Female Autism Phenotypes Investigated at Different Levels of Language and Developmental Abilities / Yamini J. HOWE in Journal of Autism and Developmental Disorders, 45-11 (November 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-11 (November 2015) . - p.3537-3549 Titre : Female Autism Phenotypes Investigated at Different Levels of Language and Developmental Abilities Type de document : Texte imprimé et/ou numérique Auteurs : Yamini J. HOWE, Auteur ; Julia A. O’ROURKE, Auteur ; Yvette YATCHMINK, Auteur ; Emma W. VISCIDI, Auteur ; Richard N. JONES, Auteur ; Eric M. MORROW, Auteur Article en page(s) : p.3537-3549 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Sex differences  Diagnosis of autism spectrum disorder Index. décimale : PER Périodiques Résumé : This study investigated the differences in clinical symptoms between females and males with autism spectrum disorder (ASD) across three verbal ability groups (nonverbal, phrase and fluent speech), based on which Autism Diagnostic Observation Schedule module was administered to 5723 individuals in four research datasets. In the Simons Simplex Collection and Autism Treatment Network, females with ASD and phrase or fluent speech had lower cognitive, adaptive, and social abilities than males. In the Autism Genetics Resource Exchange and the Autism Consortium, females with phrase or fluent speech had similar or better adaptive and social abilities than males. Females who were nonverbal had similar cognitive, adaptive, and social abilities as males. Population-based longitudinal studies of verbally fluent females with ASD are needed. En ligne : http://dx.doi.org/10.1007/s10803-015-2501-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270 [article] Female Autism Phenotypes Investigated at Different Levels of Language and Developmental Abilities [Texte imprimé et/ou numérique] / Yamini J. HOWE, Auteur ; Julia A. O’ROURKE, Auteur ; Yvette YATCHMINK, Auteur ; Emma W. VISCIDI, Auteur ; Richard N. JONES, Auteur ; Eric M. MORROW, Auteur . - p.3537-3549. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-11 (November 2015) . - p.3537-3549 Mots-clés : Autism spectrum disorder  Sex differences  Diagnosis of autism spectrum disorder Index. décimale : PER Périodiques Résumé : This study investigated the differences in clinical symptoms between females and males with autism spectrum disorder (ASD) across three verbal ability groups (nonverbal, phrase and fluent speech), based on which Autism Diagnostic Observation Schedule module was administered to 5723 individuals in four research datasets. In the Simons Simplex Collection and Autism Treatment Network, females with ASD and phrase or fluent speech had lower cognitive, adaptive, and social abilities than males. In the Autism Genetics Resource Exchange and the Autism Consortium, females with phrase or fluent speech had similar or better adaptive and social abilities than males. Females who were nonverbal had similar cognitive, adaptive, and social abilities as males. Population-based longitudinal studies of verbally fluent females with ASD are needed. En ligne : http://dx.doi.org/10.1007/s10803-015-2501-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270

The association between epilepsy and autism symptoms and maladaptive behaviors in children with autism spectrum disorder / Emma W. VISCIDI in Autism, 18-8 (November 2014)  

Public ISBD [article]  inAutism > 18-8 (November 2014) . - p.996-1006 Titre : The association between epilepsy and autism symptoms and maladaptive behaviors in children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Emma W. VISCIDI, Auteur ; Ashley L. JOHNSON, Auteur ; Sarah SPENCE, Auteur ; Stephen L. BUKA, Auteur ; Eric M. MORROW, Auteur ; Elizabeth W. TRICHE, Auteur Article en page(s) : p.996-1006 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  autism symptoms  epilepsy  hyperactivity  intellectual disability Index. décimale : PER Périodiques Résumé : Epilepsy is common in children with autism spectrum disorder (ASD) but little is known about how seizures impact the autism phenotype. The association between epilepsy and autism symptoms and associated maladaptive behaviors was examined in 2,645 children with ASD, of whom 139 had epilepsy, from the Simons Simplex Collection. Children with ASD and epilepsy had significantly more autism symptoms and maladaptive behaviors than children without epilepsy. However, after adjusting for IQ, only hyperactivity symptoms remained significantly increased (13% higher) in the epilepsy group. Among children with ASD without co-occurring intellectual disability, children with epilepsy had significantly more irritability (20% higher) and hyperactivity (24% higher) symptoms. This is the largest study to date comparing the autism phenotype in children with ASD with and without epilepsy. Children with ASD and epilepsy showed greater impairment than children without epilepsy, which was mostly explained by the lower IQ of the epilepsy group. These findings have important clinical implications for patients with ASD. En ligne : http://dx.doi.org/10.1177/1362361313508027 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=242 [article] The association between epilepsy and autism symptoms and maladaptive behaviors in children with autism spectrum disorder [Texte imprimé et/ou numérique] / Emma W. VISCIDI, Auteur ; Ashley L. JOHNSON, Auteur ; Sarah SPENCE, Auteur ; Stephen L. BUKA, Auteur ; Eric M. MORROW, Auteur ; Elizabeth W. TRICHE, Auteur . - p.996-1006. Langues : Anglais (eng) in Autism > 18-8 (November 2014) . - p.996-1006 Mots-clés : autism spectrum disorder  autism symptoms  epilepsy  hyperactivity  intellectual disability Index. décimale : PER Périodiques Résumé : Epilepsy is common in children with autism spectrum disorder (ASD) but little is known about how seizures impact the autism phenotype. The association between epilepsy and autism symptoms and associated maladaptive behaviors was examined in 2,645 children with ASD, of whom 139 had epilepsy, from the Simons Simplex Collection. Children with ASD and epilepsy had significantly more autism symptoms and maladaptive behaviors than children without epilepsy. However, after adjusting for IQ, only hyperactivity symptoms remained significantly increased (13% higher) in the epilepsy group. Among children with ASD without co-occurring intellectual disability, children with epilepsy had significantly more irritability (20% higher) and hyperactivity (24% higher) symptoms. This is the largest study to date comparing the autism phenotype in children with ASD with and without epilepsy. Children with ASD and epilepsy showed greater impairment than children without epilepsy, which was mostly explained by the lower IQ of the epilepsy group. These findings have important clinical implications for patients with ASD. En ligne : http://dx.doi.org/10.1177/1362361313508027 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=242

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