Pubmed du 20/09/14

Pubmed du jour

2014-09-20 12:03:50

1. Bishop SL, Farmer C, Thurm A. {{Measurement of Nonverbal IQ in Autism Spectrum Disorder: Scores in Young Adulthood Compared to Early Childhood}}. {J Autism Dev Disord};2014 (Sep 20)
Nonverbal IQ (NVIQ) was examined in 84 individuals with autism spectrum disorder (ASD) followed from age 2 to 19. Most adults who scored in the range of intellectual disability also received scores below 70 as children, and the majority of adults with scores in the average range had scored in this range by age 3. However, within the lower ranges of ability, actual scores declined from age 2 to 19, likely due in part to limitations of appropriate tests. Use of Vineland-II daily living skills scores in place of NVIQ did not statistically improve the correspondence between age 2 and age 19 scores. Clinicians and researchers should use caution when making comparisons based on exact scores or specific ability ranges within or across individuals with ASD of different ages.

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2. Nadeau JM, Arnold EB, Keene AC, Collier AB, Lewin AB, Murphy TK, Storch EA. {{Frequency and Clinical Correlates of Sleep-Related Problems Among Anxious Youth with Autism Spectrum Disorders}}. {Child Psychiatry Hum Dev};2014 (Sep 20)
Sleep-related problems (SRPs) are common and problematic among anxious youth but have not been investigated in anxious youth with autism spectrum disorder (ASD). Participants were 102 youth (ages 7-16 years) with ASD and comorbid anxiety. Youth and their primary caregiver were administered the Pediatric Anxiety Rating Scale. Parents completed the Multidimensional Anxiety Scale for Children-Parent (MASC-P) Report, Social Responsiveness Scale, and the Child Behavior Checklist (CBCL). A measure of SRPs was created from items from the CBCL and MASC-P. Results suggest SRPs were relatively common among youth with ASD and comorbid anxiety. The number of SRPs endorsed directly associated with parent ratings of social deficits, internalizing and externalizing symptoms, and anxiety symptoms, as well as with clinician-rated anxiety symptoms. Parent-rated internalizing symptoms predicted frequency of SRPs over and above social deficits, externalizing symptoms, and parent- and clinician-rated anxiety symptoms. A subset of 40 participants who completed family-based cognitive-behavioral therapy (CBT) experienced reduced SRPs following treatment. Implications, study limitations, and recommendations for future research are discussed.

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3. Rescorla L, Kim YA, Oh KJ. {{Screening for ASD with the Korean CBCL/1(1/2)-5}}. {J Autism Dev Disord};2014 (Sep 20)
To test the Child Behavior Checklist’s (CBCL/1(1/2)-5) ability to screen for autism spectrum disorders (ASD), we studied Korean preschoolers: 46 with ASD, 111 with developmental delay (DD), 71 with other psychiatric disorders (OPD), and 228 non-referred (NR). The ASD group scored significantly higher than the other groups on the Withdrawn and DSM-Pervasive Developmental Problems (DSM-PDP) scales as well as attaining higher scores (p < .001) on seven items reflecting ASD. With a T >/= 65 cutpoint on the DSM-PDP scale, sensitivity was 80 % for identifying ASD relative to the other three groups, but specificity varied across groups: NR = 87 %, OPD = 55 %, DD = 60 %, replicating in a non-Western sample results from previous studies. Results suggested that the CBCL/1(1/2)-5 performs best in Level 1 screening, namely differentiating children with ASD from children in the general population.

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4. Vivanti G. {{The Importance of Distinguishing Propensity Versus Ability to Imitate in ASD Research and Early Detection}}. {J Autism Dev Disord};2014 (Sep 20)
Imitation abnormalities are often documented in young children with Autism Spectrum Disorder (ASD), however the relevance of imitation to early development and early detection of ASD remains unclear. Recent studies that investigated whether imitation at 12 months distinguishes children who will subsequently receive an ASD diagnosis from other high-risk groups have reported conflicting results. The purpose of this note is to provide a framework to interpret these conflicting findings, which is based on the often-overlooked distinction between the propensity to imitate and the ability to imitate. We argue that this distinction can critically inform understanding of early imitative behaviour in ASD and the development of early detection procedures.

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