Parental concerns of children with ASD by age: A qualitative analysis / Danika PFEIFFER in Research in Autism Spectrum Disorders, 86 (August 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 86 (August 2021) . - 101817 Titre : Parental concerns of children with ASD by age: A qualitative analysis Type de document : Texte imprimé et/ou numérique Auteurs : Danika PFEIFFER, Auteur ; Calliope HOLINGUE, Auteur ; Emily DILLON, Auteur ; Luke G. KALB, Auteur ; Rachel REETZKE, Auteur ; Rebecca LANDA, Auteur Article en page(s) : 101817 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Parental concerns  Children  Age  Qualitative Index. décimale : PER Périodiques Résumé : Background Eliciting parents’ concerns about their children is an important initial step in the ASD diagnostic process. This information is often collected through forced-choice questionnaires utilizing professional terminology and may limit the potential concerns that can be reported. Parent concern studies to date have largely used deductive qualitative methods with only one age group of children. Inductive qualitative studies are needed to examine parental concerns of children with ASD across age groups with one coding scheme. Method We used an inductive qualitative analysis process to analyze concerns reported by parents of children ages 1–11 years on intake forms (n = 455) at an urban outpatient ASD specialty clinic. Analyses were based on three age groups (toddler, preschooler, middle childhood). Results Using conventional content analysis, 12 categories of concerns emerged from parents’ responses: communication, social, behavioral/emotional, cognition, life skills, atypical behaviors, sensory, academic, health, seeking diagnostic clarity or resources, developmental, and motor skills. We found that parents reported the same concerns about their children across age groups in six of the 12 categories. The biggest difference in reported concerns across age groups was that parents of children in the preschooler and middle childhood groups reported a greater number of concerns related to mental health than parents of toddlers. Conclusion Our analysis yields specific information about similarities and differences in parents’ concerns depending on their child’s age. Ensuring that ASD evaluations are tailored to children’s unique needs has implications for timely diagnosis and access to care. En ligne : https://doi.org/10.1016/j.rasd.2021.101817 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] Parental concerns of children with ASD by age: A qualitative analysis [Texte imprimé et/ou numérique] / Danika PFEIFFER, Auteur ; Calliope HOLINGUE, Auteur ; Emily DILLON, Auteur ; Luke G. KALB, Auteur ; Rachel REETZKE, Auteur ; Rebecca LANDA, Auteur . - 101817. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 86 (August 2021) . - 101817 Mots-clés : Autism spectrum disorders  Parental concerns  Children  Age  Qualitative Index. décimale : PER Périodiques Résumé : Background Eliciting parents’ concerns about their children is an important initial step in the ASD diagnostic process. This information is often collected through forced-choice questionnaires utilizing professional terminology and may limit the potential concerns that can be reported. Parent concern studies to date have largely used deductive qualitative methods with only one age group of children. Inductive qualitative studies are needed to examine parental concerns of children with ASD across age groups with one coding scheme. Method We used an inductive qualitative analysis process to analyze concerns reported by parents of children ages 1–11 years on intake forms (n = 455) at an urban outpatient ASD specialty clinic. Analyses were based on three age groups (toddler, preschooler, middle childhood). Results Using conventional content analysis, 12 categories of concerns emerged from parents’ responses: communication, social, behavioral/emotional, cognition, life skills, atypical behaviors, sensory, academic, health, seeking diagnostic clarity or resources, developmental, and motor skills. We found that parents reported the same concerns about their children across age groups in six of the 12 categories. The biggest difference in reported concerns across age groups was that parents of children in the preschooler and middle childhood groups reported a greater number of concerns related to mental health than parents of toddlers. Conclusion Our analysis yields specific information about similarities and differences in parents’ concerns depending on their child’s age. Ensuring that ASD evaluations are tailored to children’s unique needs has implications for timely diagnosis and access to care. En ligne : https://doi.org/10.1016/j.rasd.2021.101817 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

Prevalence of gastrointestinal symptoms among autistic individuals, with and without co-occurring intellectual disability / Calliope HOLINGUE in Autism Research, 16-8 (August 2023)  

Public ISBD [article]  inAutism Research > 16-8 (August 2023) . - p.1609-1618 Titre : Prevalence of gastrointestinal symptoms among autistic individuals, with and without co-occurring intellectual disability Type de document : Texte imprimé et/ou numérique Auteurs : Calliope HOLINGUE, Auteur ; Danika PFEIFFER, Auteur ; Natasha N. LUDWIG, Auteur ; Rachel REETZKE, Auteur ; Ji Su HONG, Auteur ; Luther G. KALB, Auteur ; Rebecca LANDA, Auteur Article en page(s) : p.1609-1618 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Gastrointestinal symptoms (GI) are very common among individuals on the autism spectrum. Prior research reports mixed findings regarding whether individuals with autism and co-occurring intellectual disability (ID) have elevated risk of gastrointestinal symptoms relative to individuals with autism alone. GI symptoms can be challenging to assess in individuals with autism spectrum disorder (ASD) and/or ID given challenges with language, communication, and interoception. Prior research has tended to only include individuals with documented presence or absence of GI symptoms or conditions, that is, to exclude observations in which there is uncertainty regarding presence of GI symptoms. Therefore, none of the prior autism studies reported the association between ID and the certainty regarding presence or absence of GI symptoms. The objective of this study was to examine differences in parental certainty and odds of reporting gastrointestinal signs and symptoms among children on the autism spectrum, with and without intellectual disability. Participants were 308 children (36% ID) with a clinical diagnosis of autism spectrum disorder (6-17?years). Parents endorsed whether their child had experienced or displayed a range of signs or symptoms related to GI problems in the past 3 months. Parents of autistic children with ID were less certain about the presence of more subjective symptoms, including abdominal pain, nausea, and bloating. Conversely, certainty regarding more objective signs (e.g., constipation, diarrhea, spitting up, etc.) was not significantly different. More accurate measures for GI signs/symptoms are needed for this population. En ligne : https://doi.org/10.1002/aur.2972 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Prevalence of gastrointestinal symptoms among autistic individuals, with and without co-occurring intellectual disability [Texte imprimé et/ou numérique] / Calliope HOLINGUE, Auteur ; Danika PFEIFFER, Auteur ; Natasha N. LUDWIG, Auteur ; Rachel REETZKE, Auteur ; Ji Su HONG, Auteur ; Luther G. KALB, Auteur ; Rebecca LANDA, Auteur . - p.1609-1618. Langues : Anglais (eng) in Autism Research > 16-8 (August 2023) . - p.1609-1618 Index. décimale : PER Périodiques Résumé : Abstract Gastrointestinal symptoms (GI) are very common among individuals on the autism spectrum. Prior research reports mixed findings regarding whether individuals with autism and co-occurring intellectual disability (ID) have elevated risk of gastrointestinal symptoms relative to individuals with autism alone. GI symptoms can be challenging to assess in individuals with autism spectrum disorder (ASD) and/or ID given challenges with language, communication, and interoception. Prior research has tended to only include individuals with documented presence or absence of GI symptoms or conditions, that is, to exclude observations in which there is uncertainty regarding presence of GI symptoms. Therefore, none of the prior autism studies reported the association between ID and the certainty regarding presence or absence of GI symptoms. The objective of this study was to examine differences in parental certainty and odds of reporting gastrointestinal signs and symptoms among children on the autism spectrum, with and without intellectual disability. Participants were 308 children (36% ID) with a clinical diagnosis of autism spectrum disorder (6-17?years). Parents endorsed whether their child had experienced or displayed a range of signs or symptoms related to GI problems in the past 3 months. Parents of autistic children with ID were less certain about the presence of more subjective symptoms, including abdominal pain, nausea, and bloating. Conversely, certainty regarding more objective signs (e.g., constipation, diarrhea, spitting up, etc.) was not significantly different. More accurate measures for GI signs/symptoms are needed for this population. En ligne : https://doi.org/10.1002/aur.2972 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Replication study for ADOS-2 cut-offs to assist evaluation of autism spectrum disorder / Ji Su HONG in Autism Research, 15-11 (November 2022)  

Public ISBD [article]  inAutism Research > 15-11 (November 2022) . - p.2181-2191 Titre : Replication study for ADOS-2 cut-offs to assist evaluation of autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Ji Su HONG, Auteur ; Vini SINGH, Auteur ; Luke G. KALB, Auteur ; Rachel REETZKE, Auteur ; Natasha N. LUDWIG, Auteur ; Danika PFEIFFER, Auteur ; Calliope HOLINGUE, Auteur ; Deepa MENON, Auteur ; Qing LU, Auteur ; Ahlam ASHKAR, Auteur ; Rebecca LANDA, Auteur Article en page(s) : p.2181-2191 Langues : Anglais (eng) Mots-clés : Child  Humans  Male  Female  Autism Spectrum Disorder/diagnosis  Sensitivity and Specificity  Predictive Value of Tests  Algorithms  Autistic Disorder  autism spectrum disorder  classification  cut-off score  diagnosis Index. décimale : PER Périodiques Résumé : The Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) has been widely used for ASD assessment. While prior studies investigated sensitivity and specificity of ADOS-2 Modules 1-3, there has been limited research addressing algorithm cut-off scores to optimize ADOS-2 classification. The goal of this study was to assess algorithm cut-off scores for diagnosing ASD with Modules 1-3, and to evaluate alignment of the ADOS-2 classification with the best estimate clinical diagnosis. Participants included 3144 children aged 31 months or older who received ADOS-2 Modules 1-3, as well as the best estimate clinical diagnosis. Five classification statistics were reported for each module: sensitivity, specificity, positive predictive value, negative predictive value, and accuracy (i.e., Receiver Operator Classification Statistic), and these statistics were calculated for the optimal cut-off score. Frequency tables were used to compare ADOS-2 classification and the best estimate clinical diagnosis. Half of the sample received Module 3, 21% received Module 2, and 29% received Module 1. The overall prevalence of ASD was 60%; the male-to-female ratio was 4:1, and half of the sample was non-White. Across all modules, the autism spectrum cut-off score from the ADOS-2 manual resulted in high sensitivity (95%+) and low specificity (63%-73%). The autism cut-off score resulted in better specificity (76%-86%) with favorable sensitivity (81%-94%). The optimal cut-off scores for all modules based on the current sample were within the autism spectrum classification range except Module 2 Algorithm 2. In the No ASD group, 29% had false positives (ADOS-2 autism spectrum classification or autism classification). The ADOS-2 autism spectrum classification did not indicate directionality for diagnostic outcome (ASD 56% vs. No ASD 44%). While cut-off scores of ADOS-2 Modules 1-3 in the manual yielded good clinical utility in ASD assessment, false positives and low predictability of the autism spectrum classification remain challenging for clinicians. En ligne : http://dx.doi.org/10.1002/aur.2801 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 [article] Replication study for ADOS-2 cut-offs to assist evaluation of autism spectrum disorder [Texte imprimé et/ou numérique] / Ji Su HONG, Auteur ; Vini SINGH, Auteur ; Luke G. KALB, Auteur ; Rachel REETZKE, Auteur ; Natasha N. LUDWIG, Auteur ; Danika PFEIFFER, Auteur ; Calliope HOLINGUE, Auteur ; Deepa MENON, Auteur ; Qing LU, Auteur ; Ahlam ASHKAR, Auteur ; Rebecca LANDA, Auteur . - p.2181-2191. Langues : Anglais (eng) in Autism Research > 15-11 (November 2022) . - p.2181-2191 Mots-clés : Child  Humans  Male  Female  Autism Spectrum Disorder/diagnosis  Sensitivity and Specificity  Predictive Value of Tests  Algorithms  Autistic Disorder  autism spectrum disorder  classification  cut-off score  diagnosis Index. décimale : PER Périodiques Résumé : The Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) has been widely used for ASD assessment. While prior studies investigated sensitivity and specificity of ADOS-2 Modules 1-3, there has been limited research addressing algorithm cut-off scores to optimize ADOS-2 classification. The goal of this study was to assess algorithm cut-off scores for diagnosing ASD with Modules 1-3, and to evaluate alignment of the ADOS-2 classification with the best estimate clinical diagnosis. Participants included 3144 children aged 31 months or older who received ADOS-2 Modules 1-3, as well as the best estimate clinical diagnosis. Five classification statistics were reported for each module: sensitivity, specificity, positive predictive value, negative predictive value, and accuracy (i.e., Receiver Operator Classification Statistic), and these statistics were calculated for the optimal cut-off score. Frequency tables were used to compare ADOS-2 classification and the best estimate clinical diagnosis. Half of the sample received Module 3, 21% received Module 2, and 29% received Module 1. The overall prevalence of ASD was 60%; the male-to-female ratio was 4:1, and half of the sample was non-White. Across all modules, the autism spectrum cut-off score from the ADOS-2 manual resulted in high sensitivity (95%+) and low specificity (63%-73%). The autism cut-off score resulted in better specificity (76%-86%) with favorable sensitivity (81%-94%). The optimal cut-off scores for all modules based on the current sample were within the autism spectrum classification range except Module 2 Algorithm 2. In the No ASD group, 29% had false positives (ADOS-2 autism spectrum classification or autism classification). The ADOS-2 autism spectrum classification did not indicate directionality for diagnostic outcome (ASD 56% vs. No ASD 44%). While cut-off scores of ADOS-2 Modules 1-3 in the manual yielded good clinical utility in ASD assessment, false positives and low predictability of the autism spectrum classification remain challenging for clinicians. En ligne : http://dx.doi.org/10.1002/aur.2801 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488

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