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Auteur Christina M. HULTMAN |
Documents disponibles écrits par cet auteur (3)



Parental and Perinatal Risk Factors for Autism: Epidemiological Findings and Potential Mechanisms / Sven SANDIN
Titre : Parental and Perinatal Risk Factors for Autism: Epidemiological Findings and Potential Mechanisms Type de document : Texte imprimé et/ou numérique Auteurs : Sven SANDIN, Auteur ; Alexander KOLEVZON, Auteur ; Stephen Z. LEVINE, Auteur ; Christina M. HULTMAN, Auteur ; Abraham REICHENBERG, Auteur Année de publication : 2013 Importance : p.195-202 Langues : Anglais (eng) Index. décimale : SCI-D SCI-D - Neurosciences Résumé : There is evidence that non-heritable familial pre- or perinatal factors play a role in the etiology of autism and autism spectrum disorders (ASD). According to current evidence from epidemiological studies, two groups of factors show a consistent relationship with ASD: advancing parental age and preterm birth and intrauterine growth restriction. Using a systematic review and meta-analysis of epidemiological studies incorporating a comprehensive assessment of risk factors, we have examined the evidence for an association between advancing parental age, low birth weight, preterm birth and being born small for gestational age, and risk for ASD in the offspring. Advancing maternal age (35 or older), and paternal age (40 or older), show a consistent relationship with ASD. Current evidence also supports a relationship between low birth weight (lt; 2,500 grams), preterm birth (lt; 37 weeks) and being born small for gestational age, and ASD. Future research should continue to examine these variables using large, population-based cohorts in order to offer a more refined modeling of risk and potential confounders, and to attempt to distinguish between autism and spectrum disorders. Identifying common and unique risk factors may be important to understand shared and non-shared etiologies. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=189 Parental and Perinatal Risk Factors for Autism: Epidemiological Findings and Potential Mechanisms [Texte imprimé et/ou numérique] / Sven SANDIN, Auteur ; Alexander KOLEVZON, Auteur ; Stephen Z. LEVINE, Auteur ; Christina M. HULTMAN, Auteur ; Abraham REICHENBERG, Auteur . - 2013 . - p.195-202.
Langues : Anglais (eng)
Index. décimale : SCI-D SCI-D - Neurosciences Résumé : There is evidence that non-heritable familial pre- or perinatal factors play a role in the etiology of autism and autism spectrum disorders (ASD). According to current evidence from epidemiological studies, two groups of factors show a consistent relationship with ASD: advancing parental age and preterm birth and intrauterine growth restriction. Using a systematic review and meta-analysis of epidemiological studies incorporating a comprehensive assessment of risk factors, we have examined the evidence for an association between advancing parental age, low birth weight, preterm birth and being born small for gestational age, and risk for ASD in the offspring. Advancing maternal age (35 or older), and paternal age (40 or older), show a consistent relationship with ASD. Current evidence also supports a relationship between low birth weight (lt; 2,500 grams), preterm birth (lt; 37 weeks) and being born small for gestational age, and ASD. Future research should continue to examine these variables using large, population-based cohorts in order to offer a more refined modeling of risk and potential confounders, and to attempt to distinguish between autism and spectrum disorders. Identifying common and unique risk factors may be important to understand shared and non-shared etiologies. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=189 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire The International Collaboration for Autism Registry Epidemiology (iCARE): Multinational Registry-Based Investigations of Autism Risk Factors and Trends / Diana SCHENDEL in Journal of Autism and Developmental Disorders, 43-11 (November 2013)
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Titre : The International Collaboration for Autism Registry Epidemiology (iCARE): Multinational Registry-Based Investigations of Autism Risk Factors and Trends Type de document : Texte imprimé et/ou numérique Auteurs : Diana SCHENDEL, Auteur ; Michaeline BRESNAHAN, Auteur ; Kim W. CARTER, Auteur ; Richard W. FRANCIS, Auteur ; Mika GISSLER, Auteur ; Therese K. GRONBORG, Auteur ; Raz GROSS, Auteur ; Nina GUNNES, Auteur ; Mady HORNIG, Auteur ; Christina M. HULTMAN, Auteur ; Amanda LANGRIDGE, Auteur ; Marlene B. LAURITSEN, Auteur ; Helen LEONARD, Auteur ; Erik T. PARNER, Auteur ; Abraham REICHENBERG, Auteur ; Sven SANDIN, Auteur ; Andre SOURANDER, Auteur ; Camilla STOLTENBERG, Auteur ; Auli SUOMINEN, Auteur ; Pål SUREN, Auteur ; Ezra SUSSER, Auteur Article en page(s) : p.2650-2663 Langues : Anglais (eng) Mots-clés : Autism Epidemiology Study methods Risk factors Multinational Index. décimale : PER Périodiques Résumé : The International Collaboration for Autism Registry Epidemiology (iCARE) is the first multinational research consortium (Australia, Denmark, Finland, Israel, Norway, Sweden, USA) to promote research in autism geographical and temporal heterogeneity, phenotype, family and life course patterns, and etiology. iCARE devised solutions to challenges in multinational collaboration concerning data access security, confidentiality and management. Data are obtained by integrating existing national or state-wide, population-based, individual-level data systems and undergo rigorous harmonization and quality control processes. Analyses are performed using database federation via a computational infrastructure with a secure, web-based, interface. iCARE provides a unique, unprecedented resource in autism research that will significantly enhance the ability to detect environmental and genetic contributions to the causes and life course of autism. En ligne : http://dx.doi.org/10.1007/s10803-013-1815-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217
in Journal of Autism and Developmental Disorders > 43-11 (November 2013) . - p.2650-2663[article] The International Collaboration for Autism Registry Epidemiology (iCARE): Multinational Registry-Based Investigations of Autism Risk Factors and Trends [Texte imprimé et/ou numérique] / Diana SCHENDEL, Auteur ; Michaeline BRESNAHAN, Auteur ; Kim W. CARTER, Auteur ; Richard W. FRANCIS, Auteur ; Mika GISSLER, Auteur ; Therese K. GRONBORG, Auteur ; Raz GROSS, Auteur ; Nina GUNNES, Auteur ; Mady HORNIG, Auteur ; Christina M. HULTMAN, Auteur ; Amanda LANGRIDGE, Auteur ; Marlene B. LAURITSEN, Auteur ; Helen LEONARD, Auteur ; Erik T. PARNER, Auteur ; Abraham REICHENBERG, Auteur ; Sven SANDIN, Auteur ; Andre SOURANDER, Auteur ; Camilla STOLTENBERG, Auteur ; Auli SUOMINEN, Auteur ; Pål SUREN, Auteur ; Ezra SUSSER, Auteur . - p.2650-2663.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 43-11 (November 2013) . - p.2650-2663
Mots-clés : Autism Epidemiology Study methods Risk factors Multinational Index. décimale : PER Périodiques Résumé : The International Collaboration for Autism Registry Epidemiology (iCARE) is the first multinational research consortium (Australia, Denmark, Finland, Israel, Norway, Sweden, USA) to promote research in autism geographical and temporal heterogeneity, phenotype, family and life course patterns, and etiology. iCARE devised solutions to challenges in multinational collaboration concerning data access security, confidentiality and management. Data are obtained by integrating existing national or state-wide, population-based, individual-level data systems and undergo rigorous harmonization and quality control processes. Analyses are performed using database federation via a computational infrastructure with a secure, web-based, interface. iCARE provides a unique, unprecedented resource in autism research that will significantly enhance the ability to detect environmental and genetic contributions to the causes and life course of autism. En ligne : http://dx.doi.org/10.1007/s10803-013-1815-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217 Trajectories leading to autism spectrum disorders are affected by paternal age: findings from two nationally representative twin studies / Sebastian LUNDSTROM in Journal of Child Psychology and Psychiatry, 51-7 (July 2010)
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Titre : Trajectories leading to autism spectrum disorders are affected by paternal age: findings from two nationally representative twin studies Type de document : Texte imprimé et/ou numérique Auteurs : Sebastian LUNDSTROM, Auteur ; Christopher GILLBERG, Auteur ; Henrik ANCKARSATER, Auteur ; Christina M. HULTMAN, Auteur ; Eva CARLSTROM, Auteur ; Abraham REICHENBERG, Auteur ; Jonathan MILL, Auteur ; Angelica RONALD, Auteur ; Robert PLOMIN, Auteur ; Maria RASTAM, Auteur ; Paul LICHTENSTEIN, Auteur ; Claire Margaret Alison HAWORTH, Auteur Année de publication : 2010 Article en page(s) : p.850-856 Langues : Anglais (eng) Mots-clés : Autism-spectrum-disorders paternal-age autistic-traits behavioral-genetics Index. décimale : PER Périodiques Résumé : Background: Despite extensive efforts, the causes of autism remain unknown. Advancing paternal age has been associated with various neurodevelopmental disorders. We aim to investigate three unresolved questions: (a) What is the association between paternal age and autism spectrum disorders (ASD)?; (b) Does paternal age moderate the genetic and environmental etiological factors for ASD? (c) Does paternal age affect normal variation in autistic-like traits?
Methods: Two nationally representative twin studies from Sweden (n = 11, 122, assessed at age 9 or 12) and the UK (n = 13, 524, assessed at age 9) were used. Categorical and continuous measures of ASD, autistic-like traits and autistic similarity were calculated and compared over paternal age categories.
Results: Both cohorts showed a strong association between paternal age and the risk for ASD. A U-shaped risk association could be discerned since the offspring of both the youngest and oldest fathers showed an elevation in the risk for ASD. Autistic similarity increased with advancing paternal age in both monozygotic and dizygotic twins. Both cohorts showed significantly higher autistic-like traits in the offspring of the youngest and oldest fathers.
Conclusions: Phenomena associated with paternal age are clearly involved in the trajectories leading to autistic-like traits and ASD. Mechanisms influencing the trajectories might differ between older and younger fathers. Molecular genetic studies are now needed in order to further understand the association between paternal age and ASD, as well as normal variation in social, language, and repetitive behaviors in the general population.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02223.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=102
in Journal of Child Psychology and Psychiatry > 51-7 (July 2010) . - p.850-856[article] Trajectories leading to autism spectrum disorders are affected by paternal age: findings from two nationally representative twin studies [Texte imprimé et/ou numérique] / Sebastian LUNDSTROM, Auteur ; Christopher GILLBERG, Auteur ; Henrik ANCKARSATER, Auteur ; Christina M. HULTMAN, Auteur ; Eva CARLSTROM, Auteur ; Abraham REICHENBERG, Auteur ; Jonathan MILL, Auteur ; Angelica RONALD, Auteur ; Robert PLOMIN, Auteur ; Maria RASTAM, Auteur ; Paul LICHTENSTEIN, Auteur ; Claire Margaret Alison HAWORTH, Auteur . - 2010 . - p.850-856.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 51-7 (July 2010) . - p.850-856
Mots-clés : Autism-spectrum-disorders paternal-age autistic-traits behavioral-genetics Index. décimale : PER Périodiques Résumé : Background: Despite extensive efforts, the causes of autism remain unknown. Advancing paternal age has been associated with various neurodevelopmental disorders. We aim to investigate three unresolved questions: (a) What is the association between paternal age and autism spectrum disorders (ASD)?; (b) Does paternal age moderate the genetic and environmental etiological factors for ASD? (c) Does paternal age affect normal variation in autistic-like traits?
Methods: Two nationally representative twin studies from Sweden (n = 11, 122, assessed at age 9 or 12) and the UK (n = 13, 524, assessed at age 9) were used. Categorical and continuous measures of ASD, autistic-like traits and autistic similarity were calculated and compared over paternal age categories.
Results: Both cohorts showed a strong association between paternal age and the risk for ASD. A U-shaped risk association could be discerned since the offspring of both the youngest and oldest fathers showed an elevation in the risk for ASD. Autistic similarity increased with advancing paternal age in both monozygotic and dizygotic twins. Both cohorts showed significantly higher autistic-like traits in the offspring of the youngest and oldest fathers.
Conclusions: Phenomena associated with paternal age are clearly involved in the trajectories leading to autistic-like traits and ASD. Mechanisms influencing the trajectories might differ between older and younger fathers. Molecular genetic studies are now needed in order to further understand the association between paternal age and ASD, as well as normal variation in social, language, and repetitive behaviors in the general population.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02223.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=102