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An Electrophysiological Investigation of Interhemispheric Transfer Time in Children and Adolescents with High-Functioning Autism Spectrum Disorders / Ann CLAWSON in Journal of Autism and Developmental Disorders, 45-2 (February 2015)
[article]
Titre : An Electrophysiological Investigation of Interhemispheric Transfer Time in Children and Adolescents with High-Functioning Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Ann CLAWSON, Auteur ; Peter E. CLAYSON, Auteur ; Mikle SOUTH, Auteur ; Erin D. BIGLER, Auteur ; Michael J. LARSON, Auteur Article en page(s) : p.363-375 Langues : Anglais (eng) Mots-clés : Autism Interhemispheric transfer time N1 P1 Event-related potential Corpus callosum White matter Index. décimale : PER Périodiques Résumé : Little is known about the functional impact of putative deficits in white-matter connectivity across the corpus callosum (CC) in individuals with autism spectrum disorders (ASDs). We utilized the temporal sensitivity of event-related potentials to examine the interhemispheric transfer time (IHTT) of basic visual information across the CC in youth with high-functioning ASD relative to healthy controls. We conducted two experiments: a visual letter matching experiment (n = 46) and a visual picture matching experiment, (n = 48) and utilized both electrophysiological (N1 and P1 amplitudes and latencies) and behavioral [response times (RTs), error rates] indices of IHTT. There were no significant group differences on either experiment for RTs, error rates, or N1 and P1 latencies, suggesting that on basic tasks the timing of information flow across the CC may not be altered in high functioning ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1895-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258
in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.363-375[article] An Electrophysiological Investigation of Interhemispheric Transfer Time in Children and Adolescents with High-Functioning Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Ann CLAWSON, Auteur ; Peter E. CLAYSON, Auteur ; Mikle SOUTH, Auteur ; Erin D. BIGLER, Auteur ; Michael J. LARSON, Auteur . - p.363-375.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.363-375
Mots-clés : Autism Interhemispheric transfer time N1 P1 Event-related potential Corpus callosum White matter Index. décimale : PER Périodiques Résumé : Little is known about the functional impact of putative deficits in white-matter connectivity across the corpus callosum (CC) in individuals with autism spectrum disorders (ASDs). We utilized the temporal sensitivity of event-related potentials to examine the interhemispheric transfer time (IHTT) of basic visual information across the CC in youth with high-functioning ASD relative to healthy controls. We conducted two experiments: a visual letter matching experiment (n = 46) and a visual picture matching experiment, (n = 48) and utilized both electrophysiological (N1 and P1 amplitudes and latencies) and behavioral [response times (RTs), error rates] indices of IHTT. There were no significant group differences on either experiment for RTs, error rates, or N1 and P1 latencies, suggesting that on basic tasks the timing of information flow across the CC may not be altered in high functioning ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1895-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 Attenuated Auditory Event-Related Potentials and Associations with Atypical Sensory Response Patterns in Children with Autism / Franc C L. DONKERS in Journal of Autism and Developmental Disorders, 45-2 (February 2015)
[article]
Titre : Attenuated Auditory Event-Related Potentials and Associations with Atypical Sensory Response Patterns in Children with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Franc C L. DONKERS, Auteur ; Sarah E. SCHIPUL, Auteur ; Grace T. BARANEK, Auteur ; Katherine M. CLEARY, Auteur ; Michael T. WILLOUGHBY, Auteur ; Anna M. EVANS, Auteur ; John C. BULLUCK, Auteur ; Jeanne E. LOVMO, Auteur ; Aysenil BELGER, Auteur Article en page(s) : p.506-523 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Sensory processing Event-related potentials P1 N2 P3a Index. décimale : PER Périodiques Résumé : Neurobiological underpinnings of unusual sensory features in individuals with autism are unknown. Event-related potentials elicited by task-irrelevant sounds were used to elucidate neural correlates of auditory processing and associations with three common sensory response patterns (hyperresponsiveness; hyporesponsiveness; sensory seeking). Twenty-eight children with autism and 39 typically developing children (4–12 year-olds) completed an auditory oddball paradigm. Results revealed marginally attenuated P1 and N2 to standard tones and attenuated P3a to novel sounds in autism versus controls. Exploratory analyses suggested that within the autism group, attenuated N2 and P3a amplitudes were associated with greater sensory seeking behaviors for specific ranges of P1 responses. Findings suggest that attenuated early sensory as well as later attention-orienting neural responses to stimuli may underlie selective sensory features via complex mechanisms. En ligne : http://dx.doi.org/10.1007/s10803-013-1948-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258
in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.506-523[article] Attenuated Auditory Event-Related Potentials and Associations with Atypical Sensory Response Patterns in Children with Autism [Texte imprimé et/ou numérique] / Franc C L. DONKERS, Auteur ; Sarah E. SCHIPUL, Auteur ; Grace T. BARANEK, Auteur ; Katherine M. CLEARY, Auteur ; Michael T. WILLOUGHBY, Auteur ; Anna M. EVANS, Auteur ; John C. BULLUCK, Auteur ; Jeanne E. LOVMO, Auteur ; Aysenil BELGER, Auteur . - p.506-523.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.506-523
Mots-clés : Autism spectrum disorder Sensory processing Event-related potentials P1 N2 P3a Index. décimale : PER Périodiques Résumé : Neurobiological underpinnings of unusual sensory features in individuals with autism are unknown. Event-related potentials elicited by task-irrelevant sounds were used to elucidate neural correlates of auditory processing and associations with three common sensory response patterns (hyperresponsiveness; hyporesponsiveness; sensory seeking). Twenty-eight children with autism and 39 typically developing children (4–12 year-olds) completed an auditory oddball paradigm. Results revealed marginally attenuated P1 and N2 to standard tones and attenuated P3a to novel sounds in autism versus controls. Exploratory analyses suggested that within the autism group, attenuated N2 and P3a amplitudes were associated with greater sensory seeking behaviors for specific ranges of P1 responses. Findings suggest that attenuated early sensory as well as later attention-orienting neural responses to stimuli may underlie selective sensory features via complex mechanisms. En ligne : http://dx.doi.org/10.1007/s10803-013-1948-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 Don't touch me! autistic traits modulate early and late ERP components during visual perception of social touch / Leehe PELED-AVRON in Autism Research, 10-6 (June 2017)
[article]
Titre : Don't touch me! autistic traits modulate early and late ERP components during visual perception of social touch Type de document : Texte imprimé et/ou numérique Auteurs : Leehe PELED-AVRON, Auteur ; Simone G. SHAMAY-TSOORY, Auteur Article en page(s) : p.1141-1154 Langues : Anglais (eng) Mots-clés : autistic traits interpersonal touch ERP LPP P1 Index. décimale : PER Périodiques Résumé : Although individuals with autism spectrum disorder (ASD) have impaired responses to interpersonal touch, the underlying neural correlates remain largely unknown. Here, we examined the neural correlates that underlie interpersonal touch perception in individuals with either high or low autistic traits. Fifty-three participants were classified as having either high or low autistic traits based on their performance on the autism quotient (AQ) questionnaire. We hypothesized that individuals with high AQ scores would have relatively high touch hypervigilance, reflected as earlier P1 and stronger late positive potential (LPP) responses, two components of event-related potentials that serve as electrophysiological markers of anxiety bias. We recorded each participant's electroencephalography activity during presentation of images depicting human touch, object touch, and non-touch control images. Consistent with our hypothesis, AQ scores were positively correlated with social touch aversion. Moreover, participants with high AQ scores had earlier P1 and stronger LPP responses when presented with human touch compared to the control images. Importantly, a regression model revealed that earlier P1 and larger LPP amplitude measured during social touch observation can accurately predict higher autistic trait levels. Taken together, these findings indicate that individuals with high levels of autistic traits may have a hypervigilant response to observed social touch. En ligne : http://dx.doi.org/10.1002/aur.1762 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309
in Autism Research > 10-6 (June 2017) . - p.1141-1154[article] Don't touch me! autistic traits modulate early and late ERP components during visual perception of social touch [Texte imprimé et/ou numérique] / Leehe PELED-AVRON, Auteur ; Simone G. SHAMAY-TSOORY, Auteur . - p.1141-1154.
Langues : Anglais (eng)
in Autism Research > 10-6 (June 2017) . - p.1141-1154
Mots-clés : autistic traits interpersonal touch ERP LPP P1 Index. décimale : PER Périodiques Résumé : Although individuals with autism spectrum disorder (ASD) have impaired responses to interpersonal touch, the underlying neural correlates remain largely unknown. Here, we examined the neural correlates that underlie interpersonal touch perception in individuals with either high or low autistic traits. Fifty-three participants were classified as having either high or low autistic traits based on their performance on the autism quotient (AQ) questionnaire. We hypothesized that individuals with high AQ scores would have relatively high touch hypervigilance, reflected as earlier P1 and stronger late positive potential (LPP) responses, two components of event-related potentials that serve as electrophysiological markers of anxiety bias. We recorded each participant's electroencephalography activity during presentation of images depicting human touch, object touch, and non-touch control images. Consistent with our hypothesis, AQ scores were positively correlated with social touch aversion. Moreover, participants with high AQ scores had earlier P1 and stronger LPP responses when presented with human touch compared to the control images. Importantly, a regression model revealed that earlier P1 and larger LPP amplitude measured during social touch observation can accurately predict higher autistic trait levels. Taken together, these findings indicate that individuals with high levels of autistic traits may have a hypervigilant response to observed social touch. En ligne : http://dx.doi.org/10.1002/aur.1762 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309 Neurophysiological correlates of holistic face processing in adolescents with and without autism spectrum disorder / S. NAUMANN in Journal of Neurodevelopmental Disorders, 10-1 (December 2018)
[article]
Titre : Neurophysiological correlates of holistic face processing in adolescents with and without autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : S. NAUMANN, Auteur ; U. SENFTLEBEN, Auteur ; M. SANTHOSH, Auteur ; J. MCPARTLAND, Auteur ; S. J. WEBB, Auteur Année de publication : 2018 Article en page(s) : 27 p. Langues : Anglais (eng) Mots-clés : Asd Gamma-band activity Holistic face processing N170 P1 Index. décimale : PER Périodiques Résumé : BACKGROUND: Face processing has been found to be impaired in autism spectrum disorders (ASD). One hypothesis is that individuals with ASD engage in piecemeal compared to holistic face processing strategies. To investigate the role of possible impairments in holistic face processing in individuals with autism, the current study investigated behavioral and electroencephalography (EEG) correlates of face processing (P1/N170 and gamma-band activity) in adolescents with ASD and sex-, age-, and IQ-matched neurotypical controls. METHODS: Participants were presented with upright and inverted Mooney stimuli; black and white low information faces that are only perceived as faces when processed holistically. Participants indicated behaviorally the detection of a face. EEG was collected time-locked to the presentation of the stimuli. RESULTS: Adolescents with ASD perceived Mooney stimuli as faces suggesting ability to use holistic processing but displayed a lower face detection rate and slower response times. ERP components suggest slowed temporal processing of Mooney stimuli in the ASD compared to control group for P1 latency but no differences between groups for P1 amplitude and at the N170. Increases in gamma-band activity was similar during the perception of the Mooney images by group, but the ASD group showed prolonged temporal elevation in activity. CONCLUSION: Overall, our results suggest that adolescents with ASD were able to utilize holistic processing to perceive a face within the Mooney stimuli. Delays in early processing, marked by the P1, and elongated elevation in gamma activity indicate that the neural systems supporting holistic processing are slightly altered suggesting a less automatic and less efficient facial processing system. TRIAL REGISTRATION: Non-applicable. En ligne : http://dx.doi.org/10.1186/s11689-018-9244-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386
in Journal of Neurodevelopmental Disorders > 10-1 (December 2018) . - 27 p.[article] Neurophysiological correlates of holistic face processing in adolescents with and without autism spectrum disorder [Texte imprimé et/ou numérique] / S. NAUMANN, Auteur ; U. SENFTLEBEN, Auteur ; M. SANTHOSH, Auteur ; J. MCPARTLAND, Auteur ; S. J. WEBB, Auteur . - 2018 . - 27 p.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 10-1 (December 2018) . - 27 p.
Mots-clés : Asd Gamma-band activity Holistic face processing N170 P1 Index. décimale : PER Périodiques Résumé : BACKGROUND: Face processing has been found to be impaired in autism spectrum disorders (ASD). One hypothesis is that individuals with ASD engage in piecemeal compared to holistic face processing strategies. To investigate the role of possible impairments in holistic face processing in individuals with autism, the current study investigated behavioral and electroencephalography (EEG) correlates of face processing (P1/N170 and gamma-band activity) in adolescents with ASD and sex-, age-, and IQ-matched neurotypical controls. METHODS: Participants were presented with upright and inverted Mooney stimuli; black and white low information faces that are only perceived as faces when processed holistically. Participants indicated behaviorally the detection of a face. EEG was collected time-locked to the presentation of the stimuli. RESULTS: Adolescents with ASD perceived Mooney stimuli as faces suggesting ability to use holistic processing but displayed a lower face detection rate and slower response times. ERP components suggest slowed temporal processing of Mooney stimuli in the ASD compared to control group for P1 latency but no differences between groups for P1 amplitude and at the N170. Increases in gamma-band activity was similar during the perception of the Mooney images by group, but the ASD group showed prolonged temporal elevation in activity. CONCLUSION: Overall, our results suggest that adolescents with ASD were able to utilize holistic processing to perceive a face within the Mooney stimuli. Delays in early processing, marked by the P1, and elongated elevation in gamma activity indicate that the neural systems supporting holistic processing are slightly altered suggesting a less automatic and less efficient facial processing system. TRIAL REGISTRATION: Non-applicable. En ligne : http://dx.doi.org/10.1186/s11689-018-9244-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386 Atypical sensory reactivity influences auditory attentional control in adults with autism spectrum disorders / Debra S. KARHSON in Autism Research, 9-10 (October 2016)
[article]
Titre : Atypical sensory reactivity influences auditory attentional control in adults with autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Debra S. KARHSON, Auteur ; Edward J. GOLOB, Auteur Article en page(s) : p.1079-1092 Langues : Anglais (eng) Mots-clés : P50 P1 N100 autism attention EEG/ERP sensory reactivity Index. décimale : PER Périodiques Résumé : Frequent observations of atypical sensory reactivity in people with autism spectrum disorders (ASD) suggest that the perceptual experience of those on the Spectrum is dissimilar to neurotypicals. Moreover, variable attention abilities in people with ASD, ranging from good control to periods of high distractibility, may be related to atypical sensory reactivity. This study used auditory event-related potential (ERP) measures to evaluate top-down and bottom-up attentional processes as a function of perceptual load, and examined these factors with respect to sensory reactivity. Twenty-five age and IQ-matched participants (ASD: 22.5 year, SD?=?4.1 year; Controls: 22.8 year, SD?=?5.1 year) completed the Adolescent/Adult Sensory Profile prior to performing a modified 3-stimulus (target, non-target, and distractor) auditory oddball target detection task EEG was recorded during task completion. ERP analysis assessed early sensory processing (P50, ?50 ms latency; N100, ?100 ms latency), cognitive control (N200, ?200 ms latency), and attentional processing (P3a and P3b, ?300 ms latency). Behavioral data demonstrates participants with ASD and neurotypical performed similarly on auditory target detection, but diverged on sensory profiles. Target ERP measures associated with top-down control (P3b latency) significantly increased under greater load in controls, but not in participants with ASD. Early ERP responses associated with bottom-up attention (P50 amplitude) were positively correlated to increased sensory sensitivity. Findings suggest specific neural mechanisms for increased perceptual capacity and enhanced bottom-up processing of sensory stimuli in people with autism. Results from participants with ASD are consistent with load theory and enhanced perceptual functioning. En ligne : http://dx.doi.org/10.1002/aur.1593 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294
in Autism Research > 9-10 (October 2016) . - p.1079-1092[article] Atypical sensory reactivity influences auditory attentional control in adults with autism spectrum disorders [Texte imprimé et/ou numérique] / Debra S. KARHSON, Auteur ; Edward J. GOLOB, Auteur . - p.1079-1092.
Langues : Anglais (eng)
in Autism Research > 9-10 (October 2016) . - p.1079-1092
Mots-clés : P50 P1 N100 autism attention EEG/ERP sensory reactivity Index. décimale : PER Périodiques Résumé : Frequent observations of atypical sensory reactivity in people with autism spectrum disorders (ASD) suggest that the perceptual experience of those on the Spectrum is dissimilar to neurotypicals. Moreover, variable attention abilities in people with ASD, ranging from good control to periods of high distractibility, may be related to atypical sensory reactivity. This study used auditory event-related potential (ERP) measures to evaluate top-down and bottom-up attentional processes as a function of perceptual load, and examined these factors with respect to sensory reactivity. Twenty-five age and IQ-matched participants (ASD: 22.5 year, SD?=?4.1 year; Controls: 22.8 year, SD?=?5.1 year) completed the Adolescent/Adult Sensory Profile prior to performing a modified 3-stimulus (target, non-target, and distractor) auditory oddball target detection task EEG was recorded during task completion. ERP analysis assessed early sensory processing (P50, ?50 ms latency; N100, ?100 ms latency), cognitive control (N200, ?200 ms latency), and attentional processing (P3a and P3b, ?300 ms latency). Behavioral data demonstrates participants with ASD and neurotypical performed similarly on auditory target detection, but diverged on sensory profiles. Target ERP measures associated with top-down control (P3b latency) significantly increased under greater load in controls, but not in participants with ASD. Early ERP responses associated with bottom-up attention (P50 amplitude) were positively correlated to increased sensory sensitivity. Findings suggest specific neural mechanisms for increased perceptual capacity and enhanced bottom-up processing of sensory stimuli in people with autism. Results from participants with ASD are consistent with load theory and enhanced perceptual functioning. En ligne : http://dx.doi.org/10.1002/aur.1593 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294