Disentangling the Overlap between Tourette's Disorder and ADHD / Thomas SPENCER in Journal of Child Psychology and Psychiatry, 39-7 (October 1998)

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 39-7 (October 1998) . - p.1037-1044 Titre : Disentangling the Overlap between Tourette's Disorder and ADHD Type de document : texte imprimé Auteurs : Thomas SPENCER, Auteur ; Joseph BIEDERMAN, Auteur ; Margaret HARDING, Auteur ; Deborah O'DONNELL, Auteur ; Timothy E. WILENS, Auteur ; Stephen V. FARAONE, Auteur ; Barbara COFFEY, Auteur ; Daniel A. GELLER, Auteur Année de publication : 1998 Article en page(s) : p.1037-1044 Langues : Anglais (eng) Mots-clés : Tourette's syndrome  attention deficit disorder  adolescence  school children  comorbidity Index. décimale : PER Périodiques Résumé : Objective: To identify similarities and differences in neuropsychiatric correlates in children with Tourette's syndrome (TS) and those with ADHD. Method: The sample consisted of children with Tourette's syndrome with ADHD(N= 79), children with Tourette's syndrome without ADHD (N= 18), children with ADHD (N= 563), psychiatrically referred children (N= 212), and healthy controls (N= 140). Results: Disorders specifically associated with Tourette's syndrome were obsessive compulsive disorder (OCD) and simple phobias. Rates of other disorders, including other disruptive behavioral, mood, and anxiety disorders, neuropsychologic correlates, and social and school functioning were indistinguishable in children with Tourette's and ADHD. However, children with Tourette's syndrome plus ADHD had more additional comorbid disorders overall and lower psychosocial function than children with ADHD. Conclusions: These findings confirm previously noted associations between Tourette's syndrome and OCD but suggest that disruptive behavioral, mood, and anxiety disorders as well as cognitive dysfunctions may be accounted for by comorbidity with ADHD. However, Tourette's syndrome plus ADHD appears to be a more severe condition than ADHD alone. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=123 [article] Disentangling the Overlap between Tourette's Disorder and ADHD [texte imprimé] / Thomas SPENCER, Auteur ; Joseph BIEDERMAN, Auteur ; Margaret HARDING, Auteur ; Deborah O'DONNELL, Auteur ; Timothy E. WILENS, Auteur ; Stephen V. FARAONE, Auteur ; Barbara COFFEY, Auteur ; Daniel A. GELLER, Auteur . - 1998 . - p.1037-1044. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 39-7 (October 1998) . - p.1037-1044 Mots-clés : Tourette's syndrome  attention deficit disorder  adolescence  school children  comorbidity Index. décimale : PER Périodiques Résumé : Objective: To identify similarities and differences in neuropsychiatric correlates in children with Tourette's syndrome (TS) and those with ADHD. Method: The sample consisted of children with Tourette's syndrome with ADHD(N= 79), children with Tourette's syndrome without ADHD (N= 18), children with ADHD (N= 563), psychiatrically referred children (N= 212), and healthy controls (N= 140). Results: Disorders specifically associated with Tourette's syndrome were obsessive compulsive disorder (OCD) and simple phobias. Rates of other disorders, including other disruptive behavioral, mood, and anxiety disorders, neuropsychologic correlates, and social and school functioning were indistinguishable in children with Tourette's and ADHD. However, children with Tourette's syndrome plus ADHD had more additional comorbid disorders overall and lower psychosocial function than children with ADHD. Conclusions: These findings confirm previously noted associations between Tourette's syndrome and OCD but suggest that disruptive behavioral, mood, and anxiety disorders as well as cognitive dysfunctions may be accounted for by comorbidity with ADHD. However, Tourette's syndrome plus ADHD appears to be a more severe condition than ADHD alone. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=123

Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis / Matti CERVIN in Journal of Child Psychology and Psychiatry, 65-5 (May 2024)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.594-609 Titre : Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis Type de document : texte imprimé Auteurs : Matti CERVIN, Auteur ; Joseph F. MCGUIRE, Auteur ; Johann M. D'SOUZA, Auteur ; Alessandro S. DE NADAI, Auteur ; Kristina ASPVALL, Auteur ; Wayne K. GOODMAN, Auteur ; Per ANDRÉN, Auteur ; Sophie C. SCHNEIDER, Auteur ; Daniel A. GELLER, Auteur ; David MATAIX-COLS, Auteur ; Eric A. STORCH, Auteur Article en page(s) : p.594-609 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Cognitive-behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs) are recommended treatments for pediatric obsessive-compulsive disorder (OCD), but their relative efficacy and acceptability have not been comprehensively examined. Further, it remains unclear whether the efficacy of in-person CBT is conserved when delivered in other formats, such as over telephone/webcam or as Internet-delivered CBT (ICBT). Methods PubMed, PsycINFO, trial registries, and previous systematic reviews were searched for randomized controlled trials (RCTs) comparing CBT (in-person, webcam/telephone-delivered, or ICBT) or SRIs with control conditions or each other. Network meta-analyses were conducted to examine efficacy (post-treatment Children's Yale-Brown Obsessive Compulsive Scale) and acceptability (treatment discontinuation). Confidence in effect estimates was evaluated with CINeMA (Confidence in Network Meta-Analysis). Results Thirty eligible RCTs and 35 contrasts comprising 2,057 youth with OCD were identified. In-person CBT was significantly more efficacious than ICBT, waitlist, relaxation training, and pill placebo (MD range: 3.95-11.10; CINeMA estimate of confidence: moderate) but did not differ significantly from CBT delivered via webcam/telephone (MD: 0.85 [ 2.51, 4.21]; moderate), SRIs (MD: 3.07 [ 0.07, 6.20]; low), or the combination of in-person CBT and SRIs (MD: 1.20 [ 5.29, 2.91]; low). SRIs were significantly more efficacious than pill placebo (MD: 4.59 [2.70, 6.48]; low) and waitlist (MD: 8.03 [4.24, 11.82]; moderate). No significant differences for acceptability emerged, but confidence in estimates was low. Conclusions In-person CBT and SRIs produce clear benefits compared to waitlist and pill placebo and should be integral parts of the clinical management of pediatric OCD, with in-person CBT overall having a stronger evidence base. The combination of in-person CBT and SRIs may be most efficacious, but few studies hinder firm conclusions. The efficacy of CBT appears conserved when delivered via webcam/telephone, while more trials evaluating ICBT are needed. En ligne : https://doi.org/10.1111/jcpp.13934 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526 [article] Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis [texte imprimé] / Matti CERVIN, Auteur ; Joseph F. MCGUIRE, Auteur ; Johann M. D'SOUZA, Auteur ; Alessandro S. DE NADAI, Auteur ; Kristina ASPVALL, Auteur ; Wayne K. GOODMAN, Auteur ; Per ANDRÉN, Auteur ; Sophie C. SCHNEIDER, Auteur ; Daniel A. GELLER, Auteur ; David MATAIX-COLS, Auteur ; Eric A. STORCH, Auteur . - p.594-609. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.594-609 Index. décimale : PER Périodiques Résumé : Background Cognitive-behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs) are recommended treatments for pediatric obsessive-compulsive disorder (OCD), but their relative efficacy and acceptability have not been comprehensively examined. Further, it remains unclear whether the efficacy of in-person CBT is conserved when delivered in other formats, such as over telephone/webcam or as Internet-delivered CBT (ICBT). Methods PubMed, PsycINFO, trial registries, and previous systematic reviews were searched for randomized controlled trials (RCTs) comparing CBT (in-person, webcam/telephone-delivered, or ICBT) or SRIs with control conditions or each other. Network meta-analyses were conducted to examine efficacy (post-treatment Children's Yale-Brown Obsessive Compulsive Scale) and acceptability (treatment discontinuation). Confidence in effect estimates was evaluated with CINeMA (Confidence in Network Meta-Analysis). Results Thirty eligible RCTs and 35 contrasts comprising 2,057 youth with OCD were identified. In-person CBT was significantly more efficacious than ICBT, waitlist, relaxation training, and pill placebo (MD range: 3.95-11.10; CINeMA estimate of confidence: moderate) but did not differ significantly from CBT delivered via webcam/telephone (MD: 0.85 [ 2.51, 4.21]; moderate), SRIs (MD: 3.07 [ 0.07, 6.20]; low), or the combination of in-person CBT and SRIs (MD: 1.20 [ 5.29, 2.91]; low). SRIs were significantly more efficacious than pill placebo (MD: 4.59 [2.70, 6.48]; low) and waitlist (MD: 8.03 [4.24, 11.82]; moderate). No significant differences for acceptability emerged, but confidence in estimates was low. Conclusions In-person CBT and SRIs produce clear benefits compared to waitlist and pill placebo and should be integral parts of the clinical management of pediatric OCD, with in-person CBT overall having a stronger evidence base. The combination of in-person CBT and SRIs may be most efficacious, but few studies hinder firm conclusions. The efficacy of CBT appears conserved when delivered via webcam/telephone, while more trials evaluating ICBT are needed. En ligne : https://doi.org/10.1111/jcpp.13934 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526

Research Review: Neuropsychological test performance in pediatric obsessive–compulsive disorder – a meta-analysis / Amitai ABRAMOVITCH in Journal of Child Psychology and Psychiatry, 56-8 (August 2015)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 56-8 (August 2015) . - p.837-847 Titre : Research Review: Neuropsychological test performance in pediatric obsessive–compulsive disorder – a meta-analysis Type de document : texte imprimé Auteurs : Amitai ABRAMOVITCH, Auteur ; Jonathan S. ABRAMOWITZ, Auteur ; Andrew MITTELMAN, Auteur ; Abigail STARK, Auteur ; Kesley RAMSEY, Auteur ; Daniel A. GELLER, Auteur Article en page(s) : p.837-847 Langues : Anglais (eng) Mots-clés : Obsessive–compulsive disorder  pediatric  neuropsychology  meta-analysis  executive function  developmental  cognitive functions Index. décimale : PER Périodiques Résumé : Background Research into the neuropsychology of pediatric obsessive–compulsive disorder (OCD) reveals inconsistent results, limiting the ability to draw conclusions about possible neurocognitive deficits in youth with OCD. The aim of this study was to conduct a meta-analysis of the available literature. Methods We identified 36 studies, of which 11 studies met inclusion criteria. Results were categorized into nine functional subdomains: planning, response inhibition/interference control, set shifting/cognitive flexibility, verbal memory, nonverbal memory, processing speed, working memory, visuospatial functions, and attention. For each domain, weighted pooled Hedges' g effect size was calculated using random model analyses. Results Small effect sizes were found across all subdomains, none of which were found to be statistically significant. Discussion Results indicate that youth with OCD do not exhibit noteworthy neuropsychological deficits. This is in line with recent suggestions that OCD may not be characterized by clinically meaningful neuropsychological impairments. However, the small number of available controlled studies highlights the urgent need for more neuropsychological research in this population, as well as for further exploration of the neurodevelopmental hypothesis in pediatric OCD. Finally, the relatively low persistence rates of OCD into adulthood should be taken under consideration, especially in the context of the putative neuropsychological performance differences between adult and pediatric OCD populations. En ligne : http://dx.doi.org/10.1111/jcpp.12414 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263 [article] Research Review: Neuropsychological test performance in pediatric obsessive–compulsive disorder – a meta-analysis [texte imprimé] / Amitai ABRAMOVITCH, Auteur ; Jonathan S. ABRAMOWITZ, Auteur ; Andrew MITTELMAN, Auteur ; Abigail STARK, Auteur ; Kesley RAMSEY, Auteur ; Daniel A. GELLER, Auteur . - p.837-847. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 56-8 (August 2015) . - p.837-847 Mots-clés : Obsessive–compulsive disorder  pediatric  neuropsychology  meta-analysis  executive function  developmental  cognitive functions Index. décimale : PER Périodiques Résumé : Background Research into the neuropsychology of pediatric obsessive–compulsive disorder (OCD) reveals inconsistent results, limiting the ability to draw conclusions about possible neurocognitive deficits in youth with OCD. The aim of this study was to conduct a meta-analysis of the available literature. Methods We identified 36 studies, of which 11 studies met inclusion criteria. Results were categorized into nine functional subdomains: planning, response inhibition/interference control, set shifting/cognitive flexibility, verbal memory, nonverbal memory, processing speed, working memory, visuospatial functions, and attention. For each domain, weighted pooled Hedges' g effect size was calculated using random model analyses. Results Small effect sizes were found across all subdomains, none of which were found to be statistically significant. Discussion Results indicate that youth with OCD do not exhibit noteworthy neuropsychological deficits. This is in line with recent suggestions that OCD may not be characterized by clinically meaningful neuropsychological impairments. However, the small number of available controlled studies highlights the urgent need for more neuropsychological research in this population, as well as for further exploration of the neurodevelopmental hypothesis in pediatric OCD. Finally, the relatively low persistence rates of OCD into adulthood should be taken under consideration, especially in the context of the putative neuropsychological performance differences between adult and pediatric OCD populations. En ligne : http://dx.doi.org/10.1111/jcpp.12414 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263

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