Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us? / Tim CADMAN in Autism Research, 8-5 (October 2015)  

Public ISBD [article]  inAutism Research > 8-5 (October 2015) . - p.477-485 Titre : Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us? Type de document : Texte imprimé et/ou numérique Auteurs : Tim CADMAN, Auteur ; Debbie SPAIN, Auteur ; Patrick JOHNSTON, Auteur ; Ailsa RUSSELL, Auteur ; David MATAIX-COLS, Auteur ; Michael C. CRAIG, Auteur ; Quinton DEELEY, Auteur ; Dene ROBERTSON, Auteur ; Clodagh M. MURPHY, Auteur ; Nicola GILLAN, Auteur ; C. Ellie WILSON, Auteur ; Maria MENDEZ, Auteur ; Christine ECKER, Auteur ; Eileen DALY, Auteur ; James FINDON, Auteur ; Karen GLASER, Auteur ; Mrc Aims CONSORTIUM, Auteur ; Francesca HAPPE, Auteur ; Declan MURPHY, Auteur Article en page(s) : p.477-485 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  adults  obsessive compulsive disorder  obsessive-compulsive inventory-revised  hoarding  self-report questionnaire Index. décimale : PER Périodiques Résumé : Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring OCD in ASD. We sought to describe the symptom profiles of adults with ASD, OCD, and ASD?+?OCD using the Obsessive Compulsive Inventory-Revised (OCI-R), and to assess the utility of the OCI-R as a screening measure in a high-functioning adult ASD sample. Individuals with ASD (n?=?171), OCD (n?=?108), ASD?+?OCD (n?=?54) and control participants (n?=?92) completed the OCI-R. Individuals with ASD?+?OCD reported significantly higher levels of obsessive-compulsive symptoms than those with ASD alone. OCD symptoms were not significantly correlated with core ASD repetitive behaviors as measured on the ADI-R or ADOS-G. The OCI-R showed good psychometric properties and corresponded well with clinician diagnosis of OCD. Receiver operating characteristic analysis suggested cut-offs for OCI-R Total and Checking scores that discriminated well between ASD?+?versus –OCD, and fairly well between ASD-alone and OCD-alone. OCD manifests separately from ASD and is characterized by a different profile of repetitive thoughts and behaviors. The OCI-R appears to be useful as a screening tool in the ASD adult population. Autism Res 2015, 8: 477–485. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1461 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270 [article] Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us? [Texte imprimé et/ou numérique] / Tim CADMAN, Auteur ; Debbie SPAIN, Auteur ; Patrick JOHNSTON, Auteur ; Ailsa RUSSELL, Auteur ; David MATAIX-COLS, Auteur ; Michael C. CRAIG, Auteur ; Quinton DEELEY, Auteur ; Dene ROBERTSON, Auteur ; Clodagh M. MURPHY, Auteur ; Nicola GILLAN, Auteur ; C. Ellie WILSON, Auteur ; Maria MENDEZ, Auteur ; Christine ECKER, Auteur ; Eileen DALY, Auteur ; James FINDON, Auteur ; Karen GLASER, Auteur ; Mrc Aims CONSORTIUM, Auteur ; Francesca HAPPE, Auteur ; Declan MURPHY, Auteur . - p.477-485. Langues : Anglais (eng) in Autism Research > 8-5 (October 2015) . - p.477-485 Mots-clés : autism spectrum disorder  adults  obsessive compulsive disorder  obsessive-compulsive inventory-revised  hoarding  self-report questionnaire Index. décimale : PER Périodiques Résumé : Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring OCD in ASD. We sought to describe the symptom profiles of adults with ASD, OCD, and ASD?+?OCD using the Obsessive Compulsive Inventory-Revised (OCI-R), and to assess the utility of the OCI-R as a screening measure in a high-functioning adult ASD sample. Individuals with ASD (n?=?171), OCD (n?=?108), ASD?+?OCD (n?=?54) and control participants (n?=?92) completed the OCI-R. Individuals with ASD?+?OCD reported significantly higher levels of obsessive-compulsive symptoms than those with ASD alone. OCD symptoms were not significantly correlated with core ASD repetitive behaviors as measured on the ADI-R or ADOS-G. The OCI-R showed good psychometric properties and corresponded well with clinician diagnosis of OCD. Receiver operating characteristic analysis suggested cut-offs for OCI-R Total and Checking scores that discriminated well between ASD?+?versus –OCD, and fairly well between ASD-alone and OCD-alone. OCD manifests separately from ASD and is characterized by a different profile of repetitive thoughts and behaviors. The OCI-R appears to be useful as a screening tool in the ASD adult population. Autism Res 2015, 8: 477–485. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1461 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270

Social anxiety in adult males with autism spectrum disorders / Debbie SPAIN in Research in Autism Spectrum Disorders, 32 (December 2016)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 32 (December 2016) . - p.13-23 Titre : Social anxiety in adult males with autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Debbie SPAIN, Auteur ; Francesca HAPPE, Auteur ; Patrick JOHNSTON, Auteur ; Malcolm CAMPBELL, Auteur ; Jacqueline SIN, Auteur ; Eileen DALY, Auteur ; Christine ECKER, Auteur ; Martin ANSON, Auteur ; Eddie CHAPLIN, Auteur ; Karen GLASER, Auteur ; Andreina MENDEZ, Auteur ; Karina LOVELL, Auteur ; Declan G. MURPHY, Auteur Article en page(s) : p.13-23 Langues : Anglais (eng) Mots-clés : Autism spectrum  Social anxiety  Social phobia  Adults  Self-report questionnaires Index. décimale : PER Périodiques Résumé : AbstractBackground Psychiatric conditions, notably anxiety, commonly co-occur with autism spectrum disorders (ASD). Method This study investigated self-reported behavioural, cognitive and affective symptoms of social anxiety (SA) in 50 adult males with ASD. Associations between SA, core ASD symptoms and facets of neuropsychological functioning were also examined. Results Twenty-six participants (52%) endorsed levels of SA that exceeded the suggested caseness threshold for social anxiety disorder. Categorical and dimensional data analyses indicated that there were no relationships between SA symptoms, present-state or childhood ASD symptom-severity, or measures of socio-emotional processing in this sample. Conclusions Study findings suggest that severity of SA is not merely a reflection of ASD symptom-severity. Further research is needed to ascertain the prevalence of SA in adult ASD epidemiological samples, and identify causal and maintaining mechanisms for these co-morbid symptoms. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.08.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=296 [article] Social anxiety in adult males with autism spectrum disorders [Texte imprimé et/ou numérique] / Debbie SPAIN, Auteur ; Francesca HAPPE, Auteur ; Patrick JOHNSTON, Auteur ; Malcolm CAMPBELL, Auteur ; Jacqueline SIN, Auteur ; Eileen DALY, Auteur ; Christine ECKER, Auteur ; Martin ANSON, Auteur ; Eddie CHAPLIN, Auteur ; Karen GLASER, Auteur ; Andreina MENDEZ, Auteur ; Karina LOVELL, Auteur ; Declan G. MURPHY, Auteur . - p.13-23. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 32 (December 2016) . - p.13-23 Mots-clés : Autism spectrum  Social anxiety  Social phobia  Adults  Self-report questionnaires Index. décimale : PER Périodiques Résumé : AbstractBackground Psychiatric conditions, notably anxiety, commonly co-occur with autism spectrum disorders (ASD). Method This study investigated self-reported behavioural, cognitive and affective symptoms of social anxiety (SA) in 50 adult males with ASD. Associations between SA, core ASD symptoms and facets of neuropsychological functioning were also examined. Results Twenty-six participants (52%) endorsed levels of SA that exceeded the suggested caseness threshold for social anxiety disorder. Categorical and dimensional data analyses indicated that there were no relationships between SA symptoms, present-state or childhood ASD symptom-severity, or measures of socio-emotional processing in this sample. Conclusions Study findings suggest that severity of SA is not merely a reflection of ASD symptom-severity. Further research is needed to ascertain the prevalence of SA in adult ASD epidemiological samples, and identify causal and maintaining mechanisms for these co-morbid symptoms. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.08.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=296

The Neuropsychology of Male Adults With High-Functioning Autism or Asperger Syndrome / C. Ellie WILSON in Autism Research, 7-5 (October 2014)  

Public ISBD [article]  inAutism Research > 7-5 (October 2014) . - p.568-581 Titre : The Neuropsychology of Male Adults With High-Functioning Autism or Asperger Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : C. Ellie WILSON, Auteur ; Francesca HAPPE, Auteur ; Sally J. WHEELWRIGHT, Auteur ; Christine ECKER, Auteur ; Michael V. LOMBARDO, Auteur ; Patrick JOHNSTON, Auteur ; Eileen DALY, Auteur ; Clodagh M. MURPHY, Auteur ; Debbie SPAIN, Auteur ; Meng-Chuan LAI, Auteur ; Bhismadev CHAKRABARTI, Auteur ; Disa A. SAUTER, Auteur ; CONSORTIUM MRC AIMS,, Auteur ; Simon BARON-COHEN, Auteur ; Declan G. M. MURPHY, Auteur Article en page(s) : p.568-581 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  cognitive profiles  autistic symptomatology  comorbid psychopathology  support vector machine classification  autistic subtypes Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is diagnosed on the basis of behavioral symptoms, but cognitive abilities may also be useful in characterizing individuals with ASD. One hundred seventy-eight high-functioning male adults, half with ASD and half without, completed tasks assessing IQ, a broad range of cognitive skills, and autistic and comorbid symptomatology. The aims of the study were, first, to determine whether significant differences existed between cases and controls on cognitive tasks, and whether cognitive profiles, derived using a multivariate classification method with data from multiple cognitive tasks, could distinguish between the two groups. Second, to establish whether cognitive skill level was correlated with degree of autistic symptom severity, and third, whether cognitive skill level was correlated with degree of comorbid psychopathology. Fourth, cognitive characteristics of individuals with Asperger Syndrome (AS) and high-functioning autism (HFA) were compared. After controlling for IQ, ASD and control groups scored significantly differently on tasks of social cognition, motor performance, and executive function (P's??0.05). To investigate cognitive profiles, 12 variables were entered into a support vector machine (SVM), which achieved good classification accuracy (81%) at a level significantly better than chance (P??0.0001). After correcting for multiple correlations, there were no significant associations between cognitive performance and severity of either autistic or comorbid symptomatology. There were no significant differences between AS and HFA groups on the cognitive tasks. Cognitive classification models could be a useful aid to the diagnostic process when used in conjunction with other data sources—including clinical history. Autism Res 2014, 7: 568–581. © 2014 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1394 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 [article] The Neuropsychology of Male Adults With High-Functioning Autism or Asperger Syndrome [Texte imprimé et/ou numérique] / C. Ellie WILSON, Auteur ; Francesca HAPPE, Auteur ; Sally J. WHEELWRIGHT, Auteur ; Christine ECKER, Auteur ; Michael V. LOMBARDO, Auteur ; Patrick JOHNSTON, Auteur ; Eileen DALY, Auteur ; Clodagh M. MURPHY, Auteur ; Debbie SPAIN, Auteur ; Meng-Chuan LAI, Auteur ; Bhismadev CHAKRABARTI, Auteur ; Disa A. SAUTER, Auteur ; CONSORTIUM MRC AIMS,, Auteur ; Simon BARON-COHEN, Auteur ; Declan G. M. MURPHY, Auteur . - p.568-581. Langues : Anglais (eng) in Autism Research > 7-5 (October 2014) . - p.568-581 Mots-clés : autism spectrum disorder  cognitive profiles  autistic symptomatology  comorbid psychopathology  support vector machine classification  autistic subtypes Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is diagnosed on the basis of behavioral symptoms, but cognitive abilities may also be useful in characterizing individuals with ASD. One hundred seventy-eight high-functioning male adults, half with ASD and half without, completed tasks assessing IQ, a broad range of cognitive skills, and autistic and comorbid symptomatology. The aims of the study were, first, to determine whether significant differences existed between cases and controls on cognitive tasks, and whether cognitive profiles, derived using a multivariate classification method with data from multiple cognitive tasks, could distinguish between the two groups. Second, to establish whether cognitive skill level was correlated with degree of autistic symptom severity, and third, whether cognitive skill level was correlated with degree of comorbid psychopathology. Fourth, cognitive characteristics of individuals with Asperger Syndrome (AS) and high-functioning autism (HFA) were compared. After controlling for IQ, ASD and control groups scored significantly differently on tasks of social cognition, motor performance, and executive function (P's??0.05). To investigate cognitive profiles, 12 variables were entered into a support vector machine (SVM), which achieved good classification accuracy (81%) at a level significantly better than chance (P??0.0001). After correcting for multiple correlations, there were no significant associations between cognitive performance and severity of either autistic or comorbid symptomatology. There were no significant differences between AS and HFA groups on the cognitive tasks. Cognitive classification models could be a useful aid to the diagnostic process when used in conjunction with other data sources—including clinical history. Autism Res 2014, 7: 568–581. © 2014 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1394 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241

---

1 (1 - 3 / 3)