Medical Conditions in the First Years of Life Associated with Future Diagnosis of ASD in Children / Stacey E. ALEXEEFF in Journal of Autism and Developmental Disorders, 47-7 (July 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-7 (July 2017) . - p.2067-2079 Titre : Medical Conditions in the First Years of Life Associated with Future Diagnosis of ASD in Children Type de document : Texte imprimé et/ou numérique Auteurs : Stacey E. ALEXEEFF, Auteur ; Vincent YAU, Auteur ; Yinge QIAN, Auteur ; Meghan N. DAVIGNON, Auteur ; Frances LYNCH, Auteur ; Phillip M. CRAWFORD, Auteur ; Robert DAVIS, Auteur ; Lisa A. CROEN, Auteur Article en page(s) : p.2067-2079 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Comorbidity  Medical conditions Index. décimale : PER Périodiques Résumé : This study examines medical conditions diagnosed prior to the diagnosis of autism spectrum disorder (ASD). Using a matched case control design with 3911 ASD cases and 38,609 controls, we found that 38 out of 79 medical conditions were associated with increased ASD risk. Developmental delay, mental health, and neurology conditions had the strongest associations (ORs 2.0–23.3). Moderately strong associations were observed for nutrition, genetic, ear nose and throat, and sleep conditions (ORs 2.1–3.2). Using machine learning methods, we clustered children based on their medical conditions prior to ASD diagnosis and demonstrated ASD risk stratification. Our findings provide new evidence indicating that children with ASD have a disproportionate burden of certain medical conditions preceding ASD diagnosis. En ligne : https://doi.org/10.1007/s10803-017-3130-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=313 [article] Medical Conditions in the First Years of Life Associated with Future Diagnosis of ASD in Children [Texte imprimé et/ou numérique] / Stacey E. ALEXEEFF, Auteur ; Vincent YAU, Auteur ; Yinge QIAN, Auteur ; Meghan N. DAVIGNON, Auteur ; Frances LYNCH, Auteur ; Phillip M. CRAWFORD, Auteur ; Robert DAVIS, Auteur ; Lisa A. CROEN, Auteur . - p.2067-2079. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-7 (July 2017) . - p.2067-2079 Mots-clés : Autism spectrum disorder  Comorbidity  Medical conditions Index. décimale : PER Périodiques Résumé : This study examines medical conditions diagnosed prior to the diagnosis of autism spectrum disorder (ASD). Using a matched case control design with 3911 ASD cases and 38,609 controls, we found that 38 out of 79 medical conditions were associated with increased ASD risk. Developmental delay, mental health, and neurology conditions had the strongest associations (ORs 2.0–23.3). Moderately strong associations were observed for nutrition, genetic, ear nose and throat, and sleep conditions (ORs 2.1–3.2). Using machine learning methods, we clustered children based on their medical conditions prior to ASD diagnosis and demonstrated ASD risk stratification. Our findings provide new evidence indicating that children with ASD have a disproportionate burden of certain medical conditions preceding ASD diagnosis. En ligne : https://doi.org/10.1007/s10803-017-3130-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=313

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