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Auteur Irma MOILANEN |
Documents disponibles écrits par cet auteur (24)
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Pragmatic inference abilities in individuals with Asperger syndrome or high-functioning autism. A review / Soile LOUKUSA in Research in Autism Spectrum Disorders, 3-4 (October-December 2009)
[article]
Titre : Pragmatic inference abilities in individuals with Asperger syndrome or high-functioning autism. A review Type de document : Texte imprimé et/ou numérique Auteurs : Soile LOUKUSA, Auteur ; Irma MOILANEN, Auteur Année de publication : 2009 Article en page(s) : p.890-904 Langues : Anglais (eng) Mots-clés : Pragmatics Inference Comprehension Context High-functioning-autism Asperger-syndrome Index. décimale : PER Périodiques Résumé : This review summarizes studies involving pragmatic language comprehension and inference abilities in individuals with Asperger syndrome or high-functioning autism. Systematic searches of three electronic databases, selected journals, and reference lists identified 20 studies meeting the inclusion criteria. These studies were evaluated in terms of: (a) purpose of study, (b) participant characteristics and (c) procedures. Across the studies, the ages of participants varied between 6 and 57 years. The pragmatic comprehension and inference abilities measured varied from homograph comprehension to ability to understand non-literal statements. Pragmatic inference weaknesses, but not inabilities, were found throughout the studies. However, researchers did not wholly agree on the reasons and the extent of processing difficulties. The most commonly suggested explanations for pragmatic inference deficits were theory of mind and central coherence. En ligne : http://dx.doi.org/10.1016/j.rasd.2009.05.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=816
in Research in Autism Spectrum Disorders > 3-4 (October-December 2009) . - p.890-904[article] Pragmatic inference abilities in individuals with Asperger syndrome or high-functioning autism. A review [Texte imprimé et/ou numérique] / Soile LOUKUSA, Auteur ; Irma MOILANEN, Auteur . - 2009 . - p.890-904.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 3-4 (October-December 2009) . - p.890-904
Mots-clés : Pragmatics Inference Comprehension Context High-functioning-autism Asperger-syndrome Index. décimale : PER Périodiques Résumé : This review summarizes studies involving pragmatic language comprehension and inference abilities in individuals with Asperger syndrome or high-functioning autism. Systematic searches of three electronic databases, selected journals, and reference lists identified 20 studies meeting the inclusion criteria. These studies were evaluated in terms of: (a) purpose of study, (b) participant characteristics and (c) procedures. Across the studies, the ages of participants varied between 6 and 57 years. The pragmatic comprehension and inference abilities measured varied from homograph comprehension to ability to understand non-literal statements. Pragmatic inference weaknesses, but not inabilities, were found throughout the studies. However, researchers did not wholly agree on the reasons and the extent of processing difficulties. The most commonly suggested explanations for pragmatic inference deficits were theory of mind and central coherence. En ligne : http://dx.doi.org/10.1016/j.rasd.2009.05.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=816 Processing of Affective Speech Prosody is Impaired in Asperger Syndrome / Pirjo KORPILAHTI in Journal of Autism and Developmental Disorders, 37-8 (September 2007)
[article]
Titre : Processing of Affective Speech Prosody is Impaired in Asperger Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Pirjo KORPILAHTI, Auteur ; Sanna KUUSIKKO, Auteur ; Marja-Leena MATTILA, Auteur ; Irma MOILANEN, Auteur ; Eira JANSSON-VERKASALO, Auteur ; Kalervo SUOMINEN, Auteur ; Seppo RYTKY, Auteur ; David L. PAULS, Auteur Année de publication : 2007 Article en page(s) : 1539-1549 Langues : Anglais (eng) Mots-clés : Asperger-syndrome Auditory-perception Affective-prosody Familial-pattern ERP Index. décimale : PER Périodiques Résumé : Many people with the diagnosis of Asperger syndrome (AS) show poorly developed skills in understanding emotional messages. The present study addressed discrimination of speech prosody in children with AS at neurophysiological level. Detection of affective prosody was investigated in one-word utterances as indexed by the N1 and the mismatch negativity (MMN) of auditory event-related potentials (ERPs). Data from fourteen boys with AS were compared with those for thirteen typically developed boys. These results suggest atypical neural responses to affective prosody in children with AS and their fathers, especially over the RH, and that this impairment can already be seen at low-level information processes. Our results provide evidence for familial patterns of abnormal auditory brain reactions to prosodic features of speech. En ligne : http://dx.doi.org/10.1007/s10803-006-0271-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=165
in Journal of Autism and Developmental Disorders > 37-8 (September 2007) . - 1539-1549[article] Processing of Affective Speech Prosody is Impaired in Asperger Syndrome [Texte imprimé et/ou numérique] / Pirjo KORPILAHTI, Auteur ; Sanna KUUSIKKO, Auteur ; Marja-Leena MATTILA, Auteur ; Irma MOILANEN, Auteur ; Eira JANSSON-VERKASALO, Auteur ; Kalervo SUOMINEN, Auteur ; Seppo RYTKY, Auteur ; David L. PAULS, Auteur . - 2007 . - 1539-1549.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 37-8 (September 2007) . - 1539-1549
Mots-clés : Asperger-syndrome Auditory-perception Affective-prosody Familial-pattern ERP Index. décimale : PER Périodiques Résumé : Many people with the diagnosis of Asperger syndrome (AS) show poorly developed skills in understanding emotional messages. The present study addressed discrimination of speech prosody in children with AS at neurophysiological level. Detection of affective prosody was investigated in one-word utterances as indexed by the N1 and the mismatch negativity (MMN) of auditory event-related potentials (ERPs). Data from fourteen boys with AS were compared with those for thirteen typically developed boys. These results suggest atypical neural responses to affective prosody in children with AS and their fathers, especially over the RH, and that this impairment can already be seen at low-level information processes. Our results provide evidence for familial patterns of abnormal auditory brain reactions to prosodic features of speech. En ligne : http://dx.doi.org/10.1007/s10803-006-0271-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=165 Reelin Associated With Restricted and Stereotyped Behavior Based on Principal Component Analysis on Autism Diagnostic Interview-Revised / Ulrika ROINE in Autism - Open Access, 3-1 (March 2013)
[article]
Titre : Reelin Associated With Restricted and Stereotyped Behavior Based on Principal Component Analysis on Autism Diagnostic Interview-Revised Type de document : Texte imprimé et/ou numérique Auteurs : Ulrika ROINE, Auteur ; Samuli RIPATTI, Auteur ; Karola REHNSTROM, Auteur ; Timo ROINE, Auteur ; Helena KILPINEN, Auteur ; Ida SURAKKA, Auteur ; Juho WEDENOJA, Auteur ; Tero YLISAUKKO-OJA, Auteur ; Elli KEMPAS, Auteur ; Jaana WESSMAN, Auteur ; Irma MOILANEN, Auteur ; Marja-Leena MATTILA, Auteur ; Marko KIELINEN, Auteur ; Katja JUSSILA, Auteur ; Saara SUOMALAINEN, Auteur ; Esko PULKKINEN, Auteur ; Lennart VON WENDT, Auteur ; Leena PELTONEN, Auteur Année de publication : 2013 Article en page(s) : 9 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background: Twin and family studies have indicated a strong genetic component in autism spectrum disorders, and genetic studies have revealed highly heterogeneous risk factors. The range and severity of the symptom presentation also vary in the spectrum. Thus, symptom-based phenotypes are putatively more closely related to the underlying biology of autism than the end-state diagnosis.
Methods: We performed principal component analysis on Autism Diagnostic Interview-Revised algorithm for 117 Finnish families and 594 families from the Autism Genetic Research Exchange (AGRE). The resulting continuous component scores were used as quantitative phenotypes in family-based association analysis. In addition, K-means clustering was performed to cluster and visualize the results of the PCA. Unaffected siblings were included in the study.
Results: The components were interpreted as Social Component (SC), communication component and Restricted and Stereotyped Behavior Component (RSBC). K-means clustering showed that, especially in SC, the range of the symptom severity was increased by the siblings. The association of neuroligin 1 with SC was increased, compared to a previous study where only the end-state diagnosis was used. In RSBC, the range of the symptom severity of siblings overlapped greatly with that of patients, which could explain why no association of reelin was found in previous studies in which only the end-state diagnosis was used, but a significant association of reelin with RSBC was now found in the Finnish families (Bonferroni-corrected p=0.029 for rs362644). Although, the Finnish sample is isolated and genetically very homogeneous, compared to the heterogeneous background of AGRE families, many single-nucleotide polymorphisms in reelin, showed modest association with RSBC in the AGRE sample, too.
Conclusions: This study demonstrates how the quantitative phenotypes can affect the association analyses, and yields further support to the use of siblings in the study of complex neuropsychiatric disorders.En ligne : http://dx.doi.org/10.4172/2165-7890.1000107 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=211
in Autism - Open Access > 3-1 (March 2013) . - 9 p.[article] Reelin Associated With Restricted and Stereotyped Behavior Based on Principal Component Analysis on Autism Diagnostic Interview-Revised [Texte imprimé et/ou numérique] / Ulrika ROINE, Auteur ; Samuli RIPATTI, Auteur ; Karola REHNSTROM, Auteur ; Timo ROINE, Auteur ; Helena KILPINEN, Auteur ; Ida SURAKKA, Auteur ; Juho WEDENOJA, Auteur ; Tero YLISAUKKO-OJA, Auteur ; Elli KEMPAS, Auteur ; Jaana WESSMAN, Auteur ; Irma MOILANEN, Auteur ; Marja-Leena MATTILA, Auteur ; Marko KIELINEN, Auteur ; Katja JUSSILA, Auteur ; Saara SUOMALAINEN, Auteur ; Esko PULKKINEN, Auteur ; Lennart VON WENDT, Auteur ; Leena PELTONEN, Auteur . - 2013 . - 9 p.
Langues : Anglais (eng)
in Autism - Open Access > 3-1 (March 2013) . - 9 p.
Index. décimale : PER Périodiques Résumé : Background: Twin and family studies have indicated a strong genetic component in autism spectrum disorders, and genetic studies have revealed highly heterogeneous risk factors. The range and severity of the symptom presentation also vary in the spectrum. Thus, symptom-based phenotypes are putatively more closely related to the underlying biology of autism than the end-state diagnosis.
Methods: We performed principal component analysis on Autism Diagnostic Interview-Revised algorithm for 117 Finnish families and 594 families from the Autism Genetic Research Exchange (AGRE). The resulting continuous component scores were used as quantitative phenotypes in family-based association analysis. In addition, K-means clustering was performed to cluster and visualize the results of the PCA. Unaffected siblings were included in the study.
Results: The components were interpreted as Social Component (SC), communication component and Restricted and Stereotyped Behavior Component (RSBC). K-means clustering showed that, especially in SC, the range of the symptom severity was increased by the siblings. The association of neuroligin 1 with SC was increased, compared to a previous study where only the end-state diagnosis was used. In RSBC, the range of the symptom severity of siblings overlapped greatly with that of patients, which could explain why no association of reelin was found in previous studies in which only the end-state diagnosis was used, but a significant association of reelin with RSBC was now found in the Finnish families (Bonferroni-corrected p=0.029 for rs362644). Although, the Finnish sample is isolated and genetically very homogeneous, compared to the heterogeneous background of AGRE families, many single-nucleotide polymorphisms in reelin, showed modest association with RSBC in the AGRE sample, too.
Conclusions: This study demonstrates how the quantitative phenotypes can affect the association analyses, and yields further support to the use of siblings in the study of complex neuropsychiatric disorders.En ligne : http://dx.doi.org/10.4172/2165-7890.1000107 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=211 Social Anxiety in High-functioning Children and Adolescents with Autism and Asperger Syndrome / Sanna KUUSIKKO in Journal of Autism and Developmental Disorders, 38-9 (October 2008)
[article]
Titre : Social Anxiety in High-functioning Children and Adolescents with Autism and Asperger Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Sanna KUUSIKKO, Auteur ; Alice S. CARTER, Auteur ; Katja JUSSILA, Auteur ; Marja-Leena MATTILA, Auteur ; Hanna EBELING, Auteur ; Irma MOILANEN, Auteur ; David L. PAULS, Auteur ; Rachel POLLOCK-WURMAN, Auteur Année de publication : 2008 Article en page(s) : p.1697-1709 Langues : Anglais (eng) Mots-clés : Asperger-syndrome High-functioning-autism Social-anxiety Social-phobia Index. décimale : PER Périodiques Résumé : We examined social anxiety and internalizing symptoms using the Social Phobia and Anxiety Inventory for Children (SPAI-C), the Social Anxiety Scale for Children -Revised (SASC-R), and the Child Behavior Checklist (CBCL) in a sample of fifty-four high-functioning subjects with autism or Asperger syndrome (HFA/AS) (M = 11.2 ± 1.7 years) and 305 community subjects (M = 12.2 ± 2.2 years). Children and adolescents completed the SPAI-C and SASC-R, and their parents completed the CBCL Internalizing scale. Adolescents with HFA/AS scored higher than the community sample on all measures. Behavioural avoidance and evaluative social anxiety increased by age within the HFA/AS group, whereas behavioural avoidance decreased by age in control participants. Data support that HFA/AS in adolescents may be associated with clinically relevant social anxiety symptoms. En ligne : http://dx.doi.org/10.1007/s10803-008-0555-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=605
in Journal of Autism and Developmental Disorders > 38-9 (October 2008) . - p.1697-1709[article] Social Anxiety in High-functioning Children and Adolescents with Autism and Asperger Syndrome [Texte imprimé et/ou numérique] / Sanna KUUSIKKO, Auteur ; Alice S. CARTER, Auteur ; Katja JUSSILA, Auteur ; Marja-Leena MATTILA, Auteur ; Hanna EBELING, Auteur ; Irma MOILANEN, Auteur ; David L. PAULS, Auteur ; Rachel POLLOCK-WURMAN, Auteur . - 2008 . - p.1697-1709.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 38-9 (October 2008) . - p.1697-1709
Mots-clés : Asperger-syndrome High-functioning-autism Social-anxiety Social-phobia Index. décimale : PER Périodiques Résumé : We examined social anxiety and internalizing symptoms using the Social Phobia and Anxiety Inventory for Children (SPAI-C), the Social Anxiety Scale for Children -Revised (SASC-R), and the Child Behavior Checklist (CBCL) in a sample of fifty-four high-functioning subjects with autism or Asperger syndrome (HFA/AS) (M = 11.2 ± 1.7 years) and 305 community subjects (M = 12.2 ± 2.2 years). Children and adolescents completed the SPAI-C and SASC-R, and their parents completed the CBCL Internalizing scale. Adolescents with HFA/AS scored higher than the community sample on all measures. Behavioural avoidance and evaluative social anxiety increased by age within the HFA/AS group, whereas behavioural avoidance decreased by age in control participants. Data support that HFA/AS in adolescents may be associated with clinically relevant social anxiety symptoms. En ligne : http://dx.doi.org/10.1007/s10803-008-0555-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=605 Social Anxiety in Parents of High-Functioning Children with Autism and Asperger Syndrome / Sanna KUUSIKKO-GAUFFIN in Journal of Autism and Developmental Disorders, 43-3 (March 2013)
[article]
Titre : Social Anxiety in Parents of High-Functioning Children with Autism and Asperger Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Sanna KUUSIKKO-GAUFFIN, Auteur ; Rachel POLLOCK-WURMAN, Auteur ; Marja-Leena MATTILA, Auteur ; Katja JUSSILA, Auteur ; Hanna EBELING, Auteur ; David L. PAULS, Auteur ; Irma MOILANEN, Auteur Article en page(s) : p.521-529 Langues : Anglais (eng) Mots-clés : Adult Age Autism spectrum disorders Gender Social anxiety SPAI Index. décimale : PER Périodiques Résumé : We evaluated social anxiety (SA) symptoms in parents of children with autism spectrum disorders (ASDs; N = 131) and community parents (N = 597) using the Social Phobia and Anxiety Inventory (SPAI). SA was significantly more common in ASD than control mothers (15.6 vs. 6.7 %) and more equal between the ASD and control fathers (3.3 vs. 4.8 %). The ASD mothers scored significantly higher than control mothers on all SPAI scales. ASD fathers scored significantly higher than control fathers on the somatic, cognitive, avoidance and agoraphobic symptoms of SA. It is of clinical import to support ASD parents’ well-being as their psychiatric features may contribute greatly to their children’s emotional development and the well-being of the whole family. En ligne : http://dx.doi.org/10.1007/s10803-012-1581-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192
in Journal of Autism and Developmental Disorders > 43-3 (March 2013) . - p.521-529[article] Social Anxiety in Parents of High-Functioning Children with Autism and Asperger Syndrome [Texte imprimé et/ou numérique] / Sanna KUUSIKKO-GAUFFIN, Auteur ; Rachel POLLOCK-WURMAN, Auteur ; Marja-Leena MATTILA, Auteur ; Katja JUSSILA, Auteur ; Hanna EBELING, Auteur ; David L. PAULS, Auteur ; Irma MOILANEN, Auteur . - p.521-529.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 43-3 (March 2013) . - p.521-529
Mots-clés : Adult Age Autism spectrum disorders Gender Social anxiety SPAI Index. décimale : PER Périodiques Résumé : We evaluated social anxiety (SA) symptoms in parents of children with autism spectrum disorders (ASDs; N = 131) and community parents (N = 597) using the Social Phobia and Anxiety Inventory (SPAI). SA was significantly more common in ASD than control mothers (15.6 vs. 6.7 %) and more equal between the ASD and control fathers (3.3 vs. 4.8 %). The ASD mothers scored significantly higher than control mothers on all SPAI scales. ASD fathers scored significantly higher than control fathers on the somatic, cognitive, avoidance and agoraphobic symptoms of SA. It is of clinical import to support ASD parents’ well-being as their psychiatric features may contribute greatly to their children’s emotional development and the well-being of the whole family. En ligne : http://dx.doi.org/10.1007/s10803-012-1581-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192 Use of Context in Pragmatic Language Comprehension by Children with Asperger Syndrome or High-Functioning Autism / Soile LOUKUSA in Journal of Autism and Developmental Disorders, 37-6 (July 2007)
PermalinkUse of early intervention for young children with autism spectrum disorder across Europe / Erica SALOMONE in Autism, 20-2 (February 2016)
PermalinkValence Scaling of Dynamic Facial Expressions is Altered in High-Functioning Subjects with Autism Spectrum Disorders: an fMRI Study / Jukka S. RAHKO in Journal of Autism and Developmental Disorders, 42-6 (June 2012)
PermalinkValidation of the Finnish Autism Spectrum Screening Questionnaire (ASSQ) for Clinical Settings and Total Population Screening / Marja-Leena MATTILA in Journal of Autism and Developmental Disorders, 42-10 (October 2012)
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