2762 individuals with ASD-affected siblings and 11,048 controls. Diagnoses of atopic diseases, including asthma, atopic dermatitis, allergic rhinitis, and allergic conjunctivitis, were ascertained from 1996 or the birth data to the end of 2011. Individuals with ASD-affected siblings had a higher risk for asthma, atopic dermatitis, allergic rhinitis, allergic conjunctivitis, and multiple atopic diseases compared with controls. In conclusion, individuals with ASD-affected siblings were more likely than were the controls to develop atopic diseases, suggesting shared familial mechanisms underlying the two conditions. En ligne : http://dx.doi.org/10.1007/s10803-019-04184-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=408 [article] Increased Risk of Atopic Diseases in the Siblings of Patients with Autism Spectrum Disorder: A Nationwide Population-Based Cohort Study [texte imprimé] / Ying-Xiu DAI, Auteur ; Ying-Hsuan TAI, Auteur ; Yun-Ting CHANG, Auteur ; Tzeng-Ji CHEN, Auteur ; Meng-Hsiang CHEN, Auteur . - p.4626-4633. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-11 (November 2019) . - p.4626-4633 Mots-clés : Atopy  Autism spectrum disorder  Cohort study  Epidemiology  Sibling  Taiwan's National Health Insurance Research Database Index. décimale : PER Périodiques Résumé : Several studies have shown a strong association between atopic diseases and autism spectrum disorder (ASD). However, the risk of atopic diseases in individuals having ASD-affected siblings has never been investigated. This nationwide population-based cohort study included 2762 individuals with ASD-affected siblings and 11,048 controls. Diagnoses of atopic diseases, including asthma, atopic dermatitis, allergic rhinitis, and allergic conjunctivitis, were ascertained from 1996 or the birth data to the end of 2011. Individuals with ASD-affected siblings had a higher risk for asthma, atopic dermatitis, allergic rhinitis, allergic conjunctivitis, and multiple atopic diseases compared with controls. In conclusion, individuals with ASD-affected siblings were more likely than were the controls to develop atopic diseases, suggesting shared familial mechanisms underlying the two conditions. En ligne : http://dx.doi.org/10.1007/s10803-019-04184-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=408

Trajectories of autistic social traits in childhood and adolescence and disordered eating behaviours at age 14 years: A UK general population cohort study / Francesca SOLMI in Journal of Child Psychology and Psychiatry, 62-1 (January 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-1 (January 2021) . - p.75-85 Titre : Trajectories of autistic social traits in childhood and adolescence and disordered eating behaviours at age 14 years: A UK general population cohort study Type de document : texte imprimé Auteurs : Francesca SOLMI, Auteur ; Francesca BENTIVEGNA, Auteur ; Helen BOULD, Auteur ; William MANDY, Auteur ; Radha KOTHARI, Auteur ; Dheeraj RAI, Auteur ; David SKUSE, Auteur ; Glyn LEWIS, Auteur Article en page(s) : p.75-85 Langues : Anglais (eng) Mots-clés : Alspac  autistic traits  cohort study  eating disorders  trajectories Index. décimale : PER Périodiques Résumé : BACKGROUND: Some people with eating disorders have difficulties with social communication. However, no longitudinal evidence regarding the direction of this association exists. We investigated trajectories of autistic social traits across childhood and adolescence in adolescents with and without disordered eating behaviours in early adolescence. METHODS: We used data from the Avon Longitudinal Study of Parents and Children. Our disordered eating measure indicated presence of any, monthly and weekly disordered eating (fasting, purging, dieting, binge eating) at age 14 years. Autistic social traits were reported by mothers using the Social and Communication Disorders Checklist (SCDC) at age seven, 11, 14 and 16 years. We modelled SCDC score trajectories using multilevel negative binomial models adjusting for a number of child- and maternal-level confounders. RESULTS: Of the 5,381 adolescents included in our sample, 421 (7.8%) experienced one or more disordered eating behaviours, and 148 (2.8%) weekly episodes. Adolescents with disordered eating had a 20% increase in SCDC scores (relative risk (RR) 1.23, 95% confidence interval (CI):1.14, 1.32) compared to those without disordered eating. This association was particularly apparent for those reporting weekly (RR 1.43, 95%CI: 1.27, 1.61) as opposed to monthly disordered eating (RR 1.12, 95%CI: 1.01, 1.22). CONCLUSIONS: Greater autistic social traits in childhood could represent a risk factor for the development of disordered eating in adolescence. Although mechanisms of this association need to be elucidated, clinicians should be aware that autistic social traits could have predated the eating disorder when managing people with these conditions. En ligne : http://dx.doi.org/10.1111/jcpp.13255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435 [article] Trajectories of autistic social traits in childhood and adolescence and disordered eating behaviours at age 14 years: A UK general population cohort study [texte imprimé] / Francesca SOLMI, Auteur ; Francesca BENTIVEGNA, Auteur ; Helen BOULD, Auteur ; William MANDY, Auteur ; Radha KOTHARI, Auteur ; Dheeraj RAI, Auteur ; David SKUSE, Auteur ; Glyn LEWIS, Auteur . - p.75-85. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-1 (January 2021) . - p.75-85 Mots-clés : Alspac  autistic traits  cohort study  eating disorders  trajectories Index. décimale : PER Périodiques Résumé : BACKGROUND: Some people with eating disorders have difficulties with social communication. However, no longitudinal evidence regarding the direction of this association exists. We investigated trajectories of autistic social traits across childhood and adolescence in adolescents with and without disordered eating behaviours in early adolescence. METHODS: We used data from the Avon Longitudinal Study of Parents and Children. Our disordered eating measure indicated presence of any, monthly and weekly disordered eating (fasting, purging, dieting, binge eating) at age 14 years. Autistic social traits were reported by mothers using the Social and Communication Disorders Checklist (SCDC) at age seven, 11, 14 and 16 years. We modelled SCDC score trajectories using multilevel negative binomial models adjusting for a number of child- and maternal-level confounders. RESULTS: Of the 5,381 adolescents included in our sample, 421 (7.8%) experienced one or more disordered eating behaviours, and 148 (2.8%) weekly episodes. Adolescents with disordered eating had a 20% increase in SCDC scores (relative risk (RR) 1.23, 95% confidence interval (CI):1.14, 1.32) compared to those without disordered eating. This association was particularly apparent for those reporting weekly (RR 1.43, 95%CI: 1.27, 1.61) as opposed to monthly disordered eating (RR 1.12, 95%CI: 1.01, 1.22). CONCLUSIONS: Greater autistic social traits in childhood could represent a risk factor for the development of disordered eating in adolescence. Although mechanisms of this association need to be elucidated, clinicians should be aware that autistic social traits could have predated the eating disorder when managing people with these conditions. En ligne : http://dx.doi.org/10.1111/jcpp.13255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435

Preterm birth and risk for language delays before school entry: A sibling-control study / Imac Maria ZAMBRANA in Development and Psychopathology, 33-1 (February 2021)  

Public ISBD [article]  inDevelopment and Psychopathology > 33-1 (February 2021) . - p.47-52 Titre : Preterm birth and risk for language delays before school entry: A sibling-control study Type de document : texte imprimé Auteurs : Imac Maria ZAMBRANA, Auteur ; Margarete E. VOLLRATH, Auteur ; Bo JACOBSSON, Auteur ; Verena SENGPIEL, Auteur ; Eivind YSTRØM, Auteur Article en page(s) : p.47-52 Langues : Anglais (eng) Mots-clés : cohort study  early childhood  language delay  preterm birth  sibling control study Index. décimale : PER Périodiques Résumé : We investigated whether children born preterm are at risk for language delay using a sibling-control design in the Norwegian Mother and Child Cohort Study (MoBa), conducted by the Norwegian Institute of Public Health. Participants included 26,769 siblings born between gestational weeks 23 and 42. Language delay was assessed when the children were 1.5, 3, and 5 years old. To adjust for familial risk factors, comparisons were conducted between preterm and full-term siblings. Pregnancy-specific risk factors were controlled for by means of observed variables. Findings showed that preterm children born before week 37 had increased risk for language delays at 1.5 years. At 3 and 5 years, only children born before week 34 had increased risk for language delay. Children born weeks 29-33 and before week 29 had increased risk for language delay at 1.5 years (RR = 4.51, 95% CI [3.45, 5.88]; RR = 10.32, 95% CI [6.7, 15.80]), 3 years (RR = 1.50, 95% CI [1.02, 2.21]; RR = 2.78, 95% CI [1.09, 7.07]), and 5 years (RR = 1.63, 95% CI [1.06, 2.51]; RR = 2.98, 95% CI [0.87, 10.26]), respectively. In conclusion, children born preterm are at risk for language delays, with familial confounders only explaining a moderate share of the association. This suggests a cause-effect relationship between early preterm birth and risk for language delay in preschool children. En ligne : http://dx.doi.org/10.1017/s0954579419001536 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=442 [article] Preterm birth and risk for language delays before school entry: A sibling-control study [texte imprimé] / Imac Maria ZAMBRANA, Auteur ; Margarete E. VOLLRATH, Auteur ; Bo JACOBSSON, Auteur ; Verena SENGPIEL, Auteur ; Eivind YSTRØM, Auteur . - p.47-52. Langues : Anglais (eng) in Development and Psychopathology > 33-1 (February 2021) . - p.47-52 Mots-clés : cohort study  early childhood  language delay  preterm birth  sibling control study Index. décimale : PER Périodiques Résumé : We investigated whether children born preterm are at risk for language delay using a sibling-control design in the Norwegian Mother and Child Cohort Study (MoBa), conducted by the Norwegian Institute of Public Health. Participants included 26,769 siblings born between gestational weeks 23 and 42. Language delay was assessed when the children were 1.5, 3, and 5 years old. To adjust for familial risk factors, comparisons were conducted between preterm and full-term siblings. Pregnancy-specific risk factors were controlled for by means of observed variables. Findings showed that preterm children born before week 37 had increased risk for language delays at 1.5 years. At 3 and 5 years, only children born before week 34 had increased risk for language delay. Children born weeks 29-33 and before week 29 had increased risk for language delay at 1.5 years (RR = 4.51, 95% CI [3.45, 5.88]; RR = 10.32, 95% CI [6.7, 15.80]), 3 years (RR = 1.50, 95% CI [1.02, 2.21]; RR = 2.78, 95% CI [1.09, 7.07]), and 5 years (RR = 1.63, 95% CI [1.06, 2.51]; RR = 2.98, 95% CI [0.87, 10.26]), respectively. In conclusion, children born preterm are at risk for language delays, with familial confounders only explaining a moderate share of the association. This suggests a cause-effect relationship between early preterm birth and risk for language delay in preschool children. En ligne : http://dx.doi.org/10.1017/s0954579419001536 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=442

Adolescent self-harm with and without suicidality: cross-sectional and longitudinal analyses of a Swedish regional register / Johan BJUREBERG in Journal of Child Psychology and Psychiatry, 60-3 (March 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-3 (March 2019) . - p.295-304 Titre : Adolescent self-harm with and without suicidality: cross-sectional and longitudinal analyses of a Swedish regional register Type de document : texte imprimé Auteurs : Johan BJUREBERG, Auteur ; Anna OHLIS, Auteur ; B. LJOTSSON, Auteur ; Brian M. D'ONOFRIO, Auteur ; E. HEDMAN-LAGERLOF, Auteur ; Jussi JOKINEN, Auteur ; Hanna SAHLIN, Auteur ; Paul LICHTENSTEIN, Auteur ; M. CEDERLOF, Auteur ; Clara HELLNER, Auteur Article en page(s) : p.295-304 Langues : Anglais (eng) Mots-clés : Self-harm  cohort study  epidemiology  self-injurious behavior  suicidal ideation Index. décimale : PER Périodiques Résumé : BACKGROUND: Self-harm is common and there is a need for studies that investigate the relevance of this behavior in clinical samples to inform risk assessment and treatment. The objectives in the current studies were to compare clinical and psychosocial correlates and subsequent adverse outcomes in youth who present to child and adolescent mental health services (CAMHS) with self-harm only (SH), self-harm with suicidality (SH+SU), with those without any indication of SH or SH+SU. METHODS: We conducted a case-control study and a longitudinal cohort study using data from a regional clinical care register, and Swedish national registers. The case-control study included all patients (5-17 years) between 2011 and 2015 (N = 25,161). SH and SH+SU cases were compared with controls (patients without SH) regarding a range of correlates. The longitudinal study included former CAMHS patients (N = 6,120) who were followed for a median time of 2.8 years after termination of CAMHS contact regarding outcomes such as clinical care consumption, social welfare recipiency, and crime conviction. RESULTS: In the case-control study, both the SH and SH+SU groups received more clinical care, had lower global functioning, and higher odds of having mental disorders compared to controls. In most comparisons, the SH+SU group had more problems than the SH group. In the longitudinal study, the same pattern emerged for most outcomes; for example, the adjusted hazard ratio for recurrent care due to self-harm was 23.1 (95% confidence interval [CI], 17.0-31.4) in the SH+SU group compared to 3.9 (95% CI, 2.3-6.7) in the SH group. CONCLUSIONS: Adolescent patients presenting with self-harm have higher risks for adverse outcomes than patients without self-harm. Suicidality in addition to self-harm is associated with more severe outcomes, importantly recurrent episodes of care for self-harm. En ligne : https://dx.doi.org/10.1111/jcpp.12967 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=385 [article] Adolescent self-harm with and without suicidality: cross-sectional and longitudinal analyses of a Swedish regional register [texte imprimé] / Johan BJUREBERG, Auteur ; Anna OHLIS, Auteur ; B. LJOTSSON, Auteur ; Brian M. D'ONOFRIO, Auteur ; E. HEDMAN-LAGERLOF, Auteur ; Jussi JOKINEN, Auteur ; Hanna SAHLIN, Auteur ; Paul LICHTENSTEIN, Auteur ; M. CEDERLOF, Auteur ; Clara HELLNER, Auteur . - p.295-304. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-3 (March 2019) . - p.295-304 Mots-clés : Self-harm  cohort study  epidemiology  self-injurious behavior  suicidal ideation Index. décimale : PER Périodiques Résumé : BACKGROUND: Self-harm is common and there is a need for studies that investigate the relevance of this behavior in clinical samples to inform risk assessment and treatment. The objectives in the current studies were to compare clinical and psychosocial correlates and subsequent adverse outcomes in youth who present to child and adolescent mental health services (CAMHS) with self-harm only (SH), self-harm with suicidality (SH+SU), with those without any indication of SH or SH+SU. METHODS: We conducted a case-control study and a longitudinal cohort study using data from a regional clinical care register, and Swedish national registers. The case-control study included all patients (5-17 years) between 2011 and 2015 (N = 25,161). SH and SH+SU cases were compared with controls (patients without SH) regarding a range of correlates. The longitudinal study included former CAMHS patients (N = 6,120) who were followed for a median time of 2.8 years after termination of CAMHS contact regarding outcomes such as clinical care consumption, social welfare recipiency, and crime conviction. RESULTS: In the case-control study, both the SH and SH+SU groups received more clinical care, had lower global functioning, and higher odds of having mental disorders compared to controls. In most comparisons, the SH+SU group had more problems than the SH group. In the longitudinal study, the same pattern emerged for most outcomes; for example, the adjusted hazard ratio for recurrent care due to self-harm was 23.1 (95% confidence interval [CI], 17.0-31.4) in the SH+SU group compared to 3.9 (95% CI, 2.3-6.7) in the SH group. CONCLUSIONS: Adolescent patients presenting with self-harm have higher risks for adverse outcomes than patients without self-harm. Suicidality in addition to self-harm is associated with more severe outcomes, importantly recurrent episodes of care for self-harm. En ligne : https://dx.doi.org/10.1111/jcpp.12967 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=385

Maternal expressions of warmth and negativity and adolescent mental health: using longitudinal monozygotic twin-difference analyses to approach causal inference / Alice WICKERSHAM in Journal of Child Psychology and Psychiatry, 67-1 (January 2026)  

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Occurrence and predictors of lifetime suicidality and suicidal ideation in autistic adults / M. SIJBRANDIJ ; M. HUIBERS ; Sander BEGEER in Autism, 28-9 (September 2024)  

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Perinatal and sociodemographic factors at birth predicting conduct problems and violence to age 18 years: comparison of Brazilian and British birth cohorts / Joseph MURRAY in Journal of Child Psychology and Psychiatry, 56-8 (August 2015)  

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