Aggressive behaviors and treatable risk factors of preschool children with autism spectrum disorder / Chen CHEN in Autism Research, 10-6 (June 2017)  

Public ISBD [article]  inAutism Research > 10-6 (June 2017) . - p.1155-1162 Titre : Aggressive behaviors and treatable risk factors of preschool children with autism spectrum disorder Type de document : texte imprimé Auteurs : Chen CHEN, Auteur ; Yi-Dong SHEN, Auteur ; Guang-Lei XUN, Auteur ; Wei-Xiong CAI, Auteur ; Li-Juan SHI, Auteur ; Lu XIAO, Auteur ; Ren-Rong WU, Auteur ; Jing-Ping ZHAO, Auteur ; Jian-Jun OU, Auteur Article en page(s) : p.1155-1162 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  aggressive behaviors  treatable risk factors  sleep problems  ADHD symptoms Index. décimale : PER Périodiques Résumé : Aggressive behaviors of children with autism spectrum disorder (ASD) are common. We conducted this study to describe the aggressive mode of preschool children with ASD and examine the associations between specific aggressive behaviors and two treatable factors: sleep problems and attention deficit hyperactivity disorder (ADHD) symptoms. In total, 577 typically developing (TD) children and 490 children with ASD were investigated in this study. The Institute for Basic Research – Modified Overt Aggression Scale (IBR-MOAS) was used to assess aggressive behaviors. Children's social impairments, sleep problems and ADHD symptoms were also measured with specific scales. The total IBR-MOAS score was significantly higher (worse) in the TD group [4.47 (5.36)] than in the ASD group [3.47 (5.63), P = 0.004]. The aggressive modes differed between groups: when compared with each other, the TD group received higher scores on Verbal and Physical Aggression Toward Others (all P < 0.01), while the ASD group had higher scores on Physical Aggression Against Self (P = 0.006). The linear regression model demonstrated that the aggressive behaviors of children with ASD were significantly associated with two treatable factors: sleep problems and ADHD symptoms. These findings have substantial clinical implications: treatment of these two risk factors may be helpful in managing aggressive behavior in children with ASD. En ligne : http://dx.doi.org/10.1002/aur.1751 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309 [article] Aggressive behaviors and treatable risk factors of preschool children with autism spectrum disorder [texte imprimé] / Chen CHEN, Auteur ; Yi-Dong SHEN, Auteur ; Guang-Lei XUN, Auteur ; Wei-Xiong CAI, Auteur ; Li-Juan SHI, Auteur ; Lu XIAO, Auteur ; Ren-Rong WU, Auteur ; Jing-Ping ZHAO, Auteur ; Jian-Jun OU, Auteur . - p.1155-1162. Langues : Anglais (eng) in Autism Research > 10-6 (June 2017) . - p.1155-1162 Mots-clés : autism spectrum disorder  aggressive behaviors  treatable risk factors  sleep problems  ADHD symptoms Index. décimale : PER Périodiques Résumé : Aggressive behaviors of children with autism spectrum disorder (ASD) are common. We conducted this study to describe the aggressive mode of preschool children with ASD and examine the associations between specific aggressive behaviors and two treatable factors: sleep problems and attention deficit hyperactivity disorder (ADHD) symptoms. In total, 577 typically developing (TD) children and 490 children with ASD were investigated in this study. The Institute for Basic Research – Modified Overt Aggression Scale (IBR-MOAS) was used to assess aggressive behaviors. Children's social impairments, sleep problems and ADHD symptoms were also measured with specific scales. The total IBR-MOAS score was significantly higher (worse) in the TD group [4.47 (5.36)] than in the ASD group [3.47 (5.63), P = 0.004]. The aggressive modes differed between groups: when compared with each other, the TD group received higher scores on Verbal and Physical Aggression Toward Others (all P < 0.01), while the ASD group had higher scores on Physical Aggression Against Self (P = 0.006). The linear regression model demonstrated that the aggressive behaviors of children with ASD were significantly associated with two treatable factors: sleep problems and ADHD symptoms. These findings have substantial clinical implications: treatment of these two risk factors may be helpful in managing aggressive behavior in children with ASD. En ligne : http://dx.doi.org/10.1002/aur.1751 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309

Changes in healthcare expenditures after the autism insurance mandate / Li WANG in Research in Autism Spectrum Disorders, 57 (January 2019)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 57 (January 2019) . - p.97-104 Titre : Changes in healthcare expenditures after the autism insurance mandate Type de document : texte imprimé Auteurs : Li WANG, Auteur ; Junyi MA, Auteur ; Ruchita DHOLAKIA, Auteur ; Callie HOWELLS, Auteur ; Yun LU, Auteur ; Chen CHEN, Auteur ; Runze LI, Auteur ; Michael J. MURRAY, Auteur ; Douglas L. LESLIE, Auteur Article en page(s) : p.97-104 Langues : Anglais (eng) Mots-clés : Autism mandate  Healthcare expenditures  Cost  Autism spectrum disorder  Private insurance Index. décimale : PER Périodiques Résumé : Background In recent years, most U.S. states have passed autism mandates requiring private insurers to cover autism spectrum disorders (ASD). Little is known about the post-mandate changes in healthcare expenditures. Method This study utilized 2006–2012 de-identified insurance claims data from the largest private insurer in Pennsylvania (PA), where the mandate went into effect in mid 2009. Healthcare expenditures were defined as the amount the insurer paid for healthcare services and were adjusted to 2012 price level. A mixed effects model was used to analyze the expenditures. Results A total of 9471 children with ASD were included. Although the pre-mandate total expenditures per child with ASD were similar, the post-mandate expenditures significantly increased for groups subject to the autism mandate (87% increase from $7754 in 2008 to $14,486 in 2010) compared to the exempt groups (27% increase from $7238 to $9171). By insurance type, the change from 2008 to 2010 in ASD-related expenditures per child with ASD was $8439 for fully insured large employer sponsored plans and $43 for the Children’s Health Insurance Program (CHIP), both subject to the PA mandate; and $2631 for the self-insured, $980 for small-employers, and $-92 for individual plans, all of which are exempt from the mandate. These increases were due to outpatient services but not inpatient or drug costs. Conclusions Healthcare expenditures increased significantly following the PA autism mandate. Nonexempt, large employer groups had the largest increase in spending. Some exempt, self-insured companies may have voluntarily covered ASD services, leading to a moderate increase. En ligne : https://doi.org/10.1016/j.rasd.2018.10.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371 [article] Changes in healthcare expenditures after the autism insurance mandate [texte imprimé] / Li WANG, Auteur ; Junyi MA, Auteur ; Ruchita DHOLAKIA, Auteur ; Callie HOWELLS, Auteur ; Yun LU, Auteur ; Chen CHEN, Auteur ; Runze LI, Auteur ; Michael J. MURRAY, Auteur ; Douglas L. LESLIE, Auteur . - p.97-104. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 57 (January 2019) . - p.97-104 Mots-clés : Autism mandate  Healthcare expenditures  Cost  Autism spectrum disorder  Private insurance Index. décimale : PER Périodiques Résumé : Background In recent years, most U.S. states have passed autism mandates requiring private insurers to cover autism spectrum disorders (ASD). Little is known about the post-mandate changes in healthcare expenditures. Method This study utilized 2006–2012 de-identified insurance claims data from the largest private insurer in Pennsylvania (PA), where the mandate went into effect in mid 2009. Healthcare expenditures were defined as the amount the insurer paid for healthcare services and were adjusted to 2012 price level. A mixed effects model was used to analyze the expenditures. Results A total of 9471 children with ASD were included. Although the pre-mandate total expenditures per child with ASD were similar, the post-mandate expenditures significantly increased for groups subject to the autism mandate (87% increase from $7754 in 2008 to $14,486 in 2010) compared to the exempt groups (27% increase from $7238 to $9171). By insurance type, the change from 2008 to 2010 in ASD-related expenditures per child with ASD was $8439 for fully insured large employer sponsored plans and $43 for the Children’s Health Insurance Program (CHIP), both subject to the PA mandate; and $2631 for the self-insured, $980 for small-employers, and $-92 for individual plans, all of which are exempt from the mandate. These increases were due to outpatient services but not inpatient or drug costs. Conclusions Healthcare expenditures increased significantly following the PA autism mandate. Nonexempt, large employer groups had the largest increase in spending. Some exempt, self-insured companies may have voluntarily covered ASD services, leading to a moderate increase. En ligne : https://doi.org/10.1016/j.rasd.2018.10.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371

Do parenting behaviors modify the way sensation seeking influences antisocial behaviors? / Mayumi OKUDA in Journal of Child Psychology and Psychiatry, 60-2 (February 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-2 (February 2019) . - p.169-177 Titre : Do parenting behaviors modify the way sensation seeking influences antisocial behaviors? Type de document : texte imprimé Auteurs : Mayumi OKUDA, Auteur ; Silvia S. MARTINS, Auteur ; Melanie WALL, Auteur ; Chen CHEN, Auteur ; Julian SANTAELLA-TENORIO, Auteur ; María A. RAMOS-OLAZAGASTI, Auteur ; Chiaying WEI, Auteur ; Glorisa CANINO, Auteur ; Héctor R. BIRD, Auteur ; Cristiane S. DUARTE, Auteur Année de publication : 2019 Article en page(s) : p.169-177 Langues : Anglais (eng) Mots-clés : Sensation seeking  antisocial behavior  child development  delinquency  parenting Index. décimale : PER Périodiques Résumé : BACKGROUND: Parenting behaviors have been shown to moderate the association between sensation seeking and antisocial behaviors. METHODS: Data were obtained from the Boricua Youth Study, a longitudinal study of 2,491 Puerto Rican youth living in the South Bronx, New York, and the metropolitan area of San Juan, Puerto Rico. First, we examined the prospective relationship between sensation seeking and antisocial behaviors across 3 yearly waves and whether this relationship varied by sociodemographic factors. Second, we examined the moderating role of parenting behaviors-including parental monitoring, warmth, and coercive discipline-on the prospective relationship between sensation seeking and antisocial behaviors. RESULTS: Sensation seeking was a strong predictor of antisocial behaviors for youth across two different sociocultural contexts. High parental monitoring buffered the association between sensation seeking and antisocial behaviors, protecting individuals with this trait. Low parental warmth was associated with high levels of antisocial behaviors, regardless of the sensation seeking level. Among those with high parental warmth, sensation seeking predicted antisocial behaviors, but the levels of antisocial behaviors were never as high as those of youth with low parental warmth. CONCLUSIONS: Study findings underscore the relevance of person-family context interactions in the development of antisocial behaviors. Future interventions should focus on the interplay between individual vulnerabilities and family context to prevent the unhealthy expression of a trait that is present in many individuals. En ligne : http://dx.doi.org/10.1111/jcpp.12954 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=381 [article] Do parenting behaviors modify the way sensation seeking influences antisocial behaviors? [texte imprimé] / Mayumi OKUDA, Auteur ; Silvia S. MARTINS, Auteur ; Melanie WALL, Auteur ; Chen CHEN, Auteur ; Julian SANTAELLA-TENORIO, Auteur ; María A. RAMOS-OLAZAGASTI, Auteur ; Chiaying WEI, Auteur ; Glorisa CANINO, Auteur ; Héctor R. BIRD, Auteur ; Cristiane S. DUARTE, Auteur . - 2019 . - p.169-177. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-2 (February 2019) . - p.169-177 Mots-clés : Sensation seeking  antisocial behavior  child development  delinquency  parenting Index. décimale : PER Périodiques Résumé : BACKGROUND: Parenting behaviors have been shown to moderate the association between sensation seeking and antisocial behaviors. METHODS: Data were obtained from the Boricua Youth Study, a longitudinal study of 2,491 Puerto Rican youth living in the South Bronx, New York, and the metropolitan area of San Juan, Puerto Rico. First, we examined the prospective relationship between sensation seeking and antisocial behaviors across 3 yearly waves and whether this relationship varied by sociodemographic factors. Second, we examined the moderating role of parenting behaviors-including parental monitoring, warmth, and coercive discipline-on the prospective relationship between sensation seeking and antisocial behaviors. RESULTS: Sensation seeking was a strong predictor of antisocial behaviors for youth across two different sociocultural contexts. High parental monitoring buffered the association between sensation seeking and antisocial behaviors, protecting individuals with this trait. Low parental warmth was associated with high levels of antisocial behaviors, regardless of the sensation seeking level. Among those with high parental warmth, sensation seeking predicted antisocial behaviors, but the levels of antisocial behaviors were never as high as those of youth with low parental warmth. CONCLUSIONS: Study findings underscore the relevance of person-family context interactions in the development of antisocial behaviors. Future interventions should focus on the interplay between individual vulnerabilities and family context to prevent the unhealthy expression of a trait that is present in many individuals. En ligne : http://dx.doi.org/10.1111/jcpp.12954 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=381

Improving the Diagnosis of Autism Spectrum Disorder in Fragile X Syndrome by Adapting the Social Communication Questionnaire and the Social Responsiveness Scale-2 / Sharon A. KIDD in Journal of Autism and Developmental Disorders, 50-9 (September 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-9 (September 2020) . - p.3276-3295 Titre : Improving the Diagnosis of Autism Spectrum Disorder in Fragile X Syndrome by Adapting the Social Communication Questionnaire and the Social Responsiveness Scale-2 Type de document : texte imprimé Auteurs : Sharon A. KIDD, Auteur ; Elizabeth BERRY-KRAVIS, Auteur ; Tse-Hwei CHOO, Auteur ; Chen CHEN, Auteur ; Amy N. ESLER, Auteur ; Anne HOFFMANN, Auteur ; Howard F. ANDREWS, Auteur ; Walter E. KAUFMANN, Auteur Article en page(s) : p.3276-3295 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Exploratory factor analysis  Fragile X syndrome  Receiver operating characteristic curves  Social Communication Questionnaire  Social Responsiveness Scale-2 Index. décimale : PER Périodiques Résumé : We carried out a psychometric assessment of the Social Communication Questionnaire (SCQ) and the Social Responsiveness Scale (SRS-2) in fragile X syndrome (FXS), relative to clinician DSM5-based diagnosis of autism spectrum disorder (ASD) in FXS. This was followed by instrument revisions that included: removal of non-discriminating and/or low face validity items for FXS; use of receiver operating characteristic (ROC) curves to determine optimal cut points for the original and revised measures; an exploratory factor analysis to outline subscales better representing ASD in FXS; and creation of a "triple criteria" diagnosis to better delineate ASD subgroups in FXS. These methods improved the sensitivity and/or specificity of the SCQ and SRS-2, but diagnostic accuracy of ASD remains problematic in FXS. En ligne : http://dx.doi.org/10.1007/s10803-019-04148-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430 [article] Improving the Diagnosis of Autism Spectrum Disorder in Fragile X Syndrome by Adapting the Social Communication Questionnaire and the Social Responsiveness Scale-2 [texte imprimé] / Sharon A. KIDD, Auteur ; Elizabeth BERRY-KRAVIS, Auteur ; Tse-Hwei CHOO, Auteur ; Chen CHEN, Auteur ; Amy N. ESLER, Auteur ; Anne HOFFMANN, Auteur ; Howard F. ANDREWS, Auteur ; Walter E. KAUFMANN, Auteur . - p.3276-3295. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-9 (September 2020) . - p.3276-3295 Mots-clés : Autism spectrum disorder  Exploratory factor analysis  Fragile X syndrome  Receiver operating characteristic curves  Social Communication Questionnaire  Social Responsiveness Scale-2 Index. décimale : PER Périodiques Résumé : We carried out a psychometric assessment of the Social Communication Questionnaire (SCQ) and the Social Responsiveness Scale (SRS-2) in fragile X syndrome (FXS), relative to clinician DSM5-based diagnosis of autism spectrum disorder (ASD) in FXS. This was followed by instrument revisions that included: removal of non-discriminating and/or low face validity items for FXS; use of receiver operating characteristic (ROC) curves to determine optimal cut points for the original and revised measures; an exploratory factor analysis to outline subscales better representing ASD in FXS; and creation of a "triple criteria" diagnosis to better delineate ASD subgroups in FXS. These methods improved the sensitivity and/or specificity of the SCQ and SRS-2, but diagnostic accuracy of ASD remains problematic in FXS. En ligne : http://dx.doi.org/10.1007/s10803-019-04148-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430

Pharmacologic Interventions for Irritability, Aggression, Agitation and Self-Injurious Behavior in Fragile X Syndrome: An Initial Cross-Sectional Analysis / Eleanor M. ECKERT in Journal of Autism and Developmental Disorders, 49-11 (November 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-11 (November 2019) . - p.4595-4602 Titre : Pharmacologic Interventions for Irritability, Aggression, Agitation and Self-Injurious Behavior in Fragile X Syndrome: An Initial Cross-Sectional Analysis Type de document : texte imprimé Auteurs : Eleanor M. ECKERT, Auteur ; Kelli C. DOMINICK, Auteur ; Ernest V. PEDAPATI, Auteur ; Logan K. WINK, Auteur ; Rebecca C. SHAFFER, Auteur ; Howard ANDREWS, Auteur ; Tse-Hwei CHOO, Auteur ; Chen CHEN, Auteur ; Walter E. KAUFMANN, Auteur ; Nicole TARTAGLIA, Auteur ; Elizabeth BERRY-KRAVIS, Auteur ; Craig ERICKSON, Auteur Année de publication : 2019 Article en page(s) : p.4595-4602 Langues : Anglais (eng) Mots-clés : Fragile X syndrome  Irritability  Pharmacotherapy Index. décimale : PER Périodiques Résumé : Using a dataset involving 415 individuals with irritability, aggression, agitation and self-injury (IAAS) behaviors from the fragile X syndrome (FXS) FORWARD database, we describe the psychopharmacologic management of IAAS and features of the population of persons with FXS treated with drug therapy for IAAS. Among those with FXS exhibiting IAAS, individuals with FXS receiving drug treatment of IAAS were older, more predominantly male, have more significant intellectual disability, more like to have comorbid autism, hyperarousal, and social impairments. The most commonly utilized medications for IAAS in FXS are antipsychotic medications, specifically aripiprazole and risperidone (37% and 27%, respectively). The majority of subjects (63%) experienced no side effects noted from the use of their psychopharmacologic medications. En ligne : http://dx.doi.org/10.1007/s10803-019-04173-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=408 [article] Pharmacologic Interventions for Irritability, Aggression, Agitation and Self-Injurious Behavior in Fragile X Syndrome: An Initial Cross-Sectional Analysis [texte imprimé] / Eleanor M. ECKERT, Auteur ; Kelli C. DOMINICK, Auteur ; Ernest V. PEDAPATI, Auteur ; Logan K. WINK, Auteur ; Rebecca C. SHAFFER, Auteur ; Howard ANDREWS, Auteur ; Tse-Hwei CHOO, Auteur ; Chen CHEN, Auteur ; Walter E. KAUFMANN, Auteur ; Nicole TARTAGLIA, Auteur ; Elizabeth BERRY-KRAVIS, Auteur ; Craig ERICKSON, Auteur . - 2019 . - p.4595-4602. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-11 (November 2019) . - p.4595-4602 Mots-clés : Fragile X syndrome  Irritability  Pharmacotherapy Index. décimale : PER Périodiques Résumé : Using a dataset involving 415 individuals with irritability, aggression, agitation and self-injury (IAAS) behaviors from the fragile X syndrome (FXS) FORWARD database, we describe the psychopharmacologic management of IAAS and features of the population of persons with FXS treated with drug therapy for IAAS. Among those with FXS exhibiting IAAS, individuals with FXS receiving drug treatment of IAAS were older, more predominantly male, have more significant intellectual disability, more like to have comorbid autism, hyperarousal, and social impairments. The most commonly utilized medications for IAAS in FXS are antipsychotic medications, specifically aripiprazole and risperidone (37% and 27%, respectively). The majority of subjects (63%) experienced no side effects noted from the use of their psychopharmacologic medications. En ligne : http://dx.doi.org/10.1007/s10803-019-04173-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=408

Sex differences in global and local connectivity of adolescent posttraumatic stress disorder symptoms / Xing CAO in Journal of Child Psychology and Psychiatry, 60-2 (February 2019)  

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