Across the continuum of attention skills: a twin study of the SWAN ADHD rating scale / Tinca J.C. POLDERMAN in Journal of Child Psychology and Psychiatry, 48-11 (November 2007)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 48-11 (November 2007) . - p.1080–1087 Titre : Across the continuum of attention skills: a twin study of the SWAN ADHD rating scale Type de document : texte imprimé Auteurs : Tinca J.C. POLDERMAN, Auteur ; James J. HUDZIAK, Auteur ; Dorret I. BOOMSMA, Auteur ; Frank C. VERHULST, Auteur ; Eske M. DERKS, Auteur ; Daniëlle POSTHUMA, Auteur Année de publication : 2007 Article en page(s) : p.1080–1087 Langues : Anglais (eng) Mots-clés : Attention-deficit hyperactivity heritability twin study Index. décimale : PER Périodiques Résumé : Most behavior checklists for attention problems or attention deficit/hyperactivity disorder (ADHD) such as the Child Behavior Checklist (CBCL) have a narrow range of scores, focusing on the extent to which problems are present. It has been proposed that measuring attention on a continuum, from positive attention skills to attention problems, will add value to our understanding of ADHD and related problems. The Strengths and Weaknesses of ADHD symptoms and Normal behavior scale (SWAN) is such a scale. Items of the SWAN are scored on a seven-point scale, with in the middle ‘average behavior’ and on the extremes ‘far below average’ and ‘far above average’. Method: The SWAN and the CBCL were completed by mothers of respectively 560 and 469 12-year-old twin pairs. The SWAN consists of nine DSM-IV items for Attention Deficit (AD) and nine DSM-IV items for Hyperactivity/Impulsivity (HI). The CBCL Attention Problem (AP) scale consists of 11 items, which are rated on a three-point scale. Results: Children who had a score of zero on the CBCL AP scale can be further differentiated using the SWAN, with variation seen between the average behavior and far above average range. In addition, SWAN scores were normally distributed, rather than kurtotic or skewed as is often seen with other behavioral checklists. The CBCL AP scale and the SWAN-HI and AD scale were strongly influenced by genetic factors (73%, 90% and 82%, respectively). However, there were striking differences in genetic architecture: variation in CBCL AP scores is in large part explained by non-additive genetic influences. Variation in SWAN scores is explained by additive genetic influences only. Conclusion: Ratings on the SWAN cover the continuum from positive attention skills to attention and hyperactivity problems that define ADHD. Instruments such as the SWAN offer clinicians and researchers the opportunity to examine variation in both strengths and weaknesses in attention skills. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01783.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297 [article] Across the continuum of attention skills: a twin study of the SWAN ADHD rating scale [texte imprimé] / Tinca J.C. POLDERMAN, Auteur ; James J. HUDZIAK, Auteur ; Dorret I. BOOMSMA, Auteur ; Frank C. VERHULST, Auteur ; Eske M. DERKS, Auteur ; Daniëlle POSTHUMA, Auteur . - 2007 . - p.1080–1087. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 48-11 (November 2007) . - p.1080–1087 Mots-clés : Attention-deficit hyperactivity heritability twin study Index. décimale : PER Périodiques Résumé : Most behavior checklists for attention problems or attention deficit/hyperactivity disorder (ADHD) such as the Child Behavior Checklist (CBCL) have a narrow range of scores, focusing on the extent to which problems are present. It has been proposed that measuring attention on a continuum, from positive attention skills to attention problems, will add value to our understanding of ADHD and related problems. The Strengths and Weaknesses of ADHD symptoms and Normal behavior scale (SWAN) is such a scale. Items of the SWAN are scored on a seven-point scale, with in the middle ‘average behavior’ and on the extremes ‘far below average’ and ‘far above average’. Method: The SWAN and the CBCL were completed by mothers of respectively 560 and 469 12-year-old twin pairs. The SWAN consists of nine DSM-IV items for Attention Deficit (AD) and nine DSM-IV items for Hyperactivity/Impulsivity (HI). The CBCL Attention Problem (AP) scale consists of 11 items, which are rated on a three-point scale. Results: Children who had a score of zero on the CBCL AP scale can be further differentiated using the SWAN, with variation seen between the average behavior and far above average range. In addition, SWAN scores were normally distributed, rather than kurtotic or skewed as is often seen with other behavioral checklists. The CBCL AP scale and the SWAN-HI and AD scale were strongly influenced by genetic factors (73%, 90% and 82%, respectively). However, there were striking differences in genetic architecture: variation in CBCL AP scores is in large part explained by non-additive genetic influences. Variation in SWAN scores is explained by additive genetic influences only. Conclusion: Ratings on the SWAN cover the continuum from positive attention skills to attention and hyperactivity problems that define ADHD. Instruments such as the SWAN offer clinicians and researchers the opportunity to examine variation in both strengths and weaknesses in attention skills. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01783.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297

Adults with autism spectrum disorder show atypical patterns of thoughts and feelings during rest / Sonja SIMPRAGA in Autism, 25-5 (July 2021)  

Public ISBD [article]  inAutism > 25-5 (July 2021) . - p.1433-1443 Titre : Adults with autism spectrum disorder show atypical patterns of thoughts and feelings during rest Type de document : texte imprimé Auteurs : Sonja SIMPRAGA, Auteur ; Ricarda F. WEILAND, Auteur ; Huibert D. MANSVELDER, Auteur ; Tinca J.C. POLDERMAN, Auteur ; Sander BEGEER, Auteur ; Dirk Ja SMIT, Auteur ; Klaus LINKENKAER-HANSEN, Auteur Article en page(s) : p.1433-1443 Langues : Anglais (eng) Mots-clés : Adult  Autism Spectrum Disorder  Emotions  Humans  Imagination  Social Behavior  Surveys and Questionnaires  amsterdam resting-state questionnaire  autism  mind wandering  resting-state Index. décimale : PER Périodiques Résumé : Everyone knows the feeling of letting one's mind wander freely in a quiet moment. The thoughts and feelings experienced in those moments have been shown to influence our well-being-and vice versa. In this study, we looked at which thoughts and feelings are being experienced by adults with autism spectrum disorder and compared them to adults without autism spectrum disorder. In total, 88 adults with autism spectrum disorder and 90 adults without autism spectrum disorder were asked to rest for 5 min with their eyes closed and let their mind wander. Directly after, they filled in the Amsterdam Resting-State Questionnaire, which probes what participants were feeling and thinking during the period of rest. We found that adults with autism spectrum disorder tend to think less about others, felt less comfortable, and had more disrupted thoughts during the rest compared to adults without autism spectrum disorder. Interestingly, autism spectrum disorder participants reporting lower levels of comfort during the rest also reported more autism spectrum disorder symptoms, specifically in social behaviors and skills, attention switching, and imagination. We propose to use the eyes-closed rest condition in combination with the Amsterdam Resting-State Questionnaire more widely to shed light on aberrant thoughts and feelings in brain disorders and to study the effect of therapeutic interventions. En ligne : http://dx.doi.org/10.1177/1362361321990928 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475 [article] Adults with autism spectrum disorder show atypical patterns of thoughts and feelings during rest [texte imprimé] / Sonja SIMPRAGA, Auteur ; Ricarda F. WEILAND, Auteur ; Huibert D. MANSVELDER, Auteur ; Tinca J.C. POLDERMAN, Auteur ; Sander BEGEER, Auteur ; Dirk Ja SMIT, Auteur ; Klaus LINKENKAER-HANSEN, Auteur . - p.1433-1443. Langues : Anglais (eng) in Autism > 25-5 (July 2021) . - p.1433-1443 Mots-clés : Adult  Autism Spectrum Disorder  Emotions  Humans  Imagination  Social Behavior  Surveys and Questionnaires  amsterdam resting-state questionnaire  autism  mind wandering  resting-state Index. décimale : PER Périodiques Résumé : Everyone knows the feeling of letting one's mind wander freely in a quiet moment. The thoughts and feelings experienced in those moments have been shown to influence our well-being-and vice versa. In this study, we looked at which thoughts and feelings are being experienced by adults with autism spectrum disorder and compared them to adults without autism spectrum disorder. In total, 88 adults with autism spectrum disorder and 90 adults without autism spectrum disorder were asked to rest for 5 min with their eyes closed and let their mind wander. Directly after, they filled in the Amsterdam Resting-State Questionnaire, which probes what participants were feeling and thinking during the period of rest. We found that adults with autism spectrum disorder tend to think less about others, felt less comfortable, and had more disrupted thoughts during the rest compared to adults without autism spectrum disorder. Interestingly, autism spectrum disorder participants reporting lower levels of comfort during the rest also reported more autism spectrum disorder symptoms, specifically in social behaviors and skills, attention switching, and imagination. We propose to use the eyes-closed rest condition in combination with the Amsterdam Resting-State Questionnaire more widely to shed light on aberrant thoughts and feelings in brain disorders and to study the effect of therapeutic interventions. En ligne : http://dx.doi.org/10.1177/1362361321990928 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475

Adults with autism spectrum disorder show atypical patterns of thoughts and feelings during rest / Sonja SIMPRAGA in Autism, 26-5 (July 2022)  

Public ISBD [article]  inAutism > 26-5 (July 2022) . - p.1433-1443 Titre : Adults with autism spectrum disorder show atypical patterns of thoughts and feelings during rest Type de document : texte imprimé Auteurs : Sonja SIMPRAGA, Auteur ; Ricarda F. WEILAND, Auteur ; Huibert D. MANSVELDER, Auteur ; Tinca J.C. POLDERMAN, Auteur ; Sander BEGEER, Auteur ; Dirk Ja SMIT, Auteur ; Klaus LINKENKAER-HANSEN, Auteur Article en page(s) : p.1433-1443 Langues : Anglais (eng) Mots-clés : Adult  Autism Spectrum Disorder  Emotions  Humans  Imagination  Social Behavior  Surveys and Questionnaires  amsterdam resting-state questionnaire  autism  mind wandering  resting-state Index. décimale : PER Périodiques Résumé : Everyone knows the feeling of letting one's mind wander freely in a quiet moment. The thoughts and feelings experienced in those moments have been shown to influence our well-being-and vice versa. In this study, we looked at which thoughts and feelings are being experienced by adults with autism spectrum disorder and compared them to adults without autism spectrum disorder. In total, 88 adults with autism spectrum disorder and 90 adults without autism spectrum disorder were asked to rest for 5min with their eyes closed and let their mind wander. Directly after, they filled in the Amsterdam Resting-State Questionnaire, which probes what participants were feeling and thinking during the period of rest. We found that adults with autism spectrum disorder tend to think less about others, felt less comfortable, and had more disrupted thoughts during the rest compared to adults without autism spectrum disorder. Interestingly, autism spectrum disorder participants reporting lower levels of comfort during the rest also reported more autism spectrum disorder symptoms, specifically in social behaviors and skills, attention switching, and imagination. We propose to use the eyes-closed rest condition in combination with the Amsterdam Resting-State Questionnaire more widely to shed light on aberrant thoughts and feelings in brain disorders and to study the effect of therapeutic interventions. En ligne : http://dx.doi.org/10.1177/1362361321990928 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=484 [article] Adults with autism spectrum disorder show atypical patterns of thoughts and feelings during rest [texte imprimé] / Sonja SIMPRAGA, Auteur ; Ricarda F. WEILAND, Auteur ; Huibert D. MANSVELDER, Auteur ; Tinca J.C. POLDERMAN, Auteur ; Sander BEGEER, Auteur ; Dirk Ja SMIT, Auteur ; Klaus LINKENKAER-HANSEN, Auteur . - p.1433-1443. Langues : Anglais (eng) in Autism > 26-5 (July 2022) . - p.1433-1443 Mots-clés : Adult  Autism Spectrum Disorder  Emotions  Humans  Imagination  Social Behavior  Surveys and Questionnaires  amsterdam resting-state questionnaire  autism  mind wandering  resting-state Index. décimale : PER Périodiques Résumé : Everyone knows the feeling of letting one's mind wander freely in a quiet moment. The thoughts and feelings experienced in those moments have been shown to influence our well-being-and vice versa. In this study, we looked at which thoughts and feelings are being experienced by adults with autism spectrum disorder and compared them to adults without autism spectrum disorder. In total, 88 adults with autism spectrum disorder and 90 adults without autism spectrum disorder were asked to rest for 5min with their eyes closed and let their mind wander. Directly after, they filled in the Amsterdam Resting-State Questionnaire, which probes what participants were feeling and thinking during the period of rest. We found that adults with autism spectrum disorder tend to think less about others, felt less comfortable, and had more disrupted thoughts during the rest compared to adults without autism spectrum disorder. Interestingly, autism spectrum disorder participants reporting lower levels of comfort during the rest also reported more autism spectrum disorder symptoms, specifically in social behaviors and skills, attention switching, and imagination. We propose to use the eyes-closed rest condition in combination with the Amsterdam Resting-State Questionnaire more widely to shed light on aberrant thoughts and feelings in brain disorders and to study the effect of therapeutic interventions. En ligne : http://dx.doi.org/10.1177/1362361321990928 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=484

No differences between adults with and without autism in audiovisual synchrony perception / Ricarda F. WEILAND in Autism, 27-4 (May 2023)  

Public ISBD [article]  inAutism > 27-4 (May 2023) . - p.927-937 Titre : No differences between adults with and without autism in audiovisual synchrony perception Type de document : texte imprimé Auteurs : Ricarda F. WEILAND, Auteur ; Tinca J.C. POLDERMAN, Auteur ; Dirk Ja SMIT, Auteur ; Sander BEGEER, Auteur ; Erik VAN DER BURG, Auteur Article en page(s) : p.927-937 Langues : Anglais (eng) Mots-clés : autism,multisensory,predictive processing,rapid temporal recalibration,temporal binding Index. décimale : PER Périodiques Résumé : To facilitate multisensory processing, the brain binds multisensory information when presented within a certain maximum time lag (temporal binding window). In addition, and in audiovisual perception specifically, the brain adapts rapidly to asynchronies within a single trial and shifts the point of subjective simultaneity. Both processes, temporal binding and rapid recalibration, have been found to be altered in individuals with an autism spectrum disorder diagnosis. Here, we used a large adult sample (autism spectrum disorder: n=75, no autism spectrum disorder: n=85) to replicate these earlier findings. In this study, audiovisual stimuli were presented in a random order across a range of stimulus onset asynchronies, and participants indicated whether they were perceived simultaneously. Based on the synchrony distribution, their individual temporal binding window and point of subjective simultaneity were calculated. Contrary to previous findings, we found that the temporal binding window was not significantly different between both groups. Rapid recalibration was observed for both groups but did not differ significantly between groups. Evidence of an age effect was found which might explain discrepancies to previous studies. In addition, neither temporal binding window nor rapid recalibration was correlated with self-reported autistic symptoms or sensory sensitivity.Lay abstractIt has been known for a long time that individuals diagnosed with autism spectrum disorder perceive the world differently. In this study, we investigated how people with or without autism perceive visual and auditory information. We know that an auditory and a visual stimulus do not have to be perfectly synchronous for us to perceive them as synchronous: first, when the two are within a certain time window (temporal binding window), the brain will tell us that they are synchronous. Second, the brain can also adapt quickly to audiovisual asynchronies (rapid recalibration). Although previous studies have shown that people with autism spectrum disorder have different temporal binding windows, and less rapid recalibration, we did not find these differences in our study. However, we did find that both processes develop over age, and since previous studies tested only young people (children, adolescents, and young adults), and we tested adults from 18 to 55 years, this might explain the different findings. In the end, there might be quite a complex story, where people with and without autism spectrum disorder perceive the world differently, even dependent on how old they are. En ligne : https://doi.org/10.1177/13623613221121414 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499 [article] No differences between adults with and without autism in audiovisual synchrony perception [texte imprimé] / Ricarda F. WEILAND, Auteur ; Tinca J.C. POLDERMAN, Auteur ; Dirk Ja SMIT, Auteur ; Sander BEGEER, Auteur ; Erik VAN DER BURG, Auteur . - p.927-937. Langues : Anglais (eng) in Autism > 27-4 (May 2023) . - p.927-937 Mots-clés : autism,multisensory,predictive processing,rapid temporal recalibration,temporal binding Index. décimale : PER Périodiques Résumé : To facilitate multisensory processing, the brain binds multisensory information when presented within a certain maximum time lag (temporal binding window). In addition, and in audiovisual perception specifically, the brain adapts rapidly to asynchronies within a single trial and shifts the point of subjective simultaneity. Both processes, temporal binding and rapid recalibration, have been found to be altered in individuals with an autism spectrum disorder diagnosis. Here, we used a large adult sample (autism spectrum disorder: n=75, no autism spectrum disorder: n=85) to replicate these earlier findings. In this study, audiovisual stimuli were presented in a random order across a range of stimulus onset asynchronies, and participants indicated whether they were perceived simultaneously. Based on the synchrony distribution, their individual temporal binding window and point of subjective simultaneity were calculated. Contrary to previous findings, we found that the temporal binding window was not significantly different between both groups. Rapid recalibration was observed for both groups but did not differ significantly between groups. Evidence of an age effect was found which might explain discrepancies to previous studies. In addition, neither temporal binding window nor rapid recalibration was correlated with self-reported autistic symptoms or sensory sensitivity.Lay abstractIt has been known for a long time that individuals diagnosed with autism spectrum disorder perceive the world differently. In this study, we investigated how people with or without autism perceive visual and auditory information. We know that an auditory and a visual stimulus do not have to be perfectly synchronous for us to perceive them as synchronous: first, when the two are within a certain time window (temporal binding window), the brain will tell us that they are synchronous. Second, the brain can also adapt quickly to audiovisual asynchronies (rapid recalibration). Although previous studies have shown that people with autism spectrum disorder have different temporal binding windows, and less rapid recalibration, we did not find these differences in our study. However, we did find that both processes develop over age, and since previous studies tested only young people (children, adolescents, and young adults), and we tested adults from 18 to 55 years, this might explain the different findings. In the end, there might be quite a complex story, where people with and without autism spectrum disorder perceive the world differently, even dependent on how old they are. En ligne : https://doi.org/10.1177/13623613221121414 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499

Polygenic scores for schizophrenia and educational attainment are associated with behavioural problems in early childhood in the general population / Philip R. JANSEN in Journal of Child Psychology and Psychiatry, 59-1 (January 2018)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 59-1 (January 2018) . - p.39-47 Titre : Polygenic scores for schizophrenia and educational attainment are associated with behavioural problems in early childhood in the general population Type de document : texte imprimé Auteurs : Philip R. JANSEN, Auteur ; Tinca J.C. POLDERMAN, Auteur ; Koen BOLHUIS, Auteur ; Jan VAN DER ENDE, Auteur ; Vincent W.V. JADDOE, Auteur ; Frank C. VERHULST, Auteur ; Tonya WHITE, Auteur ; Daniëlle POSTHUMA, Auteur ; Henning TIEMEIER, Auteur Article en page(s) : p.39-47 Langues : Anglais (eng) Mots-clés : Polygenic scores  psychiatric disorders  educational attainment  childhood behaviour Index. décimale : PER Périodiques Résumé : Background Genome-wide association studies in adults have identified numerous genetic variants related to psychiatric disorders and related traits, such as schizophrenia and educational attainment. However, the effects of these genetic variants on behaviour in the general population remain to be fully understood, particularly in younger populations. We investigated whether polygenic scores of five psychiatric disorders and educational attainment are related to emotional and behaviour problems during early childhood. Methods From the Generation R Study, we included participants with available genotype data and behavioural problems measured with the Child Behavior Checklist (CBCL) at the age of 3 (n = 1,902), 6 (n = 2,202) and 10 years old (n = 1,843). Polygenic scores were calculated for five psychiatric disorders and educational attainment. These polygenic scores were tested for an association with the broadband internalizing and externalizing problem scales and the specific CBCL syndrome scale scores. Results Analysis of the CBCL broadband scales showed that the schizophrenia polygenic score was associated with significantly higher internalizing scores at 3, 6 and 10 years and higher externalizing scores at age 3 and 6. The educational attainment polygenic score was associated with lower externalizing scores at all time points and lower internalizing scores at age 3. No associations were observed for the polygenic scores of bipolar disorder, major depressive disorder and autism spectrum disorder. Secondary analyses of specific syndrome scores showed that the schizophrenia polygenic score was strongly related to the Thought Problems scores. A negative association was observed between the educational attainment polygenic score and Attention Problems scores across all age groups. Conclusions Polygenic scores for adult psychiatric disorders and educational attainment are associated with variation in emotional and behavioural problems already at a very early age. En ligne : http://dx.doi.org/10.1111/jcpp.12759 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=327 [article] Polygenic scores for schizophrenia and educational attainment are associated with behavioural problems in early childhood in the general population [texte imprimé] / Philip R. JANSEN, Auteur ; Tinca J.C. POLDERMAN, Auteur ; Koen BOLHUIS, Auteur ; Jan VAN DER ENDE, Auteur ; Vincent W.V. JADDOE, Auteur ; Frank C. VERHULST, Auteur ; Tonya WHITE, Auteur ; Daniëlle POSTHUMA, Auteur ; Henning TIEMEIER, Auteur . - p.39-47. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 59-1 (January 2018) . - p.39-47 Mots-clés : Polygenic scores  psychiatric disorders  educational attainment  childhood behaviour Index. décimale : PER Périodiques Résumé : Background Genome-wide association studies in adults have identified numerous genetic variants related to psychiatric disorders and related traits, such as schizophrenia and educational attainment. However, the effects of these genetic variants on behaviour in the general population remain to be fully understood, particularly in younger populations. We investigated whether polygenic scores of five psychiatric disorders and educational attainment are related to emotional and behaviour problems during early childhood. Methods From the Generation R Study, we included participants with available genotype data and behavioural problems measured with the Child Behavior Checklist (CBCL) at the age of 3 (n = 1,902), 6 (n = 2,202) and 10 years old (n = 1,843). Polygenic scores were calculated for five psychiatric disorders and educational attainment. These polygenic scores were tested for an association with the broadband internalizing and externalizing problem scales and the specific CBCL syndrome scale scores. Results Analysis of the CBCL broadband scales showed that the schizophrenia polygenic score was associated with significantly higher internalizing scores at 3, 6 and 10 years and higher externalizing scores at age 3 and 6. The educational attainment polygenic score was associated with lower externalizing scores at all time points and lower internalizing scores at age 3. No associations were observed for the polygenic scores of bipolar disorder, major depressive disorder and autism spectrum disorder. Secondary analyses of specific syndrome scores showed that the schizophrenia polygenic score was strongly related to the Thought Problems scores. A negative association was observed between the educational attainment polygenic score and Attention Problems scores across all age groups. Conclusions Polygenic scores for adult psychiatric disorders and educational attainment are associated with variation in emotional and behavioural problems already at a very early age. En ligne : http://dx.doi.org/10.1111/jcpp.12759 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=327

Research Review: A review of the past decade of family and genomic studies on adolescent mental health / Elisavet PALAIOLOGOU ; Tinca J.C. POLDERMAN ; Thalia C. ELEY in Journal of Child Psychology and Psychiatry, 66-6 (June 2025)  

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The Dutch Sensory Perception Quotient-Short in adults with and without autism / Ricarda F. WEILAND in Autism, 24-8 (November 2020)  

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The predictive capacity of psychiatric and psychological polygenic risk scores for distinguishing cases in a child and adolescent psychiatric sample from controls / Arija G. JANSEN in Journal of Child Psychology and Psychiatry, 62-9 (September 2021)  

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