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Auteur Nina GUNNES |
Documents disponibles écrits par cet auteur (2)



The influence of parental concern on the utility of autism diagnostic instruments / Karoline Alexandra HAVDAHL in Autism Research, 10-10 (October 2017)
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[article]
Titre : The influence of parental concern on the utility of autism diagnostic instruments Type de document : Texte imprimé et/ou numérique Auteurs : Karoline Alexandra HAVDAHL, Auteur ; Somer L. BISHOP, Auteur ; Pål SUREN, Auteur ; Anne-Siri ØYEN, Auteur ; Catherine LORD, Auteur ; Andrew PICKLES, Auteur ; Stephen VON TETZCHNER, Auteur ; Synnve SCHJØLBERG, Auteur ; Nina GUNNES, Auteur ; Mady HORNIG, Auteur ; W. Ian LIPKIN, Auteur ; Ezra SUSSER, Auteur ; Michaeline BRESNAHAN, Auteur ; Per MAGNUS, Auteur ; Nina STENBERG, Auteur ; Ted REICHBORN-KJENNERUD, Auteur ; Camilla STOLTENBERG, Auteur Article en page(s) : p.1672-1686 Langues : Anglais (eng) Mots-clés : Autism Diagnostic Interview-Revised Autism Diagnostic Observation Schedule early diagnosis screening Index. décimale : PER Périodiques Résumé : The parental report-based Autism Diagnostic Interview-Revised (ADI-R) and the clinician observation-based Autism Diagnostic Observation Schedule (ADOS) have been validated primarily in U.S. clinics specialized in autism spectrum disorder (ASD), in which most children are referred by their parents because of ASD concern. This study assessed diagnostic agreement of the ADOS-2 and ADI-R toddler algorithms in a more broadly based sample of 679 toddlers (age 35–47 months) from the Norwegian Mother and Child Cohort. We also examined whether parental concern about ASD influenced instrument performance, comparing toddlers identified based on parental ASD concern (n?=?48) and parent-reported signs of developmental problems (screening) without a specific concern about ASD (n?=?400). The ADOS cutoffs showed consistently well-balanced sensitivity and specificity. The ADI-R cutoffs demonstrated good specificity, but reduced sensitivity, missing 43% of toddlers whose parents were not specifically concerned about ASD. The ADI-R and ADOS dimensional scores agreed well with clinical diagnoses (area under the curve???0.85), contributing additively to their prediction. On the ADI-R, different cutoffs were needed according to presence or absence of parental ASD concern, in order to achieve comparable balance of sensitivity and specificity. These results highlight the importance of taking parental concern about ASD into account when interpreting scores from parental report-based instruments such as the ADI-R. While the ADOS cutoffs performed consistently well, the additive contributions of ADI-R and ADOS scores to the prediction of ASD diagnosis underscore the value of combining instruments based on parent accounts and clinician observation in evaluation of ASD. Autism Res 2017, 10: 1672–1686. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1817 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1672-1686[article] The influence of parental concern on the utility of autism diagnostic instruments [Texte imprimé et/ou numérique] / Karoline Alexandra HAVDAHL, Auteur ; Somer L. BISHOP, Auteur ; Pål SUREN, Auteur ; Anne-Siri ØYEN, Auteur ; Catherine LORD, Auteur ; Andrew PICKLES, Auteur ; Stephen VON TETZCHNER, Auteur ; Synnve SCHJØLBERG, Auteur ; Nina GUNNES, Auteur ; Mady HORNIG, Auteur ; W. Ian LIPKIN, Auteur ; Ezra SUSSER, Auteur ; Michaeline BRESNAHAN, Auteur ; Per MAGNUS, Auteur ; Nina STENBERG, Auteur ; Ted REICHBORN-KJENNERUD, Auteur ; Camilla STOLTENBERG, Auteur . - p.1672-1686.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1672-1686
Mots-clés : Autism Diagnostic Interview-Revised Autism Diagnostic Observation Schedule early diagnosis screening Index. décimale : PER Périodiques Résumé : The parental report-based Autism Diagnostic Interview-Revised (ADI-R) and the clinician observation-based Autism Diagnostic Observation Schedule (ADOS) have been validated primarily in U.S. clinics specialized in autism spectrum disorder (ASD), in which most children are referred by their parents because of ASD concern. This study assessed diagnostic agreement of the ADOS-2 and ADI-R toddler algorithms in a more broadly based sample of 679 toddlers (age 35–47 months) from the Norwegian Mother and Child Cohort. We also examined whether parental concern about ASD influenced instrument performance, comparing toddlers identified based on parental ASD concern (n?=?48) and parent-reported signs of developmental problems (screening) without a specific concern about ASD (n?=?400). The ADOS cutoffs showed consistently well-balanced sensitivity and specificity. The ADI-R cutoffs demonstrated good specificity, but reduced sensitivity, missing 43% of toddlers whose parents were not specifically concerned about ASD. The ADI-R and ADOS dimensional scores agreed well with clinical diagnoses (area under the curve???0.85), contributing additively to their prediction. On the ADI-R, different cutoffs were needed according to presence or absence of parental ASD concern, in order to achieve comparable balance of sensitivity and specificity. These results highlight the importance of taking parental concern about ASD into account when interpreting scores from parental report-based instruments such as the ADI-R. While the ADOS cutoffs performed consistently well, the additive contributions of ADI-R and ADOS scores to the prediction of ASD diagnosis underscore the value of combining instruments based on parent accounts and clinician observation in evaluation of ASD. Autism Res 2017, 10: 1672–1686. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1817 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 The International Collaboration for Autism Registry Epidemiology (iCARE): Multinational Registry-Based Investigations of Autism Risk Factors and Trends / Diana SCHENDEL in Journal of Autism and Developmental Disorders, 43-11 (November 2013)
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[article]
Titre : The International Collaboration for Autism Registry Epidemiology (iCARE): Multinational Registry-Based Investigations of Autism Risk Factors and Trends Type de document : Texte imprimé et/ou numérique Auteurs : Diana SCHENDEL, Auteur ; Michaeline BRESNAHAN, Auteur ; Kim W. CARTER, Auteur ; Richard W. FRANCIS, Auteur ; Mika GISSLER, Auteur ; Therese K. GRONBORG, Auteur ; Raz GROSS, Auteur ; Nina GUNNES, Auteur ; Mady HORNIG, Auteur ; Christina M. HULTMAN, Auteur ; Amanda LANGRIDGE, Auteur ; Marlene B. LAURITSEN, Auteur ; Helen LEONARD, Auteur ; Erik T. PARNER, Auteur ; Abraham REICHENBERG, Auteur ; Sven SANDIN, Auteur ; Andre SOURANDER, Auteur ; Camilla STOLTENBERG, Auteur ; Auli SUOMINEN, Auteur ; Pål SUREN, Auteur ; Ezra SUSSER, Auteur Article en page(s) : p.2650-2663 Langues : Anglais (eng) Mots-clés : Autism Epidemiology Study methods Risk factors Multinational Index. décimale : PER Périodiques Résumé : The International Collaboration for Autism Registry Epidemiology (iCARE) is the first multinational research consortium (Australia, Denmark, Finland, Israel, Norway, Sweden, USA) to promote research in autism geographical and temporal heterogeneity, phenotype, family and life course patterns, and etiology. iCARE devised solutions to challenges in multinational collaboration concerning data access security, confidentiality and management. Data are obtained by integrating existing national or state-wide, population-based, individual-level data systems and undergo rigorous harmonization and quality control processes. Analyses are performed using database federation via a computational infrastructure with a secure, web-based, interface. iCARE provides a unique, unprecedented resource in autism research that will significantly enhance the ability to detect environmental and genetic contributions to the causes and life course of autism. En ligne : http://dx.doi.org/10.1007/s10803-013-1815-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217
in Journal of Autism and Developmental Disorders > 43-11 (November 2013) . - p.2650-2663[article] The International Collaboration for Autism Registry Epidemiology (iCARE): Multinational Registry-Based Investigations of Autism Risk Factors and Trends [Texte imprimé et/ou numérique] / Diana SCHENDEL, Auteur ; Michaeline BRESNAHAN, Auteur ; Kim W. CARTER, Auteur ; Richard W. FRANCIS, Auteur ; Mika GISSLER, Auteur ; Therese K. GRONBORG, Auteur ; Raz GROSS, Auteur ; Nina GUNNES, Auteur ; Mady HORNIG, Auteur ; Christina M. HULTMAN, Auteur ; Amanda LANGRIDGE, Auteur ; Marlene B. LAURITSEN, Auteur ; Helen LEONARD, Auteur ; Erik T. PARNER, Auteur ; Abraham REICHENBERG, Auteur ; Sven SANDIN, Auteur ; Andre SOURANDER, Auteur ; Camilla STOLTENBERG, Auteur ; Auli SUOMINEN, Auteur ; Pål SUREN, Auteur ; Ezra SUSSER, Auteur . - p.2650-2663.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 43-11 (November 2013) . - p.2650-2663
Mots-clés : Autism Epidemiology Study methods Risk factors Multinational Index. décimale : PER Périodiques Résumé : The International Collaboration for Autism Registry Epidemiology (iCARE) is the first multinational research consortium (Australia, Denmark, Finland, Israel, Norway, Sweden, USA) to promote research in autism geographical and temporal heterogeneity, phenotype, family and life course patterns, and etiology. iCARE devised solutions to challenges in multinational collaboration concerning data access security, confidentiality and management. Data are obtained by integrating existing national or state-wide, population-based, individual-level data systems and undergo rigorous harmonization and quality control processes. Analyses are performed using database federation via a computational infrastructure with a secure, web-based, interface. iCARE provides a unique, unprecedented resource in autism research that will significantly enhance the ability to detect environmental and genetic contributions to the causes and life course of autism. En ligne : http://dx.doi.org/10.1007/s10803-013-1815-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217