Assessment and Treatment in Autism Spectrum Disorders: A Focus on Genetics and Psychiatry / Merlin G. BUTLER in Autism Research and Treatment, (March 2012)  

Public ISBD [article]  inAutism Research and Treatment > (March 2012) . - 11 p. Titre : Assessment and Treatment in Autism Spectrum Disorders: A Focus on Genetics and Psychiatry Type de document : texte imprimé Auteurs : Merlin G. BUTLER, Auteur ; Erin L. YOUNGS, Auteur ; Jennifer L. ROBERTS, Auteur ; Jessica A. HELLINGS, Auteur Année de publication : 2012 Article en page(s) : 11 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASDs) are neurobehavioral disorders characterized by abnormalities in three behavioral domains including social interaction, impaired communication, and repetitive stereotypic behaviors. ASD affects approximately 1% of children and is on the rise with significant genetic mechanisms underlying these disorders. We review the current understanding of the role of genetic and metabolic factors contributing to ASD with the use of new genetic technology. Fifty percent is diagnosed with chromosomal abnormalities, small DNA deletions/duplications, single-gene conditions, or metabolic disturbances. Genetic evaluation is discussed along with psychiatric treatment and approaches for selection of medication to treat associated challenging behaviors or comorbidities seen in ASD. We emphasize the importance of prioritizing treatment based on target symptom clusters and in what order for individuals with ASD, as the treatment may vary from patient to patient. En ligne : http://dx.doi.org/10.1155/2012/242537 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178 [article] Assessment and Treatment in Autism Spectrum Disorders: A Focus on Genetics and Psychiatry [texte imprimé] / Merlin G. BUTLER, Auteur ; Erin L. YOUNGS, Auteur ; Jennifer L. ROBERTS, Auteur ; Jessica A. HELLINGS, Auteur . - 2012 . - 11 p. Langues : Anglais (eng) in Autism Research and Treatment > (March 2012) . - 11 p. Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASDs) are neurobehavioral disorders characterized by abnormalities in three behavioral domains including social interaction, impaired communication, and repetitive stereotypic behaviors. ASD affects approximately 1% of children and is on the rise with significant genetic mechanisms underlying these disorders. We review the current understanding of the role of genetic and metabolic factors contributing to ASD with the use of new genetic technology. Fifty percent is diagnosed with chromosomal abnormalities, small DNA deletions/duplications, single-gene conditions, or metabolic disturbances. Genetic evaluation is discussed along with psychiatric treatment and approaches for selection of medication to treat associated challenging behaviors or comorbidities seen in ASD. We emphasize the importance of prioritizing treatment based on target symptom clusters and in what order for individuals with ASD, as the treatment may vary from patient to patient. En ligne : http://dx.doi.org/10.1155/2012/242537 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178

Incorporation of Telepsychiatry for Patients with Developmental Disorders into Routine Clinical Practice-A Survey of Specialty Clinics Adapting to Telepsychiatry During the COVID-19 Pandemic / Shikha VERMA in Journal of Autism and Developmental Disorders, 52-12 (December 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-12 (December 2022) . - p.5280-5284 Titre : Incorporation of Telepsychiatry for Patients with Developmental Disorders into Routine Clinical Practice-A Survey of Specialty Clinics Adapting to Telepsychiatry During the COVID-19 Pandemic Type de document : texte imprimé Auteurs : Shikha VERMA, Auteur ; Pankhuree VANDANA, Auteur ; Takahiro SODA, Auteur ; Kathleen A. KOTH, Auteur ; Patricia AGUAYO, Auteur ; Rebecca C. SHAFFER, Auteur ; Jessica A. HELLINGS, Auteur ; Rebecca A. MUHLE, Auteur Année de publication : 2022 Article en page(s) : p.5280-5284 Langues : Anglais (eng) Mots-clés : Child  Humans  Pandemics  covid-19  Psychiatry  Autism Spectrum Disorder/therapy  Developmental Disabilities/therapy  Telemedicine  Communicable Disease Control  Autism spectrum disorder  Clinical care  Developmental Disabilities  Telepsychiatry Index. décimale : PER Périodiques Résumé : In 2020, a nationwide shift to telepsychiatry occurred in the wake of the Coronavirus Disease 2019 (COVID-19) pandemic and lockdowns. To assess the rates of telepsychiatry appointment attendance pre- and post-lockdown, we conducted a national, multi-site survey of appointments in 2020 compared to a similar time period in 2019, at outpatient child psychiatry clinics that specialize in the treatment of patients with Autism Spectrum Disorder (ASD) and/or Developmental Disabilities (DD). ASD/DD clinics rapidly shifted to telepsychiatry, returning to pre-pandemic appointment numbers and completion rates within months. We advocate for the continued funding of this care model, discuss the substantial benefits physicians, patients and families have found in using telepsychiatry, and suggest ways to improve future access for ASD/DD telepsychiatry. En ligne : http://dx.doi.org/10.1007/s10803-022-05593-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=489 [article] Incorporation of Telepsychiatry for Patients with Developmental Disorders into Routine Clinical Practice-A Survey of Specialty Clinics Adapting to Telepsychiatry During the COVID-19 Pandemic [texte imprimé] / Shikha VERMA, Auteur ; Pankhuree VANDANA, Auteur ; Takahiro SODA, Auteur ; Kathleen A. KOTH, Auteur ; Patricia AGUAYO, Auteur ; Rebecca C. SHAFFER, Auteur ; Jessica A. HELLINGS, Auteur ; Rebecca A. MUHLE, Auteur . - 2022 . - p.5280-5284. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-12 (December 2022) . - p.5280-5284 Mots-clés : Child  Humans  Pandemics  covid-19  Psychiatry  Autism Spectrum Disorder/therapy  Developmental Disabilities/therapy  Telemedicine  Communicable Disease Control  Autism spectrum disorder  Clinical care  Developmental Disabilities  Telepsychiatry Index. décimale : PER Périodiques Résumé : In 2020, a nationwide shift to telepsychiatry occurred in the wake of the Coronavirus Disease 2019 (COVID-19) pandemic and lockdowns. To assess the rates of telepsychiatry appointment attendance pre- and post-lockdown, we conducted a national, multi-site survey of appointments in 2020 compared to a similar time period in 2019, at outpatient child psychiatry clinics that specialize in the treatment of patients with Autism Spectrum Disorder (ASD) and/or Developmental Disabilities (DD). ASD/DD clinics rapidly shifted to telepsychiatry, returning to pre-pandemic appointment numbers and completion rates within months. We advocate for the continued funding of this care model, discuss the substantial benefits physicians, patients and families have found in using telepsychiatry, and suggest ways to improve future access for ASD/DD telepsychiatry. En ligne : http://dx.doi.org/10.1007/s10803-022-05593-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=489

Loxapine for Reversal of Antipsychotic-Induced Metabolic Disturbances: A Chart Review / Seema JAIN in Journal of Autism and Developmental Disorders, 46-4 (April 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-4 (April 2016) . - p.1344-1353 Titre : Loxapine for Reversal of Antipsychotic-Induced Metabolic Disturbances: A Chart Review Type de document : texte imprimé Auteurs : Seema JAIN, Auteur ; Rebecca R. ANDRIDGE, Auteur ; Jessica A. HELLINGS, Auteur Article en page(s) : p.1344-1353 Langues : Anglais (eng) Mots-clés : Loxapine  Metabolic side effects  Autism spectrum disorder  Atypical antipsychotics Index. décimale : PER Périodiques Résumé : Loxapine substitution is a promising option for patients with autism spectrum disorder (ASD) who develop antipsychotic-induced metabolic illness. We performed a chart review of 15 adolescents and adults meeting DSM-IV-TR criteria for ASD, all with antipsychotic-associated weight gain, who received low dose loxapine in an attempt to taper or discontinue the weight gain-associated antipsychotic. Mean weight loss was −5.7 kg, mean BMI reduction was −1.9, and mean triglyceride reduction was −33.7 mg/dl. At chart review, 14 of 15 subjects were rated 2 (Much Improved) or 1 (Very Much Improved) on the Clinical Global Impressions-Improvement scale (CGI-I). Low dose loxapine addition in most cases enabled taper of offending antipsychotics, significantly reversed drug-induced metabolic disturbances and improved irritability. En ligne : http://dx.doi.org/10.1007/s10803-015-2675-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=284 [article] Loxapine for Reversal of Antipsychotic-Induced Metabolic Disturbances: A Chart Review [texte imprimé] / Seema JAIN, Auteur ; Rebecca R. ANDRIDGE, Auteur ; Jessica A. HELLINGS, Auteur . - p.1344-1353. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-4 (April 2016) . - p.1344-1353 Mots-clés : Loxapine  Metabolic side effects  Autism spectrum disorder  Atypical antipsychotics Index. décimale : PER Périodiques Résumé : Loxapine substitution is a promising option for patients with autism spectrum disorder (ASD) who develop antipsychotic-induced metabolic illness. We performed a chart review of 15 adolescents and adults meeting DSM-IV-TR criteria for ASD, all with antipsychotic-associated weight gain, who received low dose loxapine in an attempt to taper or discontinue the weight gain-associated antipsychotic. Mean weight loss was −5.7 kg, mean BMI reduction was −1.9, and mean triglyceride reduction was −33.7 mg/dl. At chart review, 14 of 15 subjects were rated 2 (Much Improved) or 1 (Very Much Improved) on the Clinical Global Impressions-Improvement scale (CGI-I). Low dose loxapine addition in most cases enabled taper of offending antipsychotics, significantly reversed drug-induced metabolic disturbances and improved irritability. En ligne : http://dx.doi.org/10.1007/s10803-015-2675-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=284

Psychiatry training in autism spectrum disorder and intellectual disability: Ongoing gaps and emerging opportunities / Natasha M. MARRUS in Autism, 27-3 (April 2023)  

Public ISBD [article]  inAutism > 27-3 (April 2023) . - p.679-689 Titre : Psychiatry training in autism spectrum disorder and intellectual disability: Ongoing gaps and emerging opportunities Type de document : texte imprimé Auteurs : Natasha M. MARRUS, Auteur ; Kathleen A. KOTH, Auteur ; Jessica A. HELLINGS, Auteur ; Rachel G. MCDONALD, Auteur ; McLeod Frampton GWYNETTE, Auteur ; Rebecca A. MUHLE, Auteur ; William D LOHR, Auteur ; Roma A. VASA, Auteur Article en page(s) : p.679-689 Langues : Anglais (eng) Mots-clés : autism spectrum disorder,education,intellectual disability,psychiatry,residency training Index. décimale : PER Périodiques Résumé : Autism spectrum disorder and intellectual disability are associated with psychiatric comorbidities, yet a 2009 study of US child and adolescent psychiatry program directors indicated that psychiatry residents receive insufficient training in autism spectrum disorder/intellectual disability. This follow-up study surveyed child and adolescent psychiatry and general psychiatry program directors to assess (1) the current extent of residency training in autism spectrum disorder/intellectual disability, (2) program director perceptions of educational topics and resident competency in autism spectrum disorder/intellectual disability, and (3) preferred resources to strengthen autism spectrum disorder/intellectual disability training. As in 2009, many child and adolescent psychiatry program directors reported few lecture hours, although current child and adolescent psychiatry residents saw slightly more patients with autism spectrum disorder but not intellectual disability. General psychiatry program directors reported fewer lecture hours in autism spectrum disorder/intellectual disability and fewer patients with autism spectrum disorder than child and adolescent psychiatry program directors. Both child and adolescent psychiatry and general psychiatry program directors recognized the importance of a range of educational topics in autism spectrum disorder/intellectual disability. Child and adolescent psychiatry program directors reported higher resident competency, and lecture hours and patients seen moderately correlated with resident competency. Program directors indicated that online videos and other resources would help improve autism spectrum disorder/intellectual disability training in their programs. Collectively, these findings suggest minimal improvements in autism spectrum disorder/intellectual disability training over the past decade and highlight the urgent need to advance psychiatry training in this field through dissemination of resources.Lay abstractChildren, adolescents, and adults with autism spectrum disorder and intellectual disability experience high rates of co-occurring psychiatric conditions throughout their lifetime. However, there is a shortage of psychiatrists to treat these populations. We evaluated how much education psychiatrists-in-training receive on how to care for individuals with autism spectrum disorder/intellectual disability. We found that in many psychiatry programs, residents receive limited training experiences in autism spectrum disorder/intellectual disability involving lectures and patient contact and that psychiatry program directors would benefit from more resources to strengthen education in autism spectrum disorder/intellectual disability. En ligne : https://doi.org/10.1177/13623613221112197 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499 [article] Psychiatry training in autism spectrum disorder and intellectual disability: Ongoing gaps and emerging opportunities [texte imprimé] / Natasha M. MARRUS, Auteur ; Kathleen A. KOTH, Auteur ; Jessica A. HELLINGS, Auteur ; Rachel G. MCDONALD, Auteur ; McLeod Frampton GWYNETTE, Auteur ; Rebecca A. MUHLE, Auteur ; William D LOHR, Auteur ; Roma A. VASA, Auteur . - p.679-689. Langues : Anglais (eng) in Autism > 27-3 (April 2023) . - p.679-689 Mots-clés : autism spectrum disorder,education,intellectual disability,psychiatry,residency training Index. décimale : PER Périodiques Résumé : Autism spectrum disorder and intellectual disability are associated with psychiatric comorbidities, yet a 2009 study of US child and adolescent psychiatry program directors indicated that psychiatry residents receive insufficient training in autism spectrum disorder/intellectual disability. This follow-up study surveyed child and adolescent psychiatry and general psychiatry program directors to assess (1) the current extent of residency training in autism spectrum disorder/intellectual disability, (2) program director perceptions of educational topics and resident competency in autism spectrum disorder/intellectual disability, and (3) preferred resources to strengthen autism spectrum disorder/intellectual disability training. As in 2009, many child and adolescent psychiatry program directors reported few lecture hours, although current child and adolescent psychiatry residents saw slightly more patients with autism spectrum disorder but not intellectual disability. General psychiatry program directors reported fewer lecture hours in autism spectrum disorder/intellectual disability and fewer patients with autism spectrum disorder than child and adolescent psychiatry program directors. Both child and adolescent psychiatry and general psychiatry program directors recognized the importance of a range of educational topics in autism spectrum disorder/intellectual disability. Child and adolescent psychiatry program directors reported higher resident competency, and lecture hours and patients seen moderately correlated with resident competency. Program directors indicated that online videos and other resources would help improve autism spectrum disorder/intellectual disability training in their programs. Collectively, these findings suggest minimal improvements in autism spectrum disorder/intellectual disability training over the past decade and highlight the urgent need to advance psychiatry training in this field through dissemination of resources.Lay abstractChildren, adolescents, and adults with autism spectrum disorder and intellectual disability experience high rates of co-occurring psychiatric conditions throughout their lifetime. However, there is a shortage of psychiatrists to treat these populations. We evaluated how much education psychiatrists-in-training receive on how to care for individuals with autism spectrum disorder/intellectual disability. We found that in many psychiatry programs, residents receive limited training experiences in autism spectrum disorder/intellectual disability involving lectures and patient contact and that psychiatry program directors would benefit from more resources to strengthen education in autism spectrum disorder/intellectual disability. En ligne : https://doi.org/10.1177/13623613221112197 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499

A Retrospective Study of Amitriptyline in Youth with Autism Spectrum Disorders / Irfan BHATTI in Journal of Autism and Developmental Disorders, 43-5 (May 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1017-1027 Titre : A Retrospective Study of Amitriptyline in Youth with Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Irfan BHATTI, Auteur ; Andrew THOME, Auteur ; Patricia OXLER SMITH, Auteur ; Galen COOK-WIENS, Auteur ; Hung Wen YEH, Auteur ; Gary GAFFNEY, Auteur ; Jessica A. HELLINGS, Auteur Article en page(s) : p.1017-1027 Langues : Anglais (eng) Mots-clés : Amitriptyline  Autism Spectrum Disorders  Hyperactivity  Impulsivity Index. décimale : PER Périodiques Résumé : We performed a retrospective chart review of 50 youths with Autism Spectrum Disorder (ASD), prescribed amitriptyline (AMI) for hyperactivity and impulsivity. Data was systematically extracted from 50 outpatient clinic charts, including AMI treatment duration, dose, trough levels and adverse events. Mean age was 9.4 years (4.6–17.9); 40 were males and 10 females. 30 % had failed atomoxetine and 40 % had failed ≥3 ADHD medications. Mean dose was 1.3 ± 0.6 mg/kg/day, mean trough level 114.1 ± 50.5 ng/ml, mean duration 3.4 years. Clinical Global Impressions Scale-Improvement (CGI-I) was ≤2 in 60 % of patients at the final visit, and in 82 % of patients for at least 50 % of follow-ups. Cautious use of low dose AMI shows promise for treatment-resistant youth with ASD accompanied by hyperactivity, impulsivity, aggression and self injury. En ligne : http://dx.doi.org/10.1007/s10803-012-1647-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=195 [article] A Retrospective Study of Amitriptyline in Youth with Autism Spectrum Disorders [texte imprimé] / Irfan BHATTI, Auteur ; Andrew THOME, Auteur ; Patricia OXLER SMITH, Auteur ; Galen COOK-WIENS, Auteur ; Hung Wen YEH, Auteur ; Gary GAFFNEY, Auteur ; Jessica A. HELLINGS, Auteur . - p.1017-1027. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1017-1027 Mots-clés : Amitriptyline  Autism Spectrum Disorders  Hyperactivity  Impulsivity Index. décimale : PER Périodiques Résumé : We performed a retrospective chart review of 50 youths with Autism Spectrum Disorder (ASD), prescribed amitriptyline (AMI) for hyperactivity and impulsivity. Data was systematically extracted from 50 outpatient clinic charts, including AMI treatment duration, dose, trough levels and adverse events. Mean age was 9.4 years (4.6–17.9); 40 were males and 10 females. 30 % had failed atomoxetine and 40 % had failed ≥3 ADHD medications. Mean dose was 1.3 ± 0.6 mg/kg/day, mean trough level 114.1 ± 50.5 ng/ml, mean duration 3.4 years. Clinical Global Impressions Scale-Improvement (CGI-I) was ≤2 in 60 % of patients at the final visit, and in 82 % of patients for at least 50 % of follow-ups. Cautious use of low dose AMI shows promise for treatment-resistant youth with ASD accompanied by hyperactivity, impulsivity, aggression and self injury. En ligne : http://dx.doi.org/10.1007/s10803-012-1647-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=195

Training of child and adolescent psychiatry fellows in autism and intellectual disability / Natasha M. MARRUS in Autism, 18-4 (May 2014)  

Permalink

---

1 (1 - 6 / 6) Par page : 25 50 100 200