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Détail de l'auteur
Auteur Julie B. SCHWEITZER |
Documents disponibles écrits par cet auteur (3)
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Attention-deficit/hyperactivity disorder / Julie B. SCHWEITZER
Titre : Attention-deficit/hyperactivity disorder Type de document : Texte imprimé et/ou numérique Auteurs : Julie B. SCHWEITZER, Auteur ; PAKYUREK,MURAT, Auteur ; J. Faye DIXON, Auteur Année de publication : 2013 Importance : p.29-55 Langues : Anglais (eng) Index. décimale : TRO-F TRO-F - Autres Troubles Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=190 Attention-deficit/hyperactivity disorder [Texte imprimé et/ou numérique] / Julie B. SCHWEITZER, Auteur ; PAKYUREK,MURAT, Auteur ; J. Faye DIXON, Auteur . - 2013 . - p.29-55.
Langues : Anglais (eng)
Index. décimale : TRO-F TRO-F - Autres Troubles Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=190 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire Cognitive training for children and adolescents with fragile X syndrome: a randomized controlled trial of Cogmed / D. HESSL in Journal of Neurodevelopmental Disorders, 11-1 (December 2019)
[article]
Titre : Cognitive training for children and adolescents with fragile X syndrome: a randomized controlled trial of Cogmed Type de document : Texte imprimé et/ou numérique Auteurs : D. HESSL, Auteur ; Julie B. SCHWEITZER, Auteur ; D. V. NGUYEN, Auteur ; Y. A. MCLENNAN, Auteur ; C. JOHNSTON, Auteur ; R. SHICKMAN, Auteur ; Y. CHEN, Auteur Article en page(s) : 4 p. Langues : Anglais (eng) Mots-clés : FMR1 gene Fragile X mental retardation protein Intellectual disability Treatment Working memory Index. décimale : PER Périodiques Résumé : BACKGROUND: Individuals with fragile X syndrome (FXS) typically demonstrate profound executive function (EF) deficits that interfere with learning, socialization, and emotion regulation. We completed the first large, non-pharmacological controlled trial for FXS, designed to evaluate the efficacy of Cogmed, a computer/tablet-based working memory (WM) training program. METHODS: The study was a randomized, blinded, parallel two-arm controlled trial in 100 children and adolescents with FXS (63 male, 37 female; 15.28 +/- 3.36 yrs.). Participants were randomized equally to adaptive (difficulty level adjusted to performance) or non-adaptive (control) Cogmed training. Participants were assessed at home using objective measures of WM (primary outcome) and EF at baseline, following 20-25 caregiver-supported sessions over 5-6 weeks, and at follow-up 3 months after cessation of training. Parents and teachers provided ratings of WM, attention, and EF. RESULTS: The WM composite and selective domains of EF (distractibility, cognitive flexibility), as well as parent- and teacher-reported attention and EF, significantly improved across the full study sample, with many changes maintained at follow-up. However, comparisons of improvement between adaptive and non-adaptive control conditions did not differ, showing that progressively challenging the WM system by expanding span length did not provide added benefit overall. CONCLUSIONS: Further experimental comparisons are needed before Cogmed working memory training can be considered empirically validated for children with FXS, forming the basis of treatment recommendation. However, given that prior studies show no significant changes on these measures in FXS without treatment, that improvements were maintained for 3 months, and that blinded teachers reported improvements in the classroom, the modest benefits seen in both adaptive and non-adaptive groups overall are unlikely to be attributable to placebo or practice effects alone. Future analyses examining inter-individual differences (e.g., baseline capacity, training efficiency, co-morbidity, training environment, characteristics of training aide) may help to link this intervention to outcomes and potential transfer effects. TRIAL REGISTRATION: US National Institutes of Health (ClinicalTrials.gov), NCT02747394 . En ligne : https://dx.doi.org/10.1186/s11689-019-9264-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409
in Journal of Neurodevelopmental Disorders > 11-1 (December 2019) . - 4 p.[article] Cognitive training for children and adolescents with fragile X syndrome: a randomized controlled trial of Cogmed [Texte imprimé et/ou numérique] / D. HESSL, Auteur ; Julie B. SCHWEITZER, Auteur ; D. V. NGUYEN, Auteur ; Y. A. MCLENNAN, Auteur ; C. JOHNSTON, Auteur ; R. SHICKMAN, Auteur ; Y. CHEN, Auteur . - 4 p.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 11-1 (December 2019) . - 4 p.
Mots-clés : FMR1 gene Fragile X mental retardation protein Intellectual disability Treatment Working memory Index. décimale : PER Périodiques Résumé : BACKGROUND: Individuals with fragile X syndrome (FXS) typically demonstrate profound executive function (EF) deficits that interfere with learning, socialization, and emotion regulation. We completed the first large, non-pharmacological controlled trial for FXS, designed to evaluate the efficacy of Cogmed, a computer/tablet-based working memory (WM) training program. METHODS: The study was a randomized, blinded, parallel two-arm controlled trial in 100 children and adolescents with FXS (63 male, 37 female; 15.28 +/- 3.36 yrs.). Participants were randomized equally to adaptive (difficulty level adjusted to performance) or non-adaptive (control) Cogmed training. Participants were assessed at home using objective measures of WM (primary outcome) and EF at baseline, following 20-25 caregiver-supported sessions over 5-6 weeks, and at follow-up 3 months after cessation of training. Parents and teachers provided ratings of WM, attention, and EF. RESULTS: The WM composite and selective domains of EF (distractibility, cognitive flexibility), as well as parent- and teacher-reported attention and EF, significantly improved across the full study sample, with many changes maintained at follow-up. However, comparisons of improvement between adaptive and non-adaptive control conditions did not differ, showing that progressively challenging the WM system by expanding span length did not provide added benefit overall. CONCLUSIONS: Further experimental comparisons are needed before Cogmed working memory training can be considered empirically validated for children with FXS, forming the basis of treatment recommendation. However, given that prior studies show no significant changes on these measures in FXS without treatment, that improvements were maintained for 3 months, and that blinded teachers reported improvements in the classroom, the modest benefits seen in both adaptive and non-adaptive groups overall are unlikely to be attributable to placebo or practice effects alone. Future analyses examining inter-individual differences (e.g., baseline capacity, training efficiency, co-morbidity, training environment, characteristics of training aide) may help to link this intervention to outcomes and potential transfer effects. TRIAL REGISTRATION: US National Institutes of Health (ClinicalTrials.gov), NCT02747394 . En ligne : https://dx.doi.org/10.1186/s11689-019-9264-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409 Inattention and hyperactivity in association with autism spectrum disorders in the CHARGE study / Kristen LYALL in Research in Autism Spectrum Disorders, 35 (March 2017)
[article]
Titre : Inattention and hyperactivity in association with autism spectrum disorders in the CHARGE study Type de document : Texte imprimé et/ou numérique Auteurs : Kristen LYALL, Auteur ; Julie B. SCHWEITZER, Auteur ; Rebecca J. SCHMIDT, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Marjorie SOLOMON, Auteur Article en page(s) : p.1-12 Langues : Anglais (eng) Mots-clés : ASD ADHD Inattention Comorbidity Adaptive functioning Index. décimale : PER Périodiques Résumé : Attention deficits in young children with autism spectrum disorder (ASD) are not well understood. This study sought to determine: 1) the prevalence of ADHD symptoms in young children with ASD, typical development (TD), and developmental delay (DD) and 2) the association between ADHD symptoms and cognitive and behavioral functioning in children with ASD. Method ADHD symptoms, defined according to Aberrant Behavior Checklist (ABC) hyperactivity subscale scores, were compared across children aged 2–5 from a large case-control study with ASD (n = 548), TD (n = 423), and DD (n = 180). Inattention and hyperactivity items within this subscale were also explored. Within the ASD group, linear and logistic regression were used to examine how ADHD symptoms were associated with cognition as assessed by the Mullen Scales of Early Learning and adaptive functioning as assessed by the Vineland Adaptive Behavior Scales. Results Mean hyperactivity subscale scores were lowest in children with TD (mean = 3.19), higher in children with DD (12.3), and highest in children with ASD (18.2; between-group p < 0.001). Among children with ASD, significant associations were observed with higher ADHD symptoms and poorer adaptive and cognitive functioning (adjusted beta for hyperactivity score in association with: Vineland composite = ?5.63, p = 0.0005; Mullen visual reception scale = ?2.94, p = 0.02; for the highest vs. lowest quartile of hyperactivity score, odds of lowest quintile of these scores was approximately doubled). Exploratory analyses highlighted associations with inattention-related items specifically. These results suggest ADHD symptoms may play a key role in the functioning of young children with ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.11.011 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=304
in Research in Autism Spectrum Disorders > 35 (March 2017) . - p.1-12[article] Inattention and hyperactivity in association with autism spectrum disorders in the CHARGE study [Texte imprimé et/ou numérique] / Kristen LYALL, Auteur ; Julie B. SCHWEITZER, Auteur ; Rebecca J. SCHMIDT, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Marjorie SOLOMON, Auteur . - p.1-12.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 35 (March 2017) . - p.1-12
Mots-clés : ASD ADHD Inattention Comorbidity Adaptive functioning Index. décimale : PER Périodiques Résumé : Attention deficits in young children with autism spectrum disorder (ASD) are not well understood. This study sought to determine: 1) the prevalence of ADHD symptoms in young children with ASD, typical development (TD), and developmental delay (DD) and 2) the association between ADHD symptoms and cognitive and behavioral functioning in children with ASD. Method ADHD symptoms, defined according to Aberrant Behavior Checklist (ABC) hyperactivity subscale scores, were compared across children aged 2–5 from a large case-control study with ASD (n = 548), TD (n = 423), and DD (n = 180). Inattention and hyperactivity items within this subscale were also explored. Within the ASD group, linear and logistic regression were used to examine how ADHD symptoms were associated with cognition as assessed by the Mullen Scales of Early Learning and adaptive functioning as assessed by the Vineland Adaptive Behavior Scales. Results Mean hyperactivity subscale scores were lowest in children with TD (mean = 3.19), higher in children with DD (12.3), and highest in children with ASD (18.2; between-group p < 0.001). Among children with ASD, significant associations were observed with higher ADHD symptoms and poorer adaptive and cognitive functioning (adjusted beta for hyperactivity score in association with: Vineland composite = ?5.63, p = 0.0005; Mullen visual reception scale = ?2.94, p = 0.02; for the highest vs. lowest quartile of hyperactivity score, odds of lowest quintile of these scores was approximately doubled). Exploratory analyses highlighted associations with inattention-related items specifically. These results suggest ADHD symptoms may play a key role in the functioning of young children with ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.11.011 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=304