37 recherche sur le mot-clé 'Young children'

Aberrant functional connectivity of neural circuits associated with social and sensorimotor deficits in young children with autism spectrum disorder in Autism Research, 11-12 (December 2018)  

Public ISBD [article]  inAutism Research > 11-12 (December 2018) . - p.1643-1652 Titre : Aberrant functional connectivity of neural circuits associated with social and sensorimotor deficits in young children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Article en page(s) : p.1643-1652 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  resting state fMRI  support vector regression analysis  young children Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by atypical functional integration of brain regions. The vast majority of neuroimaging studies of ASD have focused on older children, adolescents, and adults with the disorder. Very little work has explored whole-brain functional connectivity of young children with ASD. Here, we collected resting-state functional magnetic resonance imaging data from 58 young children (mean age 4.98 years; 29 with ASD; 29 matched healthy controls [HC]). All children were under sedation during scanning. A functional "connectedness" method was first used to seek for brain regions showing atypical functional connectivity (FC) in children with ASD. Then, a recurrent-seek strategy was applied to reveal atypical FC circuits in ASD children. FC matrices between regions-of-interest (ROIs) were compared between ASD and HC. Finally, a support vector regression (SVR) method was used to assess the relationship between the FC circuits and ASD symptom severity. Two atypical FC circuits comprising 23 ROIs in ASD were revealed: one predominantly comprised brain regions involved with social cognition showing under-connectivity in ASD; the other predominantly comprised sensory-motor and visual brain regions showing over-connectivity in ASD. The SVR analysis showed that the two FC circuits were separately related to social deficits and restricted behavior scores. These findings indicate disrupted FC of neural circuits involved in the social and sensorimotor processes in young children with ASD. The finding of the atypical FC patterns in young children with ASD underscores the utility of studying younger children with the disorder, and highlights nuanced patterns of brain connectivity underlying behavior closer to disorder onset. Autism Research 2018, 11: 1643-1652. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Autism spectrum disorder (ASD) is an early-onset neurodevelopmental disorder. Understanding brain functional alterations at early ages is important for understanding biological mechanisms of ASD. Here, we found two atypical brain functional circuits in young children with ASD that were related to social and sensorimotor function. These results show how atypical patterns of brain functional connectivity in young children with of ASD may underlie core symptoms of the disorder. En ligne : http://dx.doi.org/10.1002/aur.2029 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3723 [article] Aberrant functional connectivity of neural circuits associated with social and sensorimotor deficits in young children with autism spectrum disorder [Texte imprimé et/ou numérique] . - p.1643-1652. Langues : Anglais (eng) in Autism Research > 11-12 (December 2018) . - p.1643-1652 Mots-clés : autism spectrum disorder  resting state fMRI  support vector regression analysis  young children Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by atypical functional integration of brain regions. The vast majority of neuroimaging studies of ASD have focused on older children, adolescents, and adults with the disorder. Very little work has explored whole-brain functional connectivity of young children with ASD. Here, we collected resting-state functional magnetic resonance imaging data from 58 young children (mean age 4.98 years; 29 with ASD; 29 matched healthy controls [HC]). All children were under sedation during scanning. A functional "connectedness" method was first used to seek for brain regions showing atypical functional connectivity (FC) in children with ASD. Then, a recurrent-seek strategy was applied to reveal atypical FC circuits in ASD children. FC matrices between regions-of-interest (ROIs) were compared between ASD and HC. Finally, a support vector regression (SVR) method was used to assess the relationship between the FC circuits and ASD symptom severity. Two atypical FC circuits comprising 23 ROIs in ASD were revealed: one predominantly comprised brain regions involved with social cognition showing under-connectivity in ASD; the other predominantly comprised sensory-motor and visual brain regions showing over-connectivity in ASD. The SVR analysis showed that the two FC circuits were separately related to social deficits and restricted behavior scores. These findings indicate disrupted FC of neural circuits involved in the social and sensorimotor processes in young children with ASD. The finding of the atypical FC patterns in young children with ASD underscores the utility of studying younger children with the disorder, and highlights nuanced patterns of brain connectivity underlying behavior closer to disorder onset. Autism Research 2018, 11: 1643-1652. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Autism spectrum disorder (ASD) is an early-onset neurodevelopmental disorder. Understanding brain functional alterations at early ages is important for understanding biological mechanisms of ASD. Here, we found two atypical brain functional circuits in young children with ASD that were related to social and sensorimotor function. These results show how atypical patterns of brain functional connectivity in young children with of ASD may underlie core symptoms of the disorder. En ligne : http://dx.doi.org/10.1002/aur.2029 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3723

Adverse event reporting in intervention research for young autistic children / Kristen BOTTEMA-BEUTEL in Autism, 25-2 (February 2021)  

Public ISBD [article]  inAutism > 25-2 (February 2021) . - p.322-335 Titre : Adverse event reporting in intervention research for young autistic children Type de document : Texte imprimé et/ou numérique Auteurs : Kristen BOTTEMA-BEUTEL, Auteur ; Shannon CROWLEY, Auteur ; Micheal SANDBANK, Auteur ; Tiffany G. WOYNAROSKI, Auteur Article en page(s) : p.322-335 Langues : Anglais (eng) Mots-clés : adverse effects  adverse events  autism  harms  intervention  young children Index. décimale : PER Périodiques Résumé : In this study, we looked at published research on interventions for young autistic children that did not involve administering medication. We were interested in determining how often studies reported on whether adverse events (i.e. physical or psychological distress to the participants) or adverse effects (i.e. adverse events that are thought to be caused by the intervention) had occurred. We found that of the 150 reports we examined, only 11 mentioned adverse events. One of these studies reported adverse events occurred, and three reported that adverse effects occurred. We also reviewed the studies to examine the reasons that were given to explain why any participants dropped out of the intervention (termed "withdrawal"), to determine if any of these reasons could be considered adverse events or adverse effects. Fifty-four studies described reasons for withdrawal, and 10 of these studies had reasons that could be categorized as an adverse event, 8 studies had reasons that could be categorized as an adverse effect, and an additional 12 studies had reasons that were too vaguely described to determine whether they were adverse events or not. We recommend that autism intervention researchers develop more systematic methods of looking for and reporting adverse events and effects, so that professionals and families can be better informed when choosing to enroll their autistic children in interventions. En ligne : http://dx.doi.org/10.1177/1362361320965331 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4419 [article] Adverse event reporting in intervention research for young autistic children [Texte imprimé et/ou numérique] / Kristen BOTTEMA-BEUTEL, Auteur ; Shannon CROWLEY, Auteur ; Micheal SANDBANK, Auteur ; Tiffany G. WOYNAROSKI, Auteur . - p.322-335. Langues : Anglais (eng) in Autism > 25-2 (February 2021) . - p.322-335 Mots-clés : adverse effects  adverse events  autism  harms  intervention  young children Index. décimale : PER Périodiques Résumé : In this study, we looked at published research on interventions for young autistic children that did not involve administering medication. We were interested in determining how often studies reported on whether adverse events (i.e. physical or psychological distress to the participants) or adverse effects (i.e. adverse events that are thought to be caused by the intervention) had occurred. We found that of the 150 reports we examined, only 11 mentioned adverse events. One of these studies reported adverse events occurred, and three reported that adverse effects occurred. We also reviewed the studies to examine the reasons that were given to explain why any participants dropped out of the intervention (termed "withdrawal"), to determine if any of these reasons could be considered adverse events or adverse effects. Fifty-four studies described reasons for withdrawal, and 10 of these studies had reasons that could be categorized as an adverse event, 8 studies had reasons that could be categorized as an adverse effect, and an additional 12 studies had reasons that were too vaguely described to determine whether they were adverse events or not. We recommend that autism intervention researchers develop more systematic methods of looking for and reporting adverse events and effects, so that professionals and families can be better informed when choosing to enroll their autistic children in interventions. En ligne : http://dx.doi.org/10.1177/1362361320965331 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4419

Atypical development of the central auditory system in young children with Autism spectrum disorder / Yuko YOSHIMURA in Autism Research, 9-11 (November 2016)  

Public ISBD [article]  inAutism Research > 9-11 (November 2016) . - p.1216-1226 Titre : Atypical development of the central auditory system in young children with Autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Yuko YOSHIMURA, Auteur ; Mitsuru KIKUCHI, Auteur ; Hirotoshi HIRAISHI, Auteur ; Chiaki HASEGAWA, Auteur ; Tetsuya TAKAHASHI, Auteur ; Gerard B. REMIJN, Auteur ; Manabu OI, Auteur ; Toshio MUNESUE, Auteur ; Haruhiro HIGASHIDA, Auteur ; Yoshio MINABE, Auteur ; Haruyuki KOJIMA, Auteur Article en page(s) : p.1216-1226 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  magnetoencephalography  P1m  young children Index. décimale : PER Périodiques Résumé : The P1m component of the auditory evoked magnetic field is the earliest cortical response associated with language acquisition. However, the growth curve of the P1m component is unknown in both typically developing (TD) and atypically developing children. The aim of this study is to clarify the developmental pattern of this component when evoked by binaural human voice stimulation using child-customized magnetoencephalography. A total of 35 young TD children (32–121 months of age) and 35 children with autism spectrum disorder (ASD) (38–111 months of age) participated in this study. This is the first report to demonstrate an inverted U-shaped growth curve for the P1m dipole intensity in the left hemisphere in TD children. In addition, our results revealed a more diversified age-related distribution of auditory brain responses in 3- to 9-year-old children with ASD. These results demonstrate the diversified growth curve of the P1m component in ASD during young childhood, which is a crucial period for first language acquisition. En ligne : http://dx.doi.org/10.1002/aur.1604 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2972 [article] Atypical development of the central auditory system in young children with Autism spectrum disorder [Texte imprimé et/ou numérique] / Yuko YOSHIMURA, Auteur ; Mitsuru KIKUCHI, Auteur ; Hirotoshi HIRAISHI, Auteur ; Chiaki HASEGAWA, Auteur ; Tetsuya TAKAHASHI, Auteur ; Gerard B. REMIJN, Auteur ; Manabu OI, Auteur ; Toshio MUNESUE, Auteur ; Haruhiro HIGASHIDA, Auteur ; Yoshio MINABE, Auteur ; Haruyuki KOJIMA, Auteur . - p.1216-1226. Langues : Anglais (eng) in Autism Research > 9-11 (November 2016) . - p.1216-1226 Mots-clés : autism spectrum disorder  magnetoencephalography  P1m  young children Index. décimale : PER Périodiques Résumé : The P1m component of the auditory evoked magnetic field is the earliest cortical response associated with language acquisition. However, the growth curve of the P1m component is unknown in both typically developing (TD) and atypically developing children. The aim of this study is to clarify the developmental pattern of this component when evoked by binaural human voice stimulation using child-customized magnetoencephalography. A total of 35 young TD children (32–121 months of age) and 35 children with autism spectrum disorder (ASD) (38–111 months of age) participated in this study. This is the first report to demonstrate an inverted U-shaped growth curve for the P1m dipole intensity in the left hemisphere in TD children. In addition, our results revealed a more diversified age-related distribution of auditory brain responses in 3- to 9-year-old children with ASD. These results demonstrate the diversified growth curve of the P1m component in ASD during young childhood, which is a crucial period for first language acquisition. En ligne : http://dx.doi.org/10.1002/aur.1604 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2972

Behaviour, cognition, and autism symptoms and their relationship with sleep problem severity in young children with autism spectrum disorder / Stephanie ROUSSIS in Research in Autism Spectrum Disorders, 83 (May 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 83 (May 2021) . - 101743 Titre : Behaviour, cognition, and autism symptoms and their relationship with sleep problem severity in young children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Stephanie ROUSSIS, Auteur ; Amanda L. RICHDALE, Auteur ; Terry KATZ, Auteur ; Beth A. MALOW, Auteur ; Josephine BARBARO, Auteur ; Nancy SADKA, Auteur Article en page(s) : 101743 Langues : Anglais (eng) Mots-clés : Sleep problem  Behaviour  Autism  Young children Index. décimale : PER Périodiques Résumé : Background In autism, poor sleep begins in early childhood, varies in severity and is associated with behavioural difficulties. We examined relationships between sleep and behaviour in young children with autism and no, mild/typical or severe/atypical sleep problems to determine behavioural profiles that may differentiate sleep problem severity. Method Parents of children with autism aged 2- to 5-years reported on their child’s sleep behaviour (CSHQ), including additional written descriptions of sleep behaviours. Children were then classified as good sleepers or as having mild/typical or severe/atypical sleep problems using National Sleep Foundation guidelines and current sleep literature. The three sleep groups were compared on autistic severity (ADOS), cognition (Mullen Scales of Early Leaning) and behaviour (BASC-3). Results Parents of 46 children aged 24- to 71-months participated. The severe/atypical sleep group were more likely to have multiple severe sleep difficulties. The sleep groups did not differ on autism severity or cognition. The BASC-3 withdrawal subscale differentiated severe problem sleepers from the other groups, while BASC-3 inattention differentiated problem sleepers from good sleepers. The severe/atypical sleep problem group also had more overall behaviour problems than good sleepers Conclusions Social withdrawal and multiple, severe sleep difficulties may underlie difficulties in treating poor sleep in some autistic children, suggesting that an individualised approach to treatment is needed to address severe sleep concerns. Early detection and intervention for poor sleep may reduce or prevent significant sleep and behavioural concerns continuing into later childhood. Sleep interventions that include targeting attention and withdrawal behaviours may assist in in this regard. En ligne : https://doi.org/10.1016/j.rasd.2021.101743 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4460 [article] Behaviour, cognition, and autism symptoms and their relationship with sleep problem severity in young children with autism spectrum disorder [Texte imprimé et/ou numérique] / Stephanie ROUSSIS, Auteur ; Amanda L. RICHDALE, Auteur ; Terry KATZ, Auteur ; Beth A. MALOW, Auteur ; Josephine BARBARO, Auteur ; Nancy SADKA, Auteur . - 101743. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 83 (May 2021) . - 101743 Mots-clés : Sleep problem  Behaviour  Autism  Young children Index. décimale : PER Périodiques Résumé : Background In autism, poor sleep begins in early childhood, varies in severity and is associated with behavioural difficulties. We examined relationships between sleep and behaviour in young children with autism and no, mild/typical or severe/atypical sleep problems to determine behavioural profiles that may differentiate sleep problem severity. Method Parents of children with autism aged 2- to 5-years reported on their child’s sleep behaviour (CSHQ), including additional written descriptions of sleep behaviours. Children were then classified as good sleepers or as having mild/typical or severe/atypical sleep problems using National Sleep Foundation guidelines and current sleep literature. The three sleep groups were compared on autistic severity (ADOS), cognition (Mullen Scales of Early Leaning) and behaviour (BASC-3). Results Parents of 46 children aged 24- to 71-months participated. The severe/atypical sleep group were more likely to have multiple severe sleep difficulties. The sleep groups did not differ on autism severity or cognition. The BASC-3 withdrawal subscale differentiated severe problem sleepers from the other groups, while BASC-3 inattention differentiated problem sleepers from good sleepers. The severe/atypical sleep problem group also had more overall behaviour problems than good sleepers Conclusions Social withdrawal and multiple, severe sleep difficulties may underlie difficulties in treating poor sleep in some autistic children, suggesting that an individualised approach to treatment is needed to address severe sleep concerns. Early detection and intervention for poor sleep may reduce or prevent significant sleep and behavioural concerns continuing into later childhood. Sleep interventions that include targeting attention and withdrawal behaviours may assist in in this regard. En ligne : https://doi.org/10.1016/j.rasd.2021.101743 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4460

Brief Report: Predicting Social Skills from Semantic, Syntactic, and Pragmatic Language Among Young Children with Autism Spectrum Disorder / Sarah LEVINSON in Journal of Autism and Developmental Disorders, 50-11 (November 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-11 (November 2020) . - p.4165-4175 Titre : Brief Report: Predicting Social Skills from Semantic, Syntactic, and Pragmatic Language Among Young Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Sarah LEVINSON, Auteur ; Abbey EISENHOWER, Auteur ; Hillary H. BUSH, Auteur ; Alice S. CARTER, Auteur ; Jan BLACHER, Auteur Article en page(s) : p.4165-4175 Langues : Anglais (eng) Mots-clés : Asd  Autism spectrum disorder  Grammar  Language skills  Pragmatic  Semantic  Social skills  Syntax  Vocabulary  Young children Index. décimale : PER Périodiques Résumé : The language and social skill deficits associated with autism spectrum disorder (ASD) warrant further study. Existing research has focused on the contributions of pragmatic language to social skills, with little attention to other aspects of language. We examined the associations across three language domains (semantics, syntax, and pragmatics) and their relations to parent- and teacher-rated social skills among children with ASD. When parent-reported language skills were considered simultaneously, only semantics significantly predicted children's social skills. For teacher-reported language skills, all three language domains predicted children's social skills, but none made unique contributions above and beyond one another. Further research should consider the impact of social context on language expectations and interventions targeting semantic language on children's development of social skills. En ligne : http://dx.doi.org/10.1007/s10803-020-04445-z Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4326 [article] Brief Report: Predicting Social Skills from Semantic, Syntactic, and Pragmatic Language Among Young Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Sarah LEVINSON, Auteur ; Abbey EISENHOWER, Auteur ; Hillary H. BUSH, Auteur ; Alice S. CARTER, Auteur ; Jan BLACHER, Auteur . - p.4165-4175. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-11 (November 2020) . - p.4165-4175 Mots-clés : Asd  Autism spectrum disorder  Grammar  Language skills  Pragmatic  Semantic  Social skills  Syntax  Vocabulary  Young children Index. décimale : PER Périodiques Résumé : The language and social skill deficits associated with autism spectrum disorder (ASD) warrant further study. Existing research has focused on the contributions of pragmatic language to social skills, with little attention to other aspects of language. We examined the associations across three language domains (semantics, syntax, and pragmatics) and their relations to parent- and teacher-rated social skills among children with ASD. When parent-reported language skills were considered simultaneously, only semantics significantly predicted children's social skills. For teacher-reported language skills, all three language domains predicted children's social skills, but none made unique contributions above and beyond one another. Further research should consider the impact of social context on language expectations and interventions targeting semantic language on children's development of social skills. En ligne : http://dx.doi.org/10.1007/s10803-020-04445-z Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4326

Detecting Feeding Problems in Young Children with Autism Spectrum Disorder / M. W. G. VAN DIJK in Journal of Autism and Developmental Disorders, 51-11 (November 2021)  

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Eye-Tracking in Infants and Young Children at Risk for Autism Spectrum Disorder: A Systematic Review of Visual Stimuli in Experimental Paradigms / A. M. MASTERGEORGE in Journal of Autism and Developmental Disorders, 51-8 (August 2021)  

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Interventions for Repetitive Behavior in Young Children with Autism: A Survey of Behavioral Practices / T. J. RAULSTON in Journal of Autism and Developmental Disorders, 49-8 (August 2019)  

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Maternal pre- and postnatal substance use and attachment in young children: A systematic review and meta-analysis / Noora HYYSALO in Development and Psychopathology, 34-4 (October 2022)  

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Parents Suggest Which Indicators of Progress and Outcomes Should be Measured in Young Children with Autism Spectrum Disorder / H. MCCONACHIE in Journal of Autism and Developmental Disorders, 48-4 (April 2018)  

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