Cognitive-behavioral therapy for anxiety in youth with an autism spectrum disorder: A follow-up study / Robert R. SELLES in Autism, 19-5 (July 2015)  

Public ISBD [article]  inAutism > 19-5 (July 2015) . - p.613-621 Titre : Cognitive-behavioral therapy for anxiety in youth with an autism spectrum disorder: A follow-up study Type de document : texte imprimé Auteurs : Robert R. SELLES, Auteur ; Elysse B. ARNOLD, Auteur ; Vicky PHARES, Auteur ; Adam B. LEWIN, Auteur ; Tanya K. MURPHY, Auteur ; Eric A. STORCH, Auteur Article en page(s) : p.613-621 Langues : Anglais (eng) Mots-clés : efficacy  maintenance  relapse  treatment Index. décimale : PER Périodiques Résumé : Cognitive-behavioral therapy for anxiety in youth with an autism spectrum disorder appears efficacious; however, maintenance of treatment gains has not yet been studied. Using a sample of 32 youth who had benefited at least minimally from a past trial of cognitive-behavioral therapy for anxiety in autism spectrum disorder, this study assessed anxiety symptoms in youth 10–26 months following treatment completion. Compared to baseline, follow-up scores were associated with large effects for treatment. Relative to post-treatment, a small effect for return in symptoms was present and significantly fewer individuals were rated as responders at follow-up. Future studies should investigate factors associated with poor treatment maintenance and modifications or additions to treatment that may help maintain treatment gains. En ligne : http://dx.doi.org/10.1177/1362361314537912 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261 [article] Cognitive-behavioral therapy for anxiety in youth with an autism spectrum disorder: A follow-up study [texte imprimé] / Robert R. SELLES, Auteur ; Elysse B. ARNOLD, Auteur ; Vicky PHARES, Auteur ; Adam B. LEWIN, Auteur ; Tanya K. MURPHY, Auteur ; Eric A. STORCH, Auteur . - p.613-621. Langues : Anglais (eng) in Autism > 19-5 (July 2015) . - p.613-621 Mots-clés : efficacy  maintenance  relapse  treatment Index. décimale : PER Périodiques Résumé : Cognitive-behavioral therapy for anxiety in youth with an autism spectrum disorder appears efficacious; however, maintenance of treatment gains has not yet been studied. Using a sample of 32 youth who had benefited at least minimally from a past trial of cognitive-behavioral therapy for anxiety in autism spectrum disorder, this study assessed anxiety symptoms in youth 10–26 months following treatment completion. Compared to baseline, follow-up scores were associated with large effects for treatment. Relative to post-treatment, a small effect for return in symptoms was present and significantly fewer individuals were rated as responders at follow-up. Future studies should investigate factors associated with poor treatment maintenance and modifications or additions to treatment that may help maintain treatment gains. En ligne : http://dx.doi.org/10.1177/1362361314537912 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261

Neurocognitive risk markers in pediatric obsessive-compulsive disorder / Juliana NEGREIROS in Journal of Child Psychology and Psychiatry, 61-5 (May 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-5 (May 2020) . - p.605-613 Titre : Neurocognitive risk markers in pediatric obsessive-compulsive disorder Type de document : texte imprimé Auteurs : Juliana NEGREIROS, Auteur ; Laura BELSCHNER, Auteur ; John R. BEST, Auteur ; Sarah LIN, Auteur ; Diana FRANCO YAMIN, Auteur ; Yayuk JOFFRES, Auteur ; Robert R. SELLES, Auteur ; Fern JASPERS-FAYER, Auteur ; Lynn D. MILLER, Auteur ; Todd S. WOODWARD, Auteur ; William G. HONER, Auteur ; S. Evelyn STEWART, Auteur Article en page(s) : p.605-613 Langues : Anglais (eng) Mots-clés : Cognitive  Obsessive-compulsive disorder  biomarker  genetics  pediatrics Index. décimale : PER Périodiques Résumé : BACKGROUND: Obsessive-compulsive disorder (OCD) has complex genetic underpinnings, particularly in its early-onset form, which places siblings at a 10-fold increased risk of developing the disorder. Examination for neurocognitive markers preceding pediatric OCD onset has not been conducted, although markers have been identified in adult OCD. This study compared neurocognition across groups of OCD-affected youth (n = 87), unaffected siblings of those with early-onset OCD (n = 67), and healthy controls (HC; n = 79). METHODS: A total of 233 participants aged 6-18 years old completed standardized neurocognitive tests of cognitive flexibility, decision making, planning, response inhibition, spatial working memory, attention, recognition nonverbal memory, and intelligence. They were administered the Anxiety Disorders Interview Schedule-Parent version (ADIS-P) and completed self-report anxiety and OCD questionnaires. Linear mixed-effects models tested for differences between groups, adjusting for age, gender, IQ, state anxiety, and ethnicity, and accounting for random effects of family membership. RESULTS: OCD-affected youth and unaffected siblings performed significantly worse on planning in comparison to HCs (Cohen's d = 0.74; 95% CI = [0.11, 1.36]; Cohen's d = 0.75; 95% CI = [0.12, 1.38], respectively; omnibus group effect p = .007). No other significant between-group differences were identified. CONCLUSIONS: Neurocognitive performance differences between groups identified planning as a preexisting trait marker of pediatric OCD, while no other domain presented as a marker of pediatric OCD. This differs from adult OCD, which is associated with broader cognitive impairments. Investigating longitudinal trajectories and predictive significance of neurocognition in those affected by, and at risk for, early-onset OCD is warranted. Ideally, this will enhance individualized risk stratification and inform future prevention and early intervention strategies. En ligne : http://dx.doi.org/10.1111/jcpp.13153 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422 [article] Neurocognitive risk markers in pediatric obsessive-compulsive disorder [texte imprimé] / Juliana NEGREIROS, Auteur ; Laura BELSCHNER, Auteur ; John R. BEST, Auteur ; Sarah LIN, Auteur ; Diana FRANCO YAMIN, Auteur ; Yayuk JOFFRES, Auteur ; Robert R. SELLES, Auteur ; Fern JASPERS-FAYER, Auteur ; Lynn D. MILLER, Auteur ; Todd S. WOODWARD, Auteur ; William G. HONER, Auteur ; S. Evelyn STEWART, Auteur . - p.605-613. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-5 (May 2020) . - p.605-613 Mots-clés : Cognitive  Obsessive-compulsive disorder  biomarker  genetics  pediatrics Index. décimale : PER Périodiques Résumé : BACKGROUND: Obsessive-compulsive disorder (OCD) has complex genetic underpinnings, particularly in its early-onset form, which places siblings at a 10-fold increased risk of developing the disorder. Examination for neurocognitive markers preceding pediatric OCD onset has not been conducted, although markers have been identified in adult OCD. This study compared neurocognition across groups of OCD-affected youth (n = 87), unaffected siblings of those with early-onset OCD (n = 67), and healthy controls (HC; n = 79). METHODS: A total of 233 participants aged 6-18 years old completed standardized neurocognitive tests of cognitive flexibility, decision making, planning, response inhibition, spatial working memory, attention, recognition nonverbal memory, and intelligence. They were administered the Anxiety Disorders Interview Schedule-Parent version (ADIS-P) and completed self-report anxiety and OCD questionnaires. Linear mixed-effects models tested for differences between groups, adjusting for age, gender, IQ, state anxiety, and ethnicity, and accounting for random effects of family membership. RESULTS: OCD-affected youth and unaffected siblings performed significantly worse on planning in comparison to HCs (Cohen's d = 0.74; 95% CI = [0.11, 1.36]; Cohen's d = 0.75; 95% CI = [0.12, 1.38], respectively; omnibus group effect p = .007). No other significant between-group differences were identified. CONCLUSIONS: Neurocognitive performance differences between groups identified planning as a preexisting trait marker of pediatric OCD, while no other domain presented as a marker of pediatric OCD. This differs from adult OCD, which is associated with broader cognitive impairments. Investigating longitudinal trajectories and predictive significance of neurocognition in those affected by, and at risk for, early-onset OCD is warranted. Ideally, this will enhance individualized risk stratification and inform future prevention and early intervention strategies. En ligne : http://dx.doi.org/10.1111/jcpp.13153 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422

The relationship between peer victimization and the psychological characteristics of youth with autism spectrum disorder / Danielle UNG in Research in Autism Spectrum Disorders, 32 (December 2016)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 32 (December 2016) . - p.70-79 Titre : The relationship between peer victimization and the psychological characteristics of youth with autism spectrum disorder Type de document : texte imprimé Auteurs : Danielle UNG, Auteur ; Nicole M. MCBRIDE, Auteur ; Amanda COLLIER, Auteur ; Robert R. SELLES, Auteur ; Brent J. SMALL, Auteur ; Vicky PHARES, Auteur ; Eric STORCH, Auteur Article en page(s) : p.70-79 Langues : Anglais (eng) Mots-clés : Victimization  Bullying  Autism  Social support  Anxiety  Depression  Loneliness Index. décimale : PER Périodiques Résumé : AbstractBackground Youth with autism spectrum disorder (ASD) are frequently victimized. Acts of peer victimization of youth with ASD can lead to the development of detrimental and maladaptive behavioral problems. The purpose of this study is to examine the relationship between peer victimization and the psychological characteristics of youth with ASD. Method Study participants were 81 school-aged youth with ASD between the ages of 9 and 17 years and had an intelligence quotient (IQ) ≥ 70 and their parents. Participants completed questionnaires examining the frequency of peer victimization and clinical characteristics of the youth. Results Victimization had a significant positive relationship with child’s loneliness and anxiety and depressive symptoms, and a significant negative relationship with social skills. The relationship between victimization and these symptoms did not significantly vary as a function of social support. The relationship between victimization and social avoidance was not mediated by a fear of negative evaluation. Conclusions These results may assist in identifying risk factors for peer victimization in youth with ASD and may help to shape treatment protocols by targeting the associated factors of peer victimization (e.g., anxiety and depressive symptoms, social skill deficits). En ligne : http://dx.doi.org/10.1016/j.rasd.2016.09.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=296 [article] The relationship between peer victimization and the psychological characteristics of youth with autism spectrum disorder [texte imprimé] / Danielle UNG, Auteur ; Nicole M. MCBRIDE, Auteur ; Amanda COLLIER, Auteur ; Robert R. SELLES, Auteur ; Brent J. SMALL, Auteur ; Vicky PHARES, Auteur ; Eric STORCH, Auteur . - p.70-79. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 32 (December 2016) . - p.70-79 Mots-clés : Victimization  Bullying  Autism  Social support  Anxiety  Depression  Loneliness Index. décimale : PER Périodiques Résumé : AbstractBackground Youth with autism spectrum disorder (ASD) are frequently victimized. Acts of peer victimization of youth with ASD can lead to the development of detrimental and maladaptive behavioral problems. The purpose of this study is to examine the relationship between peer victimization and the psychological characteristics of youth with ASD. Method Study participants were 81 school-aged youth with ASD between the ages of 9 and 17 years and had an intelligence quotient (IQ) ≥ 70 and their parents. Participants completed questionnaires examining the frequency of peer victimization and clinical characteristics of the youth. Results Victimization had a significant positive relationship with child’s loneliness and anxiety and depressive symptoms, and a significant negative relationship with social skills. The relationship between victimization and these symptoms did not significantly vary as a function of social support. The relationship between victimization and social avoidance was not mediated by a fear of negative evaluation. Conclusions These results may assist in identifying risk factors for peer victimization in youth with ASD and may help to shape treatment protocols by targeting the associated factors of peer victimization (e.g., anxiety and depressive symptoms, social skill deficits). En ligne : http://dx.doi.org/10.1016/j.rasd.2016.09.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=296

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