Early Social, Imitation, Play, and Language Abilities of Young Non-Autistic Siblings of Children with Autism / Karen TOTH in Journal of Autism and Developmental Disorders, 37-1 (January 2007)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 37-1 (January 2007) . - p.145-157 Titre : Early Social, Imitation, Play, and Language Abilities of Young Non-Autistic Siblings of Children with Autism Type de document : texte imprimé Auteurs : Karen TOTH, Auteur ; Geraldine DAWSON, Auteur ; Andrew N. MELTZOFF, Auteur ; Jessica GREENSON, Auteur ; Deborah A. FEIN, Auteur Année de publication : 2007 Article en page(s) : p.145-157 Langues : Anglais (eng) Mots-clés : Autism Siblings Social Imitation Play Language Index. décimale : PER Périodiques Résumé : Studies are needed to better understand the broad autism phenotype in young siblings of children with autism. Cognitive, adaptive, social, imitation, play, and language abilities were examined in 42 non-autistic siblings and 20 toddlers with no family history of autism, ages 18–27 months. Siblings, as a group, were below average in expressive language and composite IQ, had lower mean receptive language, adaptive behavior, and social communication skills, and used fewer words, distal gestures, and responsive social smiles than comparison children. Additionally, parents reported social impairments in siblings by 13 months of age. These results suggest that the development of young non-autistic siblings is affected at an early age and, thus, should be closely monitored, with appropriate interventions implemented as needed. En ligne : http://dx.doi.org/10.1007/s10803-006-0336-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=621 [article] Early Social, Imitation, Play, and Language Abilities of Young Non-Autistic Siblings of Children with Autism [texte imprimé] / Karen TOTH, Auteur ; Geraldine DAWSON, Auteur ; Andrew N. MELTZOFF, Auteur ; Jessica GREENSON, Auteur ; Deborah A. FEIN, Auteur . - 2007 . - p.145-157. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 37-1 (January 2007) . - p.145-157 Mots-clés : Autism Siblings Social Imitation Play Language Index. décimale : PER Périodiques Résumé : Studies are needed to better understand the broad autism phenotype in young siblings of children with autism. Cognitive, adaptive, social, imitation, play, and language abilities were examined in 42 non-autistic siblings and 20 toddlers with no family history of autism, ages 18–27 months. Siblings, as a group, were below average in expressive language and composite IQ, had lower mean receptive language, adaptive behavior, and social communication skills, and used fewer words, distal gestures, and responsive social smiles than comparison children. Additionally, parents reported social impairments in siblings by 13 months of age. These results suggest that the development of young non-autistic siblings is affected at an early age and, thus, should be closely monitored, with appropriate interventions implemented as needed. En ligne : http://dx.doi.org/10.1007/s10803-006-0336-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=621

Family planning and family vision in mothers after diagnosis of a child with autism spectrum disorder / Noa NAVOT in Autism, 20-5 (July 2016)  

Public ISBD [article]  inAutism > 20-5 (July 2016) . - p.605-615 Titre : Family planning and family vision in mothers after diagnosis of a child with autism spectrum disorder Type de document : texte imprimé Auteurs : Noa NAVOT, Auteur ; Alicia Grattan JORGENSON, Auteur ; Ann VANDER STOEP, Auteur ; Karen TOTH, Auteur ; Sara Jane WEBB, Auteur Article en page(s) : p.605-615 Langues : Anglais (eng) Mots-clés : autism  diagnosis  family functioning and support  family planning  family vision Index. décimale : PER Périodiques Résumé : The diagnosis of a child with autism has short- and long-term impacts on family functioning. With early diagnosis, the diagnostic process is likely to co-occur with family planning decisions, yet little is known about how parents navigate this process. This study explores family planning decision making process among mothers of young children with autism spectrum disorder in the United States, by understanding the transformation in family vision before and after the diagnosis. A total of 22 mothers of first born children, diagnosed with autism between 2 and 4 years of age, were interviewed about family vision prior to and after their child’s diagnosis. Grounded Theory method was used for data analysis. Findings indicated that coherence of early family vision, maternal cognitive flexibility, and maternal responses to diagnosis were highly influential in future family planning decisions. The decision to have additional children reflected a high level of adaptability built upon a solid internalized family model and a flexible approach to life. Decision to stop childrearing reflected a relatively less coherent family model and more rigid cognitive style followed by ongoing hardship managing life after the diagnosis. This report may be useful for health-care providers in enhancing therapeutic alliance and guiding family planning counseling. En ligne : http://dx.doi.org/10.1177/1362361315602134 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290 [article] Family planning and family vision in mothers after diagnosis of a child with autism spectrum disorder [texte imprimé] / Noa NAVOT, Auteur ; Alicia Grattan JORGENSON, Auteur ; Ann VANDER STOEP, Auteur ; Karen TOTH, Auteur ; Sara Jane WEBB, Auteur . - p.605-615. Langues : Anglais (eng) in Autism > 20-5 (July 2016) . - p.605-615 Mots-clés : autism  diagnosis  family functioning and support  family planning  family vision Index. décimale : PER Périodiques Résumé : The diagnosis of a child with autism has short- and long-term impacts on family functioning. With early diagnosis, the diagnostic process is likely to co-occur with family planning decisions, yet little is known about how parents navigate this process. This study explores family planning decision making process among mothers of young children with autism spectrum disorder in the United States, by understanding the transformation in family vision before and after the diagnosis. A total of 22 mothers of first born children, diagnosed with autism between 2 and 4 years of age, were interviewed about family vision prior to and after their child’s diagnosis. Grounded Theory method was used for data analysis. Findings indicated that coherence of early family vision, maternal cognitive flexibility, and maternal responses to diagnosis were highly influential in future family planning decisions. The decision to have additional children reflected a high level of adaptability built upon a solid internalized family model and a flexible approach to life. Decision to stop childrearing reflected a relatively less coherent family model and more rigid cognitive style followed by ongoing hardship managing life after the diagnosis. This report may be useful for health-care providers in enhancing therapeutic alliance and guiding family planning counseling. En ligne : http://dx.doi.org/10.1177/1362361315602134 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290

Head Circumference as an Early Predictor of Autism Symptoms in Younger Siblings of Children with Autism Spectrum Disorder / Lauren ELDER in Journal of Autism and Developmental Disorders, 38-6 (July 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-6 (July 2008) . - p.1104-1111 Titre : Head Circumference as an Early Predictor of Autism Symptoms in Younger Siblings of Children with Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Lauren ELDER, Auteur ; Karen TOTH, Auteur ; Geraldine DAWSON, Auteur ; Jeffrey MUNSON, Auteur ; Deborah A. FEIN, Auteur Année de publication : 2008 Article en page(s) : p.1104-1111 Langues : Anglais (eng) Mots-clés : Autism Head-circumference Infant-siblings Index. décimale : PER Périodiques Résumé : Siblings of children with autism have an increased risk for autism spectrum disorders (ASD). As children with autism often exhibit an atypical trajectory of head circumference (HC) growth, HC may be an indicator of vulnerability to autism. This study investigated whether infant siblings of children with ASD (n = 77) with an atypical trajectory of HC growth were more likely than those without an atypical HC trajectory to develop autism symptoms. Results showed that infants who had larger HC at 12 months, and whose HC growth rate decelerated more rapidly between 12 and 24 months were more likely to exhibit autism symptoms than infants with more typical HC trajectories. Among infant siblings of children with autism, atypical HC growth might alert pediatricians to provide screening and/or referral for further evaluation. En ligne : http://dx.doi.org/10.1007/s10803-007-0495-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Head Circumference as an Early Predictor of Autism Symptoms in Younger Siblings of Children with Autism Spectrum Disorder [texte imprimé] / Lauren ELDER, Auteur ; Karen TOTH, Auteur ; Geraldine DAWSON, Auteur ; Jeffrey MUNSON, Auteur ; Deborah A. FEIN, Auteur . - 2008 . - p.1104-1111. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-6 (July 2008) . - p.1104-1111 Mots-clés : Autism Head-circumference Infant-siblings Index. décimale : PER Périodiques Résumé : Siblings of children with autism have an increased risk for autism spectrum disorders (ASD). As children with autism often exhibit an atypical trajectory of head circumference (HC) growth, HC may be an indicator of vulnerability to autism. This study investigated whether infant siblings of children with ASD (n = 77) with an atypical trajectory of HC growth were more likely than those without an atypical HC trajectory to develop autism symptoms. Results showed that infants who had larger HC at 12 months, and whose HC growth rate decelerated more rapidly between 12 and 24 months were more likely to exhibit autism symptoms than infants with more typical HC trajectories. Among infant siblings of children with autism, atypical HC growth might alert pediatricians to provide screening and/or referral for further evaluation. En ligne : http://dx.doi.org/10.1007/s10803-007-0495-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

Heart rate mean and variability as a biomarker for phenotypic variation in preschoolers with autism spectrum disorder / Tessel BAZELMANS in Autism Research, 12-1 (January 2019)  

Public ISBD [article]  inAutism Research > 12-1 (January 2019) . - p.39-52 Titre : Heart rate mean and variability as a biomarker for phenotypic variation in preschoolers with autism spectrum disorder Type de document : texte imprimé Auteurs : Tessel BAZELMANS, Auteur ; Emily Jane Harrison JONES, Auteur ; Sheila S. GHODS, Auteur ; Sarah CORRIGAN, Auteur ; Karen TOTH, Auteur ; Tony CHARMAN, Auteur ; Sara J. WEBB, Auteur Article en page(s) : p.39-52 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  autonomic control  biomarker  cognition  heart rate  language  reliability Index. décimale : PER Périodiques Résumé : Interest in autonomic arousal in autism spectrum disorder (ASD) is increasing; however, reliability of these measures in ASD is unknown, and previously reported associations with social and cognitive abilities are inconsistent. This study assesses heart rate (HR) and HR variability (HRV) in preschoolers with ASD or typical development (TD) while they passively watched naturalistic videos. Measurement reliability, group differences, and the relationship with social and cognitive abilities were evaluated. Seventy one ASD and 66 TD children (2-4 years) provided cardiac data from two sessions. Test-retest intraclass correlations of HR and HRV over a 3-week period were moderate to good in both groups. Groups did not differ in mean level of HR or HRV. Intra-individual variability of HR between video segments within a session was higher in the ASD group, but intraclass correlations of this metric were low. Higher HR related to better language skills in TD children, but not after accounting for age and nonverbal ability. Higher HRV related to better expressive and receptive language in ASD children after controlling for age and nonverbal ability. HR/HRV were not related to social or executive functioning skills and did not explain any additional variance in abilities at a 12-month follow-up visit. In summary, variation in language abilities is associated with HR in the TD group and HRV in the ASD group. While preliminary, these results are promising for consideration of autonomic control as a biomarker for individual differences in ASD and may help us understand the mechanisms that contribute to communication skills. Autism Research 2019, 12: 39-52. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Cardiac activity, such as heart rate and heart rate variability, is linked to a wide range of psychological functions. This study shows that there is an association between heart rate and heart rate variability and language skills in young children with autism spectrum disorder (ASD). These results may help us understand what underlies individual differences in developmental abilities in young children with ASD. En ligne : http://dx.doi.org/10.1002/aur.1982 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376 [article] Heart rate mean and variability as a biomarker for phenotypic variation in preschoolers with autism spectrum disorder [texte imprimé] / Tessel BAZELMANS, Auteur ; Emily Jane Harrison JONES, Auteur ; Sheila S. GHODS, Auteur ; Sarah CORRIGAN, Auteur ; Karen TOTH, Auteur ; Tony CHARMAN, Auteur ; Sara J. WEBB, Auteur . - p.39-52. Langues : Anglais (eng) in Autism Research > 12-1 (January 2019) . - p.39-52 Mots-clés : autism spectrum disorder  autonomic control  biomarker  cognition  heart rate  language  reliability Index. décimale : PER Périodiques Résumé : Interest in autonomic arousal in autism spectrum disorder (ASD) is increasing; however, reliability of these measures in ASD is unknown, and previously reported associations with social and cognitive abilities are inconsistent. This study assesses heart rate (HR) and HR variability (HRV) in preschoolers with ASD or typical development (TD) while they passively watched naturalistic videos. Measurement reliability, group differences, and the relationship with social and cognitive abilities were evaluated. Seventy one ASD and 66 TD children (2-4 years) provided cardiac data from two sessions. Test-retest intraclass correlations of HR and HRV over a 3-week period were moderate to good in both groups. Groups did not differ in mean level of HR or HRV. Intra-individual variability of HR between video segments within a session was higher in the ASD group, but intraclass correlations of this metric were low. Higher HR related to better language skills in TD children, but not after accounting for age and nonverbal ability. Higher HRV related to better expressive and receptive language in ASD children after controlling for age and nonverbal ability. HR/HRV were not related to social or executive functioning skills and did not explain any additional variance in abilities at a 12-month follow-up visit. In summary, variation in language abilities is associated with HR in the TD group and HRV in the ASD group. While preliminary, these results are promising for consideration of autonomic control as a biomarker for individual differences in ASD and may help us understand the mechanisms that contribute to communication skills. Autism Research 2019, 12: 39-52. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Cardiac activity, such as heart rate and heart rate variability, is linked to a wide range of psychological functions. This study shows that there is an association between heart rate and heart rate variability and language skills in young children with autism spectrum disorder (ASD). These results may help us understand what underlies individual differences in developmental abilities in young children with ASD. En ligne : http://dx.doi.org/10.1002/aur.1982 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376

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