Family history of immune conditions and autism spectrum and developmental disorders: Findings from the study to explore early development / Lisa A. CROEN in Autism Research, 12-1 (January 2019)  

Public ISBD [article]  inAutism Research > 12-1 (January 2019) . - p.123-135 Titre : Family history of immune conditions and autism spectrum and developmental disorders: Findings from the study to explore early development Type de document : texte imprimé Auteurs : Lisa A. CROEN, Auteur ; Yinge QIAN, Auteur ; Paul ASHWOOD, Auteur ; Julie L. DANIELS, Auteur ; M. Daniele FALLIN, Auteur ; Diana SCHENDEL, Auteur ; Laura A. SCHIEVE, Auteur ; Alison B. SINGER, Auteur ; Ousseny ZERBO, Auteur Article en page(s) : p.123-135 Langues : Anglais (eng) Mots-clés : allergy  asthma  autism  autoimmune  pregnancy  prenatal Index. décimale : PER Périodiques Résumé : Numerous studies have reported immune system disturbances in individuals with autism and their family members; however, there is considerable variability in findings with respect to the specific immune conditions involved, their timing, and the family members affected and little understanding of variation by autism subphenotype. Using data from the Study to Explore Early Development (SEED), a multi-site case-control study of children born 2003-2006 in the United States, we examined the role of family history of autoimmune diseases, asthma, and allergies in autism spectrum disorder (ASD) as well as other developmental disorders (DD). We investigated maternal immune conditions during the pregnancy period, as well as lifetime history of these conditions in several family members (mother, father, siblings, and study child). Logistic regression analyses included 663 children with ASD, 984 children with DD, and 915 controls ascertained from the general population (POP). Maternal history of eczema/psoriasis and asthma was associated with a 20%-40% increased odds of both ASD and DD. Risk estimates varied by specific ASD subphenotypes in association with these exposures. In addition, children with ASD were more likely to have a history of psoriasis/eczema or allergies than POP controls. No association was observed for paternal history or family history of these immune conditions for either ASD or DD. These data support a link between maternal and child immune conditions and adverse neurodevelopmental outcomes, and further suggest that associations may differ by ASD phenotype of the child. Autism Research 2019, 12: 123-135. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Using data from a large multi-site study in the US-the Study to Explore Early Development-we found that women with a history of eczema/psoriasis and asthma are more likely to have children with ASD or DD. In addition, children with ASD are more likely to have a history of psoriasis/eczema or allergies than typically developing children. These data support a link between maternal and child immune conditions and adverse neurodevelopmental outcomes. En ligne : http://dx.doi.org/10.1002/aur.1979 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376 [article] Family history of immune conditions and autism spectrum and developmental disorders: Findings from the study to explore early development [texte imprimé] / Lisa A. CROEN, Auteur ; Yinge QIAN, Auteur ; Paul ASHWOOD, Auteur ; Julie L. DANIELS, Auteur ; M. Daniele FALLIN, Auteur ; Diana SCHENDEL, Auteur ; Laura A. SCHIEVE, Auteur ; Alison B. SINGER, Auteur ; Ousseny ZERBO, Auteur . - p.123-135. Langues : Anglais (eng) in Autism Research > 12-1 (January 2019) . - p.123-135 Mots-clés : allergy  asthma  autism  autoimmune  pregnancy  prenatal Index. décimale : PER Périodiques Résumé : Numerous studies have reported immune system disturbances in individuals with autism and their family members; however, there is considerable variability in findings with respect to the specific immune conditions involved, their timing, and the family members affected and little understanding of variation by autism subphenotype. Using data from the Study to Explore Early Development (SEED), a multi-site case-control study of children born 2003-2006 in the United States, we examined the role of family history of autoimmune diseases, asthma, and allergies in autism spectrum disorder (ASD) as well as other developmental disorders (DD). We investigated maternal immune conditions during the pregnancy period, as well as lifetime history of these conditions in several family members (mother, father, siblings, and study child). Logistic regression analyses included 663 children with ASD, 984 children with DD, and 915 controls ascertained from the general population (POP). Maternal history of eczema/psoriasis and asthma was associated with a 20%-40% increased odds of both ASD and DD. Risk estimates varied by specific ASD subphenotypes in association with these exposures. In addition, children with ASD were more likely to have a history of psoriasis/eczema or allergies than POP controls. No association was observed for paternal history or family history of these immune conditions for either ASD or DD. These data support a link between maternal and child immune conditions and adverse neurodevelopmental outcomes, and further suggest that associations may differ by ASD phenotype of the child. Autism Research 2019, 12: 123-135. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Using data from a large multi-site study in the US-the Study to Explore Early Development-we found that women with a history of eczema/psoriasis and asthma are more likely to have children with ASD or DD. In addition, children with ASD are more likely to have a history of psoriasis/eczema or allergies than typically developing children. These data support a link between maternal and child immune conditions and adverse neurodevelopmental outcomes. En ligne : http://dx.doi.org/10.1002/aur.1979 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376

A full semantic toolbox is essential for autism research and practice to thrive / Alison SINGER in Autism Research, 16-3 (March 2023)  

Public ISBD [article]  inAutism Research > 16-3 (March 2023) . - p.497-501 Titre : A full semantic toolbox is essential for autism research and practice to thrive Type de document : texte imprimé Auteurs : Alison SINGER, Auteur ; Amy LUTZ, Auteur ; Jill ESCHER, Auteur ; Alycia K. HALLADAY, Auteur Article en page(s) : p.497-501 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Individuals diagnosed with autism spectrum disorder (ASD) present with a highly diverse set of challenges, disabilities, impairments and strengths. Recently, it has been suggested that researchers and practitioners avoid using certain words to describe the difficulties and impairments experienced by individuals with ASD to reduce stigma. The proposed limitations on terminology were developed by only a subset of the autism community, and the recommendations are already causing negative consequences that may be harmful to future scientific and clinical endeavors and, ultimately, to people with ASD. No one should have the power to censor language to exclude the observable realities of autism. Scientists and clinicians must be able to use any scientifically accurate terms necessary to describe the wide range of autistic people they study and support, without fear of censure or retribution. En ligne : https://doi.org/10.1002/aur.2876 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=498 [article] A full semantic toolbox is essential for autism research and practice to thrive [texte imprimé] / Alison SINGER, Auteur ; Amy LUTZ, Auteur ; Jill ESCHER, Auteur ; Alycia K. HALLADAY, Auteur . - p.497-501. Langues : Anglais (eng) in Autism Research > 16-3 (March 2023) . - p.497-501 Index. décimale : PER Périodiques Résumé : Abstract Individuals diagnosed with autism spectrum disorder (ASD) present with a highly diverse set of challenges, disabilities, impairments and strengths. Recently, it has been suggested that researchers and practitioners avoid using certain words to describe the difficulties and impairments experienced by individuals with ASD to reduce stigma. The proposed limitations on terminology were developed by only a subset of the autism community, and the recommendations are already causing negative consequences that may be harmful to future scientific and clinical endeavors and, ultimately, to people with ASD. No one should have the power to censor language to exclude the observable realities of autism. Scientists and clinicians must be able to use any scientifically accurate terms necessary to describe the wide range of autistic people they study and support, without fear of censure or retribution. En ligne : https://doi.org/10.1002/aur.2876 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=498

Maternal Exposure to Occupational Asthmagens During Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development / Alison B. SINGER in Journal of Autism and Developmental Disorders, 46-11 (November 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-11 (November 2016) . - p.3458-3468 Titre : Maternal Exposure to Occupational Asthmagens During Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development Type de document : texte imprimé Auteurs : Alison B. SINGER, Auteur ; Gayle C. WINDHAM, Auteur ; Lisa A. CROEN, Auteur ; Julie L. DANIELS, Auteur ; Brian K. LEE, Auteur ; Yinge QIAN, Auteur ; Diana SCHENDEL, Auteur ; M. Daniele FALLIN, Auteur ; Igor BURSTYN, Auteur Article en page(s) : p.3458-3468 Langues : Anglais (eng) Mots-clés : Autism  Maternal occupation  Exposure  Maternal  Asthma  Allergy Index. décimale : PER Périodiques Résumé : Maternal immune activity has been linked to children with autism spectrum disorder (ASD). We examined maternal occupational exposure to asthma-causing agents during pregnancy in relation to ASD risk. Our sample included 463 ASD cases and 710 general population controls from the Study to Explore Early Development whose mothers reported at least one job during pregnancy. Asthmagen exposure was estimated from a published job-exposure matrix. The adjusted odds ratio for ASD comparing asthmagen-exposed to unexposed was 1.39 (95 % CI 0.96–2.02). Maternal workplace asthmagen exposure was not associated with ASD risk in this study, but this result does not exclude some involvement of maternal exposure to asthma-causing agents in ASD. En ligne : http://dx.doi.org/10.1007/s10803-016-2882-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=293 [article] Maternal Exposure to Occupational Asthmagens During Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development [texte imprimé] / Alison B. SINGER, Auteur ; Gayle C. WINDHAM, Auteur ; Lisa A. CROEN, Auteur ; Julie L. DANIELS, Auteur ; Brian K. LEE, Auteur ; Yinge QIAN, Auteur ; Diana SCHENDEL, Auteur ; M. Daniele FALLIN, Auteur ; Igor BURSTYN, Auteur . - p.3458-3468. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-11 (November 2016) . - p.3458-3468 Mots-clés : Autism  Maternal occupation  Exposure  Maternal  Asthma  Allergy Index. décimale : PER Périodiques Résumé : Maternal immune activity has been linked to children with autism spectrum disorder (ASD). We examined maternal occupational exposure to asthma-causing agents during pregnancy in relation to ASD risk. Our sample included 463 ASD cases and 710 general population controls from the Study to Explore Early Development whose mothers reported at least one job during pregnancy. Asthmagen exposure was estimated from a published job-exposure matrix. The adjusted odds ratio for ASD comparing asthmagen-exposed to unexposed was 1.39 (95 % CI 0.96–2.02). Maternal workplace asthmagen exposure was not associated with ASD risk in this study, but this result does not exclude some involvement of maternal exposure to asthma-causing agents in ASD. En ligne : http://dx.doi.org/10.1007/s10803-016-2882-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=293

Response to letter from Ryan Collis / Amy LUTZ in Autism Research, 16-4 (April 2023)  

Public ISBD [article]  inAutism Research > 16-4 (April 2023) . - p.681-681 Titre : Response to letter from Ryan Collis Type de document : texte imprimé Auteurs : Amy LUTZ, Auteur ; Alison SINGER, Auteur ; Jill ESCHER, Auteur ; Alycia K. HALLADAY, Auteur Article en page(s) : p.681-681 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.2903 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499 [article] Response to letter from Ryan Collis [texte imprimé] / Amy LUTZ, Auteur ; Alison SINGER, Auteur ; Jill ESCHER, Auteur ; Alycia K. HALLADAY, Auteur . - p.681-681. Langues : Anglais (eng) in Autism Research > 16-4 (April 2023) . - p.681-681 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.2903 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499

Response to Natri / Alison SINGER in Autism Research, 16-4 (April 2023)  

Public ISBD [article]  inAutism Research > 16-4 (April 2023) . - p.677-677 Titre : Response to Natri Type de document : texte imprimé Auteurs : Alison SINGER, Auteur ; Jill ESCHER, Auteur ; Amy LUTZ, Auteur ; Alycia K. HALLADAY, Auteur Article en page(s) : p.677-677 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.2925 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499 [article] Response to Natri [texte imprimé] / Alison SINGER, Auteur ; Jill ESCHER, Auteur ; Amy LUTZ, Auteur ; Alycia K. HALLADAY, Auteur . - p.677-677. Langues : Anglais (eng) in Autism Research > 16-4 (April 2023) . - p.677-677 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.2925 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499

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