Early Life Antibiotic Exposure and the Subsequent Risk of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis / Hai-Ying YU in Journal of Autism and Developmental Disorders, 52-5 (May 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-5 (May 2022) . - p.2236-2246 Titre : Early Life Antibiotic Exposure and the Subsequent Risk of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis Type de document : Texte imprimé et/ou numérique Auteurs : Hai-Ying YU, Auteur ; Yuan-Yue ZHOU, Auteur ; Li-Ya PAN, Auteur ; Xue ZHANG, Auteur ; Hai-Yin JIANG, Auteur Article en page(s) : p.2236-2246 Langues : Anglais (eng) Mots-clés : Anti-Bacterial Agents/adverse effects  Attention Deficit Disorder with Hyperactivity/epidemiology  Autism Spectrum Disorder/complications/etiology  Humans  Siblings  Infection  Neurodevelopment  Risk  Systematic Index. décimale : PER Périodiques Résumé : This study was conducted to assess this association between early life antibiotic exposure and the risk of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) in later life. The results showed that early life antibiotic exposure was associated with an increased risk of ASD (OR=1.13, 95% confidence interval (CI): 1.07-1.21) or ADHD (OR=1.18, 95% CI: 1.1-1.27). However, this association for ASD (OR=1.04, 95% CI: 0.97-1.11) or ADHD (OR=0.98, 95% CI: 0.94-1.02) disappeared when data from sibling-matched studies were pooled. The statistically significant association between early life antibiotic exposure and ASD or ADHD in later life can be partially explained by unmeasured genetic and familial confounding factors. En ligne : http://dx.doi.org/10.1007/s10803-021-05121-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476 [article] Early Life Antibiotic Exposure and the Subsequent Risk of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis [Texte imprimé et/ou numérique] / Hai-Ying YU, Auteur ; Yuan-Yue ZHOU, Auteur ; Li-Ya PAN, Auteur ; Xue ZHANG, Auteur ; Hai-Yin JIANG, Auteur . - p.2236-2246. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-5 (May 2022) . - p.2236-2246 Mots-clés : Anti-Bacterial Agents/adverse effects  Attention Deficit Disorder with Hyperactivity/epidemiology  Autism Spectrum Disorder/complications/etiology  Humans  Siblings  Infection  Neurodevelopment  Risk  Systematic Index. décimale : PER Périodiques Résumé : This study was conducted to assess this association between early life antibiotic exposure and the risk of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) in later life. The results showed that early life antibiotic exposure was associated with an increased risk of ASD (OR=1.13, 95% confidence interval (CI): 1.07-1.21) or ADHD (OR=1.18, 95% CI: 1.1-1.27). However, this association for ASD (OR=1.04, 95% CI: 0.97-1.11) or ADHD (OR=0.98, 95% CI: 0.94-1.02) disappeared when data from sibling-matched studies were pooled. The statistically significant association between early life antibiotic exposure and ASD or ADHD in later life can be partially explained by unmeasured genetic and familial confounding factors. En ligne : http://dx.doi.org/10.1007/s10803-021-05121-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476

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