Brief Report: Face Configuration Accuracy and Processing Speed Among Adults with High-Functioning Autism Spectrum Disorders / Susan FAJA in Journal of Autism and Developmental Disorders, 39-3 (March 2009)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 39-3 (March 2009) . - p.532-538 Titre : Brief Report: Face Configuration Accuracy and Processing Speed Among Adults with High-Functioning Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Susan FAJA, Auteur ; Geraldine DAWSON, Auteur ; Elizabeth H. AYLWARD, Auteur ; Sara Jane WEBB, Auteur ; Kristen MERKLE, Auteur Année de publication : 2009 Article en page(s) : p.532-538 Langues : Anglais (eng) Mots-clés : Social-cognition Configural-processing Holistic-processing High-functioning-autism Asperger’s-disorder Index. décimale : PER Périodiques Résumé : The present study investigates the accuracy and speed of face processing employed by high-functioning adults with autism spectrum disorders (ASDs). Two behavioral experiments measured sensitivity to distances between features and face recognition when performance depended on holistic versus featural information. Results suggest adults with ASD were less accurate, but responded as quickly as controls for both tasks. In contrast to previous findings with children, adults with ASD demonstrated a holistic advantage only when the eye region was tested. Both groups recognized large manipulations to second-order relations more accurately than no change or small changes, but controls responded more quickly than participants with ASD when recognizing these large manipulations to configural information. En ligne : http://dx.doi.org/10.1007/s10803-008-0635-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=697 [article] Brief Report: Face Configuration Accuracy and Processing Speed Among Adults with High-Functioning Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Susan FAJA, Auteur ; Geraldine DAWSON, Auteur ; Elizabeth H. AYLWARD, Auteur ; Sara Jane WEBB, Auteur ; Kristen MERKLE, Auteur . - 2009 . - p.532-538. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 39-3 (March 2009) . - p.532-538 Mots-clés : Social-cognition Configural-processing Holistic-processing High-functioning-autism Asperger’s-disorder Index. décimale : PER Périodiques Résumé : The present study investigates the accuracy and speed of face processing employed by high-functioning adults with autism spectrum disorders (ASDs). Two behavioral experiments measured sensitivity to distances between features and face recognition when performance depended on holistic versus featural information. Results suggest adults with ASD were less accurate, but responded as quickly as controls for both tasks. In contrast to previous findings with children, adults with ASD demonstrated a holistic advantage only when the eye region was tested. Both groups recognized large manipulations to second-order relations more accurately than no change or small changes, but controls responded more quickly than participants with ASD when recognizing these large manipulations to configural information. En ligne : http://dx.doi.org/10.1007/s10803-008-0635-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=697

Early predictors of language skills at 3?years of age vary based on diagnostic outcome: A baby siblings research consortium study / Meredith PECUKONIS in Autism Research, 15-7 (July 2022)  

Public ISBD [article]  inAutism Research > 15-7 (July 2022) . - p.1324-1335 Titre : Early predictors of language skills at 3?years of age vary based on diagnostic outcome: A baby siblings research consortium study Type de document : Texte imprimé et/ou numérique Auteurs : Meredith PECUKONIS, Auteur ; Gregory S. YOUNG, Auteur ; Jessica BRIAN, Auteur ; Tony CHARMAN, Auteur ; Katarzyna CHAWARSKA, Auteur ; Mayada ELSABBAGH, Auteur ; Jana M. IVERSON, Auteur ; Shafali JESTE, Auteur ; Rebecca LANDA, Auteur ; Daniel S. MESSINGER, Auteur ; A. J. SCHWICHTENBERG, Auteur ; Sara Jane WEBB, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Helen TAGER-FLUSBERG, Auteur Article en page(s) : p.1324-1335 Langues : Anglais (eng) Mots-clés : gesture  infant sibling  language  maternal education  motor  nonverbal cognition Index. décimale : PER Périodiques Résumé : While previous work has identified the early predictors of language skills in infants at elevated familial risk (ER) and low familial risk (LR) for autism spectrum disorder (ASD), no studies to date have explored whether these predictors vary based on diagnostic outcome of ASD or no ASD. The present study used a large, multisite dataset to examine associations between a set of commonly studied predictor variables (infant gesture abilities, fine motor skills, nonverbal cognition, and maternal education level), measured at 12?months, and language skills, measured at 3?years, across three diagnostic outcome groups-infants with ASD ("ASD"), ER infants without ASD ("ER-no ASD"), and LR infants without ASD ("LR-no ASD"). Findings revealed that the predictors of language skills differed across groups, as gesture abilities were positively associated with language skills in the ER-no ASD group but negatively associated with language skills in the ASD group. Furthermore, maternal education level was positively associated with language skills in the ASD and LR-no ASD groups only. Variability in these early predictors may help explain why language skills are heterogeneous across the autism spectrum, and, with further study, may help clinicians identify those in need of additional and/or specialized intervention services that support language development. LAY SUMMARY: The present study identified predictors of language skills in infants with and without autism spectrum disorder (ASD). Maternal education level and 12-month gesture abilities predicted 3-year language skills in infants with ASD. Measuring these predictors early in life may help identify infants and families in need of additional and/or specialized intervention services that support language development. En ligne : http://dx.doi.org/10.1002/aur.2760 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477 [article] Early predictors of language skills at 3?years of age vary based on diagnostic outcome: A baby siblings research consortium study [Texte imprimé et/ou numérique] / Meredith PECUKONIS, Auteur ; Gregory S. YOUNG, Auteur ; Jessica BRIAN, Auteur ; Tony CHARMAN, Auteur ; Katarzyna CHAWARSKA, Auteur ; Mayada ELSABBAGH, Auteur ; Jana M. IVERSON, Auteur ; Shafali JESTE, Auteur ; Rebecca LANDA, Auteur ; Daniel S. MESSINGER, Auteur ; A. J. SCHWICHTENBERG, Auteur ; Sara Jane WEBB, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Helen TAGER-FLUSBERG, Auteur . - p.1324-1335. Langues : Anglais (eng) in Autism Research > 15-7 (July 2022) . - p.1324-1335 Mots-clés : gesture  infant sibling  language  maternal education  motor  nonverbal cognition Index. décimale : PER Périodiques Résumé : While previous work has identified the early predictors of language skills in infants at elevated familial risk (ER) and low familial risk (LR) for autism spectrum disorder (ASD), no studies to date have explored whether these predictors vary based on diagnostic outcome of ASD or no ASD. The present study used a large, multisite dataset to examine associations between a set of commonly studied predictor variables (infant gesture abilities, fine motor skills, nonverbal cognition, and maternal education level), measured at 12?months, and language skills, measured at 3?years, across three diagnostic outcome groups-infants with ASD ("ASD"), ER infants without ASD ("ER-no ASD"), and LR infants without ASD ("LR-no ASD"). Findings revealed that the predictors of language skills differed across groups, as gesture abilities were positively associated with language skills in the ER-no ASD group but negatively associated with language skills in the ASD group. Furthermore, maternal education level was positively associated with language skills in the ASD and LR-no ASD groups only. Variability in these early predictors may help explain why language skills are heterogeneous across the autism spectrum, and, with further study, may help clinicians identify those in need of additional and/or specialized intervention services that support language development. LAY SUMMARY: The present study identified predictors of language skills in infants with and without autism spectrum disorder (ASD). Maternal education level and 12-month gesture abilities predicted 3-year language skills in infants with ASD. Measuring these predictors early in life may help identify infants and families in need of additional and/or specialized intervention services that support language development. En ligne : http://dx.doi.org/10.1002/aur.2760 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477

Early sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study / Daniel S. MESSINGER in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-12 Titre : Early sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study Type de document : Texte imprimé et/ou numérique Auteurs : Daniel S. MESSINGER, Auteur ; Gregory S. YOUNG, Auteur ; Sara Jane WEBB, Auteur ; Sally OZONOFF, Auteur ; Susan E. BRYSON, Auteur ; Alice S. CARTER, Auteur ; Leslie J. CARVER, Auteur ; Tony CHARMAN, Auteur ; Katarzyna CHAWARSKA, Auteur ; Suzanne CURTIN, Auteur ; Karen DOBKINS, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Ted HUTMAN, Auteur ; Jana M. IVERSON, Auteur ; Rebecca LANDA, Auteur ; Charles A. NELSON, Auteur ; Wendy L. STONE, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Lonnie ZWAIGENBAUM, Auteur Article en page(s) : p.1-12 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The increased male prevalence of autism spectrum disorder (ASD) may be mirrored by the early emergence of sex differences in ASD symptoms and cognitive functioning. The female protective effect hypothesis posits that ASD recurrence and symptoms will be higher among relatives of female probands. This study examined sex differences and sex of proband differences in ASD outcome and in the development of ASD symptoms and cognitive functioning among the high-risk younger siblings of ASD probands and low-risk children. En ligne : http://dx.doi.org/10.1186/s13229-015-0027-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Early sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study [Texte imprimé et/ou numérique] / Daniel S. MESSINGER, Auteur ; Gregory S. YOUNG, Auteur ; Sara Jane WEBB, Auteur ; Sally OZONOFF, Auteur ; Susan E. BRYSON, Auteur ; Alice S. CARTER, Auteur ; Leslie J. CARVER, Auteur ; Tony CHARMAN, Auteur ; Katarzyna CHAWARSKA, Auteur ; Suzanne CURTIN, Auteur ; Karen DOBKINS, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Ted HUTMAN, Auteur ; Jana M. IVERSON, Auteur ; Rebecca LANDA, Auteur ; Charles A. NELSON, Auteur ; Wendy L. STONE, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Lonnie ZWAIGENBAUM, Auteur . - p.1-12. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-12 Index. décimale : PER Périodiques Résumé : The increased male prevalence of autism spectrum disorder (ASD) may be mirrored by the early emergence of sex differences in ASD symptoms and cognitive functioning. The female protective effect hypothesis posits that ASD recurrence and symptoms will be higher among relatives of female probands. This study examined sex differences and sex of proband differences in ASD outcome and in the development of ASD symptoms and cognitive functioning among the high-risk younger siblings of ASD probands and low-risk children. En ligne : http://dx.doi.org/10.1186/s13229-015-0027-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

EEG functional connectivity in infants at elevated familial likelihood for autism spectrum disorder / Scott HUBERTY ; Stefon VAN NOORDT ; James DESJARDINS ; Nicky WRIGHT ; Julie SCORAH ; Sara Jane WEBB ; Mayada ELSABBAGH in Molecular Autism, 14 (2023)  

Public ISBD [article]  inMolecular Autism > 14 (2023) . - 37 p. Titre : EEG functional connectivity in infants at elevated familial likelihood for autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Scott HUBERTY, Auteur ; Stefon VAN NOORDT, Auteur ; James DESJARDINS, Auteur ; Nicky WRIGHT, Auteur ; Julie SCORAH, Auteur ; Sara Jane WEBB, Auteur ; Mayada ELSABBAGH, Auteur Article en page(s) : 37 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : BACKGROUND: Many studies have reported that autism spectrum disorder (ASD) is associated with atypical structural and functional connectivity. However, we know relatively little about the development of these differences in infancy. METHODS: We used a high-density electroencephalogram (EEG) dataset pooled from two independent infant sibling cohorts, to characterize such neurodevelopmental deviations during the first years of life. EEG was recorded at 6 and 12 months of age in infants at typical (N=92) or elevated likelihood for ASD (N=90), determined by the presence of an older sibling with ASD. We computed the functional connectivity between cortical sources of EEG during video watching using the corrected imaginary part of phase-locking values. RESULTS: Our main analysis found no significant association between functional connectivity and ASD, showing only significant effects for age, sex, age-sex interaction, and site. Given these null results, we performed an exploratory analysis and observed, at 12 months, a negative correlation between functional connectivity and ADOS calibrated severity scores for restrictive and repetitive behaviors (RRB). LIMITATIONS: The small sample of ASD participants inherent to sibling studies limits diagnostic group comparisons. Also, results from our secondary exploratory analysis should be considered only as potential relationships to further explore, given their increased vulnerability to false positives. CONCLUSIONS: These results are inconclusive concerning an association between EEG functional connectivity and ASD in infancy. Exploratory analyses provided preliminary support for a relationship between RRB and functional connectivity specifically, but these preliminary observations need corroboration on larger samples. En ligne : http://dx.doi.org/10.1186/s13229-023-00570-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=513 [article] EEG functional connectivity in infants at elevated familial likelihood for autism spectrum disorder [Texte imprimé et/ou numérique] / Scott HUBERTY, Auteur ; Stefon VAN NOORDT, Auteur ; James DESJARDINS, Auteur ; Nicky WRIGHT, Auteur ; Julie SCORAH, Auteur ; Sara Jane WEBB, Auteur ; Mayada ELSABBAGH, Auteur . - 37 p. Langues : Anglais (eng) in Molecular Autism > 14 (2023) . - 37 p. Index. décimale : PER Périodiques Résumé : BACKGROUND: Many studies have reported that autism spectrum disorder (ASD) is associated with atypical structural and functional connectivity. However, we know relatively little about the development of these differences in infancy. METHODS: We used a high-density electroencephalogram (EEG) dataset pooled from two independent infant sibling cohorts, to characterize such neurodevelopmental deviations during the first years of life. EEG was recorded at 6 and 12 months of age in infants at typical (N=92) or elevated likelihood for ASD (N=90), determined by the presence of an older sibling with ASD. We computed the functional connectivity between cortical sources of EEG during video watching using the corrected imaginary part of phase-locking values. RESULTS: Our main analysis found no significant association between functional connectivity and ASD, showing only significant effects for age, sex, age-sex interaction, and site. Given these null results, we performed an exploratory analysis and observed, at 12 months, a negative correlation between functional connectivity and ADOS calibrated severity scores for restrictive and repetitive behaviors (RRB). LIMITATIONS: The small sample of ASD participants inherent to sibling studies limits diagnostic group comparisons. Also, results from our secondary exploratory analysis should be considered only as potential relationships to further explore, given their increased vulnerability to false positives. CONCLUSIONS: These results are inconclusive concerning an association between EEG functional connectivity and ASD in infancy. Exploratory analyses provided preliminary support for a relationship between RRB and functional connectivity specifically, but these preliminary observations need corroboration on larger samples. En ligne : http://dx.doi.org/10.1186/s13229-023-00570-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=513

Electrophysiological Research on Autism / Sara Jane WEBB

Public ISBD in Autism Spectrum Disorders / David G. AMARAL Titre : Electrophysiological Research on Autism Type de document : Texte imprimé et/ou numérique Auteurs : Sara Jane WEBB, Auteur ; Raphael BERNIER, Auteur ; Karen M. BURNER, Auteur ; Michael MURIAS, Auteur Année de publication : 2011 Importance : p.651-663 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139 in Autism Spectrum Disorders / David G. AMARAL Electrophysiological Research on Autism [Texte imprimé et/ou numérique] / Sara Jane WEBB, Auteur ; Raphael BERNIER, Auteur ; Karen M. BURNER, Auteur ; Michael MURIAS, Auteur . - 2011 . - p.651-663. Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139

Exemplaires

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Evaluation of clinical assessments of social abilities for use in autism clinical trials by the autism biomarkers consortium for clinical trials / Susan FAJA in Autism Research, 16-5 (May 2023)  

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Family planning and family vision in mothers after diagnosis of a child with autism spectrum disorder / Noa NAVOT in Autism, 20-5 (July 2016)  

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Fear-Potentiated Startle Response Is Unrelated to Social or Emotional Functioning in Adolescents With Autism Spectrum Disorders / Lindsey STERLING in Autism Research, 6-5 (October 2013)  

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From Toddlers to Adults: The Changing Landscape of the Brain in Autism / Eric COURCHESNE

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Frontal EEG alpha asymmetry in youth with autism: Sex differences and social-emotional correlates / Megha SANTHOSH ; Anna KRESSE ; Elizabeth AYLWARD ; Raphael BERNIER ; Susan BOOKHEIMER ; Shafali JESTE ; Allison JACK ; James C. MCPARTLAND ; Adam NAPLES ; John D. VAN HORN ; Kevin PELPHREY ; Sara Jane WEBB ; ACE GENDAAR NETWORK in Autism Research, 16-12 (December 2023)  

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Guidelines and Best Practices for Electrophysiological Data Collection, Analysis and Reporting in Autism / Sara Jane WEBB in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

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Impairments in social memory in autism? Evidence from behaviour and neuroimaging / Sara Jane WEBB

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Increased alpha power in autistic adults: Relation to sensory behaviors and cortical volume / Scott O. MURRAY ; Daniela L. Seczon ; Mark Pettet ; Hannah M. REA ; Kristin M. WOODARD ; Tamar KOLODNY ; Sara Jane WEBB in Autism Research, 18-1 (January 2025)  

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Neurologic Aspects of Autism / Nancy J. MINSHEW

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Non-ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study / Tony CHARMAN in Autism Research, 10-1 (January 2017)  

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