Altered Dynamics of the fMRI Response to Faces in Individuals with Autism / Natalia M. KLEINHANS in Journal of Autism and Developmental Disorders, 46-1 (January 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.232-241 Titre : Altered Dynamics of the fMRI Response to Faces in Individuals with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Natalia M. KLEINHANS, Auteur ; Todd RICHARDS, Auteur ; Jessica GREENSON, Auteur ; Geraldine DAWSON, Auteur ; Elizabeth H. AYLWARD, Auteur Année de publication : 2016 Article en page(s) : p.232-241 Langues : Anglais (eng) Mots-clés : Habituation  Faces  Houses  Amygdala  Fusiform  Adaptation Index. décimale : PER Périodiques Résumé : Abnormal fMRI habituation in autism spectrum disorders (ASDs) has been proposed as a critical component in social impairment. This study investigated habituation to fearful faces and houses in ASD and whether fMRI measures of brain activity discriminate between ASD and typically developing (TD) controls. Two identical fMRI runs presenting masked fearful faces, houses, and scrambled images were collected. We found significantly slower fMRI responses to fearful faces but not houses in ASD. In addition, the pattern of slow to emerge amygdala activation to faces had robust discriminability [ASD vs. TD; area under the curve (AUC) = .852, p < .001]. In contrast, habituation to houses had no predictive value (AUC = .573, p = .365). Amygdala habituation to emotional faces may be useful for quantifying risk in ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2565-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] Altered Dynamics of the fMRI Response to Faces in Individuals with Autism [Texte imprimé et/ou numérique] / Natalia M. KLEINHANS, Auteur ; Todd RICHARDS, Auteur ; Jessica GREENSON, Auteur ; Geraldine DAWSON, Auteur ; Elizabeth H. AYLWARD, Auteur . - 2016 . - p.232-241. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.232-241 Mots-clés : Habituation  Faces  Houses  Amygdala  Fusiform  Adaptation Index. décimale : PER Périodiques Résumé : Abnormal fMRI habituation in autism spectrum disorders (ASDs) has been proposed as a critical component in social impairment. This study investigated habituation to fearful faces and houses in ASD and whether fMRI measures of brain activity discriminate between ASD and typically developing (TD) controls. Two identical fMRI runs presenting masked fearful faces, houses, and scrambled images were collected. We found significantly slower fMRI responses to fearful faces but not houses in ASD. In addition, the pattern of slow to emerge amygdala activation to faces had robust discriminability [ASD vs. TD; area under the curve (AUC) = .852, p < .001]. In contrast, habituation to houses had no predictive value (AUC = .573, p = .365). Amygdala habituation to emotional faces may be useful for quantifying risk in ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2565-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

Characteristics Associated with Presence of Depressive Symptoms in Adults with Autism Spectrum Disorder / Lindsey STERLING in Journal of Autism and Developmental Disorders, 38-6 (July 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-6 (July 2008) . - p.1011-1018 Titre : Characteristics Associated with Presence of Depressive Symptoms in Adults with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Lindsey STERLING, Auteur ; Geraldine DAWSON, Auteur ; Jessica GREENSON, Auteur ; Annette ESTES, Auteur Année de publication : 2008 Article en page(s) : p.1011-1018 Langues : Anglais (eng) Mots-clés : Autism Depression Anxiety Comorbidity Associated-psychopathology Cognitive-ability Index. décimale : PER Périodiques Résumé : Evidence suggests that individuals with autism spectrum disorders (ASD) often exhibit associated psychiatric symptoms, particularly related to depression. The current study investigated whether individual characteristics, specifically, severity of ASD symptoms, level of cognitive ability, and/or presence of other psychiatric disorders, are associated with occurrence of depressive symptoms in adults with ASD. Forty-six adults with ASD were administered a standardized psychiatric history interview. Twenty participants (43%) endorsed depressive symptoms. It was found that individuals with less social impairment, higher cognitive ability, and higher rates of other psychiatric symptoms, were more likely to report depressive symptoms. These characteristics may be vulnerability factors for the development of depression, and should be considered when screening and treating adults with ASD. En ligne : http://dx.doi.org/10.1007/s10803-007-0477-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=473 [article] Characteristics Associated with Presence of Depressive Symptoms in Adults with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Lindsey STERLING, Auteur ; Geraldine DAWSON, Auteur ; Jessica GREENSON, Auteur ; Annette ESTES, Auteur . - 2008 . - p.1011-1018. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-6 (July 2008) . - p.1011-1018 Mots-clés : Autism Depression Anxiety Comorbidity Associated-psychopathology Cognitive-ability Index. décimale : PER Périodiques Résumé : Evidence suggests that individuals with autism spectrum disorders (ASD) often exhibit associated psychiatric symptoms, particularly related to depression. The current study investigated whether individual characteristics, specifically, severity of ASD symptoms, level of cognitive ability, and/or presence of other psychiatric disorders, are associated with occurrence of depressive symptoms in adults with ASD. Forty-six adults with ASD were administered a standardized psychiatric history interview. Twenty participants (43%) endorsed depressive symptoms. It was found that individuals with less social impairment, higher cognitive ability, and higher rates of other psychiatric symptoms, were more likely to report depressive symptoms. These characteristics may be vulnerability factors for the development of depression, and should be considered when screening and treating adults with ASD. En ligne : http://dx.doi.org/10.1007/s10803-007-0477-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=473

Early Social, Imitation, Play, and Language Abilities of Young Non-Autistic Siblings of Children with Autism / Karen TOTH in Journal of Autism and Developmental Disorders, 37-1 (January 2007)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 37-1 (January 2007) . - p.145-157 Titre : Early Social, Imitation, Play, and Language Abilities of Young Non-Autistic Siblings of Children with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Karen TOTH, Auteur ; Geraldine DAWSON, Auteur ; Andrew N. MELTZOFF, Auteur ; Jessica GREENSON, Auteur ; Deborah A. FEIN, Auteur Année de publication : 2007 Article en page(s) : p.145-157 Langues : Anglais (eng) Mots-clés : Autism Siblings Social Imitation Play Language Index. décimale : PER Périodiques Résumé : Studies are needed to better understand the broad autism phenotype in young siblings of children with autism. Cognitive, adaptive, social, imitation, play, and language abilities were examined in 42 non-autistic siblings and 20 toddlers with no family history of autism, ages 18–27 months. Siblings, as a group, were below average in expressive language and composite IQ, had lower mean receptive language, adaptive behavior, and social communication skills, and used fewer words, distal gestures, and responsive social smiles than comparison children. Additionally, parents reported social impairments in siblings by 13 months of age. These results suggest that the development of young non-autistic siblings is affected at an early age and, thus, should be closely monitored, with appropriate interventions implemented as needed. En ligne : http://dx.doi.org/10.1007/s10803-006-0336-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=621 [article] Early Social, Imitation, Play, and Language Abilities of Young Non-Autistic Siblings of Children with Autism [Texte imprimé et/ou numérique] / Karen TOTH, Auteur ; Geraldine DAWSON, Auteur ; Andrew N. MELTZOFF, Auteur ; Jessica GREENSON, Auteur ; Deborah A. FEIN, Auteur . - 2007 . - p.145-157. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 37-1 (January 2007) . - p.145-157 Mots-clés : Autism Siblings Social Imitation Play Language Index. décimale : PER Périodiques Résumé : Studies are needed to better understand the broad autism phenotype in young siblings of children with autism. Cognitive, adaptive, social, imitation, play, and language abilities were examined in 42 non-autistic siblings and 20 toddlers with no family history of autism, ages 18–27 months. Siblings, as a group, were below average in expressive language and composite IQ, had lower mean receptive language, adaptive behavior, and social communication skills, and used fewer words, distal gestures, and responsive social smiles than comparison children. Additionally, parents reported social impairments in siblings by 13 months of age. These results suggest that the development of young non-autistic siblings is affected at an early age and, thus, should be closely monitored, with appropriate interventions implemented as needed. En ligne : http://dx.doi.org/10.1007/s10803-006-0336-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=621

Sleep Problems and Trajectories of Restricted and Repetitive Behaviors in Children with Neurodevelopmental Disabilities / Katherine E. MACDUFFIE in Journal of Autism and Developmental Disorders, 50-11 (November 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-11 (November 2020) . - p.3844-3856 Titre : Sleep Problems and Trajectories of Restricted and Repetitive Behaviors in Children with Neurodevelopmental Disabilities Type de document : Texte imprimé et/ou numérique Auteurs : Katherine E. MACDUFFIE, Auteur ; Jeffrey MUNSON, Auteur ; Jessica GREENSON, Auteur ; Teresa M. WARD, Auteur ; Sally J ROGERS, Auteur ; Geraldine DAWSON, Auteur ; Annette ESTES, Auteur Article en page(s) : p.3844-3856 Langues : Anglais (eng) Mots-clés : Anxiety  Autism spectrum disorder  Developmental delay  Neurodevelopmental disability  Repetitive behaviors  Restricted behaviors  Sleep Index. décimale : PER Périodiques Résumé : Sleep problems are prevalent in children with neurodevelopmental disabilities and are associated with the expression of restricted and repetitive behaviors (RRBs). Children (n?=?57) with autism spectrum disorder (ASD, n?=?38) or developmental delay (DD, n?=?19) participated in multiple assessments of intellectual ability, ASD symptoms, and RRBs (3 timepoints for ASD, 2 for DD). Sleep problems assessed at age 4 via parent report were associated with trajectories of higher-order RRBs (sameness/ritualistic/compulsive behaviors) from age 2-6 in the ASD group, and from age 2-4 in the DD group, even after controlling for intellectual ability, social-affective symptoms, and anxiety. Trajectories of stereotyped/restricted behaviors were unrelated to sleep problems. Sleep problems were associated with trajectories of higher-order (but not lower-order) RRBs in a transdiagnostic sample. En ligne : http://dx.doi.org/10.1007/s10803-020-04438-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432 [article] Sleep Problems and Trajectories of Restricted and Repetitive Behaviors in Children with Neurodevelopmental Disabilities [Texte imprimé et/ou numérique] / Katherine E. MACDUFFIE, Auteur ; Jeffrey MUNSON, Auteur ; Jessica GREENSON, Auteur ; Teresa M. WARD, Auteur ; Sally J ROGERS, Auteur ; Geraldine DAWSON, Auteur ; Annette ESTES, Auteur . - p.3844-3856. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-11 (November 2020) . - p.3844-3856 Mots-clés : Anxiety  Autism spectrum disorder  Developmental delay  Neurodevelopmental disability  Repetitive behaviors  Restricted behaviors  Sleep Index. décimale : PER Périodiques Résumé : Sleep problems are prevalent in children with neurodevelopmental disabilities and are associated with the expression of restricted and repetitive behaviors (RRBs). Children (n?=?57) with autism spectrum disorder (ASD, n?=?38) or developmental delay (DD, n?=?19) participated in multiple assessments of intellectual ability, ASD symptoms, and RRBs (3 timepoints for ASD, 2 for DD). Sleep problems assessed at age 4 via parent report were associated with trajectories of higher-order RRBs (sameness/ritualistic/compulsive behaviors) from age 2-6 in the ASD group, and from age 2-4 in the DD group, even after controlling for intellectual ability, social-affective symptoms, and anxiety. Trajectories of stereotyped/restricted behaviors were unrelated to sleep problems. Sleep problems were associated with trajectories of higher-order (but not lower-order) RRBs in a transdiagnostic sample. En ligne : http://dx.doi.org/10.1007/s10803-020-04438-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432

The effect of early autism intervention on parental sense of efficacy in a randomized trial depends on the initial level of parent stress / Annette ESTES in Autism, 26-7 (October 2022)  

Public ISBD [article]  inAutism > 26-7 (October 2022) . - p.1924-1934 Titre : The effect of early autism intervention on parental sense of efficacy in a randomized trial depends on the initial level of parent stress Type de document : Texte imprimé et/ou numérique Auteurs : Annette ESTES, Auteur ; Paul J. YODER, Auteur ; John MCEACHIN, Auteur ; Gerhard HELLEMANN, Auteur ; Jeffrey MUNSON, Auteur ; Jessica GREENSON, Auteur ; Marie ROCHA, Auteur ; Elizabeth GARDNER, Auteur ; Sally J. ROGERS, Auteur Article en page(s) : p.1924-1934 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  Autistic Disorder/therapy  Child, Preschool  Early Intervention, Educational  Humans  Infant  Parenting  Parents  autism spectrum disorders  efficacy  interventions—psychosocial/behavioral  parent  stress Index. décimale : PER Périodiques Résumé : This is a study of the secondary effects of interventions for young children with autism on their parents. Specifically, we were interested in the impact on parent's sense of efficacy, or how confident and competent a parent feels about themselves as a parent. We tested three ideas: (1) that the style of the intervention, whether it was more or less structured and whether the parent had a more or less formal role, would impact a parent's sense of efficacy; (2) that the intensity of the intervention, how many hours per week the intervention was delivered, would impact parental efficacy; and (3) that the parent's level of stress prior to intervention would impact how intensity and style effected efficacy. We randomly assigned 87 children with autism, age 13-30months, into one of four conditions: 15 versus 25 intervention hours crossed with two different styles of intervention. We used statistical tests to examine these ideas. We found that parental efficacy was related to intervention intensity but not style. Parents with higher stress at the beginning of a 1-year, home-based, comprehensive intervention program had a higher sense of parenting efficacy if their child received lower intensity intervention; parents with lower stress at baseline had a higher sense of efficacy if their child received higher intensity intervention. If a parent can emerge from the process of diagnosis and early intervention with an increased sense that they can make a difference in their child's life (i.e. increased sense of efficacy), it may set the stage for meeting the long-term demands of parenting a child with autism. En ligne : http://dx.doi.org/10.1177/13623613211005613 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=484 [article] The effect of early autism intervention on parental sense of efficacy in a randomized trial depends on the initial level of parent stress [Texte imprimé et/ou numérique] / Annette ESTES, Auteur ; Paul J. YODER, Auteur ; John MCEACHIN, Auteur ; Gerhard HELLEMANN, Auteur ; Jeffrey MUNSON, Auteur ; Jessica GREENSON, Auteur ; Marie ROCHA, Auteur ; Elizabeth GARDNER, Auteur ; Sally J. ROGERS, Auteur . - p.1924-1934. Langues : Anglais (eng) in Autism > 26-7 (October 2022) . - p.1924-1934 Mots-clés : Autism Spectrum Disorder  Autistic Disorder/therapy  Child, Preschool  Early Intervention, Educational  Humans  Infant  Parenting  Parents  autism spectrum disorders  efficacy  interventions—psychosocial/behavioral  parent  stress Index. décimale : PER Périodiques Résumé : This is a study of the secondary effects of interventions for young children with autism on their parents. Specifically, we were interested in the impact on parent's sense of efficacy, or how confident and competent a parent feels about themselves as a parent. We tested three ideas: (1) that the style of the intervention, whether it was more or less structured and whether the parent had a more or less formal role, would impact a parent's sense of efficacy; (2) that the intensity of the intervention, how many hours per week the intervention was delivered, would impact parental efficacy; and (3) that the parent's level of stress prior to intervention would impact how intensity and style effected efficacy. We randomly assigned 87 children with autism, age 13-30months, into one of four conditions: 15 versus 25 intervention hours crossed with two different styles of intervention. We used statistical tests to examine these ideas. We found that parental efficacy was related to intervention intensity but not style. Parents with higher stress at the beginning of a 1-year, home-based, comprehensive intervention program had a higher sense of parenting efficacy if their child received lower intensity intervention; parents with lower stress at baseline had a higher sense of efficacy if their child received higher intensity intervention. If a parent can emerge from the process of diagnosis and early intervention with an increased sense that they can make a difference in their child's life (i.e. increased sense of efficacy), it may set the stage for meeting the long-term demands of parenting a child with autism. En ligne : http://dx.doi.org/10.1177/13623613211005613 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=484

The Impact of Parent-Delivered Intervention on Parents of Very Young Children with Autism / Annette ESTES in Journal of Autism and Developmental Disorders, 44-2 (February 2014)  

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