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Interaction between manganese and GSTP1 in relation to autism spectrum disorder while controlling for exposure to mixture of lead, mercury, arsenic, and cadmium / Mohammad H. RAHBAR in Research in Autism Spectrum Disorders, 55 (November 2018)
[article]
Titre : Interaction between manganese and GSTP1 in relation to autism spectrum disorder while controlling for exposure to mixture of lead, mercury, arsenic, and cadmium Type de document : Texte imprimé et/ou numérique Auteurs : Mohammad H. RAHBAR, Auteur ; Maureen SAMMS-VAUGHAN, Auteur ; MinJae LEE, Auteur ; MacKinsey A. CHRISTIAN, Auteur ; Jan BRESSLER, Auteur ; Manouchehr HESSABI, Auteur ; Megan L. GROVE, Auteur ; Sydonnie SHAKESPEARE-PELLINGTON, Auteur ; Charlene COORE DESAI, Auteur ; Jody-Ann REECE, Auteur ; Katherine A. LOVELAND, Auteur ; Compton BEECHER, Auteur ; Wayne MCLAUGHLIN, Auteur ; Eric BOERWINKLE, Auteur Article en page(s) : p.50-63 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder (ASD) Heavy metals Interaction Weighted quantile sum (WQS) regression Index. décimale : PER Périodiques Résumé : Background We previously reported a significant interactive association between polymorphisms of GSTP1 and blood manganese concentrations (BMC) with autism spectrum disorder (ASD) in Jamaican children. In this paper, we investigate the same interactive association with ASD while adjusting for the mixture of four metals (lead, mercury, cadmium, and arsenic). Method We used data from 163 case-control pairs of children 2–8 years of age from our autism project in Jamaica, in which we collected blood for heavy metals analysis at enrollment. To minimize potential multicollinearity between concentrations of the four metals, we generated a mixture index using generalized weighted quantile sum regression, which was used in conditional logistic regression models to control for the four metals while assessing the interactive association between GSTP1 and BMC with ASD. Results Similar to the findings we reported previously, we found that in co-dominant and dominant models for GSTP1, among children with the Ile/Ile genotype, those with BMC???12??g/L had 4.6 and 4.27 times higher odds of ASD compared to those with BMC?12??g/L (adjusted Matched Odds Ratio (MOR)?=?4.6, 95% CI: 1.21–17.42 and adjusted MOR?=?4.27, 95% CI: 1.15–15.85, respectively). In the co-dominant model, for children with the Ile/Val and Val/Val genotypes, the adjusted MORs were 1.26 (95% CI: 0.32, 5.01) and 0.26 (95% CI: 0.05, 1.42), respectively. Conclusions After adjusting for the mixture of four metals, the interactive association of BMC and GSTP1 with ASD remained significant with similar magnitude of associations. Results should be interpreted cautiously. En ligne : https://doi.org/10.1016/j.rasd.2018.08.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369
in Research in Autism Spectrum Disorders > 55 (November 2018) . - p.50-63[article] Interaction between manganese and GSTP1 in relation to autism spectrum disorder while controlling for exposure to mixture of lead, mercury, arsenic, and cadmium [Texte imprimé et/ou numérique] / Mohammad H. RAHBAR, Auteur ; Maureen SAMMS-VAUGHAN, Auteur ; MinJae LEE, Auteur ; MacKinsey A. CHRISTIAN, Auteur ; Jan BRESSLER, Auteur ; Manouchehr HESSABI, Auteur ; Megan L. GROVE, Auteur ; Sydonnie SHAKESPEARE-PELLINGTON, Auteur ; Charlene COORE DESAI, Auteur ; Jody-Ann REECE, Auteur ; Katherine A. LOVELAND, Auteur ; Compton BEECHER, Auteur ; Wayne MCLAUGHLIN, Auteur ; Eric BOERWINKLE, Auteur . - p.50-63.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 55 (November 2018) . - p.50-63
Mots-clés : Autism spectrum disorder (ASD) Heavy metals Interaction Weighted quantile sum (WQS) regression Index. décimale : PER Périodiques Résumé : Background We previously reported a significant interactive association between polymorphisms of GSTP1 and blood manganese concentrations (BMC) with autism spectrum disorder (ASD) in Jamaican children. In this paper, we investigate the same interactive association with ASD while adjusting for the mixture of four metals (lead, mercury, cadmium, and arsenic). Method We used data from 163 case-control pairs of children 2–8 years of age from our autism project in Jamaica, in which we collected blood for heavy metals analysis at enrollment. To minimize potential multicollinearity between concentrations of the four metals, we generated a mixture index using generalized weighted quantile sum regression, which was used in conditional logistic regression models to control for the four metals while assessing the interactive association between GSTP1 and BMC with ASD. Results Similar to the findings we reported previously, we found that in co-dominant and dominant models for GSTP1, among children with the Ile/Ile genotype, those with BMC???12??g/L had 4.6 and 4.27 times higher odds of ASD compared to those with BMC?12??g/L (adjusted Matched Odds Ratio (MOR)?=?4.6, 95% CI: 1.21–17.42 and adjusted MOR?=?4.27, 95% CI: 1.15–15.85, respectively). In the co-dominant model, for children with the Ile/Val and Val/Val genotypes, the adjusted MORs were 1.26 (95% CI: 0.32, 5.01) and 0.26 (95% CI: 0.05, 1.42), respectively. Conclusions After adjusting for the mixture of four metals, the interactive association of BMC and GSTP1 with ASD remained significant with similar magnitude of associations. Results should be interpreted cautiously. En ligne : https://doi.org/10.1016/j.rasd.2018.08.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369 Interaction of Blood Manganese Concentrations with GSTT1 in Relation to Autism Spectrum Disorder in Jamaican Children / M. H. RAHBAR in Journal of Autism and Developmental Disorders, 51-6 (June 2021)
Children with Autism Spectrum Disorders Make a Fruit Salad with Probo, the Social Robot: An Interaction Study / Ramona E. SIMUT in Journal of Autism and Developmental Disorders, 46-1 (January 2016)
[article]
Titre : Children with Autism Spectrum Disorders Make a Fruit Salad with Probo, the Social Robot: An Interaction Study Type de document : Texte imprimé et/ou numérique Auteurs : Ramona E. SIMUT, Auteur ; Johan VANDERFAEILLIE, Auteur ; Andreea PECA, Auteur ; Greet PERRE, Auteur ; Bram VANDERBORGHT, Auteur Année de publication : 2016 Article en page(s) : p.113-126 Langues : Anglais (eng) Mots-clés : Children with ASD Social skills Social robots Interaction Robot assisted therapy Index. décimale : PER Périodiques Résumé : Social robots are thought to be motivating tools in play tasks with children with autism spectrum disorders. Thirty children with autism were included using a repeated measurements design. It was investigated if the children’s interaction with a human differed from the interaction with a social robot during a play task. Also, it was examined if the two conditions differed in their ability to elicit interaction with a human accompanying the child during the task. Interaction of the children with both partners did not differ apart from the eye-contact. Participants had more eye-contact with the social robot compared to the eye-contact with the human. The conditions did not differ regarding the interaction elicited with the human accompanying the child. En ligne : http://dx.doi.org/10.1007/s10803-015-2556-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278
in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.113-126[article] Children with Autism Spectrum Disorders Make a Fruit Salad with Probo, the Social Robot: An Interaction Study [Texte imprimé et/ou numérique] / Ramona E. SIMUT, Auteur ; Johan VANDERFAEILLIE, Auteur ; Andreea PECA, Auteur ; Greet PERRE, Auteur ; Bram VANDERBORGHT, Auteur . - 2016 . - p.113-126.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.113-126
Mots-clés : Children with ASD Social skills Social robots Interaction Robot assisted therapy Index. décimale : PER Périodiques Résumé : Social robots are thought to be motivating tools in play tasks with children with autism spectrum disorders. Thirty children with autism were included using a repeated measurements design. It was investigated if the children’s interaction with a human differed from the interaction with a social robot during a play task. Also, it was examined if the two conditions differed in their ability to elicit interaction with a human accompanying the child during the task. Interaction of the children with both partners did not differ apart from the eye-contact. Participants had more eye-contact with the social robot compared to the eye-contact with the human. The conditions did not differ regarding the interaction elicited with the human accompanying the child. En ligne : http://dx.doi.org/10.1007/s10803-015-2556-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 Regrouper des jeunes enfants déficients visuels d’école maternelle pour favoriser apprentissages et construction de l’identité sociale / Nathalie LEWI-DUMONT in Nouvelle Revue de l'AIS (La), 46 (Juillet 2009)
[article]
Titre : Regrouper des jeunes enfants déficients visuels d’école maternelle pour favoriser apprentissages et construction de l’identité sociale Type de document : Texte imprimé et/ou numérique Auteurs : Nathalie LEWI-DUMONT, Auteur Année de publication : 2009 Article en page(s) : p. 121-135 Langues : Français (fre) Mots-clés : Braille Cécité Découverte tactile École maternelle Enfant Interaction Littérature Malvoyance Socialisation Index. décimale : PER Périodiques Résumé : À partir de l’observation d’une expérience de regroupement d’élèves malvoyants et aveugles scolarisés en école maternelle, consistant à leur faire découvrir et expérimenter les réalités présentes dans un texte de littérature de jeunesse, l’auteur montre qu’un tel dispositif permet aux enfants de s’approprier à leur rythme des réalités difficilement accessibles sans la vue. Cette expérience les aide en outre, en constituant un groupe de pairs, à se construire une identité dont la déficience visuelle constitue une part. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=158
in Nouvelle Revue de l'AIS (La) > 46 (Juillet 2009) . - p. 121-135[article] Regrouper des jeunes enfants déficients visuels d’école maternelle pour favoriser apprentissages et construction de l’identité sociale [Texte imprimé et/ou numérique] / Nathalie LEWI-DUMONT, Auteur . - 2009 . - p. 121-135.
Langues : Français (fre)
in Nouvelle Revue de l'AIS (La) > 46 (Juillet 2009) . - p. 121-135
Mots-clés : Braille Cécité Découverte tactile École maternelle Enfant Interaction Littérature Malvoyance Socialisation Index. décimale : PER Périodiques Résumé : À partir de l’observation d’une expérience de regroupement d’élèves malvoyants et aveugles scolarisés en école maternelle, consistant à leur faire découvrir et expérimenter les réalités présentes dans un texte de littérature de jeunesse, l’auteur montre qu’un tel dispositif permet aux enfants de s’approprier à leur rythme des réalités difficilement accessibles sans la vue. Cette expérience les aide en outre, en constituant un groupe de pairs, à se construire une identité dont la déficience visuelle constitue une part. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=158 Infant Neural Sensitivity to Dynamic Eye Gaze Relates to Quality of Parent–Infant Interaction at 7-Months in Infants at Risk for Autism / Mayada ELSABBAGH in Journal of Autism and Developmental Disorders, 45-2 (February 2015)
[article]
Titre : Infant Neural Sensitivity to Dynamic Eye Gaze Relates to Quality of Parent–Infant Interaction at 7-Months in Infants at Risk for Autism Type de document : Texte imprimé et/ou numérique Auteurs : Mayada ELSABBAGH, Auteur ; Ruth BRUNO, Auteur ; Ming Wai WAN, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Jonathan GREEN, Auteur Article en page(s) : p.283-291 Langues : Anglais (eng) Mots-clés : Infant Autism Interaction EEG Familial risk Prospective study Index. décimale : PER Périodiques Résumé : Links between brain function measures and quality of parent–child interactions within the early developmental period have been investigated in typical and atypical development. We examined such links in a group of 104 infants with and without a family history for autism in the first year of life. Our findings suggest robust associations between event related potential responses to eye gaze and observed parent–infant interaction measures. In both groups, infants with more positive affect exhibit stronger differentiation to gaze stimuli. This association was observed with the earlier P100 waveform component in the control group but with the later P400 component in infants at-risk. These exploratory findings are critical in paving the way for a better understanding of how infant laboratory measures may relate to overt behavior and how both can be combined in the context of predicting risk or clinical diagnosis in toddlerhood. En ligne : http://dx.doi.org/10.1007/s10803-014-2192-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258
in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.283-291[article] Infant Neural Sensitivity to Dynamic Eye Gaze Relates to Quality of Parent–Infant Interaction at 7-Months in Infants at Risk for Autism [Texte imprimé et/ou numérique] / Mayada ELSABBAGH, Auteur ; Ruth BRUNO, Auteur ; Ming Wai WAN, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Jonathan GREEN, Auteur . - p.283-291.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.283-291
Mots-clés : Infant Autism Interaction EEG Familial risk Prospective study Index. décimale : PER Périodiques Résumé : Links between brain function measures and quality of parent–child interactions within the early developmental period have been investigated in typical and atypical development. We examined such links in a group of 104 infants with and without a family history for autism in the first year of life. Our findings suggest robust associations between event related potential responses to eye gaze and observed parent–infant interaction measures. In both groups, infants with more positive affect exhibit stronger differentiation to gaze stimuli. This association was observed with the earlier P100 waveform component in the control group but with the later P400 component in infants at-risk. These exploratory findings are critical in paving the way for a better understanding of how infant laboratory measures may relate to overt behavior and how both can be combined in the context of predicting risk or clinical diagnosis in toddlerhood. En ligne : http://dx.doi.org/10.1007/s10803-014-2192-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 Research Review: Gene–environment interaction research in youth depression – a systematic review with recommendations for future research / Erin C. DUNN in Journal of Child Psychology and Psychiatry, 52-12 (December 2011)
PermalinkSur les pas de Denise Sadek-Khalil : Rigueur, Liberté et Interaction dans la prise en charge orthophonique / S. VINTER in Rééducation Orthophonique, 258 (Juin 2014)
PermalinkL’apprentissage de la lecture : au-delà du débat des méthodes / S. RAYNAUD in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E., 147 (Octobre 2017)
PermalinkAre there sex differences in interactive associations of environmental exposure to Lead (Pb), Mercury (Hg), and Manganese (Mn) with GST Genes (GSTP1, GSTT1, and GSTM1) in relation to ASD in Jamaican children? / Hiba T. ZWIYA in Research in Autism Spectrum Disorders, 105 (July 2023)
PermalinkAssociation and gene–gene interactions study of reelin signaling pathway related genes with autism in the Han Chinese population / Yidong SHEN in Autism Research, 9-4 (April 2016)
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