Dépouillements

Circuits underlying social function and dysfunction / Ziwen WANG in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1268-1288 Titre : Circuits underlying social function and dysfunction Type de document : Texte imprimé et/ou numérique Auteurs : Ziwen WANG, Auteur ; Hannah YUEH, Auteur ; Mirabella CHAU, Auteur ; Jeremy VEENSTRA-VANDERWEELE, Auteur ; Kally C. O'REILLY, Auteur Article en page(s) : p.1268-1288 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Substantial advances have been made toward understanding the genetic and environmental risk factors for autism, a neurodevelopmental disorder with social impairment as a core feature. In combination with optogenetic and chemogenetic tools to manipulate neural circuits in vivo, it is now possible to use model systems to test how specific neural circuits underlie social function and dysfunction. Here, we review the literature that has identified circuits associated with social interest (sociability), social reward, social memory, dominance, and aggression, and we outline a preliminary roadmap of the neural circuits driving these social behaviors. We highlight the neural circuitry underlying each behavioral domain, as well as develop an interactive map of how these circuits overlap across domains. We find that some of the circuits underlying social behavior are general and are involved in the control of multiple behavioral aspects, whereas other circuits appear to be specialized for specific aspects of social behavior. Our overlapping circuit map therefore helps to delineate the circuits involved in the various domains of social behavior and to identify gaps in knowledge. En ligne : https://doi.org/10.1002/aur.2978 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Circuits underlying social function and dysfunction [Texte imprimé et/ou numérique] / Ziwen WANG, Auteur ; Hannah YUEH, Auteur ; Mirabella CHAU, Auteur ; Jeremy VEENSTRA-VANDERWEELE, Auteur ; Kally C. O'REILLY, Auteur . - p.1268-1288. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1268-1288 Index. décimale : PER Périodiques Résumé : Abstract Substantial advances have been made toward understanding the genetic and environmental risk factors for autism, a neurodevelopmental disorder with social impairment as a core feature. In combination with optogenetic and chemogenetic tools to manipulate neural circuits in vivo, it is now possible to use model systems to test how specific neural circuits underlie social function and dysfunction. Here, we review the literature that has identified circuits associated with social interest (sociability), social reward, social memory, dominance, and aggression, and we outline a preliminary roadmap of the neural circuits driving these social behaviors. We highlight the neural circuitry underlying each behavioral domain, as well as develop an interactive map of how these circuits overlap across domains. We find that some of the circuits underlying social behavior are general and are involved in the control of multiple behavioral aspects, whereas other circuits appear to be specialized for specific aspects of social behavior. Our overlapping circuit map therefore helps to delineate the circuits involved in the various domains of social behavior and to identify gaps in knowledge. En ligne : https://doi.org/10.1002/aur.2978 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

What are quantitative traits and how can they be used in autism research? / Kristen LYALL in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1289-1298 Titre : What are quantitative traits and how can they be used in autism research? Type de document : Texte imprimé et/ou numérique Auteurs : Kristen LYALL, Auteur Article en page(s) : p.1289-1298 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Quantitative traits are measurable characteristics distributed along a continuous scale thought to relate to underlying biology. There is growing interest in the use of quantitative traits in behavioral and psychiatric research, particularly in research on conditions diagnosed based on reports of behaviors, including autism. This brief commentary describes quantitative traits, including defining what they are, how we can measure them, and key considerations for their use in autism research. Examples of measures include behavioral report scales like the Social Responsiveness Scale and Broader Autism Phenotype Questionnaire, as well as biological measurements, like certain neuroimaging metrics; such measures can capture quantitative traits or constructs like the broader autism phenotype, social communication, and social cognition. Quantitative trait measures align with the Research Domain Criteria (RDoC) approach and can be used in autism research to help gain a better understanding of causal pathways and biological processes. They can also be used to aid identification of genetic and environmental factors involved in such pathways, and thereby lead to an understanding of influences on traits across the entire population. Finally, in some cases, they may be used to gauge treatment response, and assist screening and clinical characterization of phenotype. In addition, practical benefits of quantitative trait measures include improved statistical power relative to categorical classifications and (for some measures) efficiency. Ultimately, research across autism fields may benefit from incorporating quantitative trait measures as a complement to categorical diagnosis to advance understanding of autism and neurodevelopment. En ligne : https://doi.org/10.1002/aur.2937 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] What are quantitative traits and how can they be used in autism research? [Texte imprimé et/ou numérique] / Kristen LYALL, Auteur . - p.1289-1298. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1289-1298 Index. décimale : PER Périodiques Résumé : Abstract Quantitative traits are measurable characteristics distributed along a continuous scale thought to relate to underlying biology. There is growing interest in the use of quantitative traits in behavioral and psychiatric research, particularly in research on conditions diagnosed based on reports of behaviors, including autism. This brief commentary describes quantitative traits, including defining what they are, how we can measure them, and key considerations for their use in autism research. Examples of measures include behavioral report scales like the Social Responsiveness Scale and Broader Autism Phenotype Questionnaire, as well as biological measurements, like certain neuroimaging metrics; such measures can capture quantitative traits or constructs like the broader autism phenotype, social communication, and social cognition. Quantitative trait measures align with the Research Domain Criteria (RDoC) approach and can be used in autism research to help gain a better understanding of causal pathways and biological processes. They can also be used to aid identification of genetic and environmental factors involved in such pathways, and thereby lead to an understanding of influences on traits across the entire population. Finally, in some cases, they may be used to gauge treatment response, and assist screening and clinical characterization of phenotype. In addition, practical benefits of quantitative trait measures include improved statistical power relative to categorical classifications and (for some measures) efficiency. Ultimately, research across autism fields may benefit from incorporating quantitative trait measures as a complement to categorical diagnosis to advance understanding of autism and neurodevelopment. En ligne : https://doi.org/10.1002/aur.2937 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

A multilevel investigation of sensory sensitivity and responsivity in autistic adults / Laurie-Anne SAPEY-TRIOMPHE in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1299-1320 Titre : A multilevel investigation of sensory sensitivity and responsivity in autistic adults Type de document : Texte imprimé et/ou numérique Auteurs : Laurie-Anne SAPEY-TRIOMPHE, Auteur ; Joke DIERCKX, Auteur ; Sofie VETTORI, Auteur ; Jaana VAN OVERWALLE, Auteur ; Johan WAGEMANS, Auteur Article en page(s) : p.1299-1320 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Atypical sensory processing is a core symptom of autism spectrum disorders (ASD). We aimed at better characterizing visual sensitivity and responsivity in ASD at the self-reported, behavioral and neural levels, and at describing the relationships between these levels. We refer to sensory sensitivity as the ability to detect sensory stimuli and to sensory responsivity as an affective response to sensory stimuli. Participants were 25 neurotypical and 24 autistic adults. At the self-reported level, autistic participants had higher scores of sensory sensitivity and responsivity than neurotypicals. The behavioral and neural tasks involved contrast-reversing gratings which became progressively (in)visible as their contrast or spatial frequency evolved. At the behavioral level, autistic participants had higher detection and responsivity thresholds when gratings varied in spatial frequency, but their thresholds did not differ from neurotypicals when gratings varied in contrast. At the neural level, we used fast periodic visual stimulations and electroencephalography to implicitly assess detection thresholds for contrast and spatial frequency, and did not reveal any group difference. Higher self-reported responsivity was associated with higher behavioral responsivity, more intolerance of uncertainty and anxiety, in particular in ASD. At the self-reported level, higher sensitivity was associated with more responsivity in both groups, contrary to the behavioral level where these relationships were not found. These heterogeneous results suggest that sensitivity and responsivity per se are not simply increased in ASD, but may be modulated by other factors such as environmental predictability. Multi-level approaches can shed light on the mechanisms underlying sensory issues in ASD. En ligne : https://doi.org/10.1002/aur.2962 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] A multilevel investigation of sensory sensitivity and responsivity in autistic adults [Texte imprimé et/ou numérique] / Laurie-Anne SAPEY-TRIOMPHE, Auteur ; Joke DIERCKX, Auteur ; Sofie VETTORI, Auteur ; Jaana VAN OVERWALLE, Auteur ; Johan WAGEMANS, Auteur . - p.1299-1320. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1299-1320 Index. décimale : PER Périodiques Résumé : Abstract Atypical sensory processing is a core symptom of autism spectrum disorders (ASD). We aimed at better characterizing visual sensitivity and responsivity in ASD at the self-reported, behavioral and neural levels, and at describing the relationships between these levels. We refer to sensory sensitivity as the ability to detect sensory stimuli and to sensory responsivity as an affective response to sensory stimuli. Participants were 25 neurotypical and 24 autistic adults. At the self-reported level, autistic participants had higher scores of sensory sensitivity and responsivity than neurotypicals. The behavioral and neural tasks involved contrast-reversing gratings which became progressively (in)visible as their contrast or spatial frequency evolved. At the behavioral level, autistic participants had higher detection and responsivity thresholds when gratings varied in spatial frequency, but their thresholds did not differ from neurotypicals when gratings varied in contrast. At the neural level, we used fast periodic visual stimulations and electroencephalography to implicitly assess detection thresholds for contrast and spatial frequency, and did not reveal any group difference. Higher self-reported responsivity was associated with higher behavioral responsivity, more intolerance of uncertainty and anxiety, in particular in ASD. At the self-reported level, higher sensitivity was associated with more responsivity in both groups, contrary to the behavioral level where these relationships were not found. These heterogeneous results suggest that sensitivity and responsivity per se are not simply increased in ASD, but may be modulated by other factors such as environmental predictability. Multi-level approaches can shed light on the mechanisms underlying sensory issues in ASD. En ligne : https://doi.org/10.1002/aur.2962 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Non-autistic adults can recognize posed autistic facial expressions: Implications for internal representations of emotion / Andrew J. LAMPI in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1321-1334 Titre : Non-autistic adults can recognize posed autistic facial expressions: Implications for internal representations of emotion Type de document : Texte imprimé et/ou numérique Auteurs : Andrew J. LAMPI, Auteur ; Rebecca BREWER, Auteur ; Geoffrey BIRD, Auteur ; Vikram K. JASWAL, Auteur Article en page(s) : p.1321-1334 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Autistic people report that their emotional expressions are sometimes misunderstood by non-autistic people. One explanation for these misunderstandings could be that the two neurotypes have different internal representations of emotion: Perhaps they have different expectations about what a facial expression showing a particular emotion looks like. In three well-powered studies with non-autistic college students in the United States (total N=632), we investigated this possibility. In Study 1, participants recognized most facial expressions posed by autistic individuals more accurately than those posed by non-autistic individuals. Study 2 showed that one reason the autistic expressions were recognized more accurately was because they were better and more intense examples of the intended expressions than the non-autistic expressions. In Study 3, we used a set of expressions created by autistic and non-autistic individuals who could see their faces as they made the expressions, which could allow them to explicitly match the expression they produced with their internal representation of that emotional expression. Here, neither autistic expressions nor non-autistic expressions were consistently recognized more accurately. In short, these findings suggest that differences in internal representations of what emotional expressions look like are unlikely to play a major role in explaining why non-autistic people sometimes misunderstand the emotions autistic people are experiencing. En ligne : https://doi.org/10.1002/aur.2938 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Non-autistic adults can recognize posed autistic facial expressions: Implications for internal representations of emotion [Texte imprimé et/ou numérique] / Andrew J. LAMPI, Auteur ; Rebecca BREWER, Auteur ; Geoffrey BIRD, Auteur ; Vikram K. JASWAL, Auteur . - p.1321-1334. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1321-1334 Index. décimale : PER Périodiques Résumé : Abstract Autistic people report that their emotional expressions are sometimes misunderstood by non-autistic people. One explanation for these misunderstandings could be that the two neurotypes have different internal representations of emotion: Perhaps they have different expectations about what a facial expression showing a particular emotion looks like. In three well-powered studies with non-autistic college students in the United States (total N=632), we investigated this possibility. In Study 1, participants recognized most facial expressions posed by autistic individuals more accurately than those posed by non-autistic individuals. Study 2 showed that one reason the autistic expressions were recognized more accurately was because they were better and more intense examples of the intended expressions than the non-autistic expressions. In Study 3, we used a set of expressions created by autistic and non-autistic individuals who could see their faces as they made the expressions, which could allow them to explicitly match the expression they produced with their internal representation of that emotional expression. Here, neither autistic expressions nor non-autistic expressions were consistently recognized more accurately. In short, these findings suggest that differences in internal representations of what emotional expressions look like are unlikely to play a major role in explaining why non-autistic people sometimes misunderstand the emotions autistic people are experiencing. En ligne : https://doi.org/10.1002/aur.2938 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Autism severity level affects working memory and planning but not inhibition, shifting and emotional control / Haris MEMISEVIC in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1335-1343 Titre : Autism severity level affects working memory and planning but not inhibition, shifting and emotional control Type de document : Texte imprimé et/ou numérique Auteurs : Haris MEMISEVIC, Auteur ; Arnela PASALIC, Auteur ; Amra SALETOVIC, Auteur Article en page(s) : p.1335-1343 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Autistic children often have difficulties in executive functions (EF). These difficulties can, in turn, affect their everyday functioning. It is less clear in what way EF are affected by the severity of autism symptoms in children. We hypothesize that autism severity level does not have the same effect across the different components of EF. In this study, we examined how EF are affected by the autism severity level in a sample of 52 autistic children aged 4-7?years (mean age- 5.4?years, SD- 0.9?years). EF were measured through teachers' reports on the Behavior Rating Inventory of Executive Functions- Preschool Version. Autism severity level was measured with the Social Communication Questionnaire- Current Form. The results of this study showed that autism severity level impacted two EF, namely Planning and Working memory, and did not affect three EF components: Inhibition, Shifting, and Emotional Control. These results indicate that the cool or cognitive EF are more affected by autism severity level than hot EF. We conclude the article with suggestions for improving EF in autistic children. En ligne : https://doi.org/10.1002/aur.2952 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Autism severity level affects working memory and planning but not inhibition, shifting and emotional control [Texte imprimé et/ou numérique] / Haris MEMISEVIC, Auteur ; Arnela PASALIC, Auteur ; Amra SALETOVIC, Auteur . - p.1335-1343. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1335-1343 Index. décimale : PER Périodiques Résumé : Abstract Autistic children often have difficulties in executive functions (EF). These difficulties can, in turn, affect their everyday functioning. It is less clear in what way EF are affected by the severity of autism symptoms in children. We hypothesize that autism severity level does not have the same effect across the different components of EF. In this study, we examined how EF are affected by the autism severity level in a sample of 52 autistic children aged 4-7?years (mean age- 5.4?years, SD- 0.9?years). EF were measured through teachers' reports on the Behavior Rating Inventory of Executive Functions- Preschool Version. Autism severity level was measured with the Social Communication Questionnaire- Current Form. The results of this study showed that autism severity level impacted two EF, namely Planning and Working memory, and did not affect three EF components: Inhibition, Shifting, and Emotional Control. These results indicate that the cool or cognitive EF are more affected by autism severity level than hot EF. We conclude the article with suggestions for improving EF in autistic children. En ligne : https://doi.org/10.1002/aur.2952 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Developmental profiles of young children with autism spectrum disorder and global developmental delay: A study with the Griffiths III scales / Matilde TADDEI in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1344-1359 Titre : Developmental profiles of young children with autism spectrum disorder and global developmental delay: A study with the Griffiths III scales Type de document : Texte imprimé et/ou numérique Auteurs : Matilde TADDEI, Auteur ; Sara BULGHERONI, Auteur ; Enrico TOFFALINI, Auteur ; Chiara PANTALEONI, Auteur ; Silvia LANFRANCHI, Auteur Article en page(s) : p.1344-1359 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract The purpose of this study was to identify developmental profiles associated with autism spectrum disorder (ASD) and global developmental delay (DD) in pre-school aged Italian children. Developmental profiles were evaluated by means of a standardized tool widely used for the assessment of psychomotor development in early childhood, the Griffiths III scales, recently adapted and standardized for the Italian population. Specifically, we compared the Griffiths III profiles of children with ASD and DD (ASD?+?DD) with those of children with DD alone. Moreover, we inspected the psychometric function of single items by comparing children with ASD?+?DD and children with DD with typically developing (TD) children from the Griffiths III normative sample. In this way, we aimed to isolate the effects of each diagnostic class on psychomotor abilities and on the psychometric function of single items. The ASD?+?DD and DD groups were found to share the presence of lower age equivalent scores relative to their chronological age in all the developmental domains considered: Foundations of Learning, Language and Communication, Eye and Hand Coordination, Personal-Social-Emotional and Gross Motor Skills. However, the DD group displayed a homogeneous profile with similar levels of delay in all developmental domains, while children with ASD?+?DD exhibited relative weaknesses in the Language and Communication and Personal-Social-Emotional scales. The analysis of the psychometric function drawn for each item has confirmed different profiles in social-communicative and non-verbal items between the two diagnostic groups and in relation to TD normative sample. The Griffiths III is a valid psychometric tool for identifying atypical developmental profiles and its use may be recommended during the diagnostic process of ASD and DD, to detect specific strengths and weaknesses and guide person-centered treatment. En ligne : https://doi.org/10.1002/aur.2953 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Developmental profiles of young children with autism spectrum disorder and global developmental delay: A study with the Griffiths III scales [Texte imprimé et/ou numérique] / Matilde TADDEI, Auteur ; Sara BULGHERONI, Auteur ; Enrico TOFFALINI, Auteur ; Chiara PANTALEONI, Auteur ; Silvia LANFRANCHI, Auteur . - p.1344-1359. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1344-1359 Index. décimale : PER Périodiques Résumé : Abstract The purpose of this study was to identify developmental profiles associated with autism spectrum disorder (ASD) and global developmental delay (DD) in pre-school aged Italian children. Developmental profiles were evaluated by means of a standardized tool widely used for the assessment of psychomotor development in early childhood, the Griffiths III scales, recently adapted and standardized for the Italian population. Specifically, we compared the Griffiths III profiles of children with ASD and DD (ASD?+?DD) with those of children with DD alone. Moreover, we inspected the psychometric function of single items by comparing children with ASD?+?DD and children with DD with typically developing (TD) children from the Griffiths III normative sample. In this way, we aimed to isolate the effects of each diagnostic class on psychomotor abilities and on the psychometric function of single items. The ASD?+?DD and DD groups were found to share the presence of lower age equivalent scores relative to their chronological age in all the developmental domains considered: Foundations of Learning, Language and Communication, Eye and Hand Coordination, Personal-Social-Emotional and Gross Motor Skills. However, the DD group displayed a homogeneous profile with similar levels of delay in all developmental domains, while children with ASD?+?DD exhibited relative weaknesses in the Language and Communication and Personal-Social-Emotional scales. The analysis of the psychometric function drawn for each item has confirmed different profiles in social-communicative and non-verbal items between the two diagnostic groups and in relation to TD normative sample. The Griffiths III is a valid psychometric tool for identifying atypical developmental profiles and its use may be recommended during the diagnostic process of ASD and DD, to detect specific strengths and weaknesses and guide person-centered treatment. En ligne : https://doi.org/10.1002/aur.2953 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Relationship between quantitative digital behavioral features and clinical profiles in young autistic children / Marika COFFMAN in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1360-1374 Titre : Relationship between quantitative digital behavioral features and clinical profiles in young autistic children Type de document : Texte imprimé et/ou numérique Auteurs : Marika COFFMAN, Auteur ; J. Matias DI MARTINO, Auteur ; Rachel AIELLO, Auteur ; Kimberly L. H. CARPENTER, Auteur ; Zhuoqing CHANG, Auteur ; Scott COMPTON, Auteur ; Brian EICHNER, Auteur ; Steve ESPINOSA, Auteur ; Jacqueline FLOWERS, Auteur ; Lauren FRANZ, Auteur ; Sam PEROCHON, Auteur ; Pradeep Raj KRISHNAPPA BABU, Auteur ; Guillermo SAPIRO, Auteur ; Geraldine DAWSON, Auteur Article en page(s) : p.1360-1374 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Early behavioral markers for autism include differences in social attention and orienting in response to one's name when called, and differences in body movements and motor abilities. More efficient, scalable, objective, and reliable measures of these behaviors could improve early screening for autism. This study evaluated whether objective and quantitative measures of autism-related behaviors elicited from an app (SenseToKnow) administered on a smartphone or tablet and measured via computer vision analysis (CVA) are correlated with standardized caregiver-report and clinician administered measures of autism-related behaviors and cognitive, language, and motor abilities. This is an essential step in establishing the concurrent validity of a digital phenotyping approach. In a sample of 485 toddlers, 43 of whom were diagnosed with autism, we found that CVA-based gaze variables related to social attention were associated with the level of autism-related behaviors. Two language-related behaviors measured via the app, attention to people during a conversation and responding to one's name being called, were associated with children's language skills. Finally, performance during a bubble popping game was associated with fine motor skills. These findings provide initial support for the concurrent validity of the SenseToKnow app and its potential utility in identifying clinical profiles associated with autism. Future research is needed to determine whether the app can be used as an autism screening tool, can reliably stratify autism-related behaviors, and measure changes in autism-related behaviors over time. En ligne : https://doi.org/10.1002/aur.2955 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Relationship between quantitative digital behavioral features and clinical profiles in young autistic children [Texte imprimé et/ou numérique] / Marika COFFMAN, Auteur ; J. Matias DI MARTINO, Auteur ; Rachel AIELLO, Auteur ; Kimberly L. H. CARPENTER, Auteur ; Zhuoqing CHANG, Auteur ; Scott COMPTON, Auteur ; Brian EICHNER, Auteur ; Steve ESPINOSA, Auteur ; Jacqueline FLOWERS, Auteur ; Lauren FRANZ, Auteur ; Sam PEROCHON, Auteur ; Pradeep Raj KRISHNAPPA BABU, Auteur ; Guillermo SAPIRO, Auteur ; Geraldine DAWSON, Auteur . - p.1360-1374. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1360-1374 Index. décimale : PER Périodiques Résumé : Abstract Early behavioral markers for autism include differences in social attention and orienting in response to one's name when called, and differences in body movements and motor abilities. More efficient, scalable, objective, and reliable measures of these behaviors could improve early screening for autism. This study evaluated whether objective and quantitative measures of autism-related behaviors elicited from an app (SenseToKnow) administered on a smartphone or tablet and measured via computer vision analysis (CVA) are correlated with standardized caregiver-report and clinician administered measures of autism-related behaviors and cognitive, language, and motor abilities. This is an essential step in establishing the concurrent validity of a digital phenotyping approach. In a sample of 485 toddlers, 43 of whom were diagnosed with autism, we found that CVA-based gaze variables related to social attention were associated with the level of autism-related behaviors. Two language-related behaviors measured via the app, attention to people during a conversation and responding to one's name being called, were associated with children's language skills. Finally, performance during a bubble popping game was associated with fine motor skills. These findings provide initial support for the concurrent validity of the SenseToKnow app and its potential utility in identifying clinical profiles associated with autism. Future research is needed to determine whether the app can be used as an autism screening tool, can reliably stratify autism-related behaviors, and measure changes in autism-related behaviors over time. En ligne : https://doi.org/10.1002/aur.2955 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Atypical facial mimicry for basic emotions in children with autism spectrum disorder / Shuo LIU in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1375-1388 Titre : Atypical facial mimicry for basic emotions in children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Shuo LIU, Auteur ; Yue WANG, Auteur ; Yongning SONG, Auteur Article en page(s) : p.1375-1388 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract During social encounters, people tend to reproduce the facial expressions of others, termed "facial mimicry," which is believed to underlie many important social cognitive functions. Clinically, atypical mimicry is closely associated with serious social dysfunction. However, findings regarding the facial mimicry ability of children with autism spectrum disorder (ASD) are inconsistent; it is necessary to test whether deficits in facial mimicry are core defects of autism and explore the potential mechanism underlying this process. Using quantitative analysis, this study investigated voluntary and automatic facial mimicry performance of six basic expressions in children with and without ASD. There was no significant group difference in mimicry accuracy, but children with ASD showed less intensity in voluntary and automatic mimicry than typically developing children; they also presented less voluntary mimicry intensity for happy, sad, and fearful expressions. Performance on voluntary and automatic mimicry was significantly correlated with the level of autistic symptoms (r >-.43) and theory of mind (r >.34). Furthermore, theory of mind mediated the relationship between autistic symptoms and the intensity of facial mimicry. These results suggest that individuals with ASD show atypical facial mimicry (i.e., less intensity for both voluntary and automatic mimicry, mainly for voluntary mimicry of happiness, sadness, and fear), which might offer a potential cognitive marker for quantifying syndrome manifestations in children with ASD. These findings suggest that theory of mind plays a mediating role in facial mimicry, which may provide insight into the theoretical mechanism of social dysfunction in children with autism. En ligne : https://doi.org/10.1002/aur.2957 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Atypical facial mimicry for basic emotions in children with autism spectrum disorder [Texte imprimé et/ou numérique] / Shuo LIU, Auteur ; Yue WANG, Auteur ; Yongning SONG, Auteur . - p.1375-1388. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1375-1388 Index. décimale : PER Périodiques Résumé : Abstract During social encounters, people tend to reproduce the facial expressions of others, termed "facial mimicry," which is believed to underlie many important social cognitive functions. Clinically, atypical mimicry is closely associated with serious social dysfunction. However, findings regarding the facial mimicry ability of children with autism spectrum disorder (ASD) are inconsistent; it is necessary to test whether deficits in facial mimicry are core defects of autism and explore the potential mechanism underlying this process. Using quantitative analysis, this study investigated voluntary and automatic facial mimicry performance of six basic expressions in children with and without ASD. There was no significant group difference in mimicry accuracy, but children with ASD showed less intensity in voluntary and automatic mimicry than typically developing children; they also presented less voluntary mimicry intensity for happy, sad, and fearful expressions. Performance on voluntary and automatic mimicry was significantly correlated with the level of autistic symptoms (r >-.43) and theory of mind (r >.34). Furthermore, theory of mind mediated the relationship between autistic symptoms and the intensity of facial mimicry. These results suggest that individuals with ASD show atypical facial mimicry (i.e., less intensity for both voluntary and automatic mimicry, mainly for voluntary mimicry of happiness, sadness, and fear), which might offer a potential cognitive marker for quantifying syndrome manifestations in children with ASD. These findings suggest that theory of mind plays a mediating role in facial mimicry, which may provide insight into the theoretical mechanism of social dysfunction in children with autism. En ligne : https://doi.org/10.1002/aur.2957 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

What is specific about employment status, workplace experiences and requirements in individuals with autism in Germany? / Julia ESPELÖER in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1389-1402 Titre : What is specific about employment status, workplace experiences and requirements in individuals with autism in Germany? Type de document : Texte imprimé et/ou numérique Auteurs : Julia ESPELÖER, Auteur ; Julia PROFT, Auteur ; Phyllis KEMMER, Auteur ; Christine M. FALTER-WAGNER, Auteur ; Kai VOGELEY, Auteur Article en page(s) : p.1389-1402 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract The challenge of sustainably integrating highly educated individuals with ASD without intellectual disabilities in the first labor market is repeatedly described in literature. In a retrospective study, a group of 197 clinically late-diagnosed adults with ASD without intellectual disabilities was compared to a closely matched group of 501 individuals who did not meet the criteria for the diagnosis of ASD within a utilization population of the Cologne Autism Outpatient Clinic. Results indicated that the pronounced demand for reduction of social and interpersonal requirements at the workplace (including planned or limited contact with colleagues and customers) as well as the experience of difficulties following unexpected changes in the daily routine were specific for ASD. In addition, individuals with ASD reported greater difficulties in finding a suitable job and being able to live on their wages, taking age and educational qualification into account. Supported employment measures were provided significantly more frequently to individuals in the ASD group. In conclusion, impairments in social skills emerged as one of the main obstacles of workplace performance for individuals with ASD emphasizing the necessity to develop and apply ASD-specific support services. En ligne : https://doi.org/10.1002/aur.2958 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] What is specific about employment status, workplace experiences and requirements in individuals with autism in Germany? [Texte imprimé et/ou numérique] / Julia ESPELÖER, Auteur ; Julia PROFT, Auteur ; Phyllis KEMMER, Auteur ; Christine M. FALTER-WAGNER, Auteur ; Kai VOGELEY, Auteur . - p.1389-1402. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1389-1402 Index. décimale : PER Périodiques Résumé : Abstract The challenge of sustainably integrating highly educated individuals with ASD without intellectual disabilities in the first labor market is repeatedly described in literature. In a retrospective study, a group of 197 clinically late-diagnosed adults with ASD without intellectual disabilities was compared to a closely matched group of 501 individuals who did not meet the criteria for the diagnosis of ASD within a utilization population of the Cologne Autism Outpatient Clinic. Results indicated that the pronounced demand for reduction of social and interpersonal requirements at the workplace (including planned or limited contact with colleagues and customers) as well as the experience of difficulties following unexpected changes in the daily routine were specific for ASD. In addition, individuals with ASD reported greater difficulties in finding a suitable job and being able to live on their wages, taking age and educational qualification into account. Supported employment measures were provided significantly more frequently to individuals in the ASD group. In conclusion, impairments in social skills emerged as one of the main obstacles of workplace performance for individuals with ASD emphasizing the necessity to develop and apply ASD-specific support services. En ligne : https://doi.org/10.1002/aur.2958 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Trajectories of internalizing symptoms among autistic and nonautistic youth during the COVID-19 pandemic / Talena C. DAY in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1403-1412 Titre : Trajectories of internalizing symptoms among autistic and nonautistic youth during the COVID-19 pandemic Type de document : Texte imprimé et/ou numérique Auteurs : Talena C. DAY, Auteur ; Alan GERBER, Auteur ; Morgan L. MCNAIR, Auteur ; Debra REICHER, Auteur ; Matthew D. LERNER, Auteur Article en page(s) : p.1403-1412 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract The COVID-19 pandemic elicited increases in anxiety and depression in youth, and youth on the autism spectrum demonstrate elevations in such symptoms pre-pandemic. However, it is unclear whether autistic youth experienced similar increases in internalizing symptoms after the COVID-19 pandemic onset or whether decreases in these symptoms were present, as speculated in qualitative work. In the current study, longitudinal changes in anxiety and depression during the COVID-19 pandemic in autistic youth were assessed in comparison to nonautistic youth. A well-characterized sample of 51 autistic and 25 nonautistic youth (ageM=12.8, range=8.5-17.4?years, IQ>70) and their parents completed the Revised Children's Anxiety and Depression Scale (RCADS), a measure of internalizing symptoms, repeatedly, representing up to 7 measurement occasions from June to December 2020 (N?~?419 occasions). Multilevel models were used to evaluate changes in internalizing symptoms over time. Internalizing symptoms did not differ between autistic and nonautistic youth in the summer of 2020. As reported by youth themselves, internalizing symptoms decreased in autistic youth, both overall and compared to nonautstic peers. This effect was driven by decreases in generalized anxiety, social anxiety, and depression symptoms in autistic youth. Reductions in generalized anxiety, social anxiety, and depression in autistic youth may be due to COVID-19 pandemic-specific differences in response to social, environmental, and contextual changes that unfolded in 2020. This highlights the importance of understanding unique protective and resilience factors that may be evident in autistic individuals in response to broad societal shifts such as those seen in response to COVID-19. En ligne : https://doi.org/10.1002/aur.2959 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Trajectories of internalizing symptoms among autistic and nonautistic youth during the COVID-19 pandemic [Texte imprimé et/ou numérique] / Talena C. DAY, Auteur ; Alan GERBER, Auteur ; Morgan L. MCNAIR, Auteur ; Debra REICHER, Auteur ; Matthew D. LERNER, Auteur . - p.1403-1412. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1403-1412 Index. décimale : PER Périodiques Résumé : Abstract The COVID-19 pandemic elicited increases in anxiety and depression in youth, and youth on the autism spectrum demonstrate elevations in such symptoms pre-pandemic. However, it is unclear whether autistic youth experienced similar increases in internalizing symptoms after the COVID-19 pandemic onset or whether decreases in these symptoms were present, as speculated in qualitative work. In the current study, longitudinal changes in anxiety and depression during the COVID-19 pandemic in autistic youth were assessed in comparison to nonautistic youth. A well-characterized sample of 51 autistic and 25 nonautistic youth (ageM=12.8, range=8.5-17.4?years, IQ>70) and their parents completed the Revised Children's Anxiety and Depression Scale (RCADS), a measure of internalizing symptoms, repeatedly, representing up to 7 measurement occasions from June to December 2020 (N?~?419 occasions). Multilevel models were used to evaluate changes in internalizing symptoms over time. Internalizing symptoms did not differ between autistic and nonautistic youth in the summer of 2020. As reported by youth themselves, internalizing symptoms decreased in autistic youth, both overall and compared to nonautstic peers. This effect was driven by decreases in generalized anxiety, social anxiety, and depression symptoms in autistic youth. Reductions in generalized anxiety, social anxiety, and depression in autistic youth may be due to COVID-19 pandemic-specific differences in response to social, environmental, and contextual changes that unfolded in 2020. This highlights the importance of understanding unique protective and resilience factors that may be evident in autistic individuals in response to broad societal shifts such as those seen in response to COVID-19. En ligne : https://doi.org/10.1002/aur.2959 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

The prevalence and developmental course of auditory processing differences in autistic children / Bonnie K. LAU in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1413-1424 Titre : The prevalence and developmental course of auditory processing differences in autistic children Type de document : Texte imprimé et/ou numérique Auteurs : Bonnie K. LAU, Auteur ; Katherine A. EMMONS, Auteur ; Adrian K. C. LEE, Auteur ; Jeff MUNSON, Auteur ; Stephen R. DAGER, Auteur ; Annette M. ESTES, Auteur Article en page(s) : p.1413-1424 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Auditory processing differences, including hyper- or hyposensitivity to sound, aversions to sound, and difficulty listening under noisy, real-world conditions, are commonly reported in autistic individuals. However, the developmental course and functional impact of these auditory processing differences are unclear. In this study, we investigate the prevalence, developmental trajectory, and functional impact of auditory processing differences in autistic children throughout childhood using a longitudinal study design. Auditory processing differences were measured using the Short Sensory Profile, a caregiver questionnaire, in addition to adaptive behaviors and disruptive/concerning behaviors at 3, 6, and 9?years of age. Our results showed that auditory processing differences were reported in greater than 70% of the autistic children in our sample at all three timepoints, maintained a high prevalence through 9?years of age, and were associated with increased disruptive/concerning behaviors and difficulty with adaptive behaviors. Furthermore, in our sample of children, auditory processing differences at age 3?years predicted disruptive/concerning behaviors and difficulty with adaptive behaviors at age 9?years. These findings warrant further investigations of the potential benefit of incorporating measures of auditory processing during routine clinical evaluations as well as interventions targeting auditory processing differences in autistic children. En ligne : https://doi.org/10.1002/aur.2961 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] The prevalence and developmental course of auditory processing differences in autistic children [Texte imprimé et/ou numérique] / Bonnie K. LAU, Auteur ; Katherine A. EMMONS, Auteur ; Adrian K. C. LEE, Auteur ; Jeff MUNSON, Auteur ; Stephen R. DAGER, Auteur ; Annette M. ESTES, Auteur . - p.1413-1424. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1413-1424 Index. décimale : PER Périodiques Résumé : Abstract Auditory processing differences, including hyper- or hyposensitivity to sound, aversions to sound, and difficulty listening under noisy, real-world conditions, are commonly reported in autistic individuals. However, the developmental course and functional impact of these auditory processing differences are unclear. In this study, we investigate the prevalence, developmental trajectory, and functional impact of auditory processing differences in autistic children throughout childhood using a longitudinal study design. Auditory processing differences were measured using the Short Sensory Profile, a caregiver questionnaire, in addition to adaptive behaviors and disruptive/concerning behaviors at 3, 6, and 9?years of age. Our results showed that auditory processing differences were reported in greater than 70% of the autistic children in our sample at all three timepoints, maintained a high prevalence through 9?years of age, and were associated with increased disruptive/concerning behaviors and difficulty with adaptive behaviors. Furthermore, in our sample of children, auditory processing differences at age 3?years predicted disruptive/concerning behaviors and difficulty with adaptive behaviors at age 9?years. These findings warrant further investigations of the potential benefit of incorporating measures of auditory processing during routine clinical evaluations as well as interventions targeting auditory processing differences in autistic children. En ligne : https://doi.org/10.1002/aur.2961 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Anxiety, depression, and well-being in autistic adults and adults with other developmental disabilities: A longitudinal cross-lagged analysis / Hillary SCHILTZ in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1425-1436 Titre : Anxiety, depression, and well-being in autistic adults and adults with other developmental disabilities: A longitudinal cross-lagged analysis Type de document : Texte imprimé et/ou numérique Auteurs : Hillary SCHILTZ, Auteur ; Kyle STERRETT, Auteur ; Hannah SINGER, Auteur ; Catherine LORD, Auteur Article en page(s) : p.1425-1436 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Autistic people and people with other developmental disabilities (DD) are at high likelihood for anxiety and depression, which can negatively affect adult life. Therefore, this study sought to understand temporal links between anxiety and depression over time in autistic adults and adults with DDs, and how these conditions impact specific aspects of positive well-being. A sample of 130 adults with autism or other DDs and their caregivers were drawn from a longitudinal study. Participants complete measures of anxiety (Adult Manifest Anxiety Scale), depression (Beck Depression Inventory, 2nd Edition), and well-being (Scales of Psychological Well-Being). Cross-lagged panel analyses revealed significant autoregressive effects for anxiety and depressive symptoms over time, based on both caregiver and self-report (all p<0.01). Additionally, although findings differed across reporter, cross-lagged links between anxiety and depression emerged over time. Based on caregiver-report, anxiety symptoms predicted later depressive symptoms (p=0.002) but depressive symptoms did not predict later anxiety (p=0.10); the opposite pattern was identified for self-report. Aspects of positive well-being (purpose in life, self-acceptance, personal growth) demonstrated differential links with anxiety and depression (p=0.001-0.53). These findings highlight the utility of a transdiagnostic approach to mental health services for autistic adults and adults with DDs, and the need to monitor for anxious or depressive symptoms in autistic adults and adults with DDs presenting with depression or anxiety, respectively. En ligne : https://doi.org/10.1002/aur.2967 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Anxiety, depression, and well-being in autistic adults and adults with other developmental disabilities: A longitudinal cross-lagged analysis [Texte imprimé et/ou numérique] / Hillary SCHILTZ, Auteur ; Kyle STERRETT, Auteur ; Hannah SINGER, Auteur ; Catherine LORD, Auteur . - p.1425-1436. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1425-1436 Index. décimale : PER Périodiques Résumé : Abstract Autistic people and people with other developmental disabilities (DD) are at high likelihood for anxiety and depression, which can negatively affect adult life. Therefore, this study sought to understand temporal links between anxiety and depression over time in autistic adults and adults with DDs, and how these conditions impact specific aspects of positive well-being. A sample of 130 adults with autism or other DDs and their caregivers were drawn from a longitudinal study. Participants complete measures of anxiety (Adult Manifest Anxiety Scale), depression (Beck Depression Inventory, 2nd Edition), and well-being (Scales of Psychological Well-Being). Cross-lagged panel analyses revealed significant autoregressive effects for anxiety and depressive symptoms over time, based on both caregiver and self-report (all p<0.01). Additionally, although findings differed across reporter, cross-lagged links between anxiety and depression emerged over time. Based on caregiver-report, anxiety symptoms predicted later depressive symptoms (p=0.002) but depressive symptoms did not predict later anxiety (p=0.10); the opposite pattern was identified for self-report. Aspects of positive well-being (purpose in life, self-acceptance, personal growth) demonstrated differential links with anxiety and depression (p=0.001-0.53). These findings highlight the utility of a transdiagnostic approach to mental health services for autistic adults and adults with DDs, and the need to monitor for anxious or depressive symptoms in autistic adults and adults with DDs presenting with depression or anxiety, respectively. En ligne : https://doi.org/10.1002/aur.2967 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Health conditions in autism: Defining the trajectory from adolescence to early adulthood / Beth A. MALOW in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1437-1449 Titre : Health conditions in autism: Defining the trajectory from adolescence to early adulthood Type de document : Texte imprimé et/ou numérique Auteurs : Beth A. MALOW, Auteur ; Yinge QIAN, Auteur ; Jennifer L. AMES, Auteur ; Stacey ALEXEEFF, Auteur ; Lisa A. CROEN, Auteur Article en page(s) : p.1437-1449 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Autistic adults, as compared to non-autistic adults, have increased rates of nearly all medical and psychiatric conditions. Many of these conditions begin in childhood, although few longitudinal studies have been conducted to examine prevalence rates of these conditions from adolescence into early adulthood. In this study, we analyze the longitudinal trajectory of health conditions in autistic youth, compared to age and sex-matched non-autistic youth, transitioning from adolescence into early adulthood in a large integrated health care delivery system. The percent and modeled prevalence of common medical and psychiatric conditions increased from age 14 to 22?years, with autistic youth having a higher prevalence of most conditions than non-autistic youth. The most prevalent conditions in autistic youth at all ages were obesity, neurological disorders, anxiety, and ADHD. The prevalence of obesity and dyslipidemia rose at a faster rate in autistic youth compared to non-autistic youth. By age 22, autistic females showed a higher prevalence of all medical and psychiatric conditions compared to autistic males. Our findings emphasize the importance of screening for medical and psychiatric conditions in autistic youth, coupled with health education targeted at this population, to mitigate the development of adverse health outcomes in autistic adults. En ligne : https://doi.org/10.1002/aur.2960 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Health conditions in autism: Defining the trajectory from adolescence to early adulthood [Texte imprimé et/ou numérique] / Beth A. MALOW, Auteur ; Yinge QIAN, Auteur ; Jennifer L. AMES, Auteur ; Stacey ALEXEEFF, Auteur ; Lisa A. CROEN, Auteur . - p.1437-1449. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1437-1449 Index. décimale : PER Périodiques Résumé : Abstract Autistic adults, as compared to non-autistic adults, have increased rates of nearly all medical and psychiatric conditions. Many of these conditions begin in childhood, although few longitudinal studies have been conducted to examine prevalence rates of these conditions from adolescence into early adulthood. In this study, we analyze the longitudinal trajectory of health conditions in autistic youth, compared to age and sex-matched non-autistic youth, transitioning from adolescence into early adulthood in a large integrated health care delivery system. The percent and modeled prevalence of common medical and psychiatric conditions increased from age 14 to 22?years, with autistic youth having a higher prevalence of most conditions than non-autistic youth. The most prevalent conditions in autistic youth at all ages were obesity, neurological disorders, anxiety, and ADHD. The prevalence of obesity and dyslipidemia rose at a faster rate in autistic youth compared to non-autistic youth. By age 22, autistic females showed a higher prevalence of all medical and psychiatric conditions compared to autistic males. Our findings emphasize the importance of screening for medical and psychiatric conditions in autistic youth, coupled with health education targeted at this population, to mitigate the development of adverse health outcomes in autistic adults. En ligne : https://doi.org/10.1002/aur.2960 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

A randomized parent-mediated physical activity intervention for autistic children / Laura A. PRIETO in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1450-1461 Titre : A randomized parent-mediated physical activity intervention for autistic children Type de document : Texte imprimé et/ou numérique Auteurs : Laura A. PRIETO, Auteur ; Benazir MEERA, Auteur ; Ashlyn BARRY, Auteur ; Gayatri SWARUP, Auteur ; Jennifer ASMUS, Auteur ; Byungmo KU, Auteur ; Kristi ROTH, Auteur ; John T. FOLEY, Auteur ; Luis COLUMNA, Auteur Article en page(s) : p.1450-1461 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract The purpose of this study was to examine the immediate and post effects of a parent-mediated physical activity intervention on the fundamental motor skills of autistic children. We randomly assigned parent-child dyads (n=31) of autistic children aged 4-11?years into three groups (workshop, an online, or control group). Each dyad participated in a 12-week intervention and was given adapted physical activity equipment and over 200 activities via a mobile application. Children were tested at the start and end of the intervention. The effect size (Cohen's d) of the control group for pre-post locomotor and ball skill scores were 0.12 and 0.06, respectively, indicating small effect size. The effect size of the online group for pre-post locomotor and ball skill scores were 49 and 0.26, respectively, indicating medium and small effect sizes. The effect size of the in-person group for pre-post locomotor and ball skill scores were 1.18 and 0.82, respectively, indicating large effect sizes. The outcomes of this physical activity intervention suggest that parents may facilitate the acquisition of fundamental motor skills of their autistic children. Although these results are positive, there is a need to further identify effective interventions for fundamental motor skill development in autistic children. Clinical Trials ID: NCT05159102. En ligne : https://doi.org/10.1002/aur.2969 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] A randomized parent-mediated physical activity intervention for autistic children [Texte imprimé et/ou numérique] / Laura A. PRIETO, Auteur ; Benazir MEERA, Auteur ; Ashlyn BARRY, Auteur ; Gayatri SWARUP, Auteur ; Jennifer ASMUS, Auteur ; Byungmo KU, Auteur ; Kristi ROTH, Auteur ; John T. FOLEY, Auteur ; Luis COLUMNA, Auteur . - p.1450-1461. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1450-1461 Index. décimale : PER Périodiques Résumé : Abstract The purpose of this study was to examine the immediate and post effects of a parent-mediated physical activity intervention on the fundamental motor skills of autistic children. We randomly assigned parent-child dyads (n=31) of autistic children aged 4-11?years into three groups (workshop, an online, or control group). Each dyad participated in a 12-week intervention and was given adapted physical activity equipment and over 200 activities via a mobile application. Children were tested at the start and end of the intervention. The effect size (Cohen's d) of the control group for pre-post locomotor and ball skill scores were 0.12 and 0.06, respectively, indicating small effect size. The effect size of the online group for pre-post locomotor and ball skill scores were 49 and 0.26, respectively, indicating medium and small effect sizes. The effect size of the in-person group for pre-post locomotor and ball skill scores were 1.18 and 0.82, respectively, indicating large effect sizes. The outcomes of this physical activity intervention suggest that parents may facilitate the acquisition of fundamental motor skills of their autistic children. Although these results are positive, there is a need to further identify effective interventions for fundamental motor skill development in autistic children. Clinical Trials ID: NCT05159102. En ligne : https://doi.org/10.1002/aur.2969 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Medical service utilization and costs of autism spectrum disorder: Evidence from hospital records in Beijing, China / Yanan ZHAO in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1462-1474 Titre : Medical service utilization and costs of autism spectrum disorder: Evidence from hospital records in Beijing, China Type de document : Texte imprimé et/ou numérique Auteurs : Yanan ZHAO, Auteur ; Binbin SU, Auteur ; Dawei ZHU, Auteur ; Xiaolong GUAN, Auteur ; Ruoxi DING, Auteur ; Dan GUO, Auteur ; Feng LU, Auteur ; Ping HE, Auteur Article en page(s) : p.1462-1474 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract As more and more people are diagnosed with autism spectrum disorder (ASD), it is necessary to better understand their costs. Detailed information on medical service utilization and costs could aid in designing equitable, effective policies to support individuals with ASD and their families. In this retrospective analysis, individuals with a hospital encounter (outpatient visit or inpatient admission) were collected from Beijing Municipal Health Big Data and Policy Research Center (BMHBD), from January 1, 2017 to December 31, 2021. We analyzed the costs, hospital visits/admissions and their changing trends over 5?years. Poisson regression and logit regression were conducted to analyze the influencing factors of visits, admissions and costs. The study population consisted of 26,826 users of medical services (26,583 outpatients and 243 inpatients; mean age: 4.82?+?3.47?years for outpatients; 11.62?+?6.74?years for inpatients). 99.1% were outpatients (mean?+?standard deviation (SD) costs per year: $422.06?+?$11.89), while 0.9% were inpatients (mean?+?SD costs per year: $4411.71?+?$925.81). More than 50% of outpatients received medication and diagnostic testing services. Among those with an inpatient admission, 91% received treatment services. Medication costs were the major contributor to medical costs for adults. Diagnostic test and treatment costs were the major contributors for children and adolescents. The findings demonstrated a significant economic burden for those diagnosed with ASD and highlighted opportunities for improving the care of this vulnerable group. This study adds to the literature by focusing on age differences among health-care utilization in individuals with ASD. En ligne : https://doi.org/10.1002/aur.2970 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Medical service utilization and costs of autism spectrum disorder: Evidence from hospital records in Beijing, China [Texte imprimé et/ou numérique] / Yanan ZHAO, Auteur ; Binbin SU, Auteur ; Dawei ZHU, Auteur ; Xiaolong GUAN, Auteur ; Ruoxi DING, Auteur ; Dan GUO, Auteur ; Feng LU, Auteur ; Ping HE, Auteur . - p.1462-1474. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1462-1474 Index. décimale : PER Périodiques Résumé : Abstract As more and more people are diagnosed with autism spectrum disorder (ASD), it is necessary to better understand their costs. Detailed information on medical service utilization and costs could aid in designing equitable, effective policies to support individuals with ASD and their families. In this retrospective analysis, individuals with a hospital encounter (outpatient visit or inpatient admission) were collected from Beijing Municipal Health Big Data and Policy Research Center (BMHBD), from January 1, 2017 to December 31, 2021. We analyzed the costs, hospital visits/admissions and their changing trends over 5?years. Poisson regression and logit regression were conducted to analyze the influencing factors of visits, admissions and costs. The study population consisted of 26,826 users of medical services (26,583 outpatients and 243 inpatients; mean age: 4.82?+?3.47?years for outpatients; 11.62?+?6.74?years for inpatients). 99.1% were outpatients (mean?+?standard deviation (SD) costs per year: $422.06?+?$11.89), while 0.9% were inpatients (mean?+?SD costs per year: $4411.71?+?$925.81). More than 50% of outpatients received medication and diagnostic testing services. Among those with an inpatient admission, 91% received treatment services. Medication costs were the major contributor to medical costs for adults. Diagnostic test and treatment costs were the major contributors for children and adolescents. The findings demonstrated a significant economic burden for those diagnosed with ASD and highlighted opportunities for improving the care of this vulnerable group. This study adds to the literature by focusing on age differences among health-care utilization in individuals with ASD. En ligne : https://doi.org/10.1002/aur.2970 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510