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Auteur Nicholas H. DE KLERK |
Documents disponibles écrits par cet auteur (5)



A Comparison of Autism Prevalence Trends in Denmark and Western Australia / Erik T. PARNER in Journal of Autism and Developmental Disorders, 41-12 (December 2011)
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Titre : A Comparison of Autism Prevalence Trends in Denmark and Western Australia Type de document : Texte imprimé et/ou numérique Auteurs : Erik T. PARNER, Auteur ; Poul THORSEN, Auteur ; Glenys DIXON, Auteur ; Nicholas H. DE KLERK, Auteur ; Helen LEONARD, Auteur ; Natasha NASSAR, Auteur ; Jenny BOURKE, Auteur ; Carol BOWER, Auteur ; Emma J. GLASSON, Auteur Année de publication : 2011 Article en page(s) : p.1601-1608 Langues : Anglais (eng) Mots-clés : Autism Autism spectrum disorders Prevalence Diagnosis Denmark Western Australia Index. décimale : PER Périodiques Résumé : Prevalence statistics for autism spectrum disorders (ASD) vary widely across geographical boundaries. Some variation can be explained by diagnostic methods, case ascertainment and age at diagnosis. This study compared prevalence statistics for two distinct geographical regions, Denmark and Western Australia, both of which have had population-based registers and consistent classification systems operating over the past decade. Overall ASD prevalence rates were higher in Denmark (68.5 per 10,000 children) compared with Western Australia (51.0 per 10,000 children), while the diagnosis of childhood autism was more prevalent in Western Australia (39.3 per 10,000 children) compared with Denmark (21.8 per 10,000 children). These differences are probably caused by local phenomena affecting case ascertainment but influence from biological or geographical factors may exist. En ligne : http://dx.doi.org/10.1007/s10803-011-1186-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148
in Journal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1601-1608[article] A Comparison of Autism Prevalence Trends in Denmark and Western Australia [Texte imprimé et/ou numérique] / Erik T. PARNER, Auteur ; Poul THORSEN, Auteur ; Glenys DIXON, Auteur ; Nicholas H. DE KLERK, Auteur ; Helen LEONARD, Auteur ; Natasha NASSAR, Auteur ; Jenny BOURKE, Auteur ; Carol BOWER, Auteur ; Emma J. GLASSON, Auteur . - 2011 . - p.1601-1608.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1601-1608
Mots-clés : Autism Autism spectrum disorders Prevalence Diagnosis Denmark Western Australia Index. décimale : PER Périodiques Résumé : Prevalence statistics for autism spectrum disorders (ASD) vary widely across geographical boundaries. Some variation can be explained by diagnostic methods, case ascertainment and age at diagnosis. This study compared prevalence statistics for two distinct geographical regions, Denmark and Western Australia, both of which have had population-based registers and consistent classification systems operating over the past decade. Overall ASD prevalence rates were higher in Denmark (68.5 per 10,000 children) compared with Western Australia (51.0 per 10,000 children), while the diagnosis of childhood autism was more prevalent in Western Australia (39.3 per 10,000 children) compared with Denmark (21.8 per 10,000 children). These differences are probably caused by local phenomena affecting case ascertainment but influence from biological or geographical factors may exist. En ligne : http://dx.doi.org/10.1007/s10803-011-1186-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148 Erratum - Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events / Monique ROBINSON in Development and Psychopathology, 24-1 (January 2012)
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Titre : Erratum - Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events Type de document : Texte imprimé et/ou numérique Auteurs : Monique ROBINSON, Auteur ; Eugen MATTES, Auteur ; Wendy H. ODDY, Auteur ; Craig E. PENNELL, Auteur ; Anke VAN EEKELEN, Auteur ; Neil J. MCLEAN, Auteur ; Peter JACOBY, Auteur ; Jianghong LI, Auteur ; Nicholas H. DE KLERK, Auteur ; Stephen R. ZUBRICK, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur Année de publication : 2012 Article en page(s) : p.333 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579411000861 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152
in Development and Psychopathology > 24-1 (January 2012) . - p.333[article] Erratum - Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events [Texte imprimé et/ou numérique] / Monique ROBINSON, Auteur ; Eugen MATTES, Auteur ; Wendy H. ODDY, Auteur ; Craig E. PENNELL, Auteur ; Anke VAN EEKELEN, Auteur ; Neil J. MCLEAN, Auteur ; Peter JACOBY, Auteur ; Jianghong LI, Auteur ; Nicholas H. DE KLERK, Auteur ; Stephen R. ZUBRICK, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur . - 2012 . - p.333.
Langues : Anglais (eng)
in Development and Psychopathology > 24-1 (January 2012) . - p.333
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579411000861 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152 Mothers of Children with Autism have Different Rates of Cancer According to the Presence of Intellectual Disability in Their Child / Jennifer C. FAIRTHORNE in Journal of Autism and Developmental Disorders, 46-9 (September 2016)
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Titre : Mothers of Children with Autism have Different Rates of Cancer According to the Presence of Intellectual Disability in Their Child Type de document : Texte imprimé et/ou numérique Auteurs : Jennifer C. FAIRTHORNE, Auteur ; Nicholas H. DE KLERK, Auteur ; Helen M. LEONARD, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Article en page(s) : p.3106-3114 Langues : Anglais (eng) Mots-clés : Autism Intellectual disability Cancer Parents Genetics Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental disorders with strong genetic components. Increasingly, research attention has focused on whether genetic factors conveying susceptibility for these conditions, also influence the risk of other health conditions, such as cancer. We examined the occurrence of hospital admissions and treatment/services for cancer in mothers of children with ASD with or without ID compared with other mothers. After linking Western Australian administrative health databases, we used Cox regression to estimate the hazard ratios (HRs) of any hospitalisations and treatment/services for cancer in these groups of mothers. Mothers of children with ASD without ID had greater risk of admissions for cancer (HR 1.29 [95 % CI 1.1, 1.7]), and for treatment/services in particular (HR 1.41 [95 % CI 1.0, 2.0]), than mothers of children with no ASD/ID, while mothers of children with ASD with ID were no more likely to have a cancer-related hospital admission than other mothers. Mothers of children with autism without ID had increased risk of cancer, which may relate to common genetic pathways. En ligne : http://dx.doi.org/10.1007/s10803-016-2847-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292
in Journal of Autism and Developmental Disorders > 46-9 (September 2016) . - p.3106-3114[article] Mothers of Children with Autism have Different Rates of Cancer According to the Presence of Intellectual Disability in Their Child [Texte imprimé et/ou numérique] / Jennifer C. FAIRTHORNE, Auteur ; Nicholas H. DE KLERK, Auteur ; Helen M. LEONARD, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - p.3106-3114.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 46-9 (September 2016) . - p.3106-3114
Mots-clés : Autism Intellectual disability Cancer Parents Genetics Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental disorders with strong genetic components. Increasingly, research attention has focused on whether genetic factors conveying susceptibility for these conditions, also influence the risk of other health conditions, such as cancer. We examined the occurrence of hospital admissions and treatment/services for cancer in mothers of children with ASD with or without ID compared with other mothers. After linking Western Australian administrative health databases, we used Cox regression to estimate the hazard ratios (HRs) of any hospitalisations and treatment/services for cancer in these groups of mothers. Mothers of children with ASD without ID had greater risk of admissions for cancer (HR 1.29 [95 % CI 1.1, 1.7]), and for treatment/services in particular (HR 1.41 [95 % CI 1.0, 2.0]), than mothers of children with no ASD/ID, while mothers of children with ASD with ID were no more likely to have a cancer-related hospital admission than other mothers. Mothers of children with autism without ID had increased risk of cancer, which may relate to common genetic pathways. En ligne : http://dx.doi.org/10.1007/s10803-016-2847-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292 Pre- and postnatal influences on preschool mental health: a large-scale cohort study / Monique ROBINSON in Journal of Child Psychology and Psychiatry, 49-10 (October 2008)
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Titre : Pre- and postnatal influences on preschool mental health: a large-scale cohort study Type de document : Texte imprimé et/ou numérique Auteurs : Monique ROBINSON, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur ; Stephen R. ZUBRICK, Auteur ; Sven R. SILBURN, Auteur ; Nicholas H. DE KLERK, Auteur ; Garth E. KENDALL, Auteur ; Jianghong LI, Auteur ; Wendy H. ODDY, Auteur ; Eugen MATTES, Auteur Année de publication : 2008 Article en page(s) : p.1118-1128 Langues : Anglais (eng) Mots-clés : Mental-health pre-school-children behavioural-development Raine-Study CBCL Index. décimale : PER Périodiques Résumé : Background: Methodological challenges such as confounding have made the study of the early determinants of mental health morbidity problematic. This study aims to address these challenges in investigating antenatal, perinatal and postnatal risk factors for the development of mental health problems in pre-school children in a cohort of Western Australian children.
Methods: The Raine Study is a prospective cohort study of 2,868 live born children involving 2,979 pregnant women recruited at 18 weeks gestation. Children were followed up at age two and five years. The Child Behaviour Checklist (CBCL) was used to measure child mental health with clinical cut-points, including internalising (withdrawn/depressed) and externalising (aggressive/destructive) behaviours (n = 1707).
Results: Multinomial logistic regression analysis showed that the significant risk factors for behaviour problems at age two were the maternal experience of multiple stress events in pregnancy (OR = 1.20, 95% CI = 1.06, 1.37), smoking during pregnancy (OR = 1.30, 95% CI = 1.06, 1.59) and maternal ethnicity (OR = 3.34, 95% CI = 1.61, 6.96). At age five the experience of multiple stress events (OR = 1.17, 95% CI = 1.08, 1.27), cigarette smoking (OR = 1.19, 95% CI = 1.03, 1.37), male gender (OR = 1.43, 95% CI = 1.02, 2.00), breastfeeding for a shorter time (OR = .97, 95% CI = .94, .99) and multiple baby blues symptoms (OR = 1.08, 95% CI = 1.02, 1.14) were significant predictors of mental health problems.
Conclusions: Early childhood mental health is significantly affected by prenatal events in addition to the child's later environment. Interventions targeting adverse prenatal, perinatal and postnatal influences can be expected to improve mental health outcomes for children in the early years.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01955.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=607
in Journal of Child Psychology and Psychiatry > 49-10 (October 2008) . - p.1118-1128[article] Pre- and postnatal influences on preschool mental health: a large-scale cohort study [Texte imprimé et/ou numérique] / Monique ROBINSON, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur ; Stephen R. ZUBRICK, Auteur ; Sven R. SILBURN, Auteur ; Nicholas H. DE KLERK, Auteur ; Garth E. KENDALL, Auteur ; Jianghong LI, Auteur ; Wendy H. ODDY, Auteur ; Eugen MATTES, Auteur . - 2008 . - p.1118-1128.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 49-10 (October 2008) . - p.1118-1128
Mots-clés : Mental-health pre-school-children behavioural-development Raine-Study CBCL Index. décimale : PER Périodiques Résumé : Background: Methodological challenges such as confounding have made the study of the early determinants of mental health morbidity problematic. This study aims to address these challenges in investigating antenatal, perinatal and postnatal risk factors for the development of mental health problems in pre-school children in a cohort of Western Australian children.
Methods: The Raine Study is a prospective cohort study of 2,868 live born children involving 2,979 pregnant women recruited at 18 weeks gestation. Children were followed up at age two and five years. The Child Behaviour Checklist (CBCL) was used to measure child mental health with clinical cut-points, including internalising (withdrawn/depressed) and externalising (aggressive/destructive) behaviours (n = 1707).
Results: Multinomial logistic regression analysis showed that the significant risk factors for behaviour problems at age two were the maternal experience of multiple stress events in pregnancy (OR = 1.20, 95% CI = 1.06, 1.37), smoking during pregnancy (OR = 1.30, 95% CI = 1.06, 1.59) and maternal ethnicity (OR = 3.34, 95% CI = 1.61, 6.96). At age five the experience of multiple stress events (OR = 1.17, 95% CI = 1.08, 1.27), cigarette smoking (OR = 1.19, 95% CI = 1.03, 1.37), male gender (OR = 1.43, 95% CI = 1.02, 2.00), breastfeeding for a shorter time (OR = .97, 95% CI = .94, .99) and multiple baby blues symptoms (OR = 1.08, 95% CI = 1.02, 1.14) were significant predictors of mental health problems.
Conclusions: Early childhood mental health is significantly affected by prenatal events in addition to the child's later environment. Interventions targeting adverse prenatal, perinatal and postnatal influences can be expected to improve mental health outcomes for children in the early years.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01955.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=607 Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events / Monique ROBINSON in Development and Psychopathology, 23-2 (May 2011)
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[article]
Titre : Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events Type de document : Texte imprimé et/ou numérique Auteurs : Monique ROBINSON, Auteur ; Eugen MATTES, Auteur ; Wendy H. ODDY, Auteur ; Craig E. PENNELL, Auteur ; Anke VAN EEKELEN, Auteur ; Neil J. MCLEAN, Auteur ; Peter JACOBY, Auteur ; Jianghong LI, Auteur ; Nicholas H. DE KLERK, Auteur ; Stephen R. ZUBRICK, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur Année de publication : 2011 Article en page(s) : p.507-520 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The maternal experience of stressful events during pregnancy has been associated with a number of adverse consequences for behavioral development in offspring, but the measurement and interpretation of prenatal stress varies among reported studies. The Raine Study recruited 2900 pregnancies and recorded life stress events experienced by 18 and 34 weeks' gestation along with numerous sociodemographic data. The mother's exposure to life stress events was further documented when the children were followed-up in conjunction with behavioral assessments at ages 2, 5, 8, 10, and 14 years using the Child Behavior Checklist. The maternal experience of multiple stressful events during pregnancy was associated with subsequent behavioral problems for offspring. Independent (e.g., death of a relative, job loss) and dependent stress events (e.g., financial problems, marital problems) were both significantly associated with a greater incidence of mental health morbidity between age 2 and 14 years. Exposure to stressful events in the first 18 weeks of pregnancy showed similar associations with subsequent total and externalizing morbidity to events reported at 34 weeks of gestation. These results were independent of postnatal stress exposure. Improved support for women with chronic stress exposure during pregnancy may improve the mental health of their offspring in later life. En ligne : http://dx.doi.org/10.1017/S0954579411000241 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121
in Development and Psychopathology > 23-2 (May 2011) . - p.507-520[article] Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events [Texte imprimé et/ou numérique] / Monique ROBINSON, Auteur ; Eugen MATTES, Auteur ; Wendy H. ODDY, Auteur ; Craig E. PENNELL, Auteur ; Anke VAN EEKELEN, Auteur ; Neil J. MCLEAN, Auteur ; Peter JACOBY, Auteur ; Jianghong LI, Auteur ; Nicholas H. DE KLERK, Auteur ; Stephen R. ZUBRICK, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur . - 2011 . - p.507-520.
Langues : Anglais (eng)
in Development and Psychopathology > 23-2 (May 2011) . - p.507-520
Index. décimale : PER Périodiques Résumé : The maternal experience of stressful events during pregnancy has been associated with a number of adverse consequences for behavioral development in offspring, but the measurement and interpretation of prenatal stress varies among reported studies. The Raine Study recruited 2900 pregnancies and recorded life stress events experienced by 18 and 34 weeks' gestation along with numerous sociodemographic data. The mother's exposure to life stress events was further documented when the children were followed-up in conjunction with behavioral assessments at ages 2, 5, 8, 10, and 14 years using the Child Behavior Checklist. The maternal experience of multiple stressful events during pregnancy was associated with subsequent behavioral problems for offspring. Independent (e.g., death of a relative, job loss) and dependent stress events (e.g., financial problems, marital problems) were both significantly associated with a greater incidence of mental health morbidity between age 2 and 14 years. Exposure to stressful events in the first 18 weeks of pregnancy showed similar associations with subsequent total and externalizing morbidity to events reported at 34 weeks of gestation. These results were independent of postnatal stress exposure. Improved support for women with chronic stress exposure during pregnancy may improve the mental health of their offspring in later life. En ligne : http://dx.doi.org/10.1017/S0954579411000241 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121