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Résultat de la recherche
22 recherche sur le mot-clé 'magnetoencephalography'




Neural synchrony examined with magnetoencephalography (MEG) during eye gaze processing in autism spectrum disorders: preliminary findings / R. LAJINESS-O'NEILL in Journal of Neurodevelopmental Disorders, 6-1 (December 2014)
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[article]
Titre : Neural synchrony examined with magnetoencephalography (MEG) during eye gaze processing in autism spectrum disorders: preliminary findings Type de document : Texte imprimé et/ou numérique Auteurs : R. LAJINESS-O'NEILL, Auteur ; A. E. RICHARD, Auteur ; J. E. MORAN, Auteur ; A. OLSZEWSKI, Auteur ; L. PAWLUK, Auteur ; D. JACOBSON, Auteur ; A. MANSOUR, Auteur ; K. VOGT, Auteur ; L. A. ERDODI, Auteur ; A. M. MOORE, Auteur ; S. M. BOWYER, Auteur Article en page(s) : p.15 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Coherence Eye gaze Magnetoencephalography Neural synchrony Social cognition Index. décimale : PER Périodiques Résumé : BACKGROUND: Gaze processing deficits are a seminal, early, and enduring behavioral deficit in autism spectrum disorder (ASD); however, a comprehensive characterization of the neural processes mediating abnormal gaze processing in ASD has yet to be conducted. METHODS: This study investigated whole-brain patterns of neural synchrony during passive viewing of direct and averted eye gaze in ASD adolescents and young adults (M Age = 16.6) compared to neurotypicals (NT) (M Age = 17.5) while undergoing magnetoencephalography. Coherence between each pair of 54 brain regions within each of three frequency bands (low frequency (0 to 15 Hz), beta (15 to 30 Hz), and low gamma (30 to 45 Hz)) was calculated. RESULTS: Significantly higher coherence and synchronization in posterior brain regions (temporo-parietal-occipital) across all frequencies was evident in ASD, particularly within the low 0 to 15 Hz frequency range. Higher coherence in fronto-temporo-parietal regions was noted in NT. A significantly higher number of low frequency cross-hemispheric synchronous connections and a near absence of right intra-hemispheric coherence in the beta frequency band were noted in ASD. Significantly higher low frequency coherent activity in bilateral temporo-parieto-occipital cortical regions and higher gamma band coherence in right temporo-parieto-occipital brain regions during averted gaze was related to more severe symptomology as reported on the Autism Diagnostic Interview-Revised (ADI-R). CONCLUSIONS: The preliminary results suggest a pattern of aberrant connectivity that includes higher low frequency synchronization in posterior cortical regions, lack of long-range right hemispheric beta and gamma coherence, and decreased coherence in fronto-temporo-parietal regions necessary for orienting to shifts in eye gaze in ASD; a critical behavior essential for social communication. En ligne : http://dx.doi.org/10.1186/1866-1955-6-15 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=346
in Journal of Neurodevelopmental Disorders > 6-1 (December 2014) . - p.15[article] Neural synchrony examined with magnetoencephalography (MEG) during eye gaze processing in autism spectrum disorders: preliminary findings [Texte imprimé et/ou numérique] / R. LAJINESS-O'NEILL, Auteur ; A. E. RICHARD, Auteur ; J. E. MORAN, Auteur ; A. OLSZEWSKI, Auteur ; L. PAWLUK, Auteur ; D. JACOBSON, Auteur ; A. MANSOUR, Auteur ; K. VOGT, Auteur ; L. A. ERDODI, Auteur ; A. M. MOORE, Auteur ; S. M. BOWYER, Auteur . - p.15.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 6-1 (December 2014) . - p.15
Mots-clés : Autism spectrum disorder Coherence Eye gaze Magnetoencephalography Neural synchrony Social cognition Index. décimale : PER Périodiques Résumé : BACKGROUND: Gaze processing deficits are a seminal, early, and enduring behavioral deficit in autism spectrum disorder (ASD); however, a comprehensive characterization of the neural processes mediating abnormal gaze processing in ASD has yet to be conducted. METHODS: This study investigated whole-brain patterns of neural synchrony during passive viewing of direct and averted eye gaze in ASD adolescents and young adults (M Age = 16.6) compared to neurotypicals (NT) (M Age = 17.5) while undergoing magnetoencephalography. Coherence between each pair of 54 brain regions within each of three frequency bands (low frequency (0 to 15 Hz), beta (15 to 30 Hz), and low gamma (30 to 45 Hz)) was calculated. RESULTS: Significantly higher coherence and synchronization in posterior brain regions (temporo-parietal-occipital) across all frequencies was evident in ASD, particularly within the low 0 to 15 Hz frequency range. Higher coherence in fronto-temporo-parietal regions was noted in NT. A significantly higher number of low frequency cross-hemispheric synchronous connections and a near absence of right intra-hemispheric coherence in the beta frequency band were noted in ASD. Significantly higher low frequency coherent activity in bilateral temporo-parieto-occipital cortical regions and higher gamma band coherence in right temporo-parieto-occipital brain regions during averted gaze was related to more severe symptomology as reported on the Autism Diagnostic Interview-Revised (ADI-R). CONCLUSIONS: The preliminary results suggest a pattern of aberrant connectivity that includes higher low frequency synchronization in posterior cortical regions, lack of long-range right hemispheric beta and gamma coherence, and decreased coherence in fronto-temporo-parietal regions necessary for orienting to shifts in eye gaze in ASD; a critical behavior essential for social communication. En ligne : http://dx.doi.org/10.1186/1866-1955-6-15 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=346 Patterns of altered neural synchrony in the default mode network in autism spectrum disorder revealed with magnetoencephalography (MEG): Relationship to clinical symptomatology / R. LAJINESS-O'NEILL in Autism Research, 11-3 (March 2018)
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Titre : Patterns of altered neural synchrony in the default mode network in autism spectrum disorder revealed with magnetoencephalography (MEG): Relationship to clinical symptomatology Type de document : Texte imprimé et/ou numérique Auteurs : R. LAJINESS-O'NEILL, Auteur ; J. R. BRENNAN, Auteur ; J. E. MORAN, Auteur ; A. E. RICHARD, Auteur ; A. M. FLORES, Auteur ; C. SWICK, Auteur ; R. GOODCASE, Auteur ; T. ANDERSEN, Auteur ; K. MCFARLANE, Auteur ; K. RUSINIAK, Auteur ; I. KOVELMAN, Auteur ; N. WAGLEY, Auteur ; M. UGOLINI, Auteur ; Jordan ALBRIGHT, Auteur ; S. M. BOWYER, Auteur Article en page(s) : p.434-449 Langues : Anglais (eng) Mots-clés : autism spectrum disorder coherence default mode network gamma magnetoencephalography salience network synchrony Index. décimale : PER Périodiques Résumé : Disrupted neural synchrony may be a primary electrophysiological abnormality in autism spectrum disorders (ASD), altering communication between discrete brain regions and contributing to abnormalities in patterns of connectivity within identified neural networks. Studies exploring brain dynamics to comprehensively characterize and link connectivity to large-scale cortical networks and clinical symptoms are lagging considerably. Patterns of neural coherence within the Default Mode Network (DMN) and Salience Network (SN) during resting state were investigated in 12 children with ASD (MAge = 9.2) and 13 age and gender-matched neurotypicals (NT) (MAge = 9.3) with magnetoencephalography. Coherence between 231 brain region pairs within four frequency bands (theta (4-7 Hz), alpha, (8-12 Hz), beta (13-30 Hz), and gamma (30-80 Hz)) was calculated. Relationships between neural coherence and social functioning were examined. ASD was characterized by lower synchronization across all frequencies, reaching clinical significance in the gamma band. Lower gamma synchrony between fronto-temporo-parietal regions was observed, partially consistent with diminished default mode network (DMN) connectivity. Lower gamma coherence in ASD was evident in cross-hemispheric connections between: angular with inferior/middle frontal; middle temporal with middle/inferior frontal; and within right-hemispheric connections between angular, middle temporal, and inferior/middle frontal cortices. Lower gamma coherence between left angular and left superior frontal, right inferior/middle frontal, and right precuneus and between right angular and inferior/middle frontal cortices was related to lower social/social-communication functioning. Results suggest a pattern of lower gamma band coherence in a subset of regions within the DMN in ASD (angular and middle temporal cortical areas) related to lower social/social-communicative functioning. Autism Res 2018, 11: 434-449. (c) 2017 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Communication between different areas of the brain was observed in children with ASD and neurotypical children while awake, but not working on a task. Magnetoencephalography was used to measure tiny magnetic fields naturally generated via brain activity. The brains of children with ASD showed less communication between areas that are important for social information processing compared to the brains of neurotypical children. The amount of communication between these areas was associated with social and social communication difficulties. En ligne : http://dx.doi.org/10.1002/aur.1908 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=352
in Autism Research > 11-3 (March 2018) . - p.434-449[article] Patterns of altered neural synchrony in the default mode network in autism spectrum disorder revealed with magnetoencephalography (MEG): Relationship to clinical symptomatology [Texte imprimé et/ou numérique] / R. LAJINESS-O'NEILL, Auteur ; J. R. BRENNAN, Auteur ; J. E. MORAN, Auteur ; A. E. RICHARD, Auteur ; A. M. FLORES, Auteur ; C. SWICK, Auteur ; R. GOODCASE, Auteur ; T. ANDERSEN, Auteur ; K. MCFARLANE, Auteur ; K. RUSINIAK, Auteur ; I. KOVELMAN, Auteur ; N. WAGLEY, Auteur ; M. UGOLINI, Auteur ; Jordan ALBRIGHT, Auteur ; S. M. BOWYER, Auteur . - p.434-449.
Langues : Anglais (eng)
in Autism Research > 11-3 (March 2018) . - p.434-449
Mots-clés : autism spectrum disorder coherence default mode network gamma magnetoencephalography salience network synchrony Index. décimale : PER Périodiques Résumé : Disrupted neural synchrony may be a primary electrophysiological abnormality in autism spectrum disorders (ASD), altering communication between discrete brain regions and contributing to abnormalities in patterns of connectivity within identified neural networks. Studies exploring brain dynamics to comprehensively characterize and link connectivity to large-scale cortical networks and clinical symptoms are lagging considerably. Patterns of neural coherence within the Default Mode Network (DMN) and Salience Network (SN) during resting state were investigated in 12 children with ASD (MAge = 9.2) and 13 age and gender-matched neurotypicals (NT) (MAge = 9.3) with magnetoencephalography. Coherence between 231 brain region pairs within four frequency bands (theta (4-7 Hz), alpha, (8-12 Hz), beta (13-30 Hz), and gamma (30-80 Hz)) was calculated. Relationships between neural coherence and social functioning were examined. ASD was characterized by lower synchronization across all frequencies, reaching clinical significance in the gamma band. Lower gamma synchrony between fronto-temporo-parietal regions was observed, partially consistent with diminished default mode network (DMN) connectivity. Lower gamma coherence in ASD was evident in cross-hemispheric connections between: angular with inferior/middle frontal; middle temporal with middle/inferior frontal; and within right-hemispheric connections between angular, middle temporal, and inferior/middle frontal cortices. Lower gamma coherence between left angular and left superior frontal, right inferior/middle frontal, and right precuneus and between right angular and inferior/middle frontal cortices was related to lower social/social-communication functioning. Results suggest a pattern of lower gamma band coherence in a subset of regions within the DMN in ASD (angular and middle temporal cortical areas) related to lower social/social-communicative functioning. Autism Res 2018, 11: 434-449. (c) 2017 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Communication between different areas of the brain was observed in children with ASD and neurotypical children while awake, but not working on a task. Magnetoencephalography was used to measure tiny magnetic fields naturally generated via brain activity. The brains of children with ASD showed less communication between areas that are important for social information processing compared to the brains of neurotypical children. The amount of communication between these areas was associated with social and social communication difficulties. En ligne : http://dx.doi.org/10.1002/aur.1908 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=352 Abnormal auditory mismatch fields are associated with communication impairment in both verbal and minimally verbal/nonverbal children who have autism spectrum disorder / J. MATSUZAKI in Autism Research, 12-8 (August 2019)
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Titre : Abnormal auditory mismatch fields are associated with communication impairment in both verbal and minimally verbal/nonverbal children who have autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : J. MATSUZAKI, Auteur ; E. S. KUSCHNER, Auteur ; Lisa BLASKEY, Auteur ; Luke BLOY, Auteur ; M. KIM, Auteur ; M. KU, Auteur ; J. C. EDGAR, Auteur ; D. EMBICK, Auteur ; T. P. L. ROBERTS, Auteur Article en page(s) : p.1225-1235 Langues : Anglais (eng) Mots-clés : autism spectrum disorder language and communication skill magnetoencephalography minimally verbal/non-verbal children vowel mismatch fields Index. décimale : PER Périodiques Résumé : Abnormal auditory discrimination neural processes, indexed by mismatch fields (MMFs) recorded by magnetoencephalography (MEG), have been reported in verbal children with ASD. Association with clinical measures indicates that delayed MMF components are associated with poorer language and communication performance. At present, little is known about neural correlates of language and communication skills in extremely language impaired (minimally-verbal/non-verbal) children who have ASD: ASD-MVNV. It is hypothesized that MMF delays observed in language-impaired but nonetheless verbal children with ASD will be exacerbated in ASD-MVNV. The present study investigated this hypothesis, examining MMF responses bilaterally during an auditory oddball paradigm with vowel stimuli in ASD-MVNV, in a verbal ASD cohort without cognitive impairment and in typically developing (TD) children. The verbal ASD cohort without cognitive impairment was split into those demonstrating considerable language impairment (CELF core language index <85; "ASD-LI") versus those with less or no language impairment (CELF CLI >85; "ASD-V"). Eighty-four participants (8-12 years) were included in final analysis: ASD-MVNV: n = 9, 9.67 +/- 1.41 years, ASD: n = 48, (ASD-V: n = 27, 10.55 +/- 1.21 years, ASD-LI: n = 21, 10.67 +/- 1.20 years) and TD: n = 27, 10.14 +/- 1.38 years. Delayed MMF latencies were found bilaterally in ASD-MVNV compared to verbal ASD (both ASD-V and ASD-LI) and TD children. Delayed MMF responses were associated with diminished language and communication skills. Furthermore, whereas the TD children showed leftward lateralization of MMF amplitude, ASD-MVNV and verbal ASD (ASD-V and ASD-LI) showed abnormal rightward lateralization. Findings suggest delayed auditory discrimination processes and abnormal rightward laterality as objective markers of language/communication skills in both verbal and MVNV children who have ASD. Autism Res 2019, 12: 1225-1235. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Brain imaging showed abnormal auditory discrimination processes in minimally-verbal/non-verbal children (MVNV) who have autism spectrum disorder (ASD). Delays in auditory discrimination were associated with impaired language and communication skills. Findings suggest these auditory neural measures may be objective markers of language and communication skills in both verbal and, previously-understudied, MVNV children who have ASD. En ligne : http://dx.doi.org/10.1002/aur.2136 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405
in Autism Research > 12-8 (August 2019) . - p.1225-1235[article] Abnormal auditory mismatch fields are associated with communication impairment in both verbal and minimally verbal/nonverbal children who have autism spectrum disorder [Texte imprimé et/ou numérique] / J. MATSUZAKI, Auteur ; E. S. KUSCHNER, Auteur ; Lisa BLASKEY, Auteur ; Luke BLOY, Auteur ; M. KIM, Auteur ; M. KU, Auteur ; J. C. EDGAR, Auteur ; D. EMBICK, Auteur ; T. P. L. ROBERTS, Auteur . - p.1225-1235.
Langues : Anglais (eng)
in Autism Research > 12-8 (August 2019) . - p.1225-1235
Mots-clés : autism spectrum disorder language and communication skill magnetoencephalography minimally verbal/non-verbal children vowel mismatch fields Index. décimale : PER Périodiques Résumé : Abnormal auditory discrimination neural processes, indexed by mismatch fields (MMFs) recorded by magnetoencephalography (MEG), have been reported in verbal children with ASD. Association with clinical measures indicates that delayed MMF components are associated with poorer language and communication performance. At present, little is known about neural correlates of language and communication skills in extremely language impaired (minimally-verbal/non-verbal) children who have ASD: ASD-MVNV. It is hypothesized that MMF delays observed in language-impaired but nonetheless verbal children with ASD will be exacerbated in ASD-MVNV. The present study investigated this hypothesis, examining MMF responses bilaterally during an auditory oddball paradigm with vowel stimuli in ASD-MVNV, in a verbal ASD cohort without cognitive impairment and in typically developing (TD) children. The verbal ASD cohort without cognitive impairment was split into those demonstrating considerable language impairment (CELF core language index <85; "ASD-LI") versus those with less or no language impairment (CELF CLI >85; "ASD-V"). Eighty-four participants (8-12 years) were included in final analysis: ASD-MVNV: n = 9, 9.67 +/- 1.41 years, ASD: n = 48, (ASD-V: n = 27, 10.55 +/- 1.21 years, ASD-LI: n = 21, 10.67 +/- 1.20 years) and TD: n = 27, 10.14 +/- 1.38 years. Delayed MMF latencies were found bilaterally in ASD-MVNV compared to verbal ASD (both ASD-V and ASD-LI) and TD children. Delayed MMF responses were associated with diminished language and communication skills. Furthermore, whereas the TD children showed leftward lateralization of MMF amplitude, ASD-MVNV and verbal ASD (ASD-V and ASD-LI) showed abnormal rightward lateralization. Findings suggest delayed auditory discrimination processes and abnormal rightward laterality as objective markers of language/communication skills in both verbal and MVNV children who have ASD. Autism Res 2019, 12: 1225-1235. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Brain imaging showed abnormal auditory discrimination processes in minimally-verbal/non-verbal children (MVNV) who have autism spectrum disorder (ASD). Delays in auditory discrimination were associated with impaired language and communication skills. Findings suggest these auditory neural measures may be objective markers of language and communication skills in both verbal and, previously-understudied, MVNV children who have ASD. En ligne : http://dx.doi.org/10.1002/aur.2136 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405 Abnormal Brain Dynamics Underlie Speech Production in Children with Autism Spectrum Disorder / Elizabeth W. PANG in Autism Research, 9-2 (February 2016)
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Titre : Abnormal Brain Dynamics Underlie Speech Production in Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Elizabeth W. PANG, Auteur ; Tatiana VALICA, Auteur ; Matt J. MACDONALD, Auteur ; Margot J. TAYLOR, Auteur ; Jessica BRIAN, Auteur ; Jason P. LERCH, Auteur ; Evdokia ANAGNOSTOU, Auteur Article en page(s) : p.249-261 Langues : Anglais (eng) Mots-clés : magnetoencephalography oromotor control phoneme production phonemic sequencing autism spectrum disorder Index. décimale : PER Périodiques Résumé : A large proportion of children with autism spectrum disorder (ASD) have speech and/or language difficulties. While a number of structural and functional neuroimaging methods have been used to explore the brain differences in ASD with regards to speech and language comprehension and production, the neurobiology of basic speech function in ASD has not been examined. Magnetoencephalography (MEG) is a neuroimaging modality with high spatial and temporal resolution that can be applied to the examination of brain dynamics underlying speech as it can capture the fast responses fundamental to this function. We acquired MEG from 21 children with high-functioning autism (mean age: 11.43 years) and 21 age- and sex-matched controls as they performed a simple oromotor task, a phoneme production task and a phonemic sequencing task. Results showed significant differences in activation magnitude and peak latencies in primary motor cortex (Brodmann Area 4), motor planning areas (BA 6), temporal sequencing and sensorimotor integration areas (BA 22/13) and executive control areas (BA 9). Our findings of significant functional brain differences between these two groups on these simple oromotor and phonemic tasks suggest that these deficits may be foundational and could underlie the language deficits seen in ASD. En ligne : http://dx.doi.org/10.1002/aur.1526 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=282
in Autism Research > 9-2 (February 2016) . - p.249-261[article] Abnormal Brain Dynamics Underlie Speech Production in Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Elizabeth W. PANG, Auteur ; Tatiana VALICA, Auteur ; Matt J. MACDONALD, Auteur ; Margot J. TAYLOR, Auteur ; Jessica BRIAN, Auteur ; Jason P. LERCH, Auteur ; Evdokia ANAGNOSTOU, Auteur . - p.249-261.
Langues : Anglais (eng)
in Autism Research > 9-2 (February 2016) . - p.249-261
Mots-clés : magnetoencephalography oromotor control phoneme production phonemic sequencing autism spectrum disorder Index. décimale : PER Périodiques Résumé : A large proportion of children with autism spectrum disorder (ASD) have speech and/or language difficulties. While a number of structural and functional neuroimaging methods have been used to explore the brain differences in ASD with regards to speech and language comprehension and production, the neurobiology of basic speech function in ASD has not been examined. Magnetoencephalography (MEG) is a neuroimaging modality with high spatial and temporal resolution that can be applied to the examination of brain dynamics underlying speech as it can capture the fast responses fundamental to this function. We acquired MEG from 21 children with high-functioning autism (mean age: 11.43 years) and 21 age- and sex-matched controls as they performed a simple oromotor task, a phoneme production task and a phonemic sequencing task. Results showed significant differences in activation magnitude and peak latencies in primary motor cortex (Brodmann Area 4), motor planning areas (BA 6), temporal sequencing and sensorimotor integration areas (BA 22/13) and executive control areas (BA 9). Our findings of significant functional brain differences between these two groups on these simple oromotor and phonemic tasks suggest that these deficits may be foundational and could underlie the language deficits seen in ASD. En ligne : http://dx.doi.org/10.1002/aur.1526 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=282 Atypical development of the central auditory system in young children with Autism spectrum disorder / Yuko YOSHIMURA in Autism Research, 9-11 (November 2016)
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Titre : Atypical development of the central auditory system in young children with Autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Yuko YOSHIMURA, Auteur ; Mitsuru KIKUCHI, Auteur ; Hirotoshi HIRAISHI, Auteur ; Chiaki HASEGAWA, Auteur ; Tetsuya TAKAHASHI, Auteur ; Gerard B. REMIJN, Auteur ; Manabu OI, Auteur ; Toshio MUNESUE, Auteur ; Haruhiro HIGASHIDA, Auteur ; Yoshio MINABE, Auteur ; Haruyuki KOJIMA, Auteur Article en page(s) : p.1216-1226 Langues : Anglais (eng) Mots-clés : autism spectrum disorder magnetoencephalography P1m young children Index. décimale : PER Périodiques Résumé : The P1m component of the auditory evoked magnetic field is the earliest cortical response associated with language acquisition. However, the growth curve of the P1m component is unknown in both typically developing (TD) and atypically developing children. The aim of this study is to clarify the developmental pattern of this component when evoked by binaural human voice stimulation using child-customized magnetoencephalography. A total of 35 young TD children (32–121 months of age) and 35 children with autism spectrum disorder (ASD) (38–111 months of age) participated in this study. This is the first report to demonstrate an inverted U-shaped growth curve for the P1m dipole intensity in the left hemisphere in TD children. In addition, our results revealed a more diversified age-related distribution of auditory brain responses in 3- to 9-year-old children with ASD. These results demonstrate the diversified growth curve of the P1m component in ASD during young childhood, which is a crucial period for first language acquisition. En ligne : http://dx.doi.org/10.1002/aur.1604 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297
in Autism Research > 9-11 (November 2016) . - p.1216-1226[article] Atypical development of the central auditory system in young children with Autism spectrum disorder [Texte imprimé et/ou numérique] / Yuko YOSHIMURA, Auteur ; Mitsuru KIKUCHI, Auteur ; Hirotoshi HIRAISHI, Auteur ; Chiaki HASEGAWA, Auteur ; Tetsuya TAKAHASHI, Auteur ; Gerard B. REMIJN, Auteur ; Manabu OI, Auteur ; Toshio MUNESUE, Auteur ; Haruhiro HIGASHIDA, Auteur ; Yoshio MINABE, Auteur ; Haruyuki KOJIMA, Auteur . - p.1216-1226.
Langues : Anglais (eng)
in Autism Research > 9-11 (November 2016) . - p.1216-1226
Mots-clés : autism spectrum disorder magnetoencephalography P1m young children Index. décimale : PER Périodiques Résumé : The P1m component of the auditory evoked magnetic field is the earliest cortical response associated with language acquisition. However, the growth curve of the P1m component is unknown in both typically developing (TD) and atypically developing children. The aim of this study is to clarify the developmental pattern of this component when evoked by binaural human voice stimulation using child-customized magnetoencephalography. A total of 35 young TD children (32–121 months of age) and 35 children with autism spectrum disorder (ASD) (38–111 months of age) participated in this study. This is the first report to demonstrate an inverted U-shaped growth curve for the P1m dipole intensity in the left hemisphere in TD children. In addition, our results revealed a more diversified age-related distribution of auditory brain responses in 3- to 9-year-old children with ASD. These results demonstrate the diversified growth curve of the P1m component in ASD during young childhood, which is a crucial period for first language acquisition. En ligne : http://dx.doi.org/10.1002/aur.1604 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297 Autism Traits in Individuals with Agenesis of the Corpus Callosum / Yolanda C. LAU in Journal of Autism and Developmental Disorders, 43-5 (May 2013)
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PermalinkChildren With Autism Show Reduced Somatosensory Response: An MEG Study / Elysa J. MARCO in Autism Research, 5-5 (October 2012)
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PermalinkChildren with autism spectrum disorder show altered functional connectivity and abnormal maturation trajectories in response to inverted faces / F. MAMASHLI in Autism Research, 14-6 (June 2021)
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PermalinkDelayed M50/M100 evoked response component latency in minimally verbal/nonverbal children who have autism spectrum disorder / T. P. L. ROBERTS in Molecular Autism, 10 (2019)
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PermalinkEnhanced Access to Early Visual Processing of Perceptual Simultaneity in Autism Spectrum Disorders / Christine M. FALTER in Journal of Autism and Developmental Disorders, 43-8 (August 2013)
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