Annual Research Review: Psychosis in children and adolescents - a call to action: a commentary on Kelleher (2025) / James G. SCOTT in Journal of Child Psychology and Psychiatry, 66-4 (April 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-4 (April 2025) . - p.588-591 Titre : Annual Research Review: Psychosis in children and adolescents - a call to action: a commentary on Kelleher (2025) Type de document : Texte imprimé et/ou numérique Auteurs : James G. SCOTT, Auteur Article en page(s) : p.588-591 Langues : Anglais (eng) Mots-clés : Psychosis  children  adolescents  prevention  early intervention Index. décimale : PER Périodiques Résumé : The spectrum of psychosis is highly relevant to child and adolescent mental health. Psychotic symptoms are common in children and adolescents. The onset of psychotic disorders is often preceded by neurodevelopmental problems in early childhood, and some 13% of adolescents attending specialist mental health services will later be diagnosed with a psychotic disorder or bipolar disorder. Although 12% of psychotic disorders and 8% of schizophrenia cases have onset prior to age 18, there is little evidence available to guide the clinical care of young people with early onset psychosis. This commentary summarises the key findings of the annual research review on Psychosis in Children and Adolescents. It highlights the urgent need for clinicians and researchers in child and adolescent mental health to contribute to finding solutions to prevent the onset of psychosis and improve the lives of young people with early onset psychosis and their families. En ligne : https://doi.org/10.1111/jcpp.14135 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=550 [article] Annual Research Review: Psychosis in children and adolescents - a call to action: a commentary on Kelleher (2025) [Texte imprimé et/ou numérique] / James G. SCOTT, Auteur . - p.588-591. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-4 (April 2025) . - p.588-591 Mots-clés : Psychosis  children  adolescents  prevention  early intervention Index. décimale : PER Périodiques Résumé : The spectrum of psychosis is highly relevant to child and adolescent mental health. Psychotic symptoms are common in children and adolescents. The onset of psychotic disorders is often preceded by neurodevelopmental problems in early childhood, and some 13% of adolescents attending specialist mental health services will later be diagnosed with a psychotic disorder or bipolar disorder. Although 12% of psychotic disorders and 8% of schizophrenia cases have onset prior to age 18, there is little evidence available to guide the clinical care of young people with early onset psychosis. This commentary summarises the key findings of the annual research review on Psychosis in Children and Adolescents. It highlights the urgent need for clinicians and researchers in child and adolescent mental health to contribute to finding solutions to prevent the onset of psychosis and improve the lives of young people with early onset psychosis and their families. En ligne : https://doi.org/10.1111/jcpp.14135 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=550

Hypertensive disorders of pregnancy and the risk of offspring depression in childhood: Findings from the Avon Longitudinal Study of Parents and Children / Berihun Assefa DACHEW in Development and Psychopathology, 32-3 (August 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-3 (August 2020) . - p.845-851 Titre : Hypertensive disorders of pregnancy and the risk of offspring depression in childhood: Findings from the Avon Longitudinal Study of Parents and Children Type de document : Texte imprimé et/ou numérique Auteurs : Berihun Assefa DACHEW, Auteur ; James G. SCOTT, Auteur ; Kim S. BETTS, Auteur ; Abdullah MAMUN, Auteur ; Rosa ALATI, Auteur Article en page(s) : p.845-851 Langues : Anglais (eng) Mots-clés : Alspac  childhood depression  hypertensive disorders of pregnancy  offspring Index. décimale : PER Périodiques Résumé : Hypertensive disorders of pregnancy (HDP) may increase the risk of offspring depression in childhood. Low birth weight is also associated with increased risk of mental health problems, including depression. This study sought to investigate (a) whether there is an association between HDP and the risk of depression in childhood and (b) whether low birth weight mediates this association. The current study is based on the Avon Longitudinal Study of Parents and Children (ALSPAC), a prospective, population-based study that has followed a cohort of offspring since their mothers were pregnant (n = 6,739). Depression at the age of 7 years was diagnosed using parent reports via the Development and Well-Being Assessment (DAWBA). Log-binomial regression and mediation analyses were used. Children exposed to HDP were 2.3 times more likely to have a depression diagnosis compared with nonexposed children, adjusted Risk Ratio [RR], 2.31; 95% CI, [1.20, 4.47]. Low birth weight was a weak mediator of this association. Results were adjusted for confounding variables including antenatal depression and anxiety during pregnancy.This study suggests that fetal exposure to maternal hypertensive disorders of pregnancy increased the risk of childhood depression. The study adds to the evidence suggesting that the uterine environment is a critical determinant of neurodevelopmental and psychiatric outcomes. En ligne : http://dx.doi.org/10.1017/s0954579419000944 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429 [article] Hypertensive disorders of pregnancy and the risk of offspring depression in childhood: Findings from the Avon Longitudinal Study of Parents and Children [Texte imprimé et/ou numérique] / Berihun Assefa DACHEW, Auteur ; James G. SCOTT, Auteur ; Kim S. BETTS, Auteur ; Abdullah MAMUN, Auteur ; Rosa ALATI, Auteur . - p.845-851. Langues : Anglais (eng) in Development and Psychopathology > 32-3 (August 2020) . - p.845-851 Mots-clés : Alspac  childhood depression  hypertensive disorders of pregnancy  offspring Index. décimale : PER Périodiques Résumé : Hypertensive disorders of pregnancy (HDP) may increase the risk of offspring depression in childhood. Low birth weight is also associated with increased risk of mental health problems, including depression. This study sought to investigate (a) whether there is an association between HDP and the risk of depression in childhood and (b) whether low birth weight mediates this association. The current study is based on the Avon Longitudinal Study of Parents and Children (ALSPAC), a prospective, population-based study that has followed a cohort of offspring since their mothers were pregnant (n = 6,739). Depression at the age of 7 years was diagnosed using parent reports via the Development and Well-Being Assessment (DAWBA). Log-binomial regression and mediation analyses were used. Children exposed to HDP were 2.3 times more likely to have a depression diagnosis compared with nonexposed children, adjusted Risk Ratio [RR], 2.31; 95% CI, [1.20, 4.47]. Low birth weight was a weak mediator of this association. Results were adjusted for confounding variables including antenatal depression and anxiety during pregnancy.This study suggests that fetal exposure to maternal hypertensive disorders of pregnancy increased the risk of childhood depression. The study adds to the evidence suggesting that the uterine environment is a critical determinant of neurodevelopmental and psychiatric outcomes. En ligne : http://dx.doi.org/10.1017/s0954579419000944 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429

A Relationship Between Early Language Skills and Adult Autistic-Like Traits: Evidence from a Longitudinal Population-Based Study / Rebecca M. ARMSTRONG in Journal of Autism and Developmental Disorders, 47-5 (May 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1478-1489 Titre : A Relationship Between Early Language Skills and Adult Autistic-Like Traits: Evidence from a Longitudinal Population-Based Study Type de document : Texte imprimé et/ou numérique Auteurs : Rebecca M. ARMSTRONG, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; James G. SCOTT, Auteur ; David A. COPLAND, Auteur ; Katie L. MCMAHON, Auteur ; Sophie FLEMING, Auteur ; Wendy ARNOTT, Auteur Article en page(s) : p.1478-1489 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Autistic-like traits  Early language skills  Late talking  Raine Study Index. décimale : PER Périodiques Résumé : The current study examined the relationship between early language ability and autistic-like traits in adulthood, utilising data from 644 participants from a longitudinal study of the general population. Language performance at 2 years was measured with the Language Development Survey (LDS), and at 20 years the participants completed the Autism-Spectrum Quotient (AQ). Vocabulary size at 2 years was negatively associated with Total AQ score, as well as scores on the Communication, and Social Skills subscales. Adults who had been late talkers were also more likely to have ‘high’ scores on the Communication subscale. This is the first study to show an association between early language ability and autistic-like traits in adulthood. En ligne : http://dx.doi.org/10.1007/s10803-016-3014-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305 [article] A Relationship Between Early Language Skills and Adult Autistic-Like Traits: Evidence from a Longitudinal Population-Based Study [Texte imprimé et/ou numérique] / Rebecca M. ARMSTRONG, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; James G. SCOTT, Auteur ; David A. COPLAND, Auteur ; Katie L. MCMAHON, Auteur ; Sophie FLEMING, Auteur ; Wendy ARNOTT, Auteur . - p.1478-1489. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1478-1489 Mots-clés : Autism spectrum disorder  Autistic-like traits  Early language skills  Late talking  Raine Study Index. décimale : PER Périodiques Résumé : The current study examined the relationship between early language ability and autistic-like traits in adulthood, utilising data from 644 participants from a longitudinal study of the general population. Language performance at 2 years was measured with the Language Development Survey (LDS), and at 20 years the participants completed the Autism-Spectrum Quotient (AQ). Vocabulary size at 2 years was negatively associated with Total AQ score, as well as scores on the Communication, and Social Skills subscales. Adults who had been late talkers were also more likely to have ‘high’ scores on the Communication subscale. This is the first study to show an association between early language ability and autistic-like traits in adulthood. En ligne : http://dx.doi.org/10.1007/s10803-016-3014-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305

Research Review: Epidemiological modelling of attention-deficit/hyperactivity disorder and conduct disorder for the Global Burden of Disease Study 2010 / Holly E. ERSKINE in Journal of Child Psychology and Psychiatry, 54-12 (December 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-12 (December 2013) . - p.1263-1274 Titre : Research Review: Epidemiological modelling of attention-deficit/hyperactivity disorder and conduct disorder for the Global Burden of Disease Study 2010 Type de document : Texte imprimé et/ou numérique Auteurs : Holly E. ERSKINE, Auteur ; Alize J. FERRARI, Auteur ; Paul NELSON, Auteur ; Guilherme V. POLANCZYK, Auteur ; Abraham D. FLAXMAN, Auteur ; Theo VOS, Auteur ; Harvey A. WHITEFORD, Auteur ; James G. SCOTT, Auteur Article en page(s) : p.1263-1274 Langues : Anglais (eng) Mots-clés : Global burden of disease study 2010  attention-deficit/hyperactivity disorder  conduct disorder  prevalence  statistical modelling Index. décimale : PER Périodiques Résumé : Background The most recent Global Burden of Disease Study (GBD 2010) is the first to include attention-deficit/hyperactivity disorder (ADHD) and conduct disorder (CD) for burden quantification. We present the epidemiological profiles of ADHD and CD across three time periods for 21 world regions. Methods A systematic review of global epidemiology was conducted for each disorder (based on a literature search of the Medline, PsycInfo and EMBASE databases). A Bayesian metaregression tool was used to derive prevalence estimates by age and sex in three time periods (1990, 2005 and 2010) for 21 world regions including those with little or no data. Prior expert knowledge and covariates were applied to each model to adjust suboptimal data. Final prevalence output for ADHD were adjusted to reflect an equivalent value if studies had measured point prevalence using multiple informants while final prevalence output for CD were adjusted to reflect a value equivalent to CD only. Results Prevalence was pooled for males and females aged 5–19 years with no difference found in global prevalence between the three time periods. Male prevalence of ADHD in 2010 was 2.2% (2.0–2.3) while female prevalence was 0.7% (0.6–0.7). Male prevalence of CD in 2010 was 3.6% (3.3–4.0) while female prevalence was 1.5% (1.4–1.7). ADHD and CD were estimated to be present worldwide with ADHD prevalence showing some regional variation while CD prevalence remained relatively consistent worldwide. Conclusions We present the first prevalence estimates of both ADHD and CD globally and for all world regions. Data were sparse with large parts of the world having no estimates of either disorder. Epidemiological studies are urgently needed in certain parts of the world. Our findings directly informed burden quantification for GBD 2010. As mental disorders gained increased recognition after the first GBD study in 1990, the inclusion of ADHD and CD in GBD 2010 ensures their importance will be recognized alongside other childhood disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12144 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219 [article] Research Review: Epidemiological modelling of attention-deficit/hyperactivity disorder and conduct disorder for the Global Burden of Disease Study 2010 [Texte imprimé et/ou numérique] / Holly E. ERSKINE, Auteur ; Alize J. FERRARI, Auteur ; Paul NELSON, Auteur ; Guilherme V. POLANCZYK, Auteur ; Abraham D. FLAXMAN, Auteur ; Theo VOS, Auteur ; Harvey A. WHITEFORD, Auteur ; James G. SCOTT, Auteur . - p.1263-1274. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-12 (December 2013) . - p.1263-1274 Mots-clés : Global burden of disease study 2010  attention-deficit/hyperactivity disorder  conduct disorder  prevalence  statistical modelling Index. décimale : PER Périodiques Résumé : Background The most recent Global Burden of Disease Study (GBD 2010) is the first to include attention-deficit/hyperactivity disorder (ADHD) and conduct disorder (CD) for burden quantification. We present the epidemiological profiles of ADHD and CD across three time periods for 21 world regions. Methods A systematic review of global epidemiology was conducted for each disorder (based on a literature search of the Medline, PsycInfo and EMBASE databases). A Bayesian metaregression tool was used to derive prevalence estimates by age and sex in three time periods (1990, 2005 and 2010) for 21 world regions including those with little or no data. Prior expert knowledge and covariates were applied to each model to adjust suboptimal data. Final prevalence output for ADHD were adjusted to reflect an equivalent value if studies had measured point prevalence using multiple informants while final prevalence output for CD were adjusted to reflect a value equivalent to CD only. Results Prevalence was pooled for males and females aged 5–19 years with no difference found in global prevalence between the three time periods. Male prevalence of ADHD in 2010 was 2.2% (2.0–2.3) while female prevalence was 0.7% (0.6–0.7). Male prevalence of CD in 2010 was 3.6% (3.3–4.0) while female prevalence was 1.5% (1.4–1.7). ADHD and CD were estimated to be present worldwide with ADHD prevalence showing some regional variation while CD prevalence remained relatively consistent worldwide. Conclusions We present the first prevalence estimates of both ADHD and CD globally and for all world regions. Data were sparse with large parts of the world having no estimates of either disorder. Epidemiological studies are urgently needed in certain parts of the world. Our findings directly informed burden quantification for GBD 2010. As mental disorders gained increased recognition after the first GBD study in 1990, the inclusion of ADHD and CD in GBD 2010 ensures their importance will be recognized alongside other childhood disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12144 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219

Research Review: The role of cytokines in depression in adolescents: a systematic review / Natalie T. MILLS in Journal of Child Psychology and Psychiatry, 54-8 (August 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-8 (August 2013) . - p.816-835 Titre : Research Review: The role of cytokines in depression in adolescents: a systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Natalie T. MILLS, Auteur ; James G. SCOTT, Auteur ; Naomi R. WRAY, Auteur ; Sarah COHEN-WOODS, Auteur ; BERNHARD T. BAUNE, Auteur Article en page(s) : p.816-835 Langues : Anglais (eng) Mots-clés : Cytokines  inflammation  immune system  MDD  cognition  stress Index. décimale : PER Périodiques Résumé : Background While cytokines have been implicated in the pathophysiology of depression in adults, the potential role in younger age groups such as adolescents is less clear. This article therefore reviews the literature (a) to explore the relationship between cytokines and depression in adolescents, and (b) to examine how cytokines may be related to adolescent depression in the context of other neurobiological theories of depression. Method A systematic review of the scientific literature on the subject was conducted in February 2013, searching the Web of Knowledge, PubMed (Medline), PsycInfo and Cochrane electronic databases. Results Eighteen studies were identified measuring both depression or depressive symptoms and cytokines or immune markers in adolescents. Adolescents with depression show age-specific characteristics of the immune and inflammatory system, specifically in NK cell activity and in pro-inflammatory cytokines (such as IL-1? and TNF-?). In addition, the role of cytokines in adolescent depression is influenced by neurodevelopment, hormonal changes, stress and trauma. Conclusions There may be differences in the neurobiology of adolescent major depressive disorder (MDD) compared with adult MDD. Increased understanding of the role of cytokines in adolescent MDD may lead to improved outcomes in the treatment of adolescent depression. En ligne : http://dx.doi.org/10.1111/jcpp.12080 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=210 [article] Research Review: The role of cytokines in depression in adolescents: a systematic review [Texte imprimé et/ou numérique] / Natalie T. MILLS, Auteur ; James G. SCOTT, Auteur ; Naomi R. WRAY, Auteur ; Sarah COHEN-WOODS, Auteur ; BERNHARD T. BAUNE, Auteur . - p.816-835. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-8 (August 2013) . - p.816-835 Mots-clés : Cytokines  inflammation  immune system  MDD  cognition  stress Index. décimale : PER Périodiques Résumé : Background While cytokines have been implicated in the pathophysiology of depression in adults, the potential role in younger age groups such as adolescents is less clear. This article therefore reviews the literature (a) to explore the relationship between cytokines and depression in adolescents, and (b) to examine how cytokines may be related to adolescent depression in the context of other neurobiological theories of depression. Method A systematic review of the scientific literature on the subject was conducted in February 2013, searching the Web of Knowledge, PubMed (Medline), PsycInfo and Cochrane electronic databases. Results Eighteen studies were identified measuring both depression or depressive symptoms and cytokines or immune markers in adolescents. Adolescents with depression show age-specific characteristics of the immune and inflammatory system, specifically in NK cell activity and in pro-inflammatory cytokines (such as IL-1? and TNF-?). In addition, the role of cytokines in adolescent depression is influenced by neurodevelopment, hormonal changes, stress and trauma. Conclusions There may be differences in the neurobiology of adolescent major depressive disorder (MDD) compared with adult MDD. Increased understanding of the role of cytokines in adolescent MDD may lead to improved outcomes in the treatment of adolescent depression. En ligne : http://dx.doi.org/10.1111/jcpp.12080 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=210

The global burden of conduct disorder and attention-deficit/hyperactivity disorder in 2010 / Holly E. ERSKINE in Journal of Child Psychology and Psychiatry, 55-4 (April 2014)  

Permalink

---

1 (1 - 6 / 6)