Exposure to General Anesthesia May Contribute to the Association between Cesarean Delivery and Autism Spectrum Disorder / M. HUBERMAN SAMUEL in Journal of Autism and Developmental Disorders, 49-8 (August 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-8 (August 2019) . - p.3127-3135 Titre : Exposure to General Anesthesia May Contribute to the Association between Cesarean Delivery and Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : M. HUBERMAN SAMUEL, Auteur ; G. MEIRI, Auteur ; I. DINSTEIN, Auteur ; H. FLUSSER, Auteur ; A. MICHAELOVSKI, Auteur ; Asher BASHIRI, Auteur ; I. MENASHE, Auteur Article en page(s) : p.3127-3135 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Cesarean section  General anesthesia Index. décimale : PER Périodiques Résumé : Cesarean section (CS) has been consistently associated with susceptibility to autism spectrum disorder (ASD), however, the underlying mechanism for this association remains vague. Here, we studied various pre-peri-and-neonatal factors among 347 children with ASD, 117 children with other developmental delays (DD), and 2226 age, sex and ethnicity matched controls. We found that CS is significantly associated with an increased risk of ASD but not DD (p = 0.019 and p = 0.540 respectively). Furthermore, we show that only CS performed with general anesthesia (GA) elevated the risk of ASD with no significant difference between indicated and non-indicated surgeries (aOR = 1.537; 95% CI 1.026-2.302, and aOR = 1.692; 95% CI 1.057-2.709, pdiff = 0.865). We therefore suggest that exposure to GA during CS may explain the association between CS and ASD. En ligne : http://dx.doi.org/10.1007/s10803-019-04034-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403 [article] Exposure to General Anesthesia May Contribute to the Association between Cesarean Delivery and Autism Spectrum Disorder [Texte imprimé et/ou numérique] / M. HUBERMAN SAMUEL, Auteur ; G. MEIRI, Auteur ; I. DINSTEIN, Auteur ; H. FLUSSER, Auteur ; A. MICHAELOVSKI, Auteur ; Asher BASHIRI, Auteur ; I. MENASHE, Auteur . - p.3127-3135. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-8 (August 2019) . - p.3127-3135 Mots-clés : Autism spectrum disorder  Cesarean section  General anesthesia Index. décimale : PER Périodiques Résumé : Cesarean section (CS) has been consistently associated with susceptibility to autism spectrum disorder (ASD), however, the underlying mechanism for this association remains vague. Here, we studied various pre-peri-and-neonatal factors among 347 children with ASD, 117 children with other developmental delays (DD), and 2226 age, sex and ethnicity matched controls. We found that CS is significantly associated with an increased risk of ASD but not DD (p = 0.019 and p = 0.540 respectively). Furthermore, we show that only CS performed with general anesthesia (GA) elevated the risk of ASD with no significant difference between indicated and non-indicated surgeries (aOR = 1.537; 95% CI 1.026-2.302, and aOR = 1.692; 95% CI 1.057-2.709, pdiff = 0.865). We therefore suggest that exposure to GA during CS may explain the association between CS and ASD. En ligne : http://dx.doi.org/10.1007/s10803-019-04034-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403

Sleep Disturbances and Sensory Sensitivities Co-Vary in a Longitudinal Manner in Pre-School Children with Autism Spectrum Disorders / L. MANELIS-BARAM in Journal of Autism and Developmental Disorders, 52-2 (February 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-2 (February 2022) . - p.923-937 Titre : Sleep Disturbances and Sensory Sensitivities Co-Vary in a Longitudinal Manner in Pre-School Children with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : L. MANELIS-BARAM, Auteur ; G. MEIRI, Auteur ; M. ILAN, Auteur ; M. FAROY, Auteur ; A. MICHAELOVSKI, Auteur ; H. FLUSSER, Auteur ; I. MENASHE, Auteur ; I. DINSTEIN, Auteur Article en page(s) : p.923-937 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis  Child  Child, Preschool  Cross-Sectional Studies  Humans  Sensation  Sleep  Sleep Wake Disorders/diagnosis/epidemiology  Autism Spectrum disorder  Sensory processing  Sensory sensitivities  Sleep disturbances Index. décimale : PER Périodiques Résumé : Previous research has demonstrated that sleep disturbances are positively correlated with sensory sensitivities in children with ASD. Most of these studies, however, were based on cross-sectional analyses, where the relationship across symptom domains was examined at a single time-point. Here, we examined the development of 103 pre-school children with ASD over a 1-3-year period. The results revealed that spontaneous longitudinal changes in sleep disturbances were specifically correlated with changes in sensory sensitivities and not with changes in other sensory processing domains nor with changes in core ASD symptoms. These finding demonstrate a consistent longitudinal relationship between sleep disturbances and sensory sensitivities, which suggests that these symptoms may be generated by common or interacting underlying physiological mechanisms. En ligne : http://dx.doi.org/10.1007/s10803-021-04973-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 [article] Sleep Disturbances and Sensory Sensitivities Co-Vary in a Longitudinal Manner in Pre-School Children with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / L. MANELIS-BARAM, Auteur ; G. MEIRI, Auteur ; M. ILAN, Auteur ; M. FAROY, Auteur ; A. MICHAELOVSKI, Auteur ; H. FLUSSER, Auteur ; I. MENASHE, Auteur ; I. DINSTEIN, Auteur . - p.923-937. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-2 (February 2022) . - p.923-937 Mots-clés : Autism Spectrum Disorder/diagnosis  Child  Child, Preschool  Cross-Sectional Studies  Humans  Sensation  Sleep  Sleep Wake Disorders/diagnosis/epidemiology  Autism Spectrum disorder  Sensory processing  Sensory sensitivities  Sleep disturbances Index. décimale : PER Périodiques Résumé : Previous research has demonstrated that sleep disturbances are positively correlated with sensory sensitivities in children with ASD. Most of these studies, however, were based on cross-sectional analyses, where the relationship across symptom domains was examined at a single time-point. Here, we examined the development of 103 pre-school children with ASD over a 1-3-year period. The results revealed that spontaneous longitudinal changes in sleep disturbances were specifically correlated with changes in sensory sensitivities and not with changes in other sensory processing domains nor with changes in core ASD symptoms. These finding demonstrate a consistent longitudinal relationship between sleep disturbances and sensory sensitivities, which suggests that these symptoms may be generated by common or interacting underlying physiological mechanisms. En ligne : http://dx.doi.org/10.1007/s10803-021-04973-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455

Sleep disturbances are associated with specific sensory sensitivities in children with autism / O. TZISCHINSKY in Molecular Autism, 9 (2018)  

Public ISBD [article]  inMolecular Autism > 9 (2018) . - 22p. Titre : Sleep disturbances are associated with specific sensory sensitivities in children with autism Type de document : Texte imprimé et/ou numérique Auteurs : O. TZISCHINSKY, Auteur ; G. MEIRI, Auteur ; L. MANELIS, Auteur ; A. BAR-SINAI, Auteur ; H. FLUSSER, Auteur ; A. MICHAELOVSKI, Auteur ; O. ZIVAN, Auteur ; M. ILAN, Auteur ; M. FAROY, Auteur ; I. MENASHE, Auteur ; I. DINSTEIN, Auteur Article en page(s) : 22p. Langues : Anglais (eng) Mots-clés : Autism  Children  Hypersensitivity towards touch  Sensory abnormalities  Sleep disturbances Index. décimale : PER Périodiques Résumé : Background: Sensory abnormalities and sleep disturbances are highly prevalent in children with autism, but the potential relationship between these two domains has rarely been explored. Understanding such relationships is important for identifying children with autism who exhibit more homogeneous symptoms. Methods: Here, we examined this relationship using the Caregiver Sensory Profile and the Children's Sleep Habits Questionnaire, which were completed by parents of 69 children with autism and 62 age-matched controls. Results: In line with previous studies, children with autism exhibited more severe sensory abnormalities and sleep disturbances than age-matched controls. The sleep disturbance scores were moderately associated with touch and oral sensitivities in the autism group and with touch and vestibular sensitivities in the control group. Hypersensitivity towards touch, in particular, exhibited the strongest relationship with sleep disturbances in the autism group and single-handedly explained 24% of the variance in total sleep disturbance scores. In contrast, sensitivity in other sensory domains such as vision and audition was not associated with sleep quality in either group. Conclusions: While it is often assumed that sensitivities in all sensory domains are similarly associated with sleep problems, our results suggest that hypersensitivity towards touch exhibits the strongest relationship with sleep disturbances when examining children autism. We speculate that hypersensitivity towards touch interferes with sleep onset and maintenance in a considerable number of children with autism who exhibit severe sleep disturbances. This may indicate the existence of a specific sleep disturbance mechanism that is associated with sensitivity to touch, which may be important to consider in future scientific and clinical studies. En ligne : http://dx.doi.org/10.1186/s13229-018-0206-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=354 [article] Sleep disturbances are associated with specific sensory sensitivities in children with autism [Texte imprimé et/ou numérique] / O. TZISCHINSKY, Auteur ; G. MEIRI, Auteur ; L. MANELIS, Auteur ; A. BAR-SINAI, Auteur ; H. FLUSSER, Auteur ; A. MICHAELOVSKI, Auteur ; O. ZIVAN, Auteur ; M. ILAN, Auteur ; M. FAROY, Auteur ; I. MENASHE, Auteur ; I. DINSTEIN, Auteur . - 22p. Langues : Anglais (eng) in Molecular Autism > 9 (2018) . - 22p. Mots-clés : Autism  Children  Hypersensitivity towards touch  Sensory abnormalities  Sleep disturbances Index. décimale : PER Périodiques Résumé : Background: Sensory abnormalities and sleep disturbances are highly prevalent in children with autism, but the potential relationship between these two domains has rarely been explored. Understanding such relationships is important for identifying children with autism who exhibit more homogeneous symptoms. Methods: Here, we examined this relationship using the Caregiver Sensory Profile and the Children's Sleep Habits Questionnaire, which were completed by parents of 69 children with autism and 62 age-matched controls. Results: In line with previous studies, children with autism exhibited more severe sensory abnormalities and sleep disturbances than age-matched controls. The sleep disturbance scores were moderately associated with touch and oral sensitivities in the autism group and with touch and vestibular sensitivities in the control group. Hypersensitivity towards touch, in particular, exhibited the strongest relationship with sleep disturbances in the autism group and single-handedly explained 24% of the variance in total sleep disturbance scores. In contrast, sensitivity in other sensory domains such as vision and audition was not associated with sleep quality in either group. Conclusions: While it is often assumed that sensitivities in all sensory domains are similarly associated with sleep problems, our results suggest that hypersensitivity towards touch exhibits the strongest relationship with sleep disturbances when examining children autism. We speculate that hypersensitivity towards touch interferes with sleep onset and maintenance in a considerable number of children with autism who exhibit severe sleep disturbances. This may indicate the existence of a specific sleep disturbance mechanism that is associated with sensitivity to touch, which may be important to consider in future scientific and clinical studies. En ligne : http://dx.doi.org/10.1186/s13229-018-0206-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=354

---

1 (1 - 3 / 3)