Antipsychotics in the Treatment of Autism / Carmem GOTTFRIED  

Public ISBD in Autism Spectrum Disorders - From Genes to Environment / Tim WILLIAMS Titre : Antipsychotics in the Treatment of Autism Type de document : texte imprimé Auteurs : Carmem GOTTFRIED, Auteur ; Rudimar RIESGO, Auteur Année de publication : 2011 Importance : p.23-46 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques En ligne : http://dx.doi.org/10.5772/18608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=143 in Autism Spectrum Disorders - From Genes to Environment / Tim WILLIAMS Antipsychotics in the Treatment of Autism [texte imprimé] / Carmem GOTTFRIED, Auteur ; Rudimar RIESGO, Auteur . - 2011 . - p.23-46. Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques En ligne : http://dx.doi.org/10.5772/18608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=143

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Effect of a ketogenic diet on autism spectrum disorder: A systematic review / Kamila CASTRO in Research in Autism Spectrum Disorders, 20 (December 2015)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 20 (December 2015) . - p.31-38 Titre : Effect of a ketogenic diet on autism spectrum disorder: A systematic review Type de document : texte imprimé Auteurs : Kamila CASTRO, Auteur ; Larissa Slongo FACCIOLI, Auteur ; Diego BARONIO, Auteur ; Carmem GOTTFRIED, Auteur ; Ingrid SCHWEIGERT PERRY, Auteur ; Rudimar DOS SANTOS RIESGO, Auteur Article en page(s) : p.31-38 Langues : Anglais (eng) Mots-clés : Autistic disorder  Ketogenic diet  Behavioural symptoms Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is primarily characterized by impaired social interaction and communication, as well as restricted repetitive behaviours and interests. The utilization of the ketogenic diet (KD) in different neurological disorders has become a valid approach over time, and recently, it has also been advocated as a potential therapeutic for ASD. A MEDLINE, Scopus and Cochrane search was performed by two independent reviewers to investigate the relationship between ASD and the KD in humans and experimental studies. Of the eighty-one potentially relevant articles, eight articles met the inclusion criteria: three studies with animals and five studies with humans. The consistency between reviewers was κ = 0.817. In humans, the studies mainly focused on the behavioural outcomes provided by this diet and reported ameliorated behavioural symptoms via an improved score in the Childhood Autism Rating Scale (CARS). The KD in prenatal valproic acid (VPA)-exposed rodents, as well as in BTBR and Mecp2 mice strains, resulted in an attenuation of some autistic-like features. The limited number of reports of improvements after treatment with the KD is insufficient to attest to the practicability of the KD as a treatment for ASD, but it is still a good indicator that this diet is a promising therapeutic option for this disorder. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.08.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270 [article] Effect of a ketogenic diet on autism spectrum disorder: A systematic review [texte imprimé] / Kamila CASTRO, Auteur ; Larissa Slongo FACCIOLI, Auteur ; Diego BARONIO, Auteur ; Carmem GOTTFRIED, Auteur ; Ingrid SCHWEIGERT PERRY, Auteur ; Rudimar DOS SANTOS RIESGO, Auteur . - p.31-38. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 20 (December 2015) . - p.31-38 Mots-clés : Autistic disorder  Ketogenic diet  Behavioural symptoms Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is primarily characterized by impaired social interaction and communication, as well as restricted repetitive behaviours and interests. The utilization of the ketogenic diet (KD) in different neurological disorders has become a valid approach over time, and recently, it has also been advocated as a potential therapeutic for ASD. A MEDLINE, Scopus and Cochrane search was performed by two independent reviewers to investigate the relationship between ASD and the KD in humans and experimental studies. Of the eighty-one potentially relevant articles, eight articles met the inclusion criteria: three studies with animals and five studies with humans. The consistency between reviewers was κ = 0.817. In humans, the studies mainly focused on the behavioural outcomes provided by this diet and reported ameliorated behavioural symptoms via an improved score in the Childhood Autism Rating Scale (CARS). The KD in prenatal valproic acid (VPA)-exposed rodents, as well as in BTBR and Mecp2 mice strains, resulted in an attenuation of some autistic-like features. The limited number of reports of improvements after treatment with the KD is insufficient to attest to the practicability of the KD as a treatment for ASD, but it is still a good indicator that this diet is a promising therapeutic option for this disorder. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.08.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270

Psychomotor agitation and mood instability in patients with autism spectrum disorders: A possible effect of SLC6A4 gene? / Jaqueline Bohrer SCHUCH in Research in Autism Spectrum Disorders, 26 (June 2016)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 26 (June 2016) . - p.48-56 Titre : Psychomotor agitation and mood instability in patients with autism spectrum disorders: A possible effect of SLC6A4 gene? Type de document : texte imprimé Auteurs : Jaqueline Bohrer SCHUCH, Auteur ; Diana MÃœLLER, Auteur ; Renata Giuliani ENDRES, Auteur ; Cleonice Alves BOSA, Auteur ; Dânae LONGO, Auteur ; Lavinia SCHULER-FACCINI, Auteur ; Josiane RANZAN, Auteur ; Michele Michelin BECKER, Auteur ; Rudimar DOS SANTOS RIESGO, Auteur ; Tatiana ROMAN, Auteur Article en page(s) : p.48-56 Langues : Anglais (eng) Mots-clés : ASD  Serotonin transporter gene  Clinical symptoms  Sex differences  Association  Family-based test Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are a group of neurodevelopmental conditions characterized by impairments in communication and social interaction and repetitive and stereotyped behaviors. Serotoninergic transmission has been suggested as an important neuronal pathway in ASD. In this study, we analyzed four polymorphisms (5HTTLPR, rs2066713, STin2, rs1042173; 5′ → 3′ end) at the serotonin transporter gene (SLC6A4) in a sample of 209 ASD children and their biological parents. Both single markers and haplotypes were tested for association with ASD diagnosis and with clinical symptoms (aggression, echolalia, seizures, mood instability, psychomotor agitation, repetitive behaviors and sleep disorders) commonly present in ASD patients. The family-based analyses showed a significant result for one haplotype (H4: S-G-12R-T), which did not hold in global analyses. In male patients, a nominal association between the rs1042173 GG genotype and a diminished psychomotor agitation was observed; a trend for an association between the 5HTTLPR LaLa genotype and mood instability was also verified. Through interesting results that are mainly related to clinical manifestations and gender differences, our study adds to knowledge of ASD. Future investigations may corroborate the relevance of our data to upcoming clinical and pharmacological interventions. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.03.001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285 [article] Psychomotor agitation and mood instability in patients with autism spectrum disorders: A possible effect of SLC6A4 gene? [texte imprimé] / Jaqueline Bohrer SCHUCH, Auteur ; Diana MÃœLLER, Auteur ; Renata Giuliani ENDRES, Auteur ; Cleonice Alves BOSA, Auteur ; Dânae LONGO, Auteur ; Lavinia SCHULER-FACCINI, Auteur ; Josiane RANZAN, Auteur ; Michele Michelin BECKER, Auteur ; Rudimar DOS SANTOS RIESGO, Auteur ; Tatiana ROMAN, Auteur . - p.48-56. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 26 (June 2016) . - p.48-56 Mots-clés : ASD  Serotonin transporter gene  Clinical symptoms  Sex differences  Association  Family-based test Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are a group of neurodevelopmental conditions characterized by impairments in communication and social interaction and repetitive and stereotyped behaviors. Serotoninergic transmission has been suggested as an important neuronal pathway in ASD. In this study, we analyzed four polymorphisms (5HTTLPR, rs2066713, STin2, rs1042173; 5′ → 3′ end) at the serotonin transporter gene (SLC6A4) in a sample of 209 ASD children and their biological parents. Both single markers and haplotypes were tested for association with ASD diagnosis and with clinical symptoms (aggression, echolalia, seizures, mood instability, psychomotor agitation, repetitive behaviors and sleep disorders) commonly present in ASD patients. The family-based analyses showed a significant result for one haplotype (H4: S-G-12R-T), which did not hold in global analyses. In male patients, a nominal association between the rs1042173 GG genotype and a diminished psychomotor agitation was observed; a trend for an association between the 5HTTLPR LaLa genotype and mood instability was also verified. Through interesting results that are mainly related to clinical manifestations and gender differences, our study adds to knowledge of ASD. Future investigations may corroborate the relevance of our data to upcoming clinical and pharmacological interventions. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.03.001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285

Validation of the Brief Autism Mealtime Behavior Inventory (BAMBI) Questionnaire / Kamila CASTRO in Journal of Autism and Developmental Disorders, 49-6 (June 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2536-2544 Titre : Validation of the Brief Autism Mealtime Behavior Inventory (BAMBI) Questionnaire Type de document : texte imprimé Auteurs : Kamila CASTRO, Auteur ; Ingrid SCHWEIGERT PERRY, Auteur ; Gabriela Pachecho FERREIRA, Auteur ; Josemar MARCHEZAN, Auteur ; Michele BECKER, Auteur ; Rudimar RIESGO, Auteur Article en page(s) : p.2536-2544 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Feeding behaviours  Nutrition Index. décimale : PER Périodiques Résumé : This study aims to translate the Brief Autism Mealtime Behaviour Inventory (BAMBI) questionnaire to Brazilian Portuguese, in order to provide a tool to be used in clinic routine that encourages the evaluation of the feeding behaviour of patients with Autism Spectrum Disorder (ASD). The final sample contained 410 participants, the mean age was 9.58 +/- 1.2 and the majority of participants were male (95%). Validation of this questionnaire allows a structured evaluation for this population to be integrated not only into the clinical routine but also to help parent's interventions about the eating problems and possible consequences. This is of utmost importance, since parents are reporting the nutritional aspects more often, and studies indicate that up to 80% of ASD patients may present feeding behavior problems. En ligne : https://dx.doi.org/10.1007/s10803-019-04006-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400 [article] Validation of the Brief Autism Mealtime Behavior Inventory (BAMBI) Questionnaire [texte imprimé] / Kamila CASTRO, Auteur ; Ingrid SCHWEIGERT PERRY, Auteur ; Gabriela Pachecho FERREIRA, Auteur ; Josemar MARCHEZAN, Auteur ; Michele BECKER, Auteur ; Rudimar RIESGO, Auteur . - p.2536-2544. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2536-2544 Mots-clés : Autism spectrum disorder  Feeding behaviours  Nutrition Index. décimale : PER Périodiques Résumé : This study aims to translate the Brief Autism Mealtime Behaviour Inventory (BAMBI) questionnaire to Brazilian Portuguese, in order to provide a tool to be used in clinic routine that encourages the evaluation of the feeding behaviour of patients with Autism Spectrum Disorder (ASD). The final sample contained 410 participants, the mean age was 9.58 +/- 1.2 and the majority of participants were male (95%). Validation of this questionnaire allows a structured evaluation for this population to be integrated not only into the clinical routine but also to help parent's interventions about the eating problems and possible consequences. This is of utmost importance, since parents are reporting the nutritional aspects more often, and studies indicate that up to 80% of ASD patients may present feeding behavior problems. En ligne : https://dx.doi.org/10.1007/s10803-019-04006-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400

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