Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence / Giorgia MICHELINI in Journal of Child Psychology and Psychiatry, 56-4 (April 2015)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 56-4 (April 2015) . - p.423-431 Titre : Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Giorgia MICHELINI, Auteur ; Thalia C. ELEY, Auteur ; Alice M. GREGORY, Auteur ; Tom A. MCADAMS, Auteur Article en page(s) : p.423-431 Langues : Anglais (eng) Mots-clés : Anxiety  ADH problems  genetics  twins  adolescence Index. décimale : PER Périodiques Résumé : Background Anxiety and attention-deficit/hyperactivity (ADH) problems are common in adolescence, often co-occur, and are characterised by high heterogeneity in their phenotypic expressions. Although it is known that anxiety and ADH problems correlate, the relationships between subtypes of anxiety and ADH problems have been scarcely investigated. Methods Using a large population sample of adolescent twins and siblings we explored the phenotypic and aetiological association between anxiety subtypes (panic/agoraphobia, separation anxiety, social anxiety, physical injury fears, obsessive-compulsive symptoms and generalised anxiety) and the two ADH dimensions (attention problems and hyperactivity/impulsivity). Both phenotypes were assessed using self-report questionnaires. Results The association between ADH problems and anxiety could be entirely attributed to attention problems, not hyperactivity/impulsivity. Most of the correlations between anxiety subtypes and attention problems showed an approximately equal role of genetic and nonshared environmental factors. Conclusions The high heterogeneity within anxiety and ADH problems should be taken into account in order to better understand comorbidity between them. En ligne : http://dx.doi.org/10.1111/jcpp.12318 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 [article] Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence [Texte imprimé et/ou numérique] / Giorgia MICHELINI, Auteur ; Thalia C. ELEY, Auteur ; Alice M. GREGORY, Auteur ; Tom A. MCADAMS, Auteur . - p.423-431. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 56-4 (April 2015) . - p.423-431 Mots-clés : Anxiety  ADH problems  genetics  twins  adolescence Index. décimale : PER Périodiques Résumé : Background Anxiety and attention-deficit/hyperactivity (ADH) problems are common in adolescence, often co-occur, and are characterised by high heterogeneity in their phenotypic expressions. Although it is known that anxiety and ADH problems correlate, the relationships between subtypes of anxiety and ADH problems have been scarcely investigated. Methods Using a large population sample of adolescent twins and siblings we explored the phenotypic and aetiological association between anxiety subtypes (panic/agoraphobia, separation anxiety, social anxiety, physical injury fears, obsessive-compulsive symptoms and generalised anxiety) and the two ADH dimensions (attention problems and hyperactivity/impulsivity). Both phenotypes were assessed using self-report questionnaires. Results The association between ADH problems and anxiety could be entirely attributed to attention problems, not hyperactivity/impulsivity. Most of the correlations between anxiety subtypes and attention problems showed an approximately equal role of genetic and nonshared environmental factors. Conclusions The high heterogeneity within anxiety and ADH problems should be taken into account in order to better understand comorbidity between them. En ligne : http://dx.doi.org/10.1111/jcpp.12318 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260

Assessing gene–environment interactions on anxiety symptom subtypes across childhood and adolescence / Jennifer Y.F. LAU in Development and Psychopathology, 19-4 (Fall 2007)  

Public ISBD [article]  inDevelopment and Psychopathology > 19-4 (Fall 2007) . - p.1129-1146 Titre : Assessing gene–environment interactions on anxiety symptom subtypes across childhood and adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Jennifer Y.F. LAU, Auteur ; Daniel Samuel PINE, Auteur ; Thalia C. ELEY, Auteur ; Alice M. GREGORY, Auteur ; Michelle A. GOLDWIN, Auteur Année de publication : 2007 Article en page(s) : p.1129-1146 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Consistent evidence shows both genetic and stress-related risks on child and adolescent anxiety, yet few studies have considered the degree to which genetic effects are moderated by stress (gene–environment interaction). We used longitudinal data from both a child and adolescent sample of twins to examine three novel issues on the presence of gene–environment interaction on anxiety symptoms. First, we assessed moderation of genetic risks on anxiety symptoms by negative life events in each age group. Second, by distinguishing between “stable” and “age-specific” genetic factors, we explored the continuity of gene–environment interaction across time and/or its emergence at specific ages. Third, we compared the presence of gene–environment interaction across different symptom types (general, panic, social, and separation). Genetic effects on separation anxiety symptoms in childhood (mean age = 8 years, 6 months) and panic anxiety symptoms in adolescence (mean age = 15 years) increased across independent negative life events. Shared environmental effects on separation anxiety symptoms and nonshared environmental effects on general anxiety symptoms in adolescence were also moderated by negative life events. We interpret these preliminary findings tentatively in the context of gene–environment interaction on anxiety in general, and on early separation and later panic anxiety in particular. En ligne : http://dx.doi.org/10.1017/s0954579407000582 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=182 [article] Assessing gene–environment interactions on anxiety symptom subtypes across childhood and adolescence [Texte imprimé et/ou numérique] / Jennifer Y.F. LAU, Auteur ; Daniel Samuel PINE, Auteur ; Thalia C. ELEY, Auteur ; Alice M. GREGORY, Auteur ; Michelle A. GOLDWIN, Auteur . - 2007 . - p.1129-1146. Langues : Anglais (eng) in Development and Psychopathology > 19-4 (Fall 2007) . - p.1129-1146 Index. décimale : PER Périodiques Résumé : Consistent evidence shows both genetic and stress-related risks on child and adolescent anxiety, yet few studies have considered the degree to which genetic effects are moderated by stress (gene–environment interaction). We used longitudinal data from both a child and adolescent sample of twins to examine three novel issues on the presence of gene–environment interaction on anxiety symptoms. First, we assessed moderation of genetic risks on anxiety symptoms by negative life events in each age group. Second, by distinguishing between “stable” and “age-specific” genetic factors, we explored the continuity of gene–environment interaction across time and/or its emergence at specific ages. Third, we compared the presence of gene–environment interaction across different symptom types (general, panic, social, and separation). Genetic effects on separation anxiety symptoms in childhood (mean age = 8 years, 6 months) and panic anxiety symptoms in adolescence (mean age = 15 years) increased across independent negative life events. Shared environmental effects on separation anxiety symptoms and nonshared environmental effects on general anxiety symptoms in adolescence were also moderated by negative life events. We interpret these preliminary findings tentatively in the context of gene–environment interaction on anxiety in general, and on early separation and later panic anxiety in particular. En ligne : http://dx.doi.org/10.1017/s0954579407000582 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=182

Associations between the parent–child relationship and adolescent self-worth: a genetically informed study of twin parents and their adolescent children / Tom A. MCADAMS in Journal of Child Psychology and Psychiatry, 58-1 (January 2017)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 58-1 (January 2017) . - p.46-54 Titre : Associations between the parent–child relationship and adolescent self-worth: a genetically informed study of twin parents and their adolescent children Type de document : Texte imprimé et/ou numérique Auteurs : Tom A. MCADAMS, Auteur ; Frühling V. RIJSDIJK, Auteur ; Jurgita NARUSYTE, Auteur ; Jody M. GANIBAN, Auteur ; David REISS, Auteur ; Erica SPOTTS, Auteur ; Jenae M. NEIDERHISER, Auteur ; Paul LICHTENSTEIN, Auteur ; Thalia C. ELEY, Auteur Article en page(s) : p.46-54 Langues : Anglais (eng) Mots-clés : Adolescence  parenting  parent–child relationships  children-of-twins  self-esteem Index. décimale : PER Périodiques Résumé : Background Low self-worth during adolescence predicts a range of emotional and behavioural problems. As such, identifying potential sources of influence on self-worth is important. Aspects of the parent–child relationship are often associated with adolescent self-worth but to date it is unclear whether such associations may be attributable to familial confounding (e.g. genetic relatedness). We set out to clarify the nature of relationships between parental expressed affection and adolescent self-worth, and parent–child closeness and adolescent self-worth. Methods We used data from the Twin and Offspring Study in Sweden, a children-of-twins sample comprising 909 adult twin pairs with adolescent children. Using these data we were able to apply structural equation models with which we could examine whether associations remained after accounting for genetic transmission. Results Results demonstrated that parent–child closeness and parental-expressed affection were both phenotypically associated with adolescent self-worth. Associations could not be attributed to genetic relatedness between parent and child. Conclusions Parent–child closeness and parental affection are associated with adolescent self-worth above and beyond effects attributable to genetic relatedness. Data were cross-sectional, so the direction of effects cannot be confirmed but findings support the notion that positive parent–child relationships increase adolescent self-worth. En ligne : http://dx.doi.org/10.1111/jcpp.12600 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 [article] Associations between the parent–child relationship and adolescent self-worth: a genetically informed study of twin parents and their adolescent children [Texte imprimé et/ou numérique] / Tom A. MCADAMS, Auteur ; Frühling V. RIJSDIJK, Auteur ; Jurgita NARUSYTE, Auteur ; Jody M. GANIBAN, Auteur ; David REISS, Auteur ; Erica SPOTTS, Auteur ; Jenae M. NEIDERHISER, Auteur ; Paul LICHTENSTEIN, Auteur ; Thalia C. ELEY, Auteur . - p.46-54. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 58-1 (January 2017) . - p.46-54 Mots-clés : Adolescence  parenting  parent–child relationships  children-of-twins  self-esteem Index. décimale : PER Périodiques Résumé : Background Low self-worth during adolescence predicts a range of emotional and behavioural problems. As such, identifying potential sources of influence on self-worth is important. Aspects of the parent–child relationship are often associated with adolescent self-worth but to date it is unclear whether such associations may be attributable to familial confounding (e.g. genetic relatedness). We set out to clarify the nature of relationships between parental expressed affection and adolescent self-worth, and parent–child closeness and adolescent self-worth. Methods We used data from the Twin and Offspring Study in Sweden, a children-of-twins sample comprising 909 adult twin pairs with adolescent children. Using these data we were able to apply structural equation models with which we could examine whether associations remained after accounting for genetic transmission. Results Results demonstrated that parent–child closeness and parental-expressed affection were both phenotypically associated with adolescent self-worth. Associations could not be attributed to genetic relatedness between parent and child. Conclusions Parent–child closeness and parental affection are associated with adolescent self-worth above and beyond effects attributable to genetic relatedness. Data were cross-sectional, so the direction of effects cannot be confirmed but findings support the notion that positive parent–child relationships increase adolescent self-worth. En ligne : http://dx.doi.org/10.1111/jcpp.12600 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298

Attentional threat avoidance and familial risk are independently associated with childhood anxiety disorders / Hannah M. BROWN in Journal of Child Psychology and Psychiatry, 54-6 (June 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-6 (June 2013) . - p.678-685 Titre : Attentional threat avoidance and familial risk are independently associated with childhood anxiety disorders Type de document : Texte imprimé et/ou numérique Auteurs : Hannah M. BROWN, Auteur ; Tom A. MCADAMS, Auteur ; Kathryn J. LESTER, Auteur ; Robert GOODMAN, Auteur ; David M. CLARK, Auteur ; Thalia C. ELEY, Auteur Article en page(s) : p.678-685 Langues : Anglais (eng) Mots-clés : Anxiety  attention  children  familial risk Index. décimale : PER Périodiques Résumé : Background: Twin studies in children reveal that familial aggregation of anxiety disorders is due to both genetic and environmental factors. Cognitive biases for threat information are considered a robust characteristic of childhood anxiety. However, little is known regarding the underlying aetiology of such biases and their role in anxiety disorders. Method: A face version of the dot-probe task measuring attentional biases for negative (anger, fear, sad, disgust) and positive (happy) facial expressions was completed by 600, 8-year-old twins; the largest study of its kind. Twin correlations for attentional bias scores were compared to estimate genetic and environmental effects. Parent-report diagnostic interviews identified children with an anxiety disorder. Indices of inferred genetic and familial risk for anxiety disorders were created for each child. Data were analysed using a series of logistic regressions. Results: Anxious children showed greater attentional avoidance of negative faces than nonanxious children; t (548) = 2.55, p .05. Attentional avoidance was not under genetic or shared environmental influence. Risk for anxiety disorders was predicted by familial factors. Both attentional avoidance and inferred familial risk were significant but independent predictors of anxiety disorders (ORs = .65 and 3.64, respectively). Conclusions: Anxiety-related attentional biases and familial risk play important but independent roles in childhood anxiety disorders. If replicated, these findings indicate that links between genetic risk and anxiety disorders lie outside the domain of attentional processes. En ligne : http://dx.doi.org/10.1111/jcpp.12024 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=200 [article] Attentional threat avoidance and familial risk are independently associated with childhood anxiety disorders [Texte imprimé et/ou numérique] / Hannah M. BROWN, Auteur ; Tom A. MCADAMS, Auteur ; Kathryn J. LESTER, Auteur ; Robert GOODMAN, Auteur ; David M. CLARK, Auteur ; Thalia C. ELEY, Auteur . - p.678-685. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-6 (June 2013) . - p.678-685 Mots-clés : Anxiety  attention  children  familial risk Index. décimale : PER Périodiques Résumé : Background: Twin studies in children reveal that familial aggregation of anxiety disorders is due to both genetic and environmental factors. Cognitive biases for threat information are considered a robust characteristic of childhood anxiety. However, little is known regarding the underlying aetiology of such biases and their role in anxiety disorders. Method: A face version of the dot-probe task measuring attentional biases for negative (anger, fear, sad, disgust) and positive (happy) facial expressions was completed by 600, 8-year-old twins; the largest study of its kind. Twin correlations for attentional bias scores were compared to estimate genetic and environmental effects. Parent-report diagnostic interviews identified children with an anxiety disorder. Indices of inferred genetic and familial risk for anxiety disorders were created for each child. Data were analysed using a series of logistic regressions. Results: Anxious children showed greater attentional avoidance of negative faces than nonanxious children; t (548) = 2.55, p .05. Attentional avoidance was not under genetic or shared environmental influence. Risk for anxiety disorders was predicted by familial factors. Both attentional avoidance and inferred familial risk were significant but independent predictors of anxiety disorders (ORs = .65 and 3.64, respectively). Conclusions: Anxiety-related attentional biases and familial risk play important but independent roles in childhood anxiety disorders. If replicated, these findings indicate that links between genetic risk and anxiety disorders lie outside the domain of attentional processes. En ligne : http://dx.doi.org/10.1111/jcpp.12024 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=200

A cross-lagged twin study of emotional symptoms, social isolation and peer victimisation from early adolescence to emerging adulthood / Geneviève MORNEAU-VAILLANCOURT in Journal of Child Psychology and Psychiatry, 64-11 (November 2023)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 64-11 (November 2023) . - p.1569-1582 Titre : A cross-lagged twin study of emotional symptoms, social isolation and peer victimisation from early adolescence to emerging adulthood Type de document : Texte imprimé et/ou numérique Auteurs : Geneviève MORNEAU-VAILLANCOURT, Auteur ; Olakunle OGINNI, Auteur ; Elham ASSARY, Auteur ; Georgina KREBS, Auteur ; Ellen J. THOMPSON, Auteur ; Elisavet PALAIOLOGOU, Auteur ; Celestine LOCKHART, Auteur ; Louise ARSENEAULT, Auteur ; Thalia C. ELEY, Auteur Article en page(s) : p.1569-1582 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Emotional symptoms, such as anxiety and depressive symptoms, are common during adolescence, often persist over time, and can precede the emergence of severe anxiety and depressive disorders. Studies suggest that a vicious cycle of reciprocal influences between emotional symptoms and interpersonal difficulties may explain why some adolescents suffer from persisting emotional symptoms. However, the role of different types of interpersonal difficulties, such as social isolation and peer victimisation, in these reciprocal associations is still unclear. In addition, the lack of longitudinal twin studies conducted on emotional symptoms during adolescence means that the genetic and environmental contributions to these relationships during adolescence remain unknown. Methods Participants (N=15,869) from the Twins Early Development Study completed self-reports of emotional symptoms, social isolation and peer victimisation at 12, 16 and 21?years old. A phenotypic cross-lagged model examined reciprocal associations between variables over time, and a genetic extension of this model examined the aetiology of the relationships between variables at each timepoint. Results First, emotional symptoms were reciprocally and independently associated with both social isolation and peer victimisation over time, indicating that different forms of interpersonal difficulties uniquely contributed to emotional symptoms during adolescence and vice versa. Second, early peer victimisation predicted later emotional symptoms via social isolation in mid-adolescence, indicating that social isolation may constitute an intermediate pathway through which peer victimisation predicts longer-term emotional symptoms. Finally, individual differences in emotional symptoms were mostly accounted for by non-shared environmental factors at each timepoint, and both gene-environment and individual-specific environmental mechanisms were involved in the relationships between emotional symptoms and interpersonal difficulties. Conclusions Our study highlights the necessity to intervene early in adolescence to prevent the escalation of emotional symptoms over time and to consider social isolation and peer victimisation as important risk factors for the long-term persistence of emotional symptoms. En ligne : https://doi.org/10.1111/jcpp.13847 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512 [article] A cross-lagged twin study of emotional symptoms, social isolation and peer victimisation from early adolescence to emerging adulthood [Texte imprimé et/ou numérique] / Geneviève MORNEAU-VAILLANCOURT, Auteur ; Olakunle OGINNI, Auteur ; Elham ASSARY, Auteur ; Georgina KREBS, Auteur ; Ellen J. THOMPSON, Auteur ; Elisavet PALAIOLOGOU, Auteur ; Celestine LOCKHART, Auteur ; Louise ARSENEAULT, Auteur ; Thalia C. ELEY, Auteur . - p.1569-1582. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 64-11 (November 2023) . - p.1569-1582 Index. décimale : PER Périodiques Résumé : Background Emotional symptoms, such as anxiety and depressive symptoms, are common during adolescence, often persist over time, and can precede the emergence of severe anxiety and depressive disorders. Studies suggest that a vicious cycle of reciprocal influences between emotional symptoms and interpersonal difficulties may explain why some adolescents suffer from persisting emotional symptoms. However, the role of different types of interpersonal difficulties, such as social isolation and peer victimisation, in these reciprocal associations is still unclear. In addition, the lack of longitudinal twin studies conducted on emotional symptoms during adolescence means that the genetic and environmental contributions to these relationships during adolescence remain unknown. Methods Participants (N=15,869) from the Twins Early Development Study completed self-reports of emotional symptoms, social isolation and peer victimisation at 12, 16 and 21?years old. A phenotypic cross-lagged model examined reciprocal associations between variables over time, and a genetic extension of this model examined the aetiology of the relationships between variables at each timepoint. Results First, emotional symptoms were reciprocally and independently associated with both social isolation and peer victimisation over time, indicating that different forms of interpersonal difficulties uniquely contributed to emotional symptoms during adolescence and vice versa. Second, early peer victimisation predicted later emotional symptoms via social isolation in mid-adolescence, indicating that social isolation may constitute an intermediate pathway through which peer victimisation predicts longer-term emotional symptoms. Finally, individual differences in emotional symptoms were mostly accounted for by non-shared environmental factors at each timepoint, and both gene-environment and individual-specific environmental mechanisms were involved in the relationships between emotional symptoms and interpersonal difficulties. Conclusions Our study highlights the necessity to intervene early in adolescence to prevent the escalation of emotional symptoms over time and to consider social isolation and peer victimisation as important risk factors for the long-term persistence of emotional symptoms. En ligne : https://doi.org/10.1111/jcpp.13847 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512

Developmental change in the association between adolescent depressive symptoms and the home environment: results from a longitudinal, genetically informative investigation / Laurie J. HANNIGAN in Journal of Child Psychology and Psychiatry, 58-7 (July 2017)  

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Developmental trajectories of child and adolescent emotional problems: associations with early adult alcohol use behaviors / Tong CHEN in Journal of Child Psychology and Psychiatry, 66-1 (January 2025)  

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Disentangling gene-environment correlations and interactions on adolescent depressive symptoms / Jennifer Y.F. LAU in Journal of Child Psychology and Psychiatry, 49-2 (February 2008)  

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Does childhood anxiety evoke maternal control? A genetically informed study / Thalia C. ELEY in Journal of Child Psychology and Psychiatry, 51-7 (July 2010)  

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Editorial / Thalia C. ELEY in Journal of Child Psychology and Psychiatry, 47-7 (July 2006)  

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Editorial: ‘The time has come,’ the Walrus said, ‘To speak of many things; Of shoes and ships and sealing wax, Of cabbages and kings.’ / Thalia C. ELEY in Journal of Child Psychology and Psychiatry, 48-6 (June 2007)  

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Editorial: Work-in-progress: towards DSM-V / Thalia C. ELEY in Journal of Child Psychology and Psychiatry, 49-1 (January 2008)  

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Explaining the influence of non-shared environment (NSE) on symptoms of behaviour problems from preschool to adulthood: mind the missing NSE gap / Agnieszka GIDZIELA in Journal of Child Psychology and Psychiatry, 64-5 (May 2023)  

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Exploring the Covariation between Anxiety and Depression Symptoms: A Genetic Analysis of the Effects of Age and Sex / Thalia C. ELEY in Journal of Child Psychology and Psychiatry, 40-8 (November 1999)

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Feeling anxious: a twin study of panic/somatic ratings, anxiety sensitivity and heartbeat perception in children / Thalia C. ELEY in Journal of Child Psychology and Psychiatry, 48-12 (December 2007)  

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