Cardiac Reactivity and Stimulant Use in Adolescents with Autism Spectrum Disorders with Comorbid ADHD Versus ADHD / Marleen BINK in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.481-494 Titre : Cardiac Reactivity and Stimulant Use in Adolescents with Autism Spectrum Disorders with Comorbid ADHD Versus ADHD Type de document : Texte imprimé et/ou numérique Auteurs : Marleen BINK, Auteur ; A. POPMA, Auteur ; Ilja L. BONGERS, Auteur ; G. J. M. VAN BOXTEL, Auteur ; A. DENISSEN, Auteur ; Ch. VAN NIEUWENHUIZEN, Auteur Article en page(s) : p.481-494 Langues : Anglais (eng) Mots-clés : Cardiac adaptation  HRV  ASD  ADHD  Stimulant medication Index. décimale : PER Périodiques Résumé : A large number of youngsters with autism spectrum disorders (ASD) display comorbid attention deficit/hyperactivity disorder (ADHD) symptoms. However, previous studies are not conclusive whether psychophysiological correlates, like cardiac reactivity, are different for ASD with comorbid ADHD (ASD+) compared to ADHD. Therefore, the current study investigated (dis)similarities in cardiac reactivity and attention task performance. In a clinical sample, adolescents diagnosed with ASD+ (n = 20) versus ADHD (n = 36) and stimulant medication use (56 %) were compared during a baseline with eyes closed and task performance. Results for cardiac reactivity were similar for both diagnostic groups. Stimulant-medicated adolescents showed decreased adaptation of LF/HF ratio and faster reaction times than stimulant-free adolescents. The current study underlines the psychophysiological overlap of ADHD symptoms in adolescents with ASD+ and adolescents with ADHD. En ligne : http://dx.doi.org/10.1007/s10803-013-1929-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Cardiac Reactivity and Stimulant Use in Adolescents with Autism Spectrum Disorders with Comorbid ADHD Versus ADHD [Texte imprimé et/ou numérique] / Marleen BINK, Auteur ; A. POPMA, Auteur ; Ilja L. BONGERS, Auteur ; G. J. M. VAN BOXTEL, Auteur ; A. DENISSEN, Auteur ; Ch. VAN NIEUWENHUIZEN, Auteur . - p.481-494. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.481-494 Mots-clés : Cardiac adaptation  HRV  ASD  ADHD  Stimulant medication Index. décimale : PER Périodiques Résumé : A large number of youngsters with autism spectrum disorders (ASD) display comorbid attention deficit/hyperactivity disorder (ADHD) symptoms. However, previous studies are not conclusive whether psychophysiological correlates, like cardiac reactivity, are different for ASD with comorbid ADHD (ASD+) compared to ADHD. Therefore, the current study investigated (dis)similarities in cardiac reactivity and attention task performance. In a clinical sample, adolescents diagnosed with ASD+ (n = 20) versus ADHD (n = 36) and stimulant medication use (56 %) were compared during a baseline with eyes closed and task performance. Results for cardiac reactivity were similar for both diagnostic groups. Stimulant-medicated adolescents showed decreased adaptation of LF/HF ratio and faster reaction times than stimulant-free adolescents. The current study underlines the psychophysiological overlap of ADHD symptoms in adolescents with ASD+ and adolescents with ADHD. En ligne : http://dx.doi.org/10.1007/s10803-013-1929-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Gender Variance and the Autism Spectrum: An Examination of Children Ages 6-12 Years / A. N. NABBIJOHN in Journal of Autism and Developmental Disorders, 49-4 (April 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1570-1585 Titre : Gender Variance and the Autism Spectrum: An Examination of Children Ages 6-12 Years Type de document : Texte imprimé et/ou numérique Auteurs : A. N. NABBIJOHN, Auteur ; A. I. R. VAN DER MIESEN, Auteur ; A. SANTAROSSA, Auteur ; D. PERAGINE, Auteur ; A. L. C. DE VRIES, Auteur ; A. POPMA, Auteur ; Meng-Chuan LAI, Auteur ; D. P. VANDERLAAN, Auteur Article en page(s) : p.1570-1585 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Gender dysphoria  Gender variance  Oppositional defiant disorder  Sensory processing disorder Index. décimale : PER Périodiques Résumé : Gender variance (GV) and autism spectrum disorder (ASD) frequently co-occur in clinical populations. We investigated GV in association with ASD characteristics in nonclinical children and in children with developmental/mental health diagnoses. In 6-12-year-olds (N = 2445; 51% birth-assigned boys), the Gender Identity Questionnaire for Children measured GV and the Children's Social Behavior Questionnaire measured six subdomains of ASD characteristics. Among nonclinical children, GV was associated with parent-reported difficulties orienting socially and stereotyped behaviors. GV was also associated with parent-reported clinical diagnoses of ASD, sensory processing disorder, and oppositional defiant disorder. These findings suggest associations between specific ASD characteristics and GV in nonclinical children. Also, childhood GV should be further examined in a range of clinical populations, including ASD individuals. En ligne : https://dx.doi.org/10.1007/s10803-018-3843-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388 [article] Gender Variance and the Autism Spectrum: An Examination of Children Ages 6-12 Years [Texte imprimé et/ou numérique] / A. N. NABBIJOHN, Auteur ; A. I. R. VAN DER MIESEN, Auteur ; A. SANTAROSSA, Auteur ; D. PERAGINE, Auteur ; A. L. C. DE VRIES, Auteur ; A. POPMA, Auteur ; Meng-Chuan LAI, Auteur ; D. P. VANDERLAAN, Auteur . - p.1570-1585. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1570-1585 Mots-clés : Autism spectrum disorder  Gender dysphoria  Gender variance  Oppositional defiant disorder  Sensory processing disorder Index. décimale : PER Périodiques Résumé : Gender variance (GV) and autism spectrum disorder (ASD) frequently co-occur in clinical populations. We investigated GV in association with ASD characteristics in nonclinical children and in children with developmental/mental health diagnoses. In 6-12-year-olds (N = 2445; 51% birth-assigned boys), the Gender Identity Questionnaire for Children measured GV and the Children's Social Behavior Questionnaire measured six subdomains of ASD characteristics. Among nonclinical children, GV was associated with parent-reported difficulties orienting socially and stereotyped behaviors. GV was also associated with parent-reported clinical diagnoses of ASD, sensory processing disorder, and oppositional defiant disorder. These findings suggest associations between specific ASD characteristics and GV in nonclinical children. Also, childhood GV should be further examined in a range of clinical populations, including ASD individuals. En ligne : https://dx.doi.org/10.1007/s10803-018-3843-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388

Sex differences in psychiatric comorbidity and clinical presentation in youths with conduct disorder / K. KONRAD in Journal of Child Psychology and Psychiatry, 63-2 (February 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-2 (February 2022) . - p.218-228 Titre : Sex differences in psychiatric comorbidity and clinical presentation in youths with conduct disorder Type de document : Texte imprimé et/ou numérique Auteurs : K. KONRAD, Auteur ; G. KOHLS, Auteur ; S. BAUMANN, Auteur ; A. BERNHARD, Auteur ; A. MARTINELLI, Auteur ; Katharina ACKERMANN, Auteur ; A. SMARAGDI, Auteur ; K. GONZALEZ-MADRUGA, Auteur ; A. WELLS, Auteur ; J. C. ROGERS, Auteur ; R. PAULI, Auteur ; R. CLANTON, Auteur ; R. BAKER, Auteur ; L. KERSTEN, Auteur ; M. PRÄTZLICH, Auteur ; H. OLDENHOF, Auteur ; L. JANSEN, Auteur ; A. KLEEVEN, Auteur ; Aitana BIGORRA, Auteur ; A. HERVAS, Auteur ; I. KEREXETA-LIZEAGA, Auteur ; E. SESMA-PARDO, Auteur ; M. ANGEL GONZALEZ-TORRES, Auteur ; R. SIKLÓSI, Auteur ; R. DOCHNAL, Auteur ; Z. KALOGERAKIS, Auteur ; M. PIRLYMPOU, Auteur ; L. PAPADAKOS, Auteur ; H. CORNWELL, Auteur ; W. SCHARKE, Auteur ; Dimitris DIKEOS, Auteur ; A. FERNÁNDEZ-RIVAS, Auteur ; A. POPMA, Auteur ; C. STADLER, Auteur ; B. HERPERTZ-DAHLMANN, Auteur ; Stephane A. DE BRITO, Auteur ; G. FAIRCHILD, Auteur ; C. M. FREITAG, Auteur Article en page(s) : p.218-228 Langues : Anglais (eng) Mots-clés : Conduct disorder  callous-unemotional traits  psychiatric comorbidity  sex differences Index. décimale : PER Périodiques Résumé : BACKGROUND: Conduct disorder (CD) rarely occurs alone but is typically accompanied by comorbid psychiatric disorders, which complicates the clinical presentation and treatment of affected youths. The aim of this study was to investigate sex differences in comorbidity pattern in CD and to systematically explore the 'gender paradox' and 'delayed-onset pathway' hypotheses of female CD. METHODS: As part of the FemNAT-CD multisite study, semistructured clinical interviews and rating scales were used to perform a comprehensive phenotypic characterization of 454 girls and 295 boys with CD (9-18?years), compared to 864 sex- and age-matched typically developing controls. RESULTS: Girls with CD exhibited higher rates of current major depression, anxiety disorders, post-traumatic stress disorder and borderline personality disorder, whereas boys with CD had higher rates of current attention-deficit/hyperactivity disorder. In line with the 'gender paradox' hypothesis, relative to boys, girls with CD showed significantly more lifetime psychiatric comorbidities (incl. Alcohol Use Disorder), which were accompanied by more severe CD symptoms. Female and male youths with CD also differed significantly in their CD symptom profiles and distribution of age-of-onset subtypes of CD (i.e. fewer girls with childhood-onset CD). In line with the 'delayed-onset pathway' hypothesis, girls with adolescent-onset CD showed similar levels of dimensional psychopathology like boys with childhood-onset CD, while boys with adolescent-onset CD had the lowest levels of internalizing psychopathology. CONCLUSIONS: Within the largest study of CD in girls performed to date, we found compelling evidence for sex differences in comorbidity patterns and clinical presentation of CD. Our findings further support aspects of the 'gender paradox' and 'delayed-onset pathway' hypotheses by showing that girls with CD had higher rates of comorbid lifetime mental disorders and functional impairments, and they usually developed CD during adolescence. These novel data on sex-specific clinical profiles of CD will be critical in informing intervention and prevention programmes. En ligne : http://dx.doi.org/10.1111/jcpp.13428 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 [article] Sex differences in psychiatric comorbidity and clinical presentation in youths with conduct disorder [Texte imprimé et/ou numérique] / K. KONRAD, Auteur ; G. KOHLS, Auteur ; S. BAUMANN, Auteur ; A. BERNHARD, Auteur ; A. MARTINELLI, Auteur ; Katharina ACKERMANN, Auteur ; A. SMARAGDI, Auteur ; K. GONZALEZ-MADRUGA, Auteur ; A. WELLS, Auteur ; J. C. ROGERS, Auteur ; R. PAULI, Auteur ; R. CLANTON, Auteur ; R. BAKER, Auteur ; L. KERSTEN, Auteur ; M. PRÄTZLICH, Auteur ; H. OLDENHOF, Auteur ; L. JANSEN, Auteur ; A. KLEEVEN, Auteur ; Aitana BIGORRA, Auteur ; A. HERVAS, Auteur ; I. KEREXETA-LIZEAGA, Auteur ; E. SESMA-PARDO, Auteur ; M. ANGEL GONZALEZ-TORRES, Auteur ; R. SIKLÓSI, Auteur ; R. DOCHNAL, Auteur ; Z. KALOGERAKIS, Auteur ; M. PIRLYMPOU, Auteur ; L. PAPADAKOS, Auteur ; H. CORNWELL, Auteur ; W. SCHARKE, Auteur ; Dimitris DIKEOS, Auteur ; A. FERNÁNDEZ-RIVAS, Auteur ; A. POPMA, Auteur ; C. STADLER, Auteur ; B. HERPERTZ-DAHLMANN, Auteur ; Stephane A. DE BRITO, Auteur ; G. FAIRCHILD, Auteur ; C. M. FREITAG, Auteur . - p.218-228. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-2 (February 2022) . - p.218-228 Mots-clés : Conduct disorder  callous-unemotional traits  psychiatric comorbidity  sex differences Index. décimale : PER Périodiques Résumé : BACKGROUND: Conduct disorder (CD) rarely occurs alone but is typically accompanied by comorbid psychiatric disorders, which complicates the clinical presentation and treatment of affected youths. The aim of this study was to investigate sex differences in comorbidity pattern in CD and to systematically explore the 'gender paradox' and 'delayed-onset pathway' hypotheses of female CD. METHODS: As part of the FemNAT-CD multisite study, semistructured clinical interviews and rating scales were used to perform a comprehensive phenotypic characterization of 454 girls and 295 boys with CD (9-18?years), compared to 864 sex- and age-matched typically developing controls. RESULTS: Girls with CD exhibited higher rates of current major depression, anxiety disorders, post-traumatic stress disorder and borderline personality disorder, whereas boys with CD had higher rates of current attention-deficit/hyperactivity disorder. In line with the 'gender paradox' hypothesis, relative to boys, girls with CD showed significantly more lifetime psychiatric comorbidities (incl. Alcohol Use Disorder), which were accompanied by more severe CD symptoms. Female and male youths with CD also differed significantly in their CD symptom profiles and distribution of age-of-onset subtypes of CD (i.e. fewer girls with childhood-onset CD). In line with the 'delayed-onset pathway' hypothesis, girls with adolescent-onset CD showed similar levels of dimensional psychopathology like boys with childhood-onset CD, while boys with adolescent-onset CD had the lowest levels of internalizing psychopathology. CONCLUSIONS: Within the largest study of CD in girls performed to date, we found compelling evidence for sex differences in comorbidity patterns and clinical presentation of CD. Our findings further support aspects of the 'gender paradox' and 'delayed-onset pathway' hypotheses by showing that girls with CD had higher rates of comorbid lifetime mental disorders and functional impairments, and they usually developed CD during adolescence. These novel data on sex-specific clinical profiles of CD will be critical in informing intervention and prevention programmes. En ligne : http://dx.doi.org/10.1111/jcpp.13428 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457

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