Dépouillements

Uncertainty, sensory processing, and stress in autistic children during the COVID-19 pandemic / Garrett CARDON in Research in Autism Spectrum Disorders, 106 (August 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 106 (August 2023) . - 102202 Titre : Uncertainty, sensory processing, and stress in autistic children during the COVID-19 pandemic Type de document : Texte imprimé et/ou numérique Auteurs : Garrett CARDON, Auteur ; Mollie BRADLEY, Auteur Année de publication : 2023 Article en page(s) : 102202 Langues : Anglais (eng) Mots-clés : Autism  Sensory processing  Intolerance of uncertainty  COVID-19  Routine disturbance  Stress Index. décimale : PER Périodiques Résumé : Background COVID-19 increased uncertainty for most and was especially disruptive to autistic people and their families, due in part to tendencies toward intolerance for uncertainty across this population. As such, COVID presented a natural experiment of uncertainty and its correlates in autism. Previous reports have shown associations between intolerance of uncertainty, sensory difficulty, and stress. Aims We investigated changes in sensory difficulties and stress associated with COVID-related increases in uncertainty. Methods and procedures Primary caregivers of 47 autistic children (ages 6-15) completed online surveys containing questions about demographics, experiences, and supports received during the pandemic. Additionally, caregivers filled out measures of intolerance of uncertainty and sensory processing for both pre- and during-COVID conditions. Outcomes and results Eighty nine percent of children had significant sensory difficulties before the pandemic. This group showed significant increases in sensory difficulties and intolerance of uncertainty during the pandemic. These changes were significantly correlated with each other, suggesting that as uncertainty increased so did sensory difficulties. Disruption to routine was also significantly correlated with sensory differences and child, household, and parent stress. Conclusions and implications Our findings add to fundamental understanding of the relationship between uncertainty, sensory processing, and stress by leveraging a natural experiment in increased uncertainty. These results have the potential to contribute to improved supports for autistic individuals in clinical, educational, home, and other settings. En ligne : https://doi.org/10.1016/j.rasd.2023.102202 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509 [article] Uncertainty, sensory processing, and stress in autistic children during the COVID-19 pandemic [Texte imprimé et/ou numérique] / Garrett CARDON, Auteur ; Mollie BRADLEY, Auteur . - 2023 . - 102202. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 106 (August 2023) . - 102202 Mots-clés : Autism  Sensory processing  Intolerance of uncertainty  COVID-19  Routine disturbance  Stress Index. décimale : PER Périodiques Résumé : Background COVID-19 increased uncertainty for most and was especially disruptive to autistic people and their families, due in part to tendencies toward intolerance for uncertainty across this population. As such, COVID presented a natural experiment of uncertainty and its correlates in autism. Previous reports have shown associations between intolerance of uncertainty, sensory difficulty, and stress. Aims We investigated changes in sensory difficulties and stress associated with COVID-related increases in uncertainty. Methods and procedures Primary caregivers of 47 autistic children (ages 6-15) completed online surveys containing questions about demographics, experiences, and supports received during the pandemic. Additionally, caregivers filled out measures of intolerance of uncertainty and sensory processing for both pre- and during-COVID conditions. Outcomes and results Eighty nine percent of children had significant sensory difficulties before the pandemic. This group showed significant increases in sensory difficulties and intolerance of uncertainty during the pandemic. These changes were significantly correlated with each other, suggesting that as uncertainty increased so did sensory difficulties. Disruption to routine was also significantly correlated with sensory differences and child, household, and parent stress. Conclusions and implications Our findings add to fundamental understanding of the relationship between uncertainty, sensory processing, and stress by leveraging a natural experiment in increased uncertainty. These results have the potential to contribute to improved supports for autistic individuals in clinical, educational, home, and other settings. En ligne : https://doi.org/10.1016/j.rasd.2023.102202 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509

Perceived negative impact of caregiving demands in parents of individuals with autism spectrum disorders from 9 to 25 years of age / Kourtney CHRISTOPHER in Research in Autism Spectrum Disorders, 106 (August 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 106 (August 2023) . - 102203 Titre : Perceived negative impact of caregiving demands in parents of individuals with autism spectrum disorders from 9 to 25 years of age Type de document : Texte imprimé et/ou numérique Auteurs : Kourtney CHRISTOPHER, Auteur ; Maira TAFOLLA, Auteur ; Kyle STERRETT, Auteur ; Rebecca ELIAS, Auteur ; Catherine LORD, Auteur Année de publication : 2023 Article en page(s) : 102203 Langues : Anglais (eng) Mots-clés : Perceived negative impact of caregiving  Caregivers  ASD  Adolescence  Adulthood  Longitudinal Index. décimale : PER Périodiques Résumé : Background Caregivers of autistic individuals often report higher levels of perceived negative impact of caregiving. We know very little about the trajectories of caregivers perceived negative impact related to caregiving demands over time in autism. Method The aim of this study was to identify trajectories of perceived negative impact related to parenting of caregivers of autistic individuals and other developmental delays from childhood through emerging adulthood (n = 209). We also explored the factors that predict trajectories of caregiver perceived negative impact including the characteristics of the autistic individuals at age 9 (i.e., social affect, restricted and repetitive behaviors, irritability, hyperactivity, daily living skills and cognitive ability) and caregivers' race, education, social support, and study site. Results Latent class growth modelling yielded three negative impact of caregiving classes: (1) a low impact class that decreased over time (n = 68, 32.54 %), (2) a medium impact class that increased in negative impact during adolescence and decreased in emerging adulthood (n = 98, 46.98 %), and (3) a high impact class that decreased over time (n = 43, 20.57 %). Across all classes, reductions in negative impact of caregiving over time were reported in emerging adulthood, but the high and medium impact groups were still elevated in comparison to the low impact class at the last timepoint. Caregivers of children with less irritability and parent-reported restricted and repetitive behaviors were more likely to belong to the low negative impact group. Caregivers who were African American, had lower educational attainment and those with social support were more likely to belong to the low negative impact group. Conclusions These findings highlight the importance of continued support for caregivers of autistic individuals over time. The influence of race and education on levels of caregiver perceived negative impact of caregiving are discussed further. En ligne : https://doi.org/10.1016/j.rasd.2023.102203 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509 [article] Perceived negative impact of caregiving demands in parents of individuals with autism spectrum disorders from 9 to 25 years of age [Texte imprimé et/ou numérique] / Kourtney CHRISTOPHER, Auteur ; Maira TAFOLLA, Auteur ; Kyle STERRETT, Auteur ; Rebecca ELIAS, Auteur ; Catherine LORD, Auteur . - 2023 . - 102203. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 106 (August 2023) . - 102203 Mots-clés : Perceived negative impact of caregiving  Caregivers  ASD  Adolescence  Adulthood  Longitudinal Index. décimale : PER Périodiques Résumé : Background Caregivers of autistic individuals often report higher levels of perceived negative impact of caregiving. We know very little about the trajectories of caregivers perceived negative impact related to caregiving demands over time in autism. Method The aim of this study was to identify trajectories of perceived negative impact related to parenting of caregivers of autistic individuals and other developmental delays from childhood through emerging adulthood (n = 209). We also explored the factors that predict trajectories of caregiver perceived negative impact including the characteristics of the autistic individuals at age 9 (i.e., social affect, restricted and repetitive behaviors, irritability, hyperactivity, daily living skills and cognitive ability) and caregivers' race, education, social support, and study site. Results Latent class growth modelling yielded three negative impact of caregiving classes: (1) a low impact class that decreased over time (n = 68, 32.54 %), (2) a medium impact class that increased in negative impact during adolescence and decreased in emerging adulthood (n = 98, 46.98 %), and (3) a high impact class that decreased over time (n = 43, 20.57 %). Across all classes, reductions in negative impact of caregiving over time were reported in emerging adulthood, but the high and medium impact groups were still elevated in comparison to the low impact class at the last timepoint. Caregivers of children with less irritability and parent-reported restricted and repetitive behaviors were more likely to belong to the low negative impact group. Caregivers who were African American, had lower educational attainment and those with social support were more likely to belong to the low negative impact group. Conclusions These findings highlight the importance of continued support for caregivers of autistic individuals over time. The influence of race and education on levels of caregiver perceived negative impact of caregiving are discussed further. En ligne : https://doi.org/10.1016/j.rasd.2023.102203 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509

Measuring dyspraxia in autism using a five-minute praxis exam / Ashley DE MARCHENA in Research in Autism Spectrum Disorders, 106 (August 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 106 (August 2023) . - 102200 Titre : Measuring dyspraxia in autism using a five-minute praxis exam Type de document : Texte imprimé et/ou numérique Auteurs : Ashley DE MARCHENA, Auteur ; Casey J. ZAMPELLA, Auteur ; Zachary DRAVIS, Auteur ; Juhi PANDEY, Auteur ; Stewart MOSTOFSKY, Auteur ; Robert T. SCHULTZ, Auteur Année de publication : 2023 Article en page(s) : 102200 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Praxis  Motor skills  Nonverbal communication  Imitation  Adaptive behavior skills Index. décimale : PER Périodiques Résumé : Background Difficulties with praxis, the ability to perform learned skilled movements, have been robustly demonstrated in autism spectrum disorder (autism). However, praxis assessment is not routinely included in autism characterization batteries, in part because it is traditionally time consuming to administer and score. We test whether dyspraxia in autism can be captured with a brief measure. Method Youth with autism (n = 41) and matched typically developing controls (n = 32), aged 8-16 years, completed a 5-min praxis battery. The 19-item battery included four subtests: gesture to command, tool use, familiar imitation, and meaningless imitation. Video recordings were coded for error types and compared to participant characterization variables. Results Consistent with research using a lengthy battery, autistic youth made more errors overall, with a large effect size. Groups demonstrated similar distributions of error types, suggesting that dyspraxia in autism is not limited to a particular error form. In the autism group, praxis was associated with adaptive functioning, but not autism traits. Conclusions A shortened battery is sufficiently sensitive to praxis differences between autistic and typically developing youth, increasing the feasibility of including praxis within clinical assessments or larger research batteries aimed at testing relationships with downstream skills. En ligne : https://doi.org/10.1016/j.rasd.2023.102200 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509 [article] Measuring dyspraxia in autism using a five-minute praxis exam [Texte imprimé et/ou numérique] / Ashley DE MARCHENA, Auteur ; Casey J. ZAMPELLA, Auteur ; Zachary DRAVIS, Auteur ; Juhi PANDEY, Auteur ; Stewart MOSTOFSKY, Auteur ; Robert T. SCHULTZ, Auteur . - 2023 . - 102200. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 106 (August 2023) . - 102200 Mots-clés : Autism spectrum disorder  Praxis  Motor skills  Nonverbal communication  Imitation  Adaptive behavior skills Index. décimale : PER Périodiques Résumé : Background Difficulties with praxis, the ability to perform learned skilled movements, have been robustly demonstrated in autism spectrum disorder (autism). However, praxis assessment is not routinely included in autism characterization batteries, in part because it is traditionally time consuming to administer and score. We test whether dyspraxia in autism can be captured with a brief measure. Method Youth with autism (n = 41) and matched typically developing controls (n = 32), aged 8-16 years, completed a 5-min praxis battery. The 19-item battery included four subtests: gesture to command, tool use, familiar imitation, and meaningless imitation. Video recordings were coded for error types and compared to participant characterization variables. Results Consistent with research using a lengthy battery, autistic youth made more errors overall, with a large effect size. Groups demonstrated similar distributions of error types, suggesting that dyspraxia in autism is not limited to a particular error form. In the autism group, praxis was associated with adaptive functioning, but not autism traits. Conclusions A shortened battery is sufficiently sensitive to praxis differences between autistic and typically developing youth, increasing the feasibility of including praxis within clinical assessments or larger research batteries aimed at testing relationships with downstream skills. En ligne : https://doi.org/10.1016/j.rasd.2023.102200 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509

Psychometric characteristics of the AQ-Adolescent in autistic and non-autistic adolescents / Marieke DE VRIES in Research in Autism Spectrum Disorders, 106 (August 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 106 (August 2023) . - 102201 Titre : Psychometric characteristics of the AQ-Adolescent in autistic and non-autistic adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Marieke DE VRIES, Auteur ; Sander BEGEER, Auteur ; Hilde M. GEURTS, Auteur Année de publication : 2023 Article en page(s) : 102201 Langues : Anglais (eng) Mots-clés : Autism-Spectrum Quotient  Adolescent  Factor structure  Clinical utility Index. décimale : PER Périodiques Résumé : The Autism Spectrum Quotient (AQ) measures autistic traits in children and adults. The adolescent version of the AQ is understudied. We analyzed the factor structure, informant- and sex differences, and clinical utility of the AQ adolescent in 1) parent reports from adolescents in the general population (GenPop; AQ50; N = 465), parent reports from autistic adolescents (Netherlands Autism Register, NAR; AQ28 [Hoekstra et al., 2011]; N = 284), and parent- and self-reports of autistic and non-autistic adolescents (MATCH; AQ50; N = 84). The tested AQ-Adult factor models (Hoekstra et al., 2011; Murray, Allison et al., 2017; Murray, McKenzie et al., 2017; Russell-Smith et al., 2011), showed an acceptable fit in the GenPop sample, and the bi-factor AQ28-Hoekstra (Murray et al., 2011) fitted the NAR sample acceptably. On the AQ28-Hoekstra, autistic adolescents scored lower whereas non-autistic adolescents scored higher than their parents (MATCH), and males scored higher than females on several factors (GenPop, NAR). Moreover, this factor model appeared invariant among autistic and non-autistic groups. Two cut-off scores were evaluated with ROC analyses for parent reports. Given the informant differences, these cannot be applied to self-reports. In conclusion, the AQ28-Hoekstra reliably measures autistic traits in adolescents with and without autism. Combining parent and self-report seems most informative. En ligne : https://doi.org/10.1016/j.rasd.2023.102201 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509 [article] Psychometric characteristics of the AQ-Adolescent in autistic and non-autistic adolescents [Texte imprimé et/ou numérique] / Marieke DE VRIES, Auteur ; Sander BEGEER, Auteur ; Hilde M. GEURTS, Auteur . - 2023 . - 102201. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 106 (August 2023) . - 102201 Mots-clés : Autism-Spectrum Quotient  Adolescent  Factor structure  Clinical utility Index. décimale : PER Périodiques Résumé : The Autism Spectrum Quotient (AQ) measures autistic traits in children and adults. The adolescent version of the AQ is understudied. We analyzed the factor structure, informant- and sex differences, and clinical utility of the AQ adolescent in 1) parent reports from adolescents in the general population (GenPop; AQ50; N = 465), parent reports from autistic adolescents (Netherlands Autism Register, NAR; AQ28 [Hoekstra et al., 2011]; N = 284), and parent- and self-reports of autistic and non-autistic adolescents (MATCH; AQ50; N = 84). The tested AQ-Adult factor models (Hoekstra et al., 2011; Murray, Allison et al., 2017; Murray, McKenzie et al., 2017; Russell-Smith et al., 2011), showed an acceptable fit in the GenPop sample, and the bi-factor AQ28-Hoekstra (Murray et al., 2011) fitted the NAR sample acceptably. On the AQ28-Hoekstra, autistic adolescents scored lower whereas non-autistic adolescents scored higher than their parents (MATCH), and males scored higher than females on several factors (GenPop, NAR). Moreover, this factor model appeared invariant among autistic and non-autistic groups. Two cut-off scores were evaluated with ROC analyses for parent reports. Given the informant differences, these cannot be applied to self-reports. In conclusion, the AQ28-Hoekstra reliably measures autistic traits in adolescents with and without autism. Combining parent and self-report seems most informative. En ligne : https://doi.org/10.1016/j.rasd.2023.102201 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509

Towards reproducible and respectful autism research: Combining open and participatory autism research practices / Hannah HOBSON in Research in Autism Spectrum Disorders, 106 (August 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 106 (August 2023) . - 102196 Titre : Towards reproducible and respectful autism research: Combining open and participatory autism research practices Type de document : Texte imprimé et/ou numérique Auteurs : Hannah HOBSON, Auteur ; Audrey LINDEN, Auteur ; Laura CRANE, Auteur ; Tamara KALANDADZE, Auteur Année de publication : 2023 Article en page(s) : 102196 Langues : Anglais (eng) Mots-clés : Autism  Open science  Open research  Participatory research  Co-production Index. décimale : PER Périodiques Résumé : Background Open research broadly refers to a set of practices that aim to increase transparency, rigor, reproducibility and inclusivity of research. Participatory research refers to incorporating the views and sharing power with the autism community to decide what research gets done, how it is done and how it is implemented. There is growing interest in both open and participatory practices in autism research. To date, however, these practices have tended to be considered separately. Method In this paper, we outline the value of both open and participatory approaches to the autism research field, highlighting key points of overlap. Results We propose three core principles underpinning open and participatory autism research: (1) the need for adequate expertise and infrastructure to facilitate high quality research, (2) the need for a greater degree of accessibility at all stages of the research process, and (3) the need to foster trusting relationships between the autistic and research communities. Conclusion There are various challenges and opportunities of adopting open and participatory principles in autism research. We hope our principles support researchers to embed these approaches more fully within their work. En ligne : https://doi.org/10.1016/j.rasd.2023.102196 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509 [article] Towards reproducible and respectful autism research: Combining open and participatory autism research practices [Texte imprimé et/ou numérique] / Hannah HOBSON, Auteur ; Audrey LINDEN, Auteur ; Laura CRANE, Auteur ; Tamara KALANDADZE, Auteur . - 2023 . - 102196. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 106 (August 2023) . - 102196 Mots-clés : Autism  Open science  Open research  Participatory research  Co-production Index. décimale : PER Périodiques Résumé : Background Open research broadly refers to a set of practices that aim to increase transparency, rigor, reproducibility and inclusivity of research. Participatory research refers to incorporating the views and sharing power with the autism community to decide what research gets done, how it is done and how it is implemented. There is growing interest in both open and participatory practices in autism research. To date, however, these practices have tended to be considered separately. Method In this paper, we outline the value of both open and participatory approaches to the autism research field, highlighting key points of overlap. Results We propose three core principles underpinning open and participatory autism research: (1) the need for adequate expertise and infrastructure to facilitate high quality research, (2) the need for a greater degree of accessibility at all stages of the research process, and (3) the need to foster trusting relationships between the autistic and research communities. Conclusion There are various challenges and opportunities of adopting open and participatory principles in autism research. We hope our principles support researchers to embed these approaches more fully within their work. En ligne : https://doi.org/10.1016/j.rasd.2023.102196 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509

Exploring bidirectional relationships: Child sleep duration, child behavior problems, and parenting stress in families of children with autism spectrum disorder / Brooke K. IWAMOTO in Research in Autism Spectrum Disorders, 106 (August 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 106 (August 2023) . - 102197 Titre : Exploring bidirectional relationships: Child sleep duration, child behavior problems, and parenting stress in families of children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Brooke K. IWAMOTO, Auteur ; Cameron L. NEECE, Auteur ; Aarti NAIR, Auteur ; Nicholas J. ROCKWOOD, Auteur ; Rachel M. FENNING, Auteur ; Megan L. KRANTZ, Auteur ; Tori R. VAN DYK, Auteur Année de publication : 2023 Article en page(s) : 102197 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Behavior problems  Sleep  Parenting  Stress Index. décimale : PER Périodiques Résumé : Background Youth with Autism Spectrum Disorder (ASD) are at-risk for sleep and behavior problems, and their parents are at-risk for high stress. Child sleep duration, behavior problems, and parenting stress are interrelated; however, directionality of these associations is unclear and research including youth with ASD is lacking. Using a day-to-day, within-person design, this study explores the directionality of these relationships in families of children with ASD. Method Twenty-six children (ages 3-5, 73.1 % male, 65.4 % Hispanic/Latino) with ASD and their mothers participated in a 14-day study. Child sleep duration (parent-report and actigraphy), behavior problems, and parenting stress were measured daily. Constructs were decomposed into their within- and between-person components and analyzed with random intercept cross-lagged panel models. Results While between-person relationships were directionally expected in that shorter sleep, more behavior problems, and greater parenting stress were associated, within-person relationships were complicated. Better-than-average child behavior was associated with less next-day parenting stress, yet more parenting stress than average was associated with better next-day child behavior. As expected, longer-than-average child sleep was associated with less next-day parenting stress, while greater child behavior problems were associated with less sleep that night. Conclusions Understanding the directionality of associations between child and parent factors allows for the optimization of interventions to improve the quality of life for families of children with ASD. Interventions that target child behavior and/or help parents manage stress while maintaining effective parenting strategies for sleep and behavior may be useful. En ligne : https://doi.org/10.1016/j.rasd.2023.102197 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509 [article] Exploring bidirectional relationships: Child sleep duration, child behavior problems, and parenting stress in families of children with autism spectrum disorder [Texte imprimé et/ou numérique] / Brooke K. IWAMOTO, Auteur ; Cameron L. NEECE, Auteur ; Aarti NAIR, Auteur ; Nicholas J. ROCKWOOD, Auteur ; Rachel M. FENNING, Auteur ; Megan L. KRANTZ, Auteur ; Tori R. VAN DYK, Auteur . - 2023 . - 102197. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 106 (August 2023) . - 102197 Mots-clés : Autism spectrum disorder  Behavior problems  Sleep  Parenting  Stress Index. décimale : PER Périodiques Résumé : Background Youth with Autism Spectrum Disorder (ASD) are at-risk for sleep and behavior problems, and their parents are at-risk for high stress. Child sleep duration, behavior problems, and parenting stress are interrelated; however, directionality of these associations is unclear and research including youth with ASD is lacking. Using a day-to-day, within-person design, this study explores the directionality of these relationships in families of children with ASD. Method Twenty-six children (ages 3-5, 73.1 % male, 65.4 % Hispanic/Latino) with ASD and their mothers participated in a 14-day study. Child sleep duration (parent-report and actigraphy), behavior problems, and parenting stress were measured daily. Constructs were decomposed into their within- and between-person components and analyzed with random intercept cross-lagged panel models. Results While between-person relationships were directionally expected in that shorter sleep, more behavior problems, and greater parenting stress were associated, within-person relationships were complicated. Better-than-average child behavior was associated with less next-day parenting stress, yet more parenting stress than average was associated with better next-day child behavior. As expected, longer-than-average child sleep was associated with less next-day parenting stress, while greater child behavior problems were associated with less sleep that night. Conclusions Understanding the directionality of associations between child and parent factors allows for the optimization of interventions to improve the quality of life for families of children with ASD. Interventions that target child behavior and/or help parents manage stress while maintaining effective parenting strategies for sleep and behavior may be useful. En ligne : https://doi.org/10.1016/j.rasd.2023.102197 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509

Exploring experiences of vaccine-related and alternative treatments for individuals with autism: A qualitative study / Kim M. JONKMAN in Research in Autism Spectrum Disorders, 106 (August 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 106 (August 2023) . - 102204 Titre : Exploring experiences of vaccine-related and alternative treatments for individuals with autism: A qualitative study Type de document : Texte imprimé et/ou numérique Auteurs : Kim M. JONKMAN, Auteur ; Maria LIVANOU, Auteur ; Manna A. ALMA, Auteur ; Lotte BENARD, Auteur ; Sander BEGEER, Auteur ; Elisa BACK, Auteur Année de publication : 2023 Article en page(s) : 102204 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Complementary and alternative medicine  Complementary health approaches  Qualitative study Index. décimale : PER Périodiques Résumé : Some alternative treatments wrongly suggest that routine childhood vaccines cause autism resulting in vaccine skepticism and false claims about curing autism. In the present study we explore the experiences of vaccine-related and alternative treatments of autistic individuals. Semi-structured interviews were conducted with autistic adults (n = 3), parents of autistic children (n = 5) and parents of autistic adults (n = 5). Thematic analysis showed five themes: (1) reasons for choosing alternative treatment, (2) treatment content, (3) experiences with alternative care, (4) outcomes of the vaccine-related treatment and (5) future directions for treating autism. Both positive (holistic approach, time and attention) and negative aspects (false claims about vaccines and curability of autism) were found. Improved support and guidelines could reduce ineffective and harmful alternative treatments for autism. En ligne : https://doi.org/10.1016/j.rasd.2023.102204 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509 [article] Exploring experiences of vaccine-related and alternative treatments for individuals with autism: A qualitative study [Texte imprimé et/ou numérique] / Kim M. JONKMAN, Auteur ; Maria LIVANOU, Auteur ; Manna A. ALMA, Auteur ; Lotte BENARD, Auteur ; Sander BEGEER, Auteur ; Elisa BACK, Auteur . - 2023 . - 102204. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 106 (August 2023) . - 102204 Mots-clés : Autism spectrum disorder  Complementary and alternative medicine  Complementary health approaches  Qualitative study Index. décimale : PER Périodiques Résumé : Some alternative treatments wrongly suggest that routine childhood vaccines cause autism resulting in vaccine skepticism and false claims about curing autism. In the present study we explore the experiences of vaccine-related and alternative treatments of autistic individuals. Semi-structured interviews were conducted with autistic adults (n = 3), parents of autistic children (n = 5) and parents of autistic adults (n = 5). Thematic analysis showed five themes: (1) reasons for choosing alternative treatment, (2) treatment content, (3) experiences with alternative care, (4) outcomes of the vaccine-related treatment and (5) future directions for treating autism. Both positive (holistic approach, time and attention) and negative aspects (false claims about vaccines and curability of autism) were found. Improved support and guidelines could reduce ineffective and harmful alternative treatments for autism. En ligne : https://doi.org/10.1016/j.rasd.2023.102204 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509

Preliminary evaluation of potential urinary organic acid biomarkers with mass spectrometry in children with autism spectrum disorder / Erdim SERTOGLU in Research in Autism Spectrum Disorders, 106 (August 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 106 (August 2023) . - 102198 Titre : Preliminary evaluation of potential urinary organic acid biomarkers with mass spectrometry in children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Erdim SERTOGLU, Auteur ; Ahmet Rifat BALIK, Auteur ; Umut Goktan DUMAN, Auteur ; Murat Emrah MAVIS, Auteur ; Mutluay ARSLAN, Auteur ; Yilmaz YILDIZ, Auteur ; Janserey BATU, Auteur ; Asburce OLGAC, Auteur ; Özlem HEKIM, Auteur Année de publication : 2023 Article en page(s) : 102198 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Urinary organic acids  Mass spectrometry  Metabolomics Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting brain functions in which qualitative and quantitative problems in communication and behavior are accompanied by restricted interest and repetitive behaviors. There is no laboratory method, or a special test used to diagnose ASD. Here we aimed to report the analysis of the urinary metabolic signatures of ASD patients and healthy subjects to compare the significant changes in the main components of metabolic pathways. Method A total of 85 male subjects, 42 patients and 43 controls, aged 3-18 years, were included in the study. Urine organic acid levels were analyzed by both GC-MS and LC-MS/MS and the results were recorded. The results obtained were statistically evaluated between the patient and control groups. Results Certain metabolites involved in branched-chain amino acid metabolism, aromatic amino acid metabolism, tricarboxylic acid cycle, and glycolysis metabolites were found to be significantly reduced in the patient group compared to controls. Conclusions Our study is the first in the literature in terms of evaluating both GC-MS and LC-MS/MS together and revealing the general map of metabolism. In addition to revealing some new metabolites in ASD patients, it is also important in terms of summarizing which main pathways these metabolites play a role in. Today, with the widespread use of devices that measure with high sensitivity and provide the opportunity to evaluate many analytes at the same time, it will be possible to reveal the pathology of diseases more accurately such as ASD whose etiopathogenesis has not been fully revealed. En ligne : https://doi.org/10.1016/j.rasd.2023.102198 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509 [article] Preliminary evaluation of potential urinary organic acid biomarkers with mass spectrometry in children with autism spectrum disorder [Texte imprimé et/ou numérique] / Erdim SERTOGLU, Auteur ; Ahmet Rifat BALIK, Auteur ; Umut Goktan DUMAN, Auteur ; Murat Emrah MAVIS, Auteur ; Mutluay ARSLAN, Auteur ; Yilmaz YILDIZ, Auteur ; Janserey BATU, Auteur ; Asburce OLGAC, Auteur ; Özlem HEKIM, Auteur . - 2023 . - 102198. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 106 (August 2023) . - 102198 Mots-clés : Autism spectrum disorder  Urinary organic acids  Mass spectrometry  Metabolomics Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting brain functions in which qualitative and quantitative problems in communication and behavior are accompanied by restricted interest and repetitive behaviors. There is no laboratory method, or a special test used to diagnose ASD. Here we aimed to report the analysis of the urinary metabolic signatures of ASD patients and healthy subjects to compare the significant changes in the main components of metabolic pathways. Method A total of 85 male subjects, 42 patients and 43 controls, aged 3-18 years, were included in the study. Urine organic acid levels were analyzed by both GC-MS and LC-MS/MS and the results were recorded. The results obtained were statistically evaluated between the patient and control groups. Results Certain metabolites involved in branched-chain amino acid metabolism, aromatic amino acid metabolism, tricarboxylic acid cycle, and glycolysis metabolites were found to be significantly reduced in the patient group compared to controls. Conclusions Our study is the first in the literature in terms of evaluating both GC-MS and LC-MS/MS together and revealing the general map of metabolism. In addition to revealing some new metabolites in ASD patients, it is also important in terms of summarizing which main pathways these metabolites play a role in. Today, with the widespread use of devices that measure with high sensitivity and provide the opportunity to evaluate many analytes at the same time, it will be possible to reveal the pathology of diseases more accurately such as ASD whose etiopathogenesis has not been fully revealed. En ligne : https://doi.org/10.1016/j.rasd.2023.102198 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509

Goal-directed action anticipation and prediction error processing in children with autism spectrum disorders: An eye-movement study / Cheng-Hui TAN in Research in Autism Spectrum Disorders, 106 (August 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 106 (August 2023) . - 102199 Titre : Goal-directed action anticipation and prediction error processing in children with autism spectrum disorders: An eye-movement study Type de document : Texte imprimé et/ou numérique Auteurs : Cheng-Hui TAN, Auteur ; Qi-Qi XING, Auteur ; Yuan ZHAO, Auteur ; Bo-Hai SONG, Auteur ; Chuan-Lin ZHU, Auteur ; Jun-Jie QIU, Auteur ; Mu-Ye HE, Auteur ; Dian-Zhi LIU, Auteur Année de publication : 2023 Article en page(s) : 102199 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Goal-directed action anticipation  Prediction error  Eye-movement Index. décimale : PER Périodiques Résumé : Background Differences in predictive ability have been proposed as a possible explanation for the core symptoms of autism spectrum disorder (ASD). This study aimed to investigate potential differences in prior knowledge acquisition and application for goal-directed anticipation in children with ASD. Method The study included 22 children with ASD and 19 typically developing (TD) children between the ages of 5-10 years. Two eye-tracking phases were used to examine the formation of goal-directed action anticipations and the processing of action prediction errors. In the action anticipation formation phase, participants were asked to observe goal-directed actions repeatedly to examine prior knowledge acquisition about agent-goal association. In the action anticipation violation phase, the goals of actions were changed to examine the application of previously acquired knowledge. Results Children with ASD required more trials to form goal-directed anticipations than TD children. Furthermore, prior knowledge acquisition was characterized by variability and instability in children with ASD. During the action anticipation violation phase, children with ASD exhibited lower preference for the action goal determined by prior knowledge in uncertain situations. This atypical processing of prior knowledge was significantly correlated with the severity of ASD symptoms. Conclusions Our findings support the Bayesian perception theory and predictive coding theory, suggesting that children with ASD may experience difficulties in both the acquisition and application of prior knowledge in anticipation. These findings have implications for developing interventions to improve goal-directed anticipation and reduce social and communication difficulties in individuals with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102199 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509 [article] Goal-directed action anticipation and prediction error processing in children with autism spectrum disorders: An eye-movement study [Texte imprimé et/ou numérique] / Cheng-Hui TAN, Auteur ; Qi-Qi XING, Auteur ; Yuan ZHAO, Auteur ; Bo-Hai SONG, Auteur ; Chuan-Lin ZHU, Auteur ; Jun-Jie QIU, Auteur ; Mu-Ye HE, Auteur ; Dian-Zhi LIU, Auteur . - 2023 . - 102199. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 106 (August 2023) . - 102199 Mots-clés : Autism spectrum disorder  Goal-directed action anticipation  Prediction error  Eye-movement Index. décimale : PER Périodiques Résumé : Background Differences in predictive ability have been proposed as a possible explanation for the core symptoms of autism spectrum disorder (ASD). This study aimed to investigate potential differences in prior knowledge acquisition and application for goal-directed anticipation in children with ASD. Method The study included 22 children with ASD and 19 typically developing (TD) children between the ages of 5-10 years. Two eye-tracking phases were used to examine the formation of goal-directed action anticipations and the processing of action prediction errors. In the action anticipation formation phase, participants were asked to observe goal-directed actions repeatedly to examine prior knowledge acquisition about agent-goal association. In the action anticipation violation phase, the goals of actions were changed to examine the application of previously acquired knowledge. Results Children with ASD required more trials to form goal-directed anticipations than TD children. Furthermore, prior knowledge acquisition was characterized by variability and instability in children with ASD. During the action anticipation violation phase, children with ASD exhibited lower preference for the action goal determined by prior knowledge in uncertain situations. This atypical processing of prior knowledge was significantly correlated with the severity of ASD symptoms. Conclusions Our findings support the Bayesian perception theory and predictive coding theory, suggesting that children with ASD may experience difficulties in both the acquisition and application of prior knowledge in anticipation. These findings have implications for developing interventions to improve goal-directed anticipation and reduce social and communication difficulties in individuals with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102199 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509

Motivation for real-life social engagement of preschool children with autism spectrum disorder: From the caregiver perspectives / Tzu-Ting YU in Research in Autism Spectrum Disorders, 106 (August 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 106 (August 2023) . - 102205 Titre : Motivation for real-life social engagement of preschool children with autism spectrum disorder: From the caregiver perspectives Type de document : Texte imprimé et/ou numérique Auteurs : Tzu-Ting YU, Auteur ; Yu-Wei Ryan CHEN, Auteur ; Cheng-Te CHEN, Auteur ; Kuan-Lin CHEN, Auteur Année de publication : 2023 Article en page(s) : 102205 Langues : Anglais (eng) Mots-clés : Social motivation  Real-life experience  Autism spectrum disorder  Self-determination theory  Experience sampling methodology Index. décimale : PER Périodiques Résumé : Background Whether preschool children with autism spectrum disorder (ASD) have motivation for social engagement is a matter of great concern. However, the current findings derived in laboratory settings are still controversial, probably because the motivation for social engagement depends on the specific social contexts. Therefore, we compared the motivation for real-life social engagement between preschool children with ASD and typically developing (TD) peers from the caregivers' perspectives using the self-determination theory (SDT) and experience sampling methodology (ESM). The SDT helped us to examine the impact of living contexts on the motivation for social engagement, and the ESM allowed us to record objective and subjective experiences in real time across natural settings. Method Thirty preschool children with ASD and 30 matched TD peers were recruited. Caregivers carried mobile devices to record their children?s social experiences repeatedly over seven days. Multilevel modelling was used for analysis. Results Regardless of ASD, preschool children were more likely to be autonomous and intrinsically motivated while engaging in social play/leisure activities, but less likely to be autonomous, competent, and intrinsically motivated in non-play/leisure activities involving social interactions. The ASD group was also less likely to care about others or to be cared about in social play/leisure activities. Conclusions The findings highlight that the motivation for social engagement in preschool children with ASD is situation-specific and emphasize the importance of providing a supportive environment and encouraging engagement in social play/leisure activities. En ligne : https://doi.org/10.1016/j.rasd.2023.102205 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509 [article] Motivation for real-life social engagement of preschool children with autism spectrum disorder: From the caregiver perspectives [Texte imprimé et/ou numérique] / Tzu-Ting YU, Auteur ; Yu-Wei Ryan CHEN, Auteur ; Cheng-Te CHEN, Auteur ; Kuan-Lin CHEN, Auteur . - 2023 . - 102205. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 106 (August 2023) . - 102205 Mots-clés : Social motivation  Real-life experience  Autism spectrum disorder  Self-determination theory  Experience sampling methodology Index. décimale : PER Périodiques Résumé : Background Whether preschool children with autism spectrum disorder (ASD) have motivation for social engagement is a matter of great concern. However, the current findings derived in laboratory settings are still controversial, probably because the motivation for social engagement depends on the specific social contexts. Therefore, we compared the motivation for real-life social engagement between preschool children with ASD and typically developing (TD) peers from the caregivers' perspectives using the self-determination theory (SDT) and experience sampling methodology (ESM). The SDT helped us to examine the impact of living contexts on the motivation for social engagement, and the ESM allowed us to record objective and subjective experiences in real time across natural settings. Method Thirty preschool children with ASD and 30 matched TD peers were recruited. Caregivers carried mobile devices to record their children?s social experiences repeatedly over seven days. Multilevel modelling was used for analysis. Results Regardless of ASD, preschool children were more likely to be autonomous and intrinsically motivated while engaging in social play/leisure activities, but less likely to be autonomous, competent, and intrinsically motivated in non-play/leisure activities involving social interactions. The ASD group was also less likely to care about others or to be cared about in social play/leisure activities. Conclusions The findings highlight that the motivation for social engagement in preschool children with ASD is situation-specific and emphasize the importance of providing a supportive environment and encouraging engagement in social play/leisure activities. En ligne : https://doi.org/10.1016/j.rasd.2023.102205 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=509