Health conditions in autism: Defining the trajectory from adolescence to early adulthood / Beth A. MALOW in Autism Research, 16-7 (July 2023)  

Public ISBD [article]  inAutism Research > 16-7 (July 2023) . - p.1437-1449 Titre : Health conditions in autism: Defining the trajectory from adolescence to early adulthood Type de document : texte imprimé Auteurs : Beth A. MALOW, Auteur ; Yinge QIAN, Auteur ; Jennifer L. AMES, Auteur ; Stacey E. ALEXEEFF, Auteur ; Lisa A. CROEN, Auteur Article en page(s) : p.1437-1449 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Autistic adults, as compared to non-autistic adults, have increased rates of nearly all medical and psychiatric conditions. Many of these conditions begin in childhood, although few longitudinal studies have been conducted to examine prevalence rates of these conditions from adolescence into early adulthood. In this study, we analyze the longitudinal trajectory of health conditions in autistic youth, compared to age and sex-matched non-autistic youth, transitioning from adolescence into early adulthood in a large integrated health care delivery system. The percent and modeled prevalence of common medical and psychiatric conditions increased from age 14 to 22 years, with autistic youth having a higher prevalence of most conditions than non-autistic youth. The most prevalent conditions in autistic youth at all ages were obesity, neurological disorders, anxiety, and ADHD. The prevalence of obesity and dyslipidemia rose at a faster rate in autistic youth compared to non-autistic youth. By age 22, autistic females showed a higher prevalence of all medical and psychiatric conditions compared to autistic males. Our findings emphasize the importance of screening for medical and psychiatric conditions in autistic youth, coupled with health education targeted at this population, to mitigate the development of adverse health outcomes in autistic adults. En ligne : https://doi.org/10.1002/aur.2960 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Health conditions in autism: Defining the trajectory from adolescence to early adulthood [texte imprimé] / Beth A. MALOW, Auteur ; Yinge QIAN, Auteur ; Jennifer L. AMES, Auteur ; Stacey E. ALEXEEFF, Auteur ; Lisa A. CROEN, Auteur . - p.1437-1449. Langues : Anglais (eng) in Autism Research > 16-7 (July 2023) . - p.1437-1449 Index. décimale : PER Périodiques Résumé : Abstract Autistic adults, as compared to non-autistic adults, have increased rates of nearly all medical and psychiatric conditions. Many of these conditions begin in childhood, although few longitudinal studies have been conducted to examine prevalence rates of these conditions from adolescence into early adulthood. In this study, we analyze the longitudinal trajectory of health conditions in autistic youth, compared to age and sex-matched non-autistic youth, transitioning from adolescence into early adulthood in a large integrated health care delivery system. The percent and modeled prevalence of common medical and psychiatric conditions increased from age 14 to 22 years, with autistic youth having a higher prevalence of most conditions than non-autistic youth. The most prevalent conditions in autistic youth at all ages were obesity, neurological disorders, anxiety, and ADHD. The prevalence of obesity and dyslipidemia rose at a faster rate in autistic youth compared to non-autistic youth. By age 22, autistic females showed a higher prevalence of all medical and psychiatric conditions compared to autistic males. Our findings emphasize the importance of screening for medical and psychiatric conditions in autistic youth, coupled with health education targeted at this population, to mitigate the development of adverse health outcomes in autistic adults. En ligne : https://doi.org/10.1002/aur.2960 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Medical Conditions in the First Years of Life Associated with Future Diagnosis of ASD in Children / Stacey E. ALEXEEFF in Journal of Autism and Developmental Disorders, 47-7 (July 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-7 (July 2017) . - p.2067-2079 Titre : Medical Conditions in the First Years of Life Associated with Future Diagnosis of ASD in Children Type de document : texte imprimé Auteurs : Stacey E. ALEXEEFF, Auteur ; Vincent YAU, Auteur ; Yinge QIAN, Auteur ; Meghan N. DAVIGNON, Auteur ; Frances LYNCH, Auteur ; Phillip M. CRAWFORD, Auteur ; Robert DAVIS, Auteur ; Lisa A. CROEN, Auteur Article en page(s) : p.2067-2079 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Comorbidity  Medical conditions Index. décimale : PER Périodiques Résumé : This study examines medical conditions diagnosed prior to the diagnosis of autism spectrum disorder (ASD). Using a matched case control design with 3911 ASD cases and 38,609 controls, we found that 38 out of 79 medical conditions were associated with increased ASD risk. Developmental delay, mental health, and neurology conditions had the strongest associations (ORs 2.0–23.3). Moderately strong associations were observed for nutrition, genetic, ear nose and throat, and sleep conditions (ORs 2.1–3.2). Using machine learning methods, we clustered children based on their medical conditions prior to ASD diagnosis and demonstrated ASD risk stratification. Our findings provide new evidence indicating that children with ASD have a disproportionate burden of certain medical conditions preceding ASD diagnosis. En ligne : https://doi.org/10.1007/s10803-017-3130-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=313 [article] Medical Conditions in the First Years of Life Associated with Future Diagnosis of ASD in Children [texte imprimé] / Stacey E. ALEXEEFF, Auteur ; Vincent YAU, Auteur ; Yinge QIAN, Auteur ; Meghan N. DAVIGNON, Auteur ; Frances LYNCH, Auteur ; Phillip M. CRAWFORD, Auteur ; Robert DAVIS, Auteur ; Lisa A. CROEN, Auteur . - p.2067-2079. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-7 (July 2017) . - p.2067-2079 Mots-clés : Autism spectrum disorder  Comorbidity  Medical conditions Index. décimale : PER Périodiques Résumé : This study examines medical conditions diagnosed prior to the diagnosis of autism spectrum disorder (ASD). Using a matched case control design with 3911 ASD cases and 38,609 controls, we found that 38 out of 79 medical conditions were associated with increased ASD risk. Developmental delay, mental health, and neurology conditions had the strongest associations (ORs 2.0–23.3). Moderately strong associations were observed for nutrition, genetic, ear nose and throat, and sleep conditions (ORs 2.1–3.2). Using machine learning methods, we clustered children based on their medical conditions prior to ASD diagnosis and demonstrated ASD risk stratification. Our findings provide new evidence indicating that children with ASD have a disproportionate burden of certain medical conditions preceding ASD diagnosis. En ligne : https://doi.org/10.1007/s10803-017-3130-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=313

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