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Auteur Deborah CHRISTENSEN |
Documents disponibles écrits par cet auteur (3)



Behavioral problems in children with autism spectrum disorder with and without co-occurring intellectual disability / Margaret KURZIUS-SPENCER in Research in Autism Spectrum Disorders, 56 (December 2018)
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[article]
Titre : Behavioral problems in children with autism spectrum disorder with and without co-occurring intellectual disability Type de document : Texte imprimé et/ou numérique Auteurs : Margaret KURZIUS-SPENCER, Auteur ; Sydney PETTYGROVE, Auteur ; Deborah CHRISTENSEN, Auteur ; Anita L. PEDERSEN, Auteur ; Christopher CUNNIFF, Auteur ; F. John MEANEY, Auteur ; Gnakub Norbert SOKE, Auteur ; Rebecca A. HARRINGTON, Auteur ; Maureen DURKIN, Auteur ; Sydney RICE, Auteur Article en page(s) : p.61-71 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Intellectual disability Self-injurious behavior Problem behaviors Autism and developmental disabilities monitoring network Children Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD), intellectual disability (ID), and behavioral problems commonly co-occur, leading to increased impairment, diagnostic confusion, and treatment delays. Using data from a large surveillance population of children with ASD, the objectives of the present study were to compare the relative risk of common behavioral problems in children with ASD, with and without co-occurring intellectual disability. Methods Data from the Autism and Developmental Disabilities Monitoring (ADDM) Network (2006–2010) on 9378 8-year-old children who met case definition for ASD and had cognitive test scores and information on behavioral problems were analyzed using frequency measures, risk ratios, chi-squared tests, and trend tests. Results Children with ASD with and without ID had on average six co-occurring behavioral problems. The relative risk (RR) of self-injurious behaviors, unusual fear responses, and eating abnormalities increased with increasing cognitive impairment among children with ASD and ID (all p<0.001). Conversely, RR of mood (p<0.001) and sleep abnormalities (p=0.013) declined with increasing levels of cognitive impairment. Conclusions Children with ASD and ID are at greater risk of some behavioral problems and lower risk of others as compared to children with ASD only. Successful interventions depend on understanding the complex interactions between co-occurring neurodevelopmental and behavioral problems. En ligne : https://doi.org/10.1016/j.rasd.2018.09.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369
in Research in Autism Spectrum Disorders > 56 (December 2018) . - p.61-71[article] Behavioral problems in children with autism spectrum disorder with and without co-occurring intellectual disability [Texte imprimé et/ou numérique] / Margaret KURZIUS-SPENCER, Auteur ; Sydney PETTYGROVE, Auteur ; Deborah CHRISTENSEN, Auteur ; Anita L. PEDERSEN, Auteur ; Christopher CUNNIFF, Auteur ; F. John MEANEY, Auteur ; Gnakub Norbert SOKE, Auteur ; Rebecca A. HARRINGTON, Auteur ; Maureen DURKIN, Auteur ; Sydney RICE, Auteur . - p.61-71.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 56 (December 2018) . - p.61-71
Mots-clés : Autism spectrum disorder Intellectual disability Self-injurious behavior Problem behaviors Autism and developmental disabilities monitoring network Children Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD), intellectual disability (ID), and behavioral problems commonly co-occur, leading to increased impairment, diagnostic confusion, and treatment delays. Using data from a large surveillance population of children with ASD, the objectives of the present study were to compare the relative risk of common behavioral problems in children with ASD, with and without co-occurring intellectual disability. Methods Data from the Autism and Developmental Disabilities Monitoring (ADDM) Network (2006–2010) on 9378 8-year-old children who met case definition for ASD and had cognitive test scores and information on behavioral problems were analyzed using frequency measures, risk ratios, chi-squared tests, and trend tests. Results Children with ASD with and without ID had on average six co-occurring behavioral problems. The relative risk (RR) of self-injurious behaviors, unusual fear responses, and eating abnormalities increased with increasing cognitive impairment among children with ASD and ID (all p<0.001). Conversely, RR of mood (p<0.001) and sleep abnormalities (p=0.013) declined with increasing levels of cognitive impairment. Conclusions Children with ASD and ID are at greater risk of some behavioral problems and lower risk of others as compared to children with ASD only. Successful interventions depend on understanding the complex interactions between co-occurring neurodevelopmental and behavioral problems. En ligne : https://doi.org/10.1016/j.rasd.2018.09.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369 Disparities in Documented Diagnoses of Autism Spectrum Disorder Based on Demographic, Individual, and Service Factors / Lisa D. WIGGINS in Autism Research, 13-3 (March 2020)
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Titre : Disparities in Documented Diagnoses of Autism Spectrum Disorder Based on Demographic, Individual, and Service Factors Type de document : Texte imprimé et/ou numérique Auteurs : Lisa D. WIGGINS, Auteur ; Maureen DURKIN, Auteur ; Amy ESLER, Auteur ; Li-Ching LEE, Auteur ; Walter ZAHORODNY, Auteur ; Catherine RICE, Auteur ; Marshalyn YEARGIN-ALLSOPP, Auteur ; Nicole F. DOWLING, Auteur ; Jennifer HALL-LANDE, Auteur ; Michael J. MORRIER, Auteur ; Deborah CHRISTENSEN, Auteur ; Josephine SHENOUDA, Auteur ; Jon BAIO, Auteur Article en page(s) : p.464-473 Langues : Anglais (eng) Mots-clés : autism diagnosis disparities surveillance Index. décimale : PER Périodiques Résumé : The objectives of our study were to (a) report how many children met an autism spectrum disorder (ASD) surveillance definition but had no clinical diagnosis of ASD in health or education records and (b) evaluate differences in demographic, individual, and service factors between children with and without a documented ASD diagnosis. ASD surveillance was conducted in selected areas of Arizona, Arkansas, Colorado, Georgia, Maryland, Minnesota, Missouri, New Jersey, North Carolina, Tennessee, and Wisconsin. Children were defined as having ASD if sufficient social and behavioral deficits and/or an ASD diagnosis were noted in health and/or education records. Among 4,498 children, 1,135 (25%) had ASD indicators without having an ASD diagnosis. Of those 1,135 children without a documented ASD diagnosis, 628 (55%) were not known to receive ASD services in public school. Factors associated with not having a clinical diagnosis of ASD were non-White race, no intellectual disability, older age at first developmental concern, older age at first developmental evaluation, special education eligibility other than ASD, and need for fewer supports. These results highlight the importance of reducing disparities in the diagnosis of children with ASD characteristics so that appropriate interventions can be promoted across communities. Autism Res 2020, 13: 464-473. (c) 2019 International Society for AutismResearch,Wiley Periodicals, Inc. LAY SUMMARY: Children who did not have a clinical diagnosis of autism spectrum disorder (ASD) documented in health or education records were more likely to be non-White and have fewer developmental problems than children with a clinical diagnosis of ASD. They were brought to the attention of healthcare providers at older ages and needed fewer supports than children with a clinical diagnosis of ASD. All children with ASD symptoms who meet diagnostic criteria should be given a clinical diagnosis so they can receive treatment specific to their needs. En ligne : http://dx.doi.org/10.1002/aur.2255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421
in Autism Research > 13-3 (March 2020) . - p.464-473[article] Disparities in Documented Diagnoses of Autism Spectrum Disorder Based on Demographic, Individual, and Service Factors [Texte imprimé et/ou numérique] / Lisa D. WIGGINS, Auteur ; Maureen DURKIN, Auteur ; Amy ESLER, Auteur ; Li-Ching LEE, Auteur ; Walter ZAHORODNY, Auteur ; Catherine RICE, Auteur ; Marshalyn YEARGIN-ALLSOPP, Auteur ; Nicole F. DOWLING, Auteur ; Jennifer HALL-LANDE, Auteur ; Michael J. MORRIER, Auteur ; Deborah CHRISTENSEN, Auteur ; Josephine SHENOUDA, Auteur ; Jon BAIO, Auteur . - p.464-473.
Langues : Anglais (eng)
in Autism Research > 13-3 (March 2020) . - p.464-473
Mots-clés : autism diagnosis disparities surveillance Index. décimale : PER Périodiques Résumé : The objectives of our study were to (a) report how many children met an autism spectrum disorder (ASD) surveillance definition but had no clinical diagnosis of ASD in health or education records and (b) evaluate differences in demographic, individual, and service factors between children with and without a documented ASD diagnosis. ASD surveillance was conducted in selected areas of Arizona, Arkansas, Colorado, Georgia, Maryland, Minnesota, Missouri, New Jersey, North Carolina, Tennessee, and Wisconsin. Children were defined as having ASD if sufficient social and behavioral deficits and/or an ASD diagnosis were noted in health and/or education records. Among 4,498 children, 1,135 (25%) had ASD indicators without having an ASD diagnosis. Of those 1,135 children without a documented ASD diagnosis, 628 (55%) were not known to receive ASD services in public school. Factors associated with not having a clinical diagnosis of ASD were non-White race, no intellectual disability, older age at first developmental concern, older age at first developmental evaluation, special education eligibility other than ASD, and need for fewer supports. These results highlight the importance of reducing disparities in the diagnosis of children with ASD characteristics so that appropriate interventions can be promoted across communities. Autism Res 2020, 13: 464-473. (c) 2019 International Society for AutismResearch,Wiley Periodicals, Inc. LAY SUMMARY: Children who did not have a clinical diagnosis of autism spectrum disorder (ASD) documented in health or education records were more likely to be non-White and have fewer developmental problems than children with a clinical diagnosis of ASD. They were brought to the attention of healthcare providers at older ages and needed fewer supports than children with a clinical diagnosis of ASD. All children with ASD symptoms who meet diagnostic criteria should be given a clinical diagnosis so they can receive treatment specific to their needs. En ligne : http://dx.doi.org/10.1002/aur.2255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421 Features that best define the heterogeneity and homogeneity of autism in preschool-age children: A multisite case?control analysis replicated across two independent samples / Lisa D. WIGGINS in Autism Research, 15-3 (March 2022)
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[article]
Titre : Features that best define the heterogeneity and homogeneity of autism in preschool-age children: A multisite case?control analysis replicated across two independent samples Type de document : Texte imprimé et/ou numérique Auteurs : Lisa D. WIGGINS, Auteur ; Lin H. TIAN, Auteur ; Eric RUBENSTEIN, Auteur ; Laura A. SCHIEVE, Auteur ; Julie L. DANIELS, Auteur ; Karen PAZOL, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; Brian BARGER, Auteur ; Eric MOODY, Auteur ; Steven ROSENBERG, Auteur ; Chyrise BRADLEY, Auteur ; Melanie HSU, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur ; Deborah CHRISTENSEN, Auteur ; Tessa CRUME, Auteur ; Juhi PANDEY, Auteur ; Susan E. LEVY, Auteur Article en page(s) : p.539-550 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract The heterogeneous nature of children with symptoms of autism spectrum disorder (ASD) makes it difficult to identify risk factors and effective treatment options. We sought to identify behavioral and developmental features that best define the heterogeneity and homogeneity in 2?5-year-old children classified with ASD and subthreshold ASD characteristics. Children were enrolled in a multisite case?control study of ASD. Detailed behavioral and developmental data were gathered by maternal telephone interview, parent-administered questionnaires, child cognitive evaluation, and ASD diagnostic measures. Participants with a positive ASD screen score or prior ASD diagnosis were referred for comprehensive evaluation. Children in the ASD group met study criteria based on this evaluation; children who did not meet study criteria were categorized as having subthreshold ASD characteristics. There were 1480 children classified as ASD (81.6% boys) and 594 children classified as having subthreshold ASD characteristics (70.2% boys) in the sample. Factors associated with dysregulation (e.g., aggression, anxiety/depression, sleep problems) followed by developmental abilities (e.g., expressive and receptive language skills) most contributed to heterogeneity in both groups of children. Atypical sensory response contributed to homogeneity in children classified as ASD but not those with subthreshold characteristics. These findings suggest that dysregulation and developmental abilities are clinical features that can impact functioning in children with ASD and other DD, and that documenting these features in pediatric records may help meet the needs of the individual child. Sensory dysfunction could be considered a core feature of ASD and thus used to inform more targeted screening, evaluation, treatment, and research efforts. Lay summary The diverse nature of autism spectrum disorder (ASD) makes it difficult to find risk factors and treatment options. We identified the most dissimilar and most similar symptom(s) in children classified as ASD and as having subthreshold ASD characteristics. Factors associated with dysregulation and developmental abilities contributed to diversity in both groups of children. Sensory dysfunction was the most common symptom in children with ASD but not those with subthreshold characteristics. Findings can inform clinical practice and research. En ligne : https://doi.org/10.1002/aur.2663 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=473
in Autism Research > 15-3 (March 2022) . - p.539-550[article] Features that best define the heterogeneity and homogeneity of autism in preschool-age children: A multisite case?control analysis replicated across two independent samples [Texte imprimé et/ou numérique] / Lisa D. WIGGINS, Auteur ; Lin H. TIAN, Auteur ; Eric RUBENSTEIN, Auteur ; Laura A. SCHIEVE, Auteur ; Julie L. DANIELS, Auteur ; Karen PAZOL, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; Brian BARGER, Auteur ; Eric MOODY, Auteur ; Steven ROSENBERG, Auteur ; Chyrise BRADLEY, Auteur ; Melanie HSU, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur ; Deborah CHRISTENSEN, Auteur ; Tessa CRUME, Auteur ; Juhi PANDEY, Auteur ; Susan E. LEVY, Auteur . - p.539-550.
Langues : Anglais (eng)
in Autism Research > 15-3 (March 2022) . - p.539-550
Index. décimale : PER Périodiques Résumé : Abstract The heterogeneous nature of children with symptoms of autism spectrum disorder (ASD) makes it difficult to identify risk factors and effective treatment options. We sought to identify behavioral and developmental features that best define the heterogeneity and homogeneity in 2?5-year-old children classified with ASD and subthreshold ASD characteristics. Children were enrolled in a multisite case?control study of ASD. Detailed behavioral and developmental data were gathered by maternal telephone interview, parent-administered questionnaires, child cognitive evaluation, and ASD diagnostic measures. Participants with a positive ASD screen score or prior ASD diagnosis were referred for comprehensive evaluation. Children in the ASD group met study criteria based on this evaluation; children who did not meet study criteria were categorized as having subthreshold ASD characteristics. There were 1480 children classified as ASD (81.6% boys) and 594 children classified as having subthreshold ASD characteristics (70.2% boys) in the sample. Factors associated with dysregulation (e.g., aggression, anxiety/depression, sleep problems) followed by developmental abilities (e.g., expressive and receptive language skills) most contributed to heterogeneity in both groups of children. Atypical sensory response contributed to homogeneity in children classified as ASD but not those with subthreshold characteristics. These findings suggest that dysregulation and developmental abilities are clinical features that can impact functioning in children with ASD and other DD, and that documenting these features in pediatric records may help meet the needs of the individual child. Sensory dysfunction could be considered a core feature of ASD and thus used to inform more targeted screening, evaluation, treatment, and research efforts. Lay summary The diverse nature of autism spectrum disorder (ASD) makes it difficult to find risk factors and treatment options. We identified the most dissimilar and most similar symptom(s) in children classified as ASD and as having subthreshold ASD characteristics. Factors associated with dysregulation and developmental abilities contributed to diversity in both groups of children. Sensory dysfunction was the most common symptom in children with ASD but not those with subthreshold characteristics. Findings can inform clinical practice and research. En ligne : https://doi.org/10.1002/aur.2663 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=473