Autism Spectrum Disorder Phenotypes Based on Sleep Dimensions and Core Autism Symptoms / Kristina P. LENKER in Journal of Autism and Developmental Disorders, 55-12 (December 2025)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 55-12 (December 2025) . - p.4412-4424 Titre : Autism Spectrum Disorder Phenotypes Based on Sleep Dimensions and Core Autism Symptoms Type de document : texte imprimé Auteurs : Kristina P. LENKER, Auteur ; Yanling LI, Auteur ; Julio FERNANDEZ-MENDOZA, Auteur ; Susan D. MAYES, Auteur ; Susan L. CALHOUN, Auteur Article en page(s) : p.4412-4424 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Previous studies have used cluster analysis to address the diagnostic heterogeneity of autism spectrum disorder, but have been limited by identifying subgroups solely on the basis of core autism symptoms. The present study aimed to identify sleep phenotypes and their clustering with core autism symptoms in youth diagnosed with autism. 1397 patients (1-17y, M = 6.1 ± 3.3y; M IQ = 88.5 ± 27.2; 81.2% male, 89.0% white) with autism. Principal component analysis (PCA) was performed on 10 sleep items from the Pediatric Behavior Scale. Latent class analyses (LCA) determined phenotypes characterized by core autism symptoms and sleep clusters, accounting for age, sex, Intelligence Quotient (IQ), and medication use.PCA identified three distinct sleep clusters (disturbed sleep, insufficient sleep and hypersomnolence) explaining 48.4% of the variance. LCA revealed four phenotypes based on core ASD symptoms and sleep clusters. Compared to Class 1 (54.8%) as the reference group, Class 2 (26.3%) had a similar degree of sleep problems, higher IQ and milder autism symptoms, less problems with selective attention/fearlessness; Class 3 (14.5%) was characterized by insufficient and disturbed sleep, perseveration and somatosensory disturbance, and higher medication use, while Class 4 (4.4%) was by hypersomnolence, problems with social interactions, and higher medication use.We found four distinct clustering of core autism symptoms and sleep problems differing in their sleep profiles as well as in relation to clinical characteristics, demographics, internalizing/externalizing symptoms, and functional outcomes. Our findings underscore the heterogeneity of autism based on sleep-wake problems, advocating for personalized therapeutic interventions targeting nighttime sleep and daytime alertness. En ligne : https://doi.org/10.1007/s10803-025-06822-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572 [article] Autism Spectrum Disorder Phenotypes Based on Sleep Dimensions and Core Autism Symptoms [texte imprimé] / Kristina P. LENKER, Auteur ; Yanling LI, Auteur ; Julio FERNANDEZ-MENDOZA, Auteur ; Susan D. MAYES, Auteur ; Susan L. CALHOUN, Auteur . - p.4412-4424. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 55-12 (December 2025) . - p.4412-4424 Index. décimale : PER Périodiques Résumé : Previous studies have used cluster analysis to address the diagnostic heterogeneity of autism spectrum disorder, but have been limited by identifying subgroups solely on the basis of core autism symptoms. The present study aimed to identify sleep phenotypes and their clustering with core autism symptoms in youth diagnosed with autism. 1397 patients (1-17y, M = 6.1 ± 3.3y; M IQ = 88.5 ± 27.2; 81.2% male, 89.0% white) with autism. Principal component analysis (PCA) was performed on 10 sleep items from the Pediatric Behavior Scale. Latent class analyses (LCA) determined phenotypes characterized by core autism symptoms and sleep clusters, accounting for age, sex, Intelligence Quotient (IQ), and medication use.PCA identified three distinct sleep clusters (disturbed sleep, insufficient sleep and hypersomnolence) explaining 48.4% of the variance. LCA revealed four phenotypes based on core ASD symptoms and sleep clusters. Compared to Class 1 (54.8%) as the reference group, Class 2 (26.3%) had a similar degree of sleep problems, higher IQ and milder autism symptoms, less problems with selective attention/fearlessness; Class 3 (14.5%) was characterized by insufficient and disturbed sleep, perseveration and somatosensory disturbance, and higher medication use, while Class 4 (4.4%) was by hypersomnolence, problems with social interactions, and higher medication use.We found four distinct clustering of core autism symptoms and sleep problems differing in their sleep profiles as well as in relation to clinical characteristics, demographics, internalizing/externalizing symptoms, and functional outcomes. Our findings underscore the heterogeneity of autism based on sleep-wake problems, advocating for personalized therapeutic interventions targeting nighttime sleep and daytime alertness. En ligne : https://doi.org/10.1007/s10803-025-06822-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572

Brief Report: Checklist for Autism Spectrum Disorder: Most Discriminating Items for Diagnosing Autism / Susan D. MAYES in Journal of Autism and Developmental Disorders, 48-3 (March 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-3 (March 2018) . - p.935-939 Titre : Brief Report: Checklist for Autism Spectrum Disorder: Most Discriminating Items for Diagnosing Autism Type de document : texte imprimé Auteurs : Susan D. MAYES, Auteur Année de publication : 2018 Article en page(s) : p.935-939 Langues : Anglais (eng) Mots-clés : Autism diagnosis  Checklist for Autism Spectrum Disorder  Short form validity Index. décimale : PER Périodiques Résumé : The smallest subset of items from the 30-item Checklist for Autism Spectrum Disorder (CASD) that differentiated 607 referred children (3-17 years) with and without autism with 100% accuracy was identified. This 6-item subset (CASD-Short Form) was cross-validated on an independent sample of 397 referred children (1-18 years) with and without autism and on data from 1417 children in the CASD standardization sample and 1052 children in the CASD normative sample, resulting in 98.5, 97.6, and 99.8% diagnostic accuracy, respectively. Diagnostic agreement was high between the CASD-Short Form and the Autism Diagnostic Interview-Revised (96%), and the Child Autism Rating Scale (98%). Diagnostic accuracy for the CASD-SF was similar to accuracy for the 30-item CASD full form. En ligne : https://doi.org/10.1007/s10803-017-3401-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=339 [article] Brief Report: Checklist for Autism Spectrum Disorder: Most Discriminating Items for Diagnosing Autism [texte imprimé] / Susan D. MAYES, Auteur . - 2018 . - p.935-939. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-3 (March 2018) . - p.935-939 Mots-clés : Autism diagnosis  Checklist for Autism Spectrum Disorder  Short form validity Index. décimale : PER Périodiques Résumé : The smallest subset of items from the 30-item Checklist for Autism Spectrum Disorder (CASD) that differentiated 607 referred children (3-17 years) with and without autism with 100% accuracy was identified. This 6-item subset (CASD-Short Form) was cross-validated on an independent sample of 397 referred children (1-18 years) with and without autism and on data from 1417 children in the CASD standardization sample and 1052 children in the CASD normative sample, resulting in 98.5, 97.6, and 99.8% diagnostic accuracy, respectively. Diagnostic agreement was high between the CASD-Short Form and the Autism Diagnostic Interview-Revised (96%), and the Child Autism Rating Scale (98%). Diagnostic accuracy for the CASD-SF was similar to accuracy for the 30-item CASD full form. En ligne : https://doi.org/10.1007/s10803-017-3401-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=339

Brief Report: How Accurate is Teacher Report of Autism Symptoms Compared to Parent Report? / Susan D. MAYES in Journal of Autism and Developmental Disorders, 48-5 (May 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1833-1840 Titre : Brief Report: How Accurate is Teacher Report of Autism Symptoms Compared to Parent Report? Type de document : texte imprimé Auteurs : Susan D. MAYES, Auteur ; Robin LOCKRIDGE, Auteur Article en page(s) : p.1833-1840 Langues : Anglais (eng) Mots-clés : Autism symptoms  Checklist for Autism Spectrum Disorder  Mother, teacher, and psychologist agreement Index. décimale : PER Périodiques Résumé : The Checklist for Autism Spectrum Disorder (CASD) completed by a psychologist (following standardized procedures integrating parent interview data, teacher report, and clinical observations) was compared with the CASD completed independently by mothers and teachers in 168 children with ASD and 40 with ADHD (1-12 years). The 30 CASD autism symptoms are scored as present or absent. Using mother scores 36% of children with ASD scored below the autism diagnostic cutoff, and 75% scored below the cutoff based on teacher scores. Many symptoms deemed present by the psychologist were not reported on the mother and teacher CASD. Mother-teacher correlations indicated little correspondence. Mother and teacher CASD scores should never be used alone. Diagnostic instruments must be administered following standardized procedures. En ligne : http://dx.doi.org/10.1007/s10803-017-3325-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355 [article] Brief Report: How Accurate is Teacher Report of Autism Symptoms Compared to Parent Report? [texte imprimé] / Susan D. MAYES, Auteur ; Robin LOCKRIDGE, Auteur . - p.1833-1840. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1833-1840 Mots-clés : Autism symptoms  Checklist for Autism Spectrum Disorder  Mother, teacher, and psychologist agreement Index. décimale : PER Périodiques Résumé : The Checklist for Autism Spectrum Disorder (CASD) completed by a psychologist (following standardized procedures integrating parent interview data, teacher report, and clinical observations) was compared with the CASD completed independently by mothers and teachers in 168 children with ASD and 40 with ADHD (1-12 years). The 30 CASD autism symptoms are scored as present or absent. Using mother scores 36% of children with ASD scored below the autism diagnostic cutoff, and 75% scored below the cutoff based on teacher scores. Many symptoms deemed present by the psychologist were not reported on the mother and teacher CASD. Mother-teacher correlations indicated little correspondence. Mother and teacher CASD scores should never be used alone. Diagnostic instruments must be administered following standardized procedures. En ligne : http://dx.doi.org/10.1007/s10803-017-3325-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355

Correction: Prevalence and Correlates of Poor Safety Awareness and Accidental Injury in ASD, ADHD, ASD?+?ADHD, and Neurotypical Youth Samples / Susan D. MAYES in Journal of Autism and Developmental Disorders, 54-8 (August 2024)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 54-8 (August 2024) . - p.3193-3193 Titre : Correction: Prevalence and Correlates of Poor Safety Awareness and Accidental Injury in ASD, ADHD, ASD?+?ADHD, and Neurotypical Youth Samples Type de document : texte imprimé Auteurs : Susan D. MAYES, Auteur Article en page(s) : p.3193-3193 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1007/s10803-024-06442-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Correction: Prevalence and Correlates of Poor Safety Awareness and Accidental Injury in ASD, ADHD, ASD?+?ADHD, and Neurotypical Youth Samples [texte imprimé] / Susan D. MAYES, Auteur . - p.3193-3193. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 54-8 (August 2024) . - p.3193-3193 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1007/s10803-024-06442-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Disruptive mood dysregulation disorder (DMDD) symptoms in children with autism, ADHD, and neurotypical development and impact of co-occurring ODD, depression, and anxiety / Susan D. MAYES in Research in Autism Spectrum Disorders, 18 (October 2015)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 18 (October 2015) . - p.64-72 Titre : Disruptive mood dysregulation disorder (DMDD) symptoms in children with autism, ADHD, and neurotypical development and impact of co-occurring ODD, depression, and anxiety Type de document : texte imprimé Auteurs : Susan D. MAYES, Auteur ; James WAXMONSKY, Auteur ; Susan L. CALHOUN, Auteur ; C. KOKOTOVICH, Auteur ; C. MATHIOWETZ, Auteur ; Raman BAWEJA, Auteur Article en page(s) : p.64-72 Langues : Anglais (eng) Mots-clés : Disruptive mood dysregulation disorder  Autism  ADHD  ODD  Neurotypical Index. décimale : PER Périodiques Résumé : Abstract Disruptive mood dysregulation disorder (DMDD) is a controversial diagnosis introduced in the DSM-5 that is particularly relevant to autism and other disorders in which DMDD symptoms (irritable-angry mood and temper outbursts) are common. Mothers rated DMDD symptoms in 1593 children with autism, ADHD, and neurotypical development (6–16 years, IQ ≥ 80). Percentages with DMDD symptoms (often or very often) were autism 45%, ADHD-Combined type 39%, ADHD-Inattentive type 12%, and neurotypical 3%. Almost all (91%) with DMDD symptoms met DSM-5 criteria for ODD, and 79% with ODD had DMDD symptoms. Only 5% without ODD had DMDD symptoms, and most of these had autism. Children with autism had significantly higher DMDD scores than all other groups, even when the oppositional behavior score (excluding the two DMDD symptoms) was controlled. The findings suggest that DMDD and ODD are not meaningfully differentiated based on their symptoms and that DMDD symptoms are particularly common in autism, more so than expected by comorbid ODD alone. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.07.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268 [article] Disruptive mood dysregulation disorder (DMDD) symptoms in children with autism, ADHD, and neurotypical development and impact of co-occurring ODD, depression, and anxiety [texte imprimé] / Susan D. MAYES, Auteur ; James WAXMONSKY, Auteur ; Susan L. CALHOUN, Auteur ; C. KOKOTOVICH, Auteur ; C. MATHIOWETZ, Auteur ; Raman BAWEJA, Auteur . - p.64-72. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 18 (October 2015) . - p.64-72 Mots-clés : Disruptive mood dysregulation disorder  Autism  ADHD  ODD  Neurotypical Index. décimale : PER Périodiques Résumé : Abstract Disruptive mood dysregulation disorder (DMDD) is a controversial diagnosis introduced in the DSM-5 that is particularly relevant to autism and other disorders in which DMDD symptoms (irritable-angry mood and temper outbursts) are common. Mothers rated DMDD symptoms in 1593 children with autism, ADHD, and neurotypical development (6–16 years, IQ ≥ 80). Percentages with DMDD symptoms (often or very often) were autism 45%, ADHD-Combined type 39%, ADHD-Inattentive type 12%, and neurotypical 3%. Almost all (91%) with DMDD symptoms met DSM-5 criteria for ODD, and 79% with ODD had DMDD symptoms. Only 5% without ODD had DMDD symptoms, and most of these had autism. Children with autism had significantly higher DMDD scores than all other groups, even when the oppositional behavior score (excluding the two DMDD symptoms) was controlled. The findings suggest that DMDD and ODD are not meaningfully differentiated based on their symptoms and that DMDD symptoms are particularly common in autism, more so than expected by comorbid ODD alone. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.07.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268

Methods and Procedures for Measuring Comorbid Disorders: Psychological / Amanda M. PEARL  

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Oppositional Defiant Disorder in Autism and ADHD / Susan D. MAYES in Journal of Autism and Developmental Disorders, 55-11 (November 2025)  

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Prevalence and Correlates of Poor Safety Awareness and Accidental Injury in ASD, ADHD, ASD?+?ADHD, and Neurotypical Youth Samples / Sara K. PARDEJ in Journal of Autism and Developmental Disorders, 55-9 (September 2025)  

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Relationship between cognitive disengagement syndrome (CDS) (formerly sluggish cognitive tempo) and social functioning in child autism, ADHD, and elementary school samples / Susan D. MAYES in Research in Autism Spectrum Disorders, 108 (October 2023)  

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Relationship Between Sluggish Cognitive Tempo and Age and IQ in Preschool and School-Age Children and Adolescents with Autism and with ADHD / Susan D. MAYES in Journal of Autism and Developmental Disorders, 52-8 (August 2022)  

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Relative Frequency of Psychiatric, Neurodevelopmental, and Somatic Symptoms as Reported by Mothers of Children with Autism Compared with ADHD and Typical Samples / Susan D. MAYES in Journal of Autism and Developmental Disorders, 51-7 (July 2021)  

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Sleep Disturbances Increase the Impact of Working Memory Deficits on Learning Problems in Adolescents with High-Functioning Autism Spectrum Disorder / Susan L. CALHOUN in Journal of Autism and Developmental Disorders, 50-5 (May 2020)  

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Sluggish cognitive tempo in autism, ADHD, and neurotypical child samples / Susan D. MAYES in Research in Autism Spectrum Disorders, 79 (November 2020)  

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