Eye Movement Desensitization and Reprocessing (EMDR) Therapy as a Feasible and Potential Effective Treatment for Adults with Autism Spectrum Disorder (ASD) and a History of Adverse Events / Ella LOBREGT-VAN BUUREN in Journal of Autism and Developmental Disorders, 49-1 (January 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.151-164 Titre : Eye Movement Desensitization and Reprocessing (EMDR) Therapy as a Feasible and Potential Effective Treatment for Adults with Autism Spectrum Disorder (ASD) and a History of Adverse Events Type de document : texte imprimé Auteurs : Ella LOBREGT-VAN BUUREN, Auteur ; Bram SIZOO, Auteur ; Liesbeth MEVISSEN, Auteur ; Ad DE JONGH, Auteur Article en page(s) : p.151-164 Langues : Anglais (eng) Mots-clés : Asd  Autism spectrum disorder  Diagnostic overshadowing  Emdr  Ptsd  Trauma Index. décimale : PER Périodiques Résumé : The study investigated whether EMDR is a feasible therapy for adults with ASD and a history of adverse events, and whether it is associated with reductions in symptoms of PTSD, psychological distress and autism. Participants received 6 to 8 weeks treatment as usual (TAU), followed by a maximum of 8 sessions EMDR added to TAU, and a follow-up of 6-8 weeks with TAU only. Results showed a significant reduction of symptoms of post-traumatic stress (IES-R: d = 1.16), psychological distress (BSI: d = 0.93) and autistic features (SRS-A: d = 0.39). Positive results were maintained at follow-up. The results suggest EMDR therapy to be a feasible and potentially effective treatment for individuals with ASD who suffer from the consequences of exposure to distressing events. En ligne : http://dx.doi.org/10.1007/s10803-018-3687-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376 [article] Eye Movement Desensitization and Reprocessing (EMDR) Therapy as a Feasible and Potential Effective Treatment for Adults with Autism Spectrum Disorder (ASD) and a History of Adverse Events [texte imprimé] / Ella LOBREGT-VAN BUUREN, Auteur ; Bram SIZOO, Auteur ; Liesbeth MEVISSEN, Auteur ; Ad DE JONGH, Auteur . - p.151-164. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.151-164 Mots-clés : Asd  Autism spectrum disorder  Diagnostic overshadowing  Emdr  Ptsd  Trauma Index. décimale : PER Périodiques Résumé : The study investigated whether EMDR is a feasible therapy for adults with ASD and a history of adverse events, and whether it is associated with reductions in symptoms of PTSD, psychological distress and autism. Participants received 6 to 8 weeks treatment as usual (TAU), followed by a maximum of 8 sessions EMDR added to TAU, and a follow-up of 6-8 weeks with TAU only. Results showed a significant reduction of symptoms of post-traumatic stress (IES-R: d = 1.16), psychological distress (BSI: d = 0.93) and autistic features (SRS-A: d = 0.39). Positive results were maintained at follow-up. The results suggest EMDR therapy to be a feasible and potentially effective treatment for individuals with ASD who suffer from the consequences of exposure to distressing events. En ligne : http://dx.doi.org/10.1007/s10803-018-3687-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376

Predictive validity of self-report questionnaires in the assessment of autism spectrum disorders in adults / Bram B. SIZOO in Autism, 19-7 (October 2015)  

Public ISBD [article]  inAutism > 19-7 (October 2015) . - p.842-849 Titre : Predictive validity of self-report questionnaires in the assessment of autism spectrum disorders in adults Type de document : texte imprimé Auteurs : Bram B. SIZOO, Auteur ; E.H. HORWITZ, Auteur ; Jan-Pieter TEUNISSE, Auteur ; Cornelis C. KAN, Auteur ; Constance T.W.M. VISSERS, Auteur ; E.J.M. FORCEVILLE, Auteur ; A.J.P. VAN VOORST, Auteur ; Hilde M. GEURTS, Auteur Année de publication : 2015 Article en page(s) : p.842-849 Langues : Anglais (eng) Mots-clés : autism  Autism-Spectrum Quotient  casefinding  RAADS-R-NL  self-report questionnaires Index. décimale : PER Périodiques Résumé : While various screening instruments for autism spectrum disorders are widely used in diagnostic assessments, their psychometric properties have not been simultaneously evaluated in the outpatient setting where these instruments are used most. In this study, we tested the Ritvo Autism Asperger Diagnostic Scale–Revised and two short versions of the Autism-Spectrum Quotient, the AQ-28 and AQ-10, in 210 patients referred for autism spectrum disorder assessment and in 63 controls. Of the 210 patients, 139 received an autism spectrum disorder diagnosis and 71 received another psychiatric diagnosis. The positive predictive values indicate that these tests correctly identified autism spectrum disorder patients in almost 80% of the referred cases. However, the negative predictive values suggest that only half of the referred patients without autism spectrum disorder were correctly identified. The sensitivity and specificity of each of these instruments were much lower than the values reported in the literature. In this study, the sensitivity of the Ritvo Autism Asperger Diagnostic Scale–Revised was the highest (73%), and the Autism-Spectrum Quotient short forms had the highest specificity (70% and 72%). Based on the similar area under the curve values, there is no clear preference for any of the three instruments. None of these instruments have sufficient validity to reliably predict a diagnosis of autism spectrum disorder in outpatient settings. En ligne : http://dx.doi.org/10.1177/1362361315589869 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=269 [article] Predictive validity of self-report questionnaires in the assessment of autism spectrum disorders in adults [texte imprimé] / Bram B. SIZOO, Auteur ; E.H. HORWITZ, Auteur ; Jan-Pieter TEUNISSE, Auteur ; Cornelis C. KAN, Auteur ; Constance T.W.M. VISSERS, Auteur ; E.J.M. FORCEVILLE, Auteur ; A.J.P. VAN VOORST, Auteur ; Hilde M. GEURTS, Auteur . - 2015 . - p.842-849. Langues : Anglais (eng) in Autism > 19-7 (October 2015) . - p.842-849 Mots-clés : autism  Autism-Spectrum Quotient  casefinding  RAADS-R-NL  self-report questionnaires Index. décimale : PER Périodiques Résumé : While various screening instruments for autism spectrum disorders are widely used in diagnostic assessments, their psychometric properties have not been simultaneously evaluated in the outpatient setting where these instruments are used most. In this study, we tested the Ritvo Autism Asperger Diagnostic Scale–Revised and two short versions of the Autism-Spectrum Quotient, the AQ-28 and AQ-10, in 210 patients referred for autism spectrum disorder assessment and in 63 controls. Of the 210 patients, 139 received an autism spectrum disorder diagnosis and 71 received another psychiatric diagnosis. The positive predictive values indicate that these tests correctly identified autism spectrum disorder patients in almost 80% of the referred cases. However, the negative predictive values suggest that only half of the referred patients without autism spectrum disorder were correctly identified. The sensitivity and specificity of each of these instruments were much lower than the values reported in the literature. In this study, the sensitivity of the Ritvo Autism Asperger Diagnostic Scale–Revised was the highest (73%), and the Autism-Spectrum Quotient short forms had the highest specificity (70% and 72%). Based on the similar area under the curve values, there is no clear preference for any of the three instruments. None of these instruments have sufficient validity to reliably predict a diagnosis of autism spectrum disorder in outpatient settings. En ligne : http://dx.doi.org/10.1177/1362361315589869 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=269

Secondary effects of dialectical behaviour therapy on social functioning, quality of life, and autism traits in autistic adults with suicidality / Anne HUNTJENS in Autism, 29-5 (May 2025)  

Public ISBD [article]  inAutism > 29-5 (May 2025) . - p.1333-1345 Titre : Secondary effects of dialectical behaviour therapy on social functioning, quality of life, and autism traits in autistic adults with suicidality Type de document : texte imprimé Auteurs : Anne HUNTJENS, Auteur ; LMC VAN DEN BOSCH, Auteur ; Bram SIZOO, Auteur ; Ad KERKHOF, Auteur ; Filip SMIT, Auteur ; Mark VAN DER GAAG, Auteur Article en page(s) : p.1333-1345 Langues : Anglais (eng) Mots-clés : autism  autism traits  dialectical behaviour therapy  quality of life  social functioning  suicidal behaviour Index. décimale : PER Périodiques Résumé : The effect of psychological treatment on social functioning, quality of life and autism traits in autistic people with suicidal behaviour remains largely unknown. At six Dutch mental health centres, 123 adult outpatients with Diagnostic and Statistical Manual of Mental Disorders (5th edition) diagnosed autism spectrum condition and suicidal behaviours were randomly assigned to dialectical behaviour therapy (n = 63) or treatment as usual (n = 60) to address their suicidal behaviours. This article analysed secondary outcomes on social functioning, quality of life and autism traits. Outcomes were compared at baseline, post-treatment at 6 months, and 12-month follow-up. At post-treatment, both social functioning (p < 0.001) and quality of life (p = 0.002) were significantly improved in the treatment condition compared to the control condition and remained so at 12-month follow-up (p = 0.003; p = 0.002). Autism traits did not differ between conditions. Autistic individuals with suicidal behaviours benefit modestly from treatment with dialectical behaviour therapy in social functioning and quality of life.Lay abstract Dialectical behaviour therapy is a comprehensive treatment that helps individuals improve distress tolerance, mindfulness, interpersonal effectiveness and emotion regulation. It is commonly used to assist those experiencing self-harm and suicidal thoughts or behaviours. Despite its broad application, our understanding of how dialectical behaviour therapy impacts autistic individuals with suicidal behaviour remains limited. This study compared dialectical behaviour therapy with treatment as usual in 123 autistic adults experiencing suicidal behaviours. Participants were recruited from six mental health centres, with 63 receiving dialectical behaviour therapy and 60 receiving treatment as usual. The study assessed outcomes such as social functioning, quality of life and specific autism traits over 12 months. Findings revealed that dialectical behaviour therapy led to significant improvements in social functioning and quality of life compared to treatment as usual, though there were no effects on autism traits. These improvements suggest that dialectical behaviour therapy holds promise as an effective treatment for autistic individuals grappling with suicidal behaviour. The findings strongly support the broader implementation of dialectical behaviour therapy in mental health centres, especially given the limited treatment options available for autistic individuals with suicidal tendencies. En ligne : https://dx.doi.org/10.1177/13623613241302875 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=555 [article] Secondary effects of dialectical behaviour therapy on social functioning, quality of life, and autism traits in autistic adults with suicidality [texte imprimé] / Anne HUNTJENS, Auteur ; LMC VAN DEN BOSCH, Auteur ; Bram SIZOO, Auteur ; Ad KERKHOF, Auteur ; Filip SMIT, Auteur ; Mark VAN DER GAAG, Auteur . - p.1333-1345. Langues : Anglais (eng) in Autism > 29-5 (May 2025) . - p.1333-1345 Mots-clés : autism  autism traits  dialectical behaviour therapy  quality of life  social functioning  suicidal behaviour Index. décimale : PER Périodiques Résumé : The effect of psychological treatment on social functioning, quality of life and autism traits in autistic people with suicidal behaviour remains largely unknown. At six Dutch mental health centres, 123 adult outpatients with Diagnostic and Statistical Manual of Mental Disorders (5th edition) diagnosed autism spectrum condition and suicidal behaviours were randomly assigned to dialectical behaviour therapy (n = 63) or treatment as usual (n = 60) to address their suicidal behaviours. This article analysed secondary outcomes on social functioning, quality of life and autism traits. Outcomes were compared at baseline, post-treatment at 6 months, and 12-month follow-up. At post-treatment, both social functioning (p < 0.001) and quality of life (p = 0.002) were significantly improved in the treatment condition compared to the control condition and remained so at 12-month follow-up (p = 0.003; p = 0.002). Autism traits did not differ between conditions. Autistic individuals with suicidal behaviours benefit modestly from treatment with dialectical behaviour therapy in social functioning and quality of life.Lay abstract Dialectical behaviour therapy is a comprehensive treatment that helps individuals improve distress tolerance, mindfulness, interpersonal effectiveness and emotion regulation. It is commonly used to assist those experiencing self-harm and suicidal thoughts or behaviours. Despite its broad application, our understanding of how dialectical behaviour therapy impacts autistic individuals with suicidal behaviour remains limited. This study compared dialectical behaviour therapy with treatment as usual in 123 autistic adults experiencing suicidal behaviours. Participants were recruited from six mental health centres, with 63 receiving dialectical behaviour therapy and 60 receiving treatment as usual. The study assessed outcomes such as social functioning, quality of life and specific autism traits over 12 months. Findings revealed that dialectical behaviour therapy led to significant improvements in social functioning and quality of life compared to treatment as usual, though there were no effects on autism traits. These improvements suggest that dialectical behaviour therapy holds promise as an effective treatment for autistic individuals grappling with suicidal behaviour. The findings strongly support the broader implementation of dialectical behaviour therapy in mental health centres, especially given the limited treatment options available for autistic individuals with suicidal tendencies. En ligne : https://dx.doi.org/10.1177/13623613241302875 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=555

Self-reported Suicidality in Male and Female Adults with Autism Spectrum Disorders: Rumination and Self-esteem / Titia G. ARWERT in Journal of Autism and Developmental Disorders, 50-10 (October 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-10 (October 2020) . - p.3598-3605 Titre : Self-reported Suicidality in Male and Female Adults with Autism Spectrum Disorders: Rumination and Self-esteem Type de document : texte imprimé Auteurs : Titia G. ARWERT, Auteur ; Bram B. SIZOO, Auteur Article en page(s) : p.3598-3605 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Gender  Rumination  Self-esteem  Self-report  Suicidality Index. décimale : PER Périodiques Résumé : Rumination and low self-esteem are associated with suicidality, and with autism spectrum disorders (ASD). However, rumination and self-esteem in relation to suicidality in adults with ASD have not been examined. This cross-sectional study (n = 75; 46 males and 29 females) investigates the relation of rumination and self-esteem to the absence/presence of suicidal ideation (SUIC+/-), history of attempted suicide (HAS), and severity of suicidality. Multivariate analysis of variance showed that self-esteem was significantly associated with SUIC+/-, whereas rumination was significantly associated with HAS. Multiple regression analysis showed that rumination and self-esteem were independently associated with severity of suicidality, but these lose their significant contribution, when statistically controlling for depression. The prevalence of suicidal ideation was 66.6%; gender was not a significant factor. En ligne : http://dx.doi.org/10.1007/s10803-020-04372-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432 [article] Self-reported Suicidality in Male and Female Adults with Autism Spectrum Disorders: Rumination and Self-esteem [texte imprimé] / Titia G. ARWERT, Auteur ; Bram B. SIZOO, Auteur . - p.3598-3605. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-10 (October 2020) . - p.3598-3605 Mots-clés : Autism spectrum disorder  Gender  Rumination  Self-esteem  Self-report  Suicidality Index. décimale : PER Périodiques Résumé : Rumination and low self-esteem are associated with suicidality, and with autism spectrum disorders (ASD). However, rumination and self-esteem in relation to suicidality in adults with ASD have not been examined. This cross-sectional study (n = 75; 46 males and 29 females) investigates the relation of rumination and self-esteem to the absence/presence of suicidal ideation (SUIC+/-), history of attempted suicide (HAS), and severity of suicidality. Multivariate analysis of variance showed that self-esteem was significantly associated with SUIC+/-, whereas rumination was significantly associated with HAS. Multiple regression analysis showed that rumination and self-esteem were independently associated with severity of suicidality, but these lose their significant contribution, when statistically controlling for depression. The prevalence of suicidal ideation was 66.6%; gender was not a significant factor. En ligne : http://dx.doi.org/10.1007/s10803-020-04372-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432

Temperament and character as endophenotype in adults with autism spectrum disorders or attention deficit/hyperactivity disorder / Bram B. SIZOO in Autism, 19-4 (May 2015)  

Public ISBD [article]  inAutism > 19-4 (May 2015) . - p.400-408 Titre : Temperament and character as endophenotype in adults with autism spectrum disorders or attention deficit/hyperactivity disorder Type de document : texte imprimé Auteurs : Bram B. SIZOO, Auteur ; Rutger Jan VAN DER GAAG, Auteur ; Wim VAN DEN BRINK, Auteur Article en page(s) : p.400-408 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum disorder and attention deficit/hyperactivity disorder overlap in several ways, raising questions about the nature of this comorbidity. Rommelse et al. published an innovative review of candidate endophenotypes for autism spectrum disorder and attention deficit/hyperactivity disorder in cognitive and brain domains. They found that all the endophenotypic impairments that were reviewed in attention deficit/hyperactivity disorder were also present in autism spectrum disorder, suggesting a continuity model with attention deficit/hyperactivity disorder as “a light form of autism spectrum disorder.” Using existing data, 75 adults with autism spectrum disorder and 53 with attention deficit/hyperactivity disorder were directly compared on autistic symptoms with the autism spectrum quotient, and on the endophenotypic measure of temperament and character, using the Abbreviated (Dutch: Verkorte) Temperament and Character Inventory. Based on the hypothesis that attention deficit/hyperactivity disorder and autism spectrum disorder are disorders on a continuous spectrum, autism spectrum quotient scores and abbreviated Temperament and Character Inventory scores were expected to be different from normal controls in both disorders in a similar direction. In addition, the autism spectrum quotient and abbreviated Temperament and Character Inventory scores were expected to be closely correlated. These conditions applied to only two of the seven Abbreviated Temperament and Character Inventory scales (harm avoidance and self-directedness), suggesting that temperament and character as an endophenotype of autism spectrum disorder and attention deficit/hyperactivity disorder provides only partial support for the continuity hypothesis of autism spectrum disorder and attention deficit/hyperactivity disorder. En ligne : http://dx.doi.org/10.1177/1362361314522352 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=257 [article] Temperament and character as endophenotype in adults with autism spectrum disorders or attention deficit/hyperactivity disorder [texte imprimé] / Bram B. SIZOO, Auteur ; Rutger Jan VAN DER GAAG, Auteur ; Wim VAN DEN BRINK, Auteur . - p.400-408. Langues : Anglais (eng) in Autism > 19-4 (May 2015) . - p.400-408 Index. décimale : PER Périodiques Résumé : Autism spectrum disorder and attention deficit/hyperactivity disorder overlap in several ways, raising questions about the nature of this comorbidity. Rommelse et al. published an innovative review of candidate endophenotypes for autism spectrum disorder and attention deficit/hyperactivity disorder in cognitive and brain domains. They found that all the endophenotypic impairments that were reviewed in attention deficit/hyperactivity disorder were also present in autism spectrum disorder, suggesting a continuity model with attention deficit/hyperactivity disorder as “a light form of autism spectrum disorder.” Using existing data, 75 adults with autism spectrum disorder and 53 with attention deficit/hyperactivity disorder were directly compared on autistic symptoms with the autism spectrum quotient, and on the endophenotypic measure of temperament and character, using the Abbreviated (Dutch: Verkorte) Temperament and Character Inventory. Based on the hypothesis that attention deficit/hyperactivity disorder and autism spectrum disorder are disorders on a continuous spectrum, autism spectrum quotient scores and abbreviated Temperament and Character Inventory scores were expected to be different from normal controls in both disorders in a similar direction. In addition, the autism spectrum quotient and abbreviated Temperament and Character Inventory scores were expected to be closely correlated. These conditions applied to only two of the seven Abbreviated Temperament and Character Inventory scales (harm avoidance and self-directedness), suggesting that temperament and character as an endophenotype of autism spectrum disorder and attention deficit/hyperactivity disorder provides only partial support for the continuity hypothesis of autism spectrum disorder and attention deficit/hyperactivity disorder. En ligne : http://dx.doi.org/10.1177/1362361314522352 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=257

Temperament and character as risk factor for suicide ideation and attempts in adults with autism spectrum disorders / Annelie A.T. HOOIJER in Autism Research, 13-1 (January 2020)  

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Using the Autism-Spectrum Quotient to Discriminate Autism Spectrum Disorder from ADHD in Adult Patients With and Without Comorbid Substance Use Disorder / Bram B. SIZOO in Journal of Autism and Developmental Disorders, 39-9 (September 2009)  

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