Brainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism / Brittany G. TRAVERS in Journal of Autism and Developmental Disorders, 45-9 (September 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-9 (September 2015) . - p.3030-3040 Titre : Brainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Brittany G. TRAVERS, Auteur ; Erin D. BIGLER, Auteur ; Do P. M. TROMP, Auteur ; Nagesh ADLURU, Auteur ; Dan DESTICHE, Auteur ; Danica SAMSIN, Auteur ; Alyson FROEHLICH, Auteur ; Molly D. B. PRIGGE, Auteur ; Tyler C. DUFFIELD, Auteur ; Nicholas LANGE, Auteur ; Andrew L. ALEXANDER, Auteur ; Janet E. LAINHART, Auteur Article en page(s) : p.3030-3040 Langues : Anglais (eng) Mots-clés : Autism  Motor  Diffusion tensor imaging  Brainstem  Grip strength  Finger tapping Index. décimale : PER Périodiques Résumé : Mounting evidence suggests that poorer motor skills may be related to more severe autism symptoms. This study investigated if atypical white matter microstructure in the brain mediated the relationship between motor skills and ASD symptom severity. Sixty-seven males with ASD and 42 males with typical development (5–33 years old) completed a diffusion tensor imaging scan and measures of grip strength, finger tapping, and autism symptom severity. Within the ASD group, weaker grip strength predicted more severe autism symptoms. Fractional anisotropy of the brainstem’s corticospinal tract predicted both grip strength and autism symptom severity and mediated the relationship between the two. These findings suggest that brainstem white matter may contribute to autism symptoms and grip strength in ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2467-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267 [article] Brainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism [Texte imprimé et/ou numérique] / Brittany G. TRAVERS, Auteur ; Erin D. BIGLER, Auteur ; Do P. M. TROMP, Auteur ; Nagesh ADLURU, Auteur ; Dan DESTICHE, Auteur ; Danica SAMSIN, Auteur ; Alyson FROEHLICH, Auteur ; Molly D. B. PRIGGE, Auteur ; Tyler C. DUFFIELD, Auteur ; Nicholas LANGE, Auteur ; Andrew L. ALEXANDER, Auteur ; Janet E. LAINHART, Auteur . - p.3030-3040. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-9 (September 2015) . - p.3030-3040 Mots-clés : Autism  Motor  Diffusion tensor imaging  Brainstem  Grip strength  Finger tapping Index. décimale : PER Périodiques Résumé : Mounting evidence suggests that poorer motor skills may be related to more severe autism symptoms. This study investigated if atypical white matter microstructure in the brain mediated the relationship between motor skills and ASD symptom severity. Sixty-seven males with ASD and 42 males with typical development (5–33 years old) completed a diffusion tensor imaging scan and measures of grip strength, finger tapping, and autism symptom severity. Within the ASD group, weaker grip strength predicted more severe autism symptoms. Fractional anisotropy of the brainstem’s corticospinal tract predicted both grip strength and autism symptom severity and mediated the relationship between the two. These findings suggest that brainstem white matter may contribute to autism symptoms and grip strength in ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2467-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267

Longitudinal Stability of Intellectual Functioning in Autism Spectrum Disorder: From Age 3 Through Mid-adulthood / Molly B. D. PRIGGE in Journal of Autism and Developmental Disorders, 52-10 (October 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-10 (October 2022) . - p.4490-4504 Titre : Longitudinal Stability of Intellectual Functioning in Autism Spectrum Disorder: From Age 3 Through Mid-adulthood Type de document : Texte imprimé et/ou numérique Auteurs : Molly B. D. PRIGGE, Auteur ; Erin D. BIGLER, Auteur ; Nicholas LANGE, Auteur ; Jubel MORGAN, Auteur ; Alyson FROEHLICH, Auteur ; Abigail FREEMAN, Auteur ; Kristina KELLETT, Auteur ; Karen L. KANE, Auteur ; Carolyn K. KING, Auteur ; June TAYLOR, Auteur ; Douglas C. 3rd DEAN, Auteur ; Jace B. KING, Auteur ; Jeff S. ANDERSON, Auteur ; Brandon A. ZIELINSKI, Auteur ; Andrew L. ALEXANDER, Auteur ; Janet E. LAINHART, Auteur Article en page(s) : p.4490-4504 Langues : Anglais (eng) Mots-clés : Asd  Autism spectrum disorder  Cognitive development  Intelligence  Longitudinal study  Stability Index. décimale : PER Périodiques Résumé : Intelligence (IQ) scores are used in educational and vocational planning for individuals with autism spectrum disorder (ASD) yet little is known about the stability of IQ throughout development. We examined longitudinal age-related IQ stability in 119 individuals with ASD (3-36 years of age at first visit) and 128 typically developing controls. Intelligence measures were collected over a 20-year period. In ASD, Full Scale (FSIQ) and Verbal (VIQ) Intelligence started lower in childhood and increased at a greater rate with age relative to the control group. By early adulthood, VIQ and working memory stabilized, whereas nonverbal and perceptual scores continued to change. Our results suggest that in individuals with ASD, IQ estimates may be dynamic in childhood and young adulthood. En ligne : http://dx.doi.org/10.1007/s10803-021-05227-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Longitudinal Stability of Intellectual Functioning in Autism Spectrum Disorder: From Age 3 Through Mid-adulthood [Texte imprimé et/ou numérique] / Molly B. D. PRIGGE, Auteur ; Erin D. BIGLER, Auteur ; Nicholas LANGE, Auteur ; Jubel MORGAN, Auteur ; Alyson FROEHLICH, Auteur ; Abigail FREEMAN, Auteur ; Kristina KELLETT, Auteur ; Karen L. KANE, Auteur ; Carolyn K. KING, Auteur ; June TAYLOR, Auteur ; Douglas C. 3rd DEAN, Auteur ; Jace B. KING, Auteur ; Jeff S. ANDERSON, Auteur ; Brandon A. ZIELINSKI, Auteur ; Andrew L. ALEXANDER, Auteur ; Janet E. LAINHART, Auteur . - p.4490-4504. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-10 (October 2022) . - p.4490-4504 Mots-clés : Asd  Autism spectrum disorder  Cognitive development  Intelligence  Longitudinal study  Stability Index. décimale : PER Périodiques Résumé : Intelligence (IQ) scores are used in educational and vocational planning for individuals with autism spectrum disorder (ASD) yet little is known about the stability of IQ throughout development. We examined longitudinal age-related IQ stability in 119 individuals with ASD (3-36 years of age at first visit) and 128 typically developing controls. Intelligence measures were collected over a 20-year period. In ASD, Full Scale (FSIQ) and Verbal (VIQ) Intelligence started lower in childhood and increased at a greater rate with age relative to the control group. By early adulthood, VIQ and working memory stabilized, whereas nonverbal and perceptual scores continued to change. Our results suggest that in individuals with ASD, IQ estimates may be dynamic in childhood and young adulthood. En ligne : http://dx.doi.org/10.1007/s10803-021-05227-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

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