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Auteur Karla VAN LEEUWEN |
Documents disponibles écrits par cet auteur (5)



Behavior problems among school-aged children with autism spectrum disorder: Associations with children's communication difficulties and parenting behaviors / Hannah BOONEN in Research in Autism Spectrum Disorders, 8-6 (June 2014)
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[article]
Titre : Behavior problems among school-aged children with autism spectrum disorder: Associations with children's communication difficulties and parenting behaviors Type de document : Texte imprimé et/ou numérique Auteurs : Hannah BOONEN, Auteur ; Jarymke MALJAARS, Auteur ; Greet LAMBRECHTS, Auteur ; Inge ZINK, Auteur ; Karla VAN LEEUWEN, Auteur ; Ilse NOENS, Auteur Article en page(s) : p.716-725 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Externalizing behavior problems Internalizing behavior problems Communication difficulties Parenting behaviors Index. décimale : PER Périodiques Résumé : Research has clearly demonstrated that behavior problems are common among children with ASD. These co-occurring behavior problems place children with ASD and their families at risk for a range of negative outcomes. This questionnaire study aimed to investigate whether and how age, gender, and communication difficulties at the child level and parenting behaviors at the family level are associated with externalizing and internalizing problems among children with ASD (n = 206) and without ASD (n = 187) aged 6–12 years. Results indicated that pragmatic language difficulties of the child and negative controlling parenting behaviors both made a significant and unique contribution to externalizing behavior problems for the ASD group. In the control group, chronological age and pragmatic language difficulties were the most robust concurrent predictors of externalizing problems. With regard to internalizing problems, pragmatic language difficulties and ASD adapted parenting behaviors were significant predictors for both the ASD and control group. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.03.008 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232
in Research in Autism Spectrum Disorders > 8-6 (June 2014) . - p.716-725[article] Behavior problems among school-aged children with autism spectrum disorder: Associations with children's communication difficulties and parenting behaviors [Texte imprimé et/ou numérique] / Hannah BOONEN, Auteur ; Jarymke MALJAARS, Auteur ; Greet LAMBRECHTS, Auteur ; Inge ZINK, Auteur ; Karla VAN LEEUWEN, Auteur ; Ilse NOENS, Auteur . - p.716-725.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 8-6 (June 2014) . - p.716-725
Mots-clés : Autism spectrum disorder Externalizing behavior problems Internalizing behavior problems Communication difficulties Parenting behaviors Index. décimale : PER Périodiques Résumé : Research has clearly demonstrated that behavior problems are common among children with ASD. These co-occurring behavior problems place children with ASD and their families at risk for a range of negative outcomes. This questionnaire study aimed to investigate whether and how age, gender, and communication difficulties at the child level and parenting behaviors at the family level are associated with externalizing and internalizing problems among children with ASD (n = 206) and without ASD (n = 187) aged 6–12 years. Results indicated that pragmatic language difficulties of the child and negative controlling parenting behaviors both made a significant and unique contribution to externalizing behavior problems for the ASD group. In the control group, chronological age and pragmatic language difficulties were the most robust concurrent predictors of externalizing problems. With regard to internalizing problems, pragmatic language difficulties and ASD adapted parenting behaviors were significant predictors for both the ASD and control group. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.03.008 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232 Gene-based interaction analysis shows GABAergic genes interacting with parenting in adolescent depressive symptoms / Evelien VAN ASSCHE in Journal of Child Psychology and Psychiatry, 58-12 (December 2017)
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Titre : Gene-based interaction analysis shows GABAergic genes interacting with parenting in adolescent depressive symptoms Type de document : Texte imprimé et/ou numérique Auteurs : Evelien VAN ASSCHE, Auteur ; Tim MOONS, Auteur ; Ozan CINAR, Auteur ; Wolfgang VIECHTBAUER, Auteur ; Albertine J. OLDEHINKEL, Auteur ; Karla VAN LEEUWEN, Auteur ; Karine VERSCHUEREN, Auteur ; Hilde COLPIN, Auteur ; Diether LAMBRECHTS, Auteur ; Wim VAN DEN NOORTGATE, Auteur ; Luc GOOSSENS, Auteur ; Stephan CLAES, Auteur ; Ruud VAN WINKEL, Auteur Article en page(s) : p.1301-1309 Langues : Anglais (eng) Mots-clés : Gene–environment interaction polygenic parenting gene-based testing adolescents depression Index. décimale : PER Périodiques Résumé : Background Most gene-environment interaction studies (G × E) have focused on single candidate genes. This approach is criticized for its expectations of large effect sizes and occurrence of spurious results. We describe an approach that accounts for the polygenic nature of most psychiatric phenotypes and reduces the risk of false-positive findings. We apply this method focusing on the role of perceived parental support, psychological control, and harsh punishment in depressive symptoms in adolescence. Methods Analyses were conducted on 982 adolescents of Caucasian origin (Mage (SD) = 13.78 (.94) years) genotyped for 4,947 SNPs in 263 genes, selected based on a literature survey. The Leuven Adolescent Perceived Parenting Scale (LAPPS) and the Parental Behavior Scale (PBS) were used to assess perceived parental psychological control, harsh punishment, and support. The Center for Epidemiologic Studies Depression Scale (CES-D) was the outcome. We used gene-based testing taking into account linkage disequilibrium to identify genes containing SNPs exhibiting an interaction with environmental factors yielding a p-value per single gene. Significant results at the corrected p-value of p < 1.90 × 10?4 were examined in an independent replication sample of Dutch adolescents (N = 1354). Results Two genes showed evidence for interaction with perceived support: GABRR1 (p = 4.62 × 10?5) and GABRR2 (p = 9.05 × 10?6). No genes interacted significantly with psychological control or harsh punishment. Gene-based analysis was unable to confirm the interaction of GABRR1 or GABRR2 with support in the replication sample. However, for GABRR2, but not GABRR1, the correlation of the estimates between the two datasets was significant (r (46) = .32; p = .027) and a gene-based analysis of the combined datasets supported GABRR2 × support interaction (p = 1.63 × 10?4). Conclusions We present a gene-based method for gene–environment interactions in a polygenic context and show that genes interact differently with particular aspects of parenting. This accentuates the importance of polygenic approaches and the need to accurately assess environmental exposure in G × E. En ligne : http://dx.doi.org/10.1111/jcpp.12766 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326
in Journal of Child Psychology and Psychiatry > 58-12 (December 2017) . - p.1301-1309[article] Gene-based interaction analysis shows GABAergic genes interacting with parenting in adolescent depressive symptoms [Texte imprimé et/ou numérique] / Evelien VAN ASSCHE, Auteur ; Tim MOONS, Auteur ; Ozan CINAR, Auteur ; Wolfgang VIECHTBAUER, Auteur ; Albertine J. OLDEHINKEL, Auteur ; Karla VAN LEEUWEN, Auteur ; Karine VERSCHUEREN, Auteur ; Hilde COLPIN, Auteur ; Diether LAMBRECHTS, Auteur ; Wim VAN DEN NOORTGATE, Auteur ; Luc GOOSSENS, Auteur ; Stephan CLAES, Auteur ; Ruud VAN WINKEL, Auteur . - p.1301-1309.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 58-12 (December 2017) . - p.1301-1309
Mots-clés : Gene–environment interaction polygenic parenting gene-based testing adolescents depression Index. décimale : PER Périodiques Résumé : Background Most gene-environment interaction studies (G × E) have focused on single candidate genes. This approach is criticized for its expectations of large effect sizes and occurrence of spurious results. We describe an approach that accounts for the polygenic nature of most psychiatric phenotypes and reduces the risk of false-positive findings. We apply this method focusing on the role of perceived parental support, psychological control, and harsh punishment in depressive symptoms in adolescence. Methods Analyses were conducted on 982 adolescents of Caucasian origin (Mage (SD) = 13.78 (.94) years) genotyped for 4,947 SNPs in 263 genes, selected based on a literature survey. The Leuven Adolescent Perceived Parenting Scale (LAPPS) and the Parental Behavior Scale (PBS) were used to assess perceived parental psychological control, harsh punishment, and support. The Center for Epidemiologic Studies Depression Scale (CES-D) was the outcome. We used gene-based testing taking into account linkage disequilibrium to identify genes containing SNPs exhibiting an interaction with environmental factors yielding a p-value per single gene. Significant results at the corrected p-value of p < 1.90 × 10?4 were examined in an independent replication sample of Dutch adolescents (N = 1354). Results Two genes showed evidence for interaction with perceived support: GABRR1 (p = 4.62 × 10?5) and GABRR2 (p = 9.05 × 10?6). No genes interacted significantly with psychological control or harsh punishment. Gene-based analysis was unable to confirm the interaction of GABRR1 or GABRR2 with support in the replication sample. However, for GABRR2, but not GABRR1, the correlation of the estimates between the two datasets was significant (r (46) = .32; p = .027) and a gene-based analysis of the combined datasets supported GABRR2 × support interaction (p = 1.63 × 10?4). Conclusions We present a gene-based method for gene–environment interactions in a polygenic context and show that genes interact differently with particular aspects of parenting. This accentuates the importance of polygenic approaches and the need to accurately assess environmental exposure in G × E. En ligne : http://dx.doi.org/10.1111/jcpp.12766 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326 Mothers’ Parenting Behaviors in Families of School-Aged Children with Autism Spectrum Disorder: An Observational and Questionnaire Study / Hannah BOONEN in Journal of Autism and Developmental Disorders, 45-11 (November 2015)
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Titre : Mothers’ Parenting Behaviors in Families of School-Aged Children with Autism Spectrum Disorder: An Observational and Questionnaire Study Type de document : Texte imprimé et/ou numérique Auteurs : Hannah BOONEN, Auteur ; Lotte VAN ESCH, Auteur ; Greet LAMBRECHTS, Auteur ; Jarymke MALJAARS, Auteur ; Inge ZINK, Auteur ; Karla VAN LEEUWEN, Auteur ; Ilse NOENS, Auteur Article en page(s) : p.3580-3593 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Parenting behaviors Observation Questionnaire Parenting stress Index. décimale : PER Périodiques Résumé : Although parents of children with ASD face specific challenges in parenting, only a few studies have empirically investigated parenting behaviors among these parents. The current study examined differences in parenting behaviors between mothers of school-aged children with ASD (n = 30) and mothers of typically developing children (n = 39), using both an observational measure and a self-report questionnaire. Results indicated that mothers of children with ASD obtained significantly lower scores on Sensitivity and Provision of structure as measured during the observation. They reported significantly higher scores on Material rewarding and Adapting the environment on the questionnaire. When controlling for parenting stress, the group differences on Sensitivity and Material rewarding did not remain significant. En ligne : http://dx.doi.org/10.1007/s10803-015-2506-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270
in Journal of Autism and Developmental Disorders > 45-11 (November 2015) . - p.3580-3593[article] Mothers’ Parenting Behaviors in Families of School-Aged Children with Autism Spectrum Disorder: An Observational and Questionnaire Study [Texte imprimé et/ou numérique] / Hannah BOONEN, Auteur ; Lotte VAN ESCH, Auteur ; Greet LAMBRECHTS, Auteur ; Jarymke MALJAARS, Auteur ; Inge ZINK, Auteur ; Karla VAN LEEUWEN, Auteur ; Ilse NOENS, Auteur . - p.3580-3593.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-11 (November 2015) . - p.3580-3593
Mots-clés : Autism spectrum disorder Parenting behaviors Observation Questionnaire Parenting stress Index. décimale : PER Périodiques Résumé : Although parents of children with ASD face specific challenges in parenting, only a few studies have empirically investigated parenting behaviors among these parents. The current study examined differences in parenting behaviors between mothers of school-aged children with ASD (n = 30) and mothers of typically developing children (n = 39), using both an observational measure and a self-report questionnaire. Results indicated that mothers of children with ASD obtained significantly lower scores on Sensitivity and Provision of structure as measured during the observation. They reported significantly higher scores on Material rewarding and Adapting the environment on the questionnaire. When controlling for parenting stress, the group differences on Sensitivity and Material rewarding did not remain significant. En ligne : http://dx.doi.org/10.1007/s10803-015-2506-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270 Parenting behaviours among mothers of pre-schoolers on the autism spectrum: Associations with parenting stress and children’s externalising behaviour problems / Melinda MADAREVIC in Research in Autism Spectrum Disorders, 90 (February 2022)
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Titre : Parenting behaviours among mothers of pre-schoolers on the autism spectrum: Associations with parenting stress and children’s externalising behaviour problems Type de document : Texte imprimé et/ou numérique Auteurs : Melinda MADAREVIC, Auteur ; Lotte VAN ESCH, Auteur ; Greet LAMBRECHTS, Auteur ; Eva CEULEMANS, Auteur ; Karla VAN LEEUWEN, Auteur ; Ilse NOENS, Auteur Article en page(s) : 101901 Langues : Anglais (eng) Mots-clés : Parenting behaviours Parenting stress Externalising behaviour problems Autism Pre-schoolers Index. décimale : PER Périodiques Résumé : Background Parents of pre-schoolers diagnosed with Autism Spectrum Disorder (ASD) report increased parenting stress (i.e., stress related to the parent role) and more behaviour problems of the child compared with parents of non-autistic pre-schoolers. Parenting stress and children’s behaviour problems are both associated with parenting behaviours, but have not yet been investigated together. Method 42 mothers of autistic and non-autistic pre-schoolers were observed during mother-child interaction and they reported on parenting behaviours, parenting stress, and children’s externalising behaviour problems. Spearman correlations between all variables were calculated for the ASD group and the non-ASD group separately, and Linear Mixed Models were built to investigate whether parenting stress and externalising behaviour problems were similarly associated to parenting behaviours in both groups. Results Mothers in the ASD group reported more parenting stress and more externalising behaviour problems than mothers in the non-ASD group. In the ASD group only, parenting stress was related to externalising behaviour problems but not to the level of autism characteristics. In both groups, more externalising behaviour problems were associated with more observed negative parenting behaviours (i.e., criticising and ignoring the child), and more parenting stress was associated with less reported autonomy support. Conclusions Our findings indicate that in the case of possibly problematic parenting behaviours, such as negativity and lack of autonomy support, it is important to investigate associated factors like parenting stress and children’s behaviour problems. An individualised strengths and needs assessment could then offer a tailored intervention to families with an autistic pre-schooler. En ligne : https://doi.org/10.1016/j.rasd.2021.101901 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458
in Research in Autism Spectrum Disorders > 90 (February 2022) . - 101901[article] Parenting behaviours among mothers of pre-schoolers on the autism spectrum: Associations with parenting stress and children’s externalising behaviour problems [Texte imprimé et/ou numérique] / Melinda MADAREVIC, Auteur ; Lotte VAN ESCH, Auteur ; Greet LAMBRECHTS, Auteur ; Eva CEULEMANS, Auteur ; Karla VAN LEEUWEN, Auteur ; Ilse NOENS, Auteur . - 101901.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 90 (February 2022) . - 101901
Mots-clés : Parenting behaviours Parenting stress Externalising behaviour problems Autism Pre-schoolers Index. décimale : PER Périodiques Résumé : Background Parents of pre-schoolers diagnosed with Autism Spectrum Disorder (ASD) report increased parenting stress (i.e., stress related to the parent role) and more behaviour problems of the child compared with parents of non-autistic pre-schoolers. Parenting stress and children’s behaviour problems are both associated with parenting behaviours, but have not yet been investigated together. Method 42 mothers of autistic and non-autistic pre-schoolers were observed during mother-child interaction and they reported on parenting behaviours, parenting stress, and children’s externalising behaviour problems. Spearman correlations between all variables were calculated for the ASD group and the non-ASD group separately, and Linear Mixed Models were built to investigate whether parenting stress and externalising behaviour problems were similarly associated to parenting behaviours in both groups. Results Mothers in the ASD group reported more parenting stress and more externalising behaviour problems than mothers in the non-ASD group. In the ASD group only, parenting stress was related to externalising behaviour problems but not to the level of autism characteristics. In both groups, more externalising behaviour problems were associated with more observed negative parenting behaviours (i.e., criticising and ignoring the child), and more parenting stress was associated with less reported autonomy support. Conclusions Our findings indicate that in the case of possibly problematic parenting behaviours, such as negativity and lack of autonomy support, it is important to investigate associated factors like parenting stress and children’s behaviour problems. An individualised strengths and needs assessment could then offer a tailored intervention to families with an autistic pre-schooler. En ligne : https://doi.org/10.1016/j.rasd.2021.101901 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 The association between parenting behaviours of mothers of adolescents with autism spectrum disorder and adolescent and mother characteristics / Lotte VAN ESCH in Research in Autism Spectrum Disorders, 65 (September 2019)
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Titre : The association between parenting behaviours of mothers of adolescents with autism spectrum disorder and adolescent and mother characteristics Type de document : Texte imprimé et/ou numérique Auteurs : Lotte VAN ESCH, Auteur ; Eva CEULEMANS, Auteur ; Karla VAN LEEUWEN, Auteur ; Ilse NOENS, Auteur Article en page(s) : p.46-55 Langues : Anglais (eng) Mots-clés : ASD Parenting behaviour Adolescents Behaviour problems Observation Questionnaire Index. décimale : PER Périodiques Résumé : Background Studies on parenting behaviours among parents of adolescents with ASD either used parenting behaviours that were supported in the general population, or specific ASD related parenting behaviours. This study aimed to identify which parenting components underlie parenting behaviours among parents of adolescents with ASD, and how these components relate to adolescent and mother characteristics. Method 35 children with ASD and 38 children without ASD (aged 12–16 years old) participated with their mother in this cross-sectional study. Parenting behaviour was measured based on observations. Principal components analyses (PCA) were carried out to construct parenting components. Pearson correlations were calculated for the ASD and General Population Control (GPC) group separately to investigate the relationship between the parenting components and adolescent and mother characteristics. Results In both groups, PCAs on observed parenting behaviours yielded the components Parental Support and Behavioural Control. However, in the ASD group, Negativity was generated as a third cluster. Results indicated that only verbal IQ was significantly correlated with parenting behaviour components. Conclusions This study suggests that the framework of parenting behaviours in the general literature is applicable to parents of children with ASD. Furthermore, associations between parenting behaviours and adolescent characteristics were rather modest in the ASD group. En ligne : https://doi.org/10.1016/j.rasd.2019.05.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=401
in Research in Autism Spectrum Disorders > 65 (September 2019) . - p.46-55[article] The association between parenting behaviours of mothers of adolescents with autism spectrum disorder and adolescent and mother characteristics [Texte imprimé et/ou numérique] / Lotte VAN ESCH, Auteur ; Eva CEULEMANS, Auteur ; Karla VAN LEEUWEN, Auteur ; Ilse NOENS, Auteur . - p.46-55.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 65 (September 2019) . - p.46-55
Mots-clés : ASD Parenting behaviour Adolescents Behaviour problems Observation Questionnaire Index. décimale : PER Périodiques Résumé : Background Studies on parenting behaviours among parents of adolescents with ASD either used parenting behaviours that were supported in the general population, or specific ASD related parenting behaviours. This study aimed to identify which parenting components underlie parenting behaviours among parents of adolescents with ASD, and how these components relate to adolescent and mother characteristics. Method 35 children with ASD and 38 children without ASD (aged 12–16 years old) participated with their mother in this cross-sectional study. Parenting behaviour was measured based on observations. Principal components analyses (PCA) were carried out to construct parenting components. Pearson correlations were calculated for the ASD and General Population Control (GPC) group separately to investigate the relationship between the parenting components and adolescent and mother characteristics. Results In both groups, PCAs on observed parenting behaviours yielded the components Parental Support and Behavioural Control. However, in the ASD group, Negativity was generated as a third cluster. Results indicated that only verbal IQ was significantly correlated with parenting behaviour components. Conclusions This study suggests that the framework of parenting behaviours in the general literature is applicable to parents of children with ASD. Furthermore, associations between parenting behaviours and adolescent characteristics were rather modest in the ASD group. En ligne : https://doi.org/10.1016/j.rasd.2019.05.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=401