Commentary: Integrative, multi-level explanatory models are needed to understand recent trends in sex, gender, and internalizing conditions, reflections on Keyes and Platt (2023) / Lilly SHANAHAN in Journal of Child Psychology and Psychiatry, 65-4 (April 2024)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 65-4 (April 2024) . - p.408-412 Titre : Commentary: Integrative, multi-level explanatory models are needed to understand recent trends in sex, gender, and internalizing conditions, reflections on Keyes and Platt (2023) Type de document : texte imprimé Auteurs : Lilly SHANAHAN, Auteur ; William E. COPELAND, Auteur Article en page(s) : p.408-412 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Keyes' and Platt's (The Journal of Child Psychology and Psychiatry, 2023) review provides much-needed systematic evidence about why internalizing symptoms have increased and it clarifies the role of novel risk factors. The findings highlight that multiple factors at multiple levels are responsible for this phenomenon, many with small effects, within a complex interplay that is rarely well captured. As new insights emerge across disciplines, an important step is to renew efforts to integrate them to understand how internalizing symptoms develop for different people. En ligne : https://doi.org/10.1111/jcpp.13957 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523 [article] Commentary: Integrative, multi-level explanatory models are needed to understand recent trends in sex, gender, and internalizing conditions, reflections on Keyes and Platt (2023) [texte imprimé] / Lilly SHANAHAN, Auteur ; William E. COPELAND, Auteur . - p.408-412. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 65-4 (April 2024) . - p.408-412 Index. décimale : PER Périodiques Résumé : Keyes' and Platt's (The Journal of Child Psychology and Psychiatry, 2023) review provides much-needed systematic evidence about why internalizing symptoms have increased and it clarifies the role of novel risk factors. The findings highlight that multiple factors at multiple levels are responsible for this phenomenon, many with small effects, within a complex interplay that is rarely well captured. As new insights emerge across disciplines, an important step is to renew efforts to integrate them to understand how internalizing symptoms develop for different people. En ligne : https://doi.org/10.1111/jcpp.13957 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523

Configurations of common childhood psychosocial risk factors / William E. COPELAND in Journal of Child Psychology and Psychiatry, 50-4 (April 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-4 (April 2009) . - p.451-459 Titre : Configurations of common childhood psychosocial risk factors Type de document : texte imprimé Auteurs : William E. COPELAND, Auteur ; Adrian ANGOLD, Auteur ; E. Jane COSTELLO, Auteur ; Lilly SHANAHAN, Auteur Année de publication : 2009 Article en page(s) : p.451-459 Langues : Anglais (eng) Mots-clés : Psychosocial-risk-factors psychiatric-disorders development sex-differences epidemiology Index. décimale : PER Périodiques Résumé : Background: Co-occurrence of psychosocial risk factors is commonplace, but little is known about psychiatrically-predictive configurations of psychosocial risk factors. Methods: Latent class analysis (LCA) was applied to 17 putative psychosocial risk factors in a representative population sample of 920 children ages 9 to 17. The resultant class structure was retested in a representative population sample of 1420 children aged 9 to 13. In each sample, the child and one parent were interviewed with the Child and Adolescent Psychiatric Assessment. Concurrent psychiatric status was used to validate class membership. Results: LCA identified five latent classes in both samples: two low risk classes; two moderate risk classes both involving family poverty configured with various other risk factors; and a high risk class characterized by family relational dysfunction and parental risk characteristics. Of the primary sample, 48.6% were categorized as low risk, 42.8% as moderate risk, and 8.6% as high risk. Moderate risk classes differed in their prediction of disruptive and emotional disorders depending on their specific risk factor configurations. High risk youth had the highest levels of both emotional and disruptive disorders. Combining our latent classes with a cumulative risk approach best accounted for the effects of risk factors on psychopathology in our primary sample. Conclusions: Particular risk configurations have specific associations with psychiatric disorders. Configurational approaches are an important asset for large-scale epidemiological studies that integrate information about patterns of risk and disorders. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02005.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=723 [article] Configurations of common childhood psychosocial risk factors [texte imprimé] / William E. COPELAND, Auteur ; Adrian ANGOLD, Auteur ; E. Jane COSTELLO, Auteur ; Lilly SHANAHAN, Auteur . - 2009 . - p.451-459. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-4 (April 2009) . - p.451-459 Mots-clés : Psychosocial-risk-factors psychiatric-disorders development sex-differences epidemiology Index. décimale : PER Périodiques Résumé : Background: Co-occurrence of psychosocial risk factors is commonplace, but little is known about psychiatrically-predictive configurations of psychosocial risk factors. Methods: Latent class analysis (LCA) was applied to 17 putative psychosocial risk factors in a representative population sample of 920 children ages 9 to 17. The resultant class structure was retested in a representative population sample of 1420 children aged 9 to 13. In each sample, the child and one parent were interviewed with the Child and Adolescent Psychiatric Assessment. Concurrent psychiatric status was used to validate class membership. Results: LCA identified five latent classes in both samples: two low risk classes; two moderate risk classes both involving family poverty configured with various other risk factors; and a high risk class characterized by family relational dysfunction and parental risk characteristics. Of the primary sample, 48.6% were categorized as low risk, 42.8% as moderate risk, and 8.6% as high risk. Moderate risk classes differed in their prediction of disruptive and emotional disorders depending on their specific risk factor configurations. High risk youth had the highest levels of both emotional and disruptive disorders. Combining our latent classes with a cumulative risk approach best accounted for the effects of risk factors on psychopathology in our primary sample. Conclusions: Particular risk configurations have specific associations with psychiatric disorders. Configurational approaches are an important asset for large-scale epidemiological studies that integrate information about patterns of risk and disorders. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02005.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=723

Diagnostic transitions from childhood to adolescence to early adulthood / William E. COPELAND in Journal of Child Psychology and Psychiatry, 54-7 (July 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.791-799 Titre : Diagnostic transitions from childhood to adolescence to early adulthood Type de document : texte imprimé Auteurs : William E. COPELAND, Auteur ; Carol E. ADAIR, Auteur ; Paul SMETANIN, Auteur ; David STIFF, Auteur ; Carla BRIANTE, Auteur ; Ian COLMAN, Auteur ; David M. FERGUSSON, Auteur ; John HORWOOD, Auteur ; Richie POULTON, Auteur ; E. Jane COSTELLO, Auteur ; Adrian ANGOLD, Auteur Article en page(s) : p.791-799 Langues : Anglais (eng) Mots-clés : Epidemiology  longitudinal  depression  anxiety  behavioral disorders  comorbidity Index. décimale : PER Périodiques Résumé : Background Quantifying diagnostic transitions across development is needed to estimate the long-term burden of mental illness. This study estimated patterns of diagnostic transitions from childhood to adolescence and from adolescence to early adulthood. Methods Patterns of diagnostic transitions were estimated using data from three prospective, longitudinal studies involving close to 20,000 observations of 3,722 participants followed across multiple developmental periods covering ages 9–30. Common DSM psychiatric disorders were assessed in childhood (ages 9–12; two samples), adolescence (ages 13–18; three samples), and early adulthood (ages 19 to age 32; three samples) with structured psychiatric interviews and questionnaires. Results Having a disorder at an early period was associated with at least a threefold increase in odds for having a disorder at a later period. Homotypic and heterotypic transitions were observed for every disorder category. The strongest evidence of continuity was seen for behavioral disorders (particularly ADHD) with less evidence for emotional disorders such as depression and anxiety. Limited evidence was found in adjusted models for behavioral disorders predicting later emotional disorders. Adult substance disorders were preceded by behavioral disorders, but not anxiety or depression. Conclusions Having a disorder in childhood or adolescence is a potent risk factor for a range of psychiatric problems later in development. These findings provide further support for prevention and early life intervention efforts and suggest that treatment at younger ages, while justified in its own right, may also have potential to reduce the risk for disorders later in development. En ligne : http://dx.doi.org/10.1111/jcpp.12062 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=203 [article] Diagnostic transitions from childhood to adolescence to early adulthood [texte imprimé] / William E. COPELAND, Auteur ; Carol E. ADAIR, Auteur ; Paul SMETANIN, Auteur ; David STIFF, Auteur ; Carla BRIANTE, Auteur ; Ian COLMAN, Auteur ; David M. FERGUSSON, Auteur ; John HORWOOD, Auteur ; Richie POULTON, Auteur ; E. Jane COSTELLO, Auteur ; Adrian ANGOLD, Auteur . - p.791-799. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.791-799 Mots-clés : Epidemiology  longitudinal  depression  anxiety  behavioral disorders  comorbidity Index. décimale : PER Périodiques Résumé : Background Quantifying diagnostic transitions across development is needed to estimate the long-term burden of mental illness. This study estimated patterns of diagnostic transitions from childhood to adolescence and from adolescence to early adulthood. Methods Patterns of diagnostic transitions were estimated using data from three prospective, longitudinal studies involving close to 20,000 observations of 3,722 participants followed across multiple developmental periods covering ages 9–30. Common DSM psychiatric disorders were assessed in childhood (ages 9–12; two samples), adolescence (ages 13–18; three samples), and early adulthood (ages 19 to age 32; three samples) with structured psychiatric interviews and questionnaires. Results Having a disorder at an early period was associated with at least a threefold increase in odds for having a disorder at a later period. Homotypic and heterotypic transitions were observed for every disorder category. The strongest evidence of continuity was seen for behavioral disorders (particularly ADHD) with less evidence for emotional disorders such as depression and anxiety. Limited evidence was found in adjusted models for behavioral disorders predicting later emotional disorders. Adult substance disorders were preceded by behavioral disorders, but not anxiety or depression. Conclusions Having a disorder in childhood or adolescence is a potent risk factor for a range of psychiatric problems later in development. These findings provide further support for prevention and early life intervention efforts and suggest that treatment at younger ages, while justified in its own right, may also have potential to reduce the risk for disorders later in development. En ligne : http://dx.doi.org/10.1111/jcpp.12062 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=203

Early adversities accelerate epigenetic aging into adulthood: a 10-year, within-subject analysis / William E. COPELAND in Journal of Child Psychology and Psychiatry, 63-11 (November 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1308-1315 Titre : Early adversities accelerate epigenetic aging into adulthood: a 10-year, within-subject analysis Type de document : texte imprimé Auteurs : William E. COPELAND, Auteur ; Lilly SHANAHAN, Auteur ; Ellen W. MCGINNIS, Auteur ; Karolina A. ABERG, Auteur ; Edwin J. C. G. VAN DEN OORD, Auteur Article en page(s) : p.1308-1315 Langues : Anglais (eng) Mots-clés : Adolescent  Humans  Child  Young Adult  Adult  Cross-Sectional Studies  Risk Factors  Anxiety Disorders  Aging/genetics  Epigenesis, Genetic  Childhood  DNA methylation  adversity  aging  epigenetic  longitudinal Index. décimale : PER Périodiques Résumé : BACKGROUND: Longitudinal studies are needed to clarify whether early adversities are associated with advanced methylation age or if they actually accelerate methylation aging. This study test whether different dimensions of childhood adversity accelerate biological aging from childhood to adulthood, and, if so, via which mechanisms. METHODS: 381 participants provided one blood sample in childhood (average age 15.0; SD=2.3) and another in young adulthood (average age 23.1; SD=2.8). Participants and their parents provided a median of 6 childhood assessments (total=1,950 childhood observations), reporting exposures to different types of adversity dimensions (i.e. threat, material deprivation, loss, unpredictability). The blood samples were assayed to estimate DNA methylation age in both childhood and adulthood and also change in methylation age across this period. RESULTS: Cross-sectional associations between the childhood adversity dimensions and childhood measures of methylation age were non-significant. In contrast, multiple adversity dimensions were associated with accelerated within-person change in methylation age from adolescence to young adulthood. These associations attenuated in model testing all dimensions at the same time. Accelerated aging increased with increasing number of childhood adversities: Individuals with highest number of adversities experienced 2+ additional years of methylation aging compared to those with no exposure to childhood adversities. The association between total childhood adversity exposure and accelerated aging was partially explained by childhood depressive symptoms, but not anxiety or behavioral symptoms. CONCLUSIONS: Early adversities accelerate epigenetic aging long after they occur, in proportion to the total number of such experiences, and in a manner consistent with a shared effect that crosses multiple early dimensions of risk. En ligne : http://dx.doi.org/10.1111/jcpp.13575 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 [article] Early adversities accelerate epigenetic aging into adulthood: a 10-year, within-subject analysis [texte imprimé] / William E. COPELAND, Auteur ; Lilly SHANAHAN, Auteur ; Ellen W. MCGINNIS, Auteur ; Karolina A. ABERG, Auteur ; Edwin J. C. G. VAN DEN OORD, Auteur . - p.1308-1315. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1308-1315 Mots-clés : Adolescent  Humans  Child  Young Adult  Adult  Cross-Sectional Studies  Risk Factors  Anxiety Disorders  Aging/genetics  Epigenesis, Genetic  Childhood  DNA methylation  adversity  aging  epigenetic  longitudinal Index. décimale : PER Périodiques Résumé : BACKGROUND: Longitudinal studies are needed to clarify whether early adversities are associated with advanced methylation age or if they actually accelerate methylation aging. This study test whether different dimensions of childhood adversity accelerate biological aging from childhood to adulthood, and, if so, via which mechanisms. METHODS: 381 participants provided one blood sample in childhood (average age 15.0; SD=2.3) and another in young adulthood (average age 23.1; SD=2.8). Participants and their parents provided a median of 6 childhood assessments (total=1,950 childhood observations), reporting exposures to different types of adversity dimensions (i.e. threat, material deprivation, loss, unpredictability). The blood samples were assayed to estimate DNA methylation age in both childhood and adulthood and also change in methylation age across this period. RESULTS: Cross-sectional associations between the childhood adversity dimensions and childhood measures of methylation age were non-significant. In contrast, multiple adversity dimensions were associated with accelerated within-person change in methylation age from adolescence to young adulthood. These associations attenuated in model testing all dimensions at the same time. Accelerated aging increased with increasing number of childhood adversities: Individuals with highest number of adversities experienced 2+ additional years of methylation aging compared to those with no exposure to childhood adversities. The association between total childhood adversity exposure and accelerated aging was partially explained by childhood depressive symptoms, but not anxiety or behavioral symptoms. CONCLUSIONS: Early adversities accelerate epigenetic aging long after they occur, in proportion to the total number of such experiences, and in a manner consistent with a shared effect that crosses multiple early dimensions of risk. En ligne : http://dx.doi.org/10.1111/jcpp.13575 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490

Impact of dimensions of early adversity on adult health and functioning: A 2-decade, longitudinal study / Ellen W. MCGINNIS in Development and Psychopathology, 34-2 (May 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-2 (May 2022) . - 527-538 Titre : Impact of dimensions of early adversity on adult health and functioning: A 2-decade, longitudinal study Type de document : texte imprimé Auteurs : Ellen W. MCGINNIS, Auteur ; Margaret SHERIDAN, Auteur ; William E. COPELAND, Auteur Article en page(s) : 527-538 Langues : Anglais (eng) Mots-clés : child adversity  deprivation  life history  longitudinal  threat Index. décimale : PER Périodiques Résumé : Recent neurodevelopmental and evolutionary theories offer strong theoretical rationales and some empirical evidence to support the importance of specific dimensions of early adversity. However, studies have often been limited by omission of other adversity dimensions, singular outcomes, and short follow up durations. 1,420 participants in the community, Great Smoky Mountains Study, were assessed up to eight times between age 9 and 16 for four dimensions of early adversity: Threat, Material Deprivation, Unpredictability, and Loss (as well as a Cumulative Adversity measure). Participants were followed up to four times in adulthood (ages 19, 21, 25, and 30) to measure psychiatric disorders, substance disorder, and ?real-world? functioning. Every childhood adversity dimension was associated with multiple adult psychiatric, substance, or functional outcomes when tested simultaneously in a multivariable analysis that accounted for other childhood adversities. There was evidence of differential impact of dimensions of adversity exposure on proximal outcomes (e.g., material deprivation and IQ) and even on distal outcomes (e.g., threat and emotional functioning). There were similar levels of prediction between the best set of individual adversity scales and a single cumulative adversity measure when considering distal outcomes. All dimensions of childhood adversity have lasting, pleiotropic effects, on adult health and functioning, but these dimensions may act via distinct proximal pathways. En ligne : http://dx.doi.org/10.1017/s095457942100167x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Impact of dimensions of early adversity on adult health and functioning: A 2-decade, longitudinal study [texte imprimé] / Ellen W. MCGINNIS, Auteur ; Margaret SHERIDAN, Auteur ; William E. COPELAND, Auteur . - 527-538. Langues : Anglais (eng) in Development and Psychopathology > 34-2 (May 2022) . - 527-538 Mots-clés : child adversity  deprivation  life history  longitudinal  threat Index. décimale : PER Périodiques Résumé : Recent neurodevelopmental and evolutionary theories offer strong theoretical rationales and some empirical evidence to support the importance of specific dimensions of early adversity. However, studies have often been limited by omission of other adversity dimensions, singular outcomes, and short follow up durations. 1,420 participants in the community, Great Smoky Mountains Study, were assessed up to eight times between age 9 and 16 for four dimensions of early adversity: Threat, Material Deprivation, Unpredictability, and Loss (as well as a Cumulative Adversity measure). Participants were followed up to four times in adulthood (ages 19, 21, 25, and 30) to measure psychiatric disorders, substance disorder, and ?real-world? functioning. Every childhood adversity dimension was associated with multiple adult psychiatric, substance, or functional outcomes when tested simultaneously in a multivariable analysis that accounted for other childhood adversities. There was evidence of differential impact of dimensions of adversity exposure on proximal outcomes (e.g., material deprivation and IQ) and even on distal outcomes (e.g., threat and emotional functioning). There were similar levels of prediction between the best set of individual adversity scales and a single cumulative adversity measure when considering distal outcomes. All dimensions of childhood adversity have lasting, pleiotropic effects, on adult health and functioning, but these dimensions may act via distinct proximal pathways. En ligne : http://dx.doi.org/10.1017/s095457942100167x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

Intergenerational effects of the Fast Track intervention on the home environment: A randomized control trial / William Andrew ROTHENBERG in Journal of Child Psychology and Psychiatry, 64-5 (May 2023)  

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Longitudinal dimensionality of adolescent psychopathology: testing the differentiation hypothesis / Sonya K. STERBA in Journal of Child Psychology and Psychiatry, 51-8 (August 2010)  

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A methylation study implicates the rewiring of brain neural circuits during puberty in the emergence of sex differences in depression symptoms / Robin F. CHAN in Journal of Child Psychology and Psychiatry, 63-7 (July 2022)  

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Pathways to health: A longitudinal examination of protective factors in children with and without preschool anxiety / Esmeralda NAVARRO in Development and Psychopathology, 37-3 (August 2025)  

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Pubertal timing moderates the same-day coupling between family hassles and negative affect in girls and boys / Michael A. RUSSELL ; Candice L. ODGERS ; Rick H. HOYLE ; William E. COPELAND in Development and Psychopathology, 35-4 (October 2023)  

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Specificity of putative psychosocial risk factors for psychiatric disorders in children and adolescents / Lilly SHANAHAN in Journal of Child Psychology and Psychiatry, 49-1 (January 2008)  

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Thresholds and accuracy in screening tools for early detection of psychopathology / R. Christopher SHELDRICK in Journal of Child Psychology and Psychiatry, 56-9 (September 2015)  

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Trends in psychopathology across the adolescent years: What changes when children become adolescents, and when adolescents become adults? / E. Jane COSTELLO in Journal of Child Psychology and Psychiatry, 52-10 (October 2011)  

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