Atypical Response to Caregiver Touch in Infants at High Risk for Autism Spectrum Disorder / Girija KADLASKAR in Journal of Autism and Developmental Disorders, 49-7 (July 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2946-2955 Titre : Atypical Response to Caregiver Touch in Infants at High Risk for Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Girija KADLASKAR, Auteur ; A. SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; C. A. NELSON, Auteur ; B. KEEHN, Auteur Article en page(s) : p.2946-2955 Langues : Anglais (eng) Mots-clés : Attentional disengagement  Autism  Infant siblings  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Atypical response to tactile input is associated with greater socio-communicative impairments in individuals with autism spectrum disorder (ASD). The current study examined overt orienting to caregiver-initiated touch in 12-month-olds at high risk for ASD (HRA) with (HRA+) and without (HRA-) a later diagnosis of ASD compared to low-risk comparison infants. Findings indicate that infants that go on to receive a diagnosis of ASD may more frequently fail to shift their attention in response to caregiver touch and when they do, they may be more likely to orient away from touch. Additionally, failure to respond to touch predicts ADOS severity scores at outcome suggesting that atypical response to touch may be an early indicator of autism severity. En ligne : http://dx.doi.org/10.1007/s10803-019-04021-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 [article] Atypical Response to Caregiver Touch in Infants at High Risk for Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Girija KADLASKAR, Auteur ; A. SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; C. A. NELSON, Auteur ; B. KEEHN, Auteur . - p.2946-2955. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2946-2955 Mots-clés : Attentional disengagement  Autism  Infant siblings  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Atypical response to tactile input is associated with greater socio-communicative impairments in individuals with autism spectrum disorder (ASD). The current study examined overt orienting to caregiver-initiated touch in 12-month-olds at high risk for ASD (HRA) with (HRA+) and without (HRA-) a later diagnosis of ASD compared to low-risk comparison infants. Findings indicate that infants that go on to receive a diagnosis of ASD may more frequently fail to shift their attention in response to caregiver touch and when they do, they may be more likely to orient away from touch. Additionally, failure to respond to touch predicts ADOS severity scores at outcome suggesting that atypical response to touch may be an early indicator of autism severity. En ligne : http://dx.doi.org/10.1007/s10803-019-04021-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402

Auditory Attentional Disengagement in Children with Autism Spectrum Disorder / B. KEEHN in Journal of Autism and Developmental Disorders, 49-10 (October 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-10 (October 2019) . - p.3999-4008 Titre : Auditory Attentional Disengagement in Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : B. KEEHN, Auteur ; Girija KADLASKAR, Auteur ; R. MCNALLY KEEHN, Auteur ; A. L. FRANCIS, Auteur Article en page(s) : p.3999-4008 Langues : Anglais (eng) Mots-clés : Attention  Auditory  Autism spectrum disorder  Disengagement  Eog  Eye movements Index. décimale : PER Périodiques Résumé : Despite early differences in orienting to sounds, no study to date has investigated whether children with ASD demonstrate impairments in attentional disengagement in the auditory modality. Twenty-one 9-15-year-old children with ASD and 20 age- and IQ-matched TD children were presented with an auditory gap-overlap paradigm. Evidence of impaired disengagement in ASD was mixed. Differences in saccadic reaction time for overlap and gap conditions did not differ between groups. However, children with ASD did show increased no-shift trials in the overlap condition, as well as reduced disengagement efficiency compared to their TD peers. These results provide further support for disengagement impairments in ASD, and suggest that these deficits include disengaging from and shifting to unimodal auditory information. En ligne : http://dx.doi.org/10.1007/s10803-019-04111-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406 [article] Auditory Attentional Disengagement in Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / B. KEEHN, Auteur ; Girija KADLASKAR, Auteur ; R. MCNALLY KEEHN, Auteur ; A. L. FRANCIS, Auteur . - p.3999-4008. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-10 (October 2019) . - p.3999-4008 Mots-clés : Attention  Auditory  Autism spectrum disorder  Disengagement  Eog  Eye movements Index. décimale : PER Périodiques Résumé : Despite early differences in orienting to sounds, no study to date has investigated whether children with ASD demonstrate impairments in attentional disengagement in the auditory modality. Twenty-one 9-15-year-old children with ASD and 20 age- and IQ-matched TD children were presented with an auditory gap-overlap paradigm. Evidence of impaired disengagement in ASD was mixed. Differences in saccadic reaction time for overlap and gap conditions did not differ between groups. However, children with ASD did show increased no-shift trials in the overlap condition, as well as reduced disengagement efficiency compared to their TD peers. These results provide further support for disengagement impairments in ASD, and suggest that these deficits include disengaging from and shifting to unimodal auditory information. En ligne : http://dx.doi.org/10.1007/s10803-019-04111-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406

Brief Report: Reduced Heart Rate Variability in Children with Autism Spectrum Disorder / Catharine LORY in Journal of Autism and Developmental Disorders, 50-11 (November 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-11 (November 2020) . - p.4183-4190 Titre : Brief Report: Reduced Heart Rate Variability in Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Catharine LORY, Auteur ; Girija KADLASKAR, Auteur ; Rebecca MCNALLY KEEHN, Auteur ; Alexander L FRANCIS, Auteur ; Brandon KEEHN, Auteur Article en page(s) : p.4183-4190 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Autonomic arousal  Ecg  Heart rate variability Index. décimale : PER Périodiques Résumé : Dysregulation of the autonomic nervous system (ANS), which can be indexed by heart rate variability (HRV), has been posited to contribute to core features of autism spectrum disorder (ASD). However, the relationship between ASD and HRV remains uncertain. We assessed tonic and phasic HRV of 21 children with ASD and 21 age- and IQ-matched typically developing (TD) children and examined (1) group differences in HRV and (2) associations between HRV and ASD symptomatology. Children with ASD showed significantly lower tonic HRV, but similar phasic HRV compared to TD children. Additionally, reduced tonic HRV was associated with atypical attentional responsivity in ASD. Our findings suggest ANS dysregulation is present in ASD and may contribute to atypical attentional responses to sensory stimulation. En ligne : http://dx.doi.org/10.1007/s10803-020-04458-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432 [article] Brief Report: Reduced Heart Rate Variability in Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Catharine LORY, Auteur ; Girija KADLASKAR, Auteur ; Rebecca MCNALLY KEEHN, Auteur ; Alexander L FRANCIS, Auteur ; Brandon KEEHN, Auteur . - p.4183-4190. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-11 (November 2020) . - p.4183-4190 Mots-clés : Autism spectrum disorder  Autonomic arousal  Ecg  Heart rate variability Index. décimale : PER Périodiques Résumé : Dysregulation of the autonomic nervous system (ANS), which can be indexed by heart rate variability (HRV), has been posited to contribute to core features of autism spectrum disorder (ASD). However, the relationship between ASD and HRV remains uncertain. We assessed tonic and phasic HRV of 21 children with ASD and 21 age- and IQ-matched typically developing (TD) children and examined (1) group differences in HRV and (2) associations between HRV and ASD symptomatology. Children with ASD showed significantly lower tonic HRV, but similar phasic HRV compared to TD children. Additionally, reduced tonic HRV was associated with atypical attentional responsivity in ASD. Our findings suggest ANS dysregulation is present in ASD and may contribute to atypical attentional responses to sensory stimulation. En ligne : http://dx.doi.org/10.1007/s10803-020-04458-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432

Caregiver Touch-Speech Communication and Infant Responses in 12-Month-Olds at High Risk for Autism Spectrum Disorder / Girija KADLASKAR in Journal of Autism and Developmental Disorders, 50-3 (March 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.1064-1072 Titre : Caregiver Touch-Speech Communication and Infant Responses in 12-Month-Olds at High Risk for Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Girija KADLASKAR, Auteur ; Amanda SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur ; Brandon KEEHN, Auteur Article en page(s) : p.1064-1072 Langues : Anglais (eng) Mots-clés : Autism  Infant siblings  Multimodal input  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Multimodal communication may facilitate attention in infants. This study examined the presentation of caregiver touch-only and touch + speech input to 12-month-olds at high (HRA) and low risk for ASD. Findings indicated that, although both groups received a greater number of touch + speech bouts compared to touch-only bouts, the duration of overall touch that overlapped with speech was significantly greater in the HRA group. Additionally, HRA infants were less responsive to touch-only bouts compared to touch + speech bouts suggesting that their mothers may use more touch + speech communication to elicit infant responses. Nonetheless, the exact role of touch in multimodal communication directed towards infants at high risk for ASD warrants further exploration. En ligne : http://dx.doi.org/10.1007/s10803-019-04310-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420 [article] Caregiver Touch-Speech Communication and Infant Responses in 12-Month-Olds at High Risk for Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Girija KADLASKAR, Auteur ; Amanda SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur ; Brandon KEEHN, Auteur . - p.1064-1072. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.1064-1072 Mots-clés : Autism  Infant siblings  Multimodal input  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Multimodal communication may facilitate attention in infants. This study examined the presentation of caregiver touch-only and touch + speech input to 12-month-olds at high (HRA) and low risk for ASD. Findings indicated that, although both groups received a greater number of touch + speech bouts compared to touch-only bouts, the duration of overall touch that overlapped with speech was significantly greater in the HRA group. Additionally, HRA infants were less responsive to touch-only bouts compared to touch + speech bouts suggesting that their mothers may use more touch + speech communication to elicit infant responses. Nonetheless, the exact role of touch in multimodal communication directed towards infants at high risk for ASD warrants further exploration. En ligne : http://dx.doi.org/10.1007/s10803-019-04310-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420

Measures of tonic and phasic activity of the locus coeruleus-norepinephrine system in children with autism spectrum disorder: An event-related potential and pupillometry study / Yesol KIM in Autism Research, 15-12 (December 2022)  

Public ISBD [article]  inAutism Research > 15-12 (December 2022) . - p.2250-2264 Titre : Measures of tonic and phasic activity of the locus coeruleus-norepinephrine system in children with autism spectrum disorder: An event-related potential and pupillometry study Type de document : Texte imprimé et/ou numérique Auteurs : Yesol KIM, Auteur ; Girija KADLASKAR, Auteur ; Rebecca McNally KEEHN, Auteur ; Brandon KEEHN, Auteur Article en page(s) : p.2250-2264 Langues : Anglais (eng) Mots-clés : Child  Humans  Locus Coeruleus  Autism Spectrum Disorder  Norepinephrine  Attention/physiology  Evoked Potentials  autism spectrum disorder  electrophysiology  eye-tracking  locus coeruleus Index. décimale : PER Périodiques Résumé : A growing body of research suggests that locus coeruleus-norepinephrine (LC-NE) system may function differently in individuals with autism spectrum disorder (ASD). Understanding the dynamics of both tonic (resting pupil diameter) and phasic (pupil dilation response [PDR] and event-related potential [ERP]) indices may provide meaningful insights about the nature of LC-NE function in ASD. Twenty-four children with ASD and 27 age- and nonverbal-IQ matched typically developing (TD) children completed two experiments: (1) a resting eye-tracking task to measure tonic pupil diameter, and (2) a three-stimulus oddball paradigm to measure phasic responsivity using PDR and ERP. Consistent with prior reports, our results indicate that children with ASD exhibit increased tonic (resting pupil diameter) and reduced phasic (PDR and ERP) activity of the LC-NE system compared to their TD peers. For both groups, decreased phasic responsivity was associated with increased resting pupil diameter. Lastly, tonic and phasic LC-NE indices were primarily related to measures of attention-deficit/hyperactivity disorder (ADHD), and not ASD, symptomatology. These findings expand our understanding of neurophysiological differences present in ASD and demonstrate that aberrant LC-NE activation may be associated with atypical arousal and decreased responsivity to behaviorally-relevant information in ASD. En ligne : http://dx.doi.org/10.1002/aur.2820 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 [article] Measures of tonic and phasic activity of the locus coeruleus-norepinephrine system in children with autism spectrum disorder: An event-related potential and pupillometry study [Texte imprimé et/ou numérique] / Yesol KIM, Auteur ; Girija KADLASKAR, Auteur ; Rebecca McNally KEEHN, Auteur ; Brandon KEEHN, Auteur . - p.2250-2264. Langues : Anglais (eng) in Autism Research > 15-12 (December 2022) . - p.2250-2264 Mots-clés : Child  Humans  Locus Coeruleus  Autism Spectrum Disorder  Norepinephrine  Attention/physiology  Evoked Potentials  autism spectrum disorder  electrophysiology  eye-tracking  locus coeruleus Index. décimale : PER Périodiques Résumé : A growing body of research suggests that locus coeruleus-norepinephrine (LC-NE) system may function differently in individuals with autism spectrum disorder (ASD). Understanding the dynamics of both tonic (resting pupil diameter) and phasic (pupil dilation response [PDR] and event-related potential [ERP]) indices may provide meaningful insights about the nature of LC-NE function in ASD. Twenty-four children with ASD and 27 age- and nonverbal-IQ matched typically developing (TD) children completed two experiments: (1) a resting eye-tracking task to measure tonic pupil diameter, and (2) a three-stimulus oddball paradigm to measure phasic responsivity using PDR and ERP. Consistent with prior reports, our results indicate that children with ASD exhibit increased tonic (resting pupil diameter) and reduced phasic (PDR and ERP) activity of the LC-NE system compared to their TD peers. For both groups, decreased phasic responsivity was associated with increased resting pupil diameter. Lastly, tonic and phasic LC-NE indices were primarily related to measures of attention-deficit/hyperactivity disorder (ADHD), and not ASD, symptomatology. These findings expand our understanding of neurophysiological differences present in ASD and demonstrate that aberrant LC-NE activation may be associated with atypical arousal and decreased responsivity to behaviorally-relevant information in ASD. En ligne : http://dx.doi.org/10.1002/aur.2820 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488

Patterns of sensory processing in young children with autism: Differences in autism characteristics, adaptive skills, and attentional problems / Girija KADLASKAR in Autism, 27-3 (April 2023)  

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