[article]
| Titre : |
Atypical sound discrimination in children with ASD as indicated by cortical ERPs |
| Type de document : |
texte imprimé |
| Auteurs : |
Aurélie BIDET-CAULET, Auteur ; Marianne LATINUS, Auteur ; Sylvie ROUX, Auteur ; Joëlle MALVY, Auteur ; Frédérique BONNET-BRILHAULT, Auteur ; Nicole BRUNEAU, Auteur |
| Article en page(s) : |
p.13 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Auditory Autism Development Ftpv Speech Voice |
| Index. décimale : |
PER Périodiques |
| Résumé : |
BACKGROUND: Individuals with autism spectrum disorder (ASD) show a relative indifference to the human voice. Accordingly, and contrarily to their typically developed peers, adults with autism do not show a preferential response to voices in the superior temporal sulcus; this lack of voice-specific response was previously linked to atypical processing of voices. In electroencephalography, a slow event-related potential (ERP) called the fronto-temporal positivity to voice (FTPV) is larger for vocal than for non-vocal sounds, resulting in a voice-sensitive response over right fronto-temporal sites. Here, we investigated the neurophysiological correlates of voice perception in children with and without ASD. METHODS: Sixteen children with autism and 16 age-matched typically developing children heard vocal (speech and non-speech) and non-vocal sounds while their electroencephalographic activity was recorded; overall IQ was smaller in the group of children with ASD. ERP amplitudes were compared using non-parametric statistical tests at each electrode and in successive 20-ms time windows. Within each group, differences between conditions were assessed using a non-parametric Quade test between 0 and 400 ms post-stimulus. Inter-group comparisons of ERP amplitudes were performed using non-paired Kruskal-Wallis tests between 140 and 180 ms post-stimulus. RESULTS: Typically developing children showed the classical voice-sensitive response over right fronto-temporal electrodes, for both speech and non-speech vocal sounds. Children with ASD did not show a preferential response to vocal sounds. Inter-group analysis showed no difference in the processing of vocal sounds, both speech and non-speech, but significant differences in the processing of non-vocal sounds over right fronto-temporal sites. CONCLUSIONS: Our results demonstrate a lack of voice-preferential response in children with autism spectrum disorders. In contrast to observations in adults with ASD, the lack of voice-preferential response was attributed to an atypical response to non-vocal sounds, which was overall more similar to the event-related potentials evoked by vocal sounds in both groups. This result suggests atypical maturation processes in ASD impeding the specialization of temporal regions in voice processing. |
| En ligne : |
http://dx.doi.org/10.1186/s11689-017-9194-9 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=350 |
in Journal of Neurodevelopmental Disorders > 9-1 (December 2017) . - p.13
[article] Atypical sound discrimination in children with ASD as indicated by cortical ERPs [texte imprimé] / Aurélie BIDET-CAULET, Auteur ; Marianne LATINUS, Auteur ; Sylvie ROUX, Auteur ; Joëlle MALVY, Auteur ; Frédérique BONNET-BRILHAULT, Auteur ; Nicole BRUNEAU, Auteur . - p.13. Langues : Anglais ( eng) in Journal of Neurodevelopmental Disorders > 9-1 (December 2017) . - p.13
| Mots-clés : |
Auditory Autism Development Ftpv Speech Voice |
| Index. décimale : |
PER Périodiques |
| Résumé : |
BACKGROUND: Individuals with autism spectrum disorder (ASD) show a relative indifference to the human voice. Accordingly, and contrarily to their typically developed peers, adults with autism do not show a preferential response to voices in the superior temporal sulcus; this lack of voice-specific response was previously linked to atypical processing of voices. In electroencephalography, a slow event-related potential (ERP) called the fronto-temporal positivity to voice (FTPV) is larger for vocal than for non-vocal sounds, resulting in a voice-sensitive response over right fronto-temporal sites. Here, we investigated the neurophysiological correlates of voice perception in children with and without ASD. METHODS: Sixteen children with autism and 16 age-matched typically developing children heard vocal (speech and non-speech) and non-vocal sounds while their electroencephalographic activity was recorded; overall IQ was smaller in the group of children with ASD. ERP amplitudes were compared using non-parametric statistical tests at each electrode and in successive 20-ms time windows. Within each group, differences between conditions were assessed using a non-parametric Quade test between 0 and 400 ms post-stimulus. Inter-group comparisons of ERP amplitudes were performed using non-paired Kruskal-Wallis tests between 140 and 180 ms post-stimulus. RESULTS: Typically developing children showed the classical voice-sensitive response over right fronto-temporal electrodes, for both speech and non-speech vocal sounds. Children with ASD did not show a preferential response to vocal sounds. Inter-group analysis showed no difference in the processing of vocal sounds, both speech and non-speech, but significant differences in the processing of non-vocal sounds over right fronto-temporal sites. CONCLUSIONS: Our results demonstrate a lack of voice-preferential response in children with autism spectrum disorders. In contrast to observations in adults with ASD, the lack of voice-preferential response was attributed to an atypical response to non-vocal sounds, which was overall more similar to the event-related potentials evoked by vocal sounds in both groups. This result suggests atypical maturation processes in ASD impeding the specialization of temporal regions in voice processing. |
| En ligne : |
http://dx.doi.org/10.1186/s11689-017-9194-9 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=350 |
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Atypical sound discrimination in children with ASD as indicated by cortical ERPs in Journal of Neurodevelopmental Disorders, 9-1 (December 2017)
