Aging with elevated autistic traits: Cognitive functioning among older adults with the broad autism phenotype / Gavin R. STEWART in Research in Autism Spectrum Disorders, 54 (October 2018)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 54 (October 2018) . - p.27-36 Titre : Aging with elevated autistic traits: Cognitive functioning among older adults with the broad autism phenotype Type de document : texte imprimé Auteurs : Gavin R. STEWART, Auteur ; Rebecca A. CHARLTON, Auteur ; Gregory L. WALLACE, Auteur Article en page(s) : p.27-36 Langues : Anglais (eng) Mots-clés : Aging  Broad autism phenotype  Executive function Index. décimale : PER Périodiques Résumé : Background Little is known about the impact of aging with autism spectrum disorder (ASD) on cognition. As a first step in addressing this gap in our knowledge, the current study examined cognitive functioning among older adults with elevated, but subclinical levels of autistic traits (i.e., the Broad Autism Phenotype; BAP) compared to older adults without the BAP. Method Forty older adults (aged 60–91, M = 73 years) were recruited and classified as meeting criteria for the BAP (n = 20) or not (control older adults, COA; n = 20). Different components of executive function as well as episodic memory were measured using standardized performance-based neuropsychological assessments in addition to a self-report questionnaire of executive function difficulties. Results Despite no differences in age, sex ratio, educational history or IQ, the BAP group demonstrated poorer performance on measures of executive function and episodic memory compared to the COA group. The BAP group also self-reported more executive function difficulties in everyday settings. Moreover, differences in working memory and attentional shifting were maintained after accounting for the influences of IQ and both depression and anxiety symptoms. Conclusions These findings suggest that aging with the BAP confers additional risk to cognitive function for older adults. As the BAP forms a bridge in the continuum from typical to atypical levels of autistic traits, these findings suggest that individuals with ASD might also incur cognitive costs as they age into older adulthood. En ligne : https://doi.org/10.1016/j.rasd.2018.06.009 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 [article] Aging with elevated autistic traits: Cognitive functioning among older adults with the broad autism phenotype [texte imprimé] / Gavin R. STEWART, Auteur ; Rebecca A. CHARLTON, Auteur ; Gregory L. WALLACE, Auteur . - p.27-36. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 54 (October 2018) . - p.27-36 Mots-clés : Aging  Broad autism phenotype  Executive function Index. décimale : PER Périodiques Résumé : Background Little is known about the impact of aging with autism spectrum disorder (ASD) on cognition. As a first step in addressing this gap in our knowledge, the current study examined cognitive functioning among older adults with elevated, but subclinical levels of autistic traits (i.e., the Broad Autism Phenotype; BAP) compared to older adults without the BAP. Method Forty older adults (aged 60–91, M = 73 years) were recruited and classified as meeting criteria for the BAP (n = 20) or not (control older adults, COA; n = 20). Different components of executive function as well as episodic memory were measured using standardized performance-based neuropsychological assessments in addition to a self-report questionnaire of executive function difficulties. Results Despite no differences in age, sex ratio, educational history or IQ, the BAP group demonstrated poorer performance on measures of executive function and episodic memory compared to the COA group. The BAP group also self-reported more executive function difficulties in everyday settings. Moreover, differences in working memory and attentional shifting were maintained after accounting for the influences of IQ and both depression and anxiety symptoms. Conclusions These findings suggest that aging with the BAP confers additional risk to cognitive function for older adults. As the BAP forms a bridge in the continuum from typical to atypical levels of autistic traits, these findings suggest that individuals with ASD might also incur cognitive costs as they age into older adulthood. En ligne : https://doi.org/10.1016/j.rasd.2018.06.009 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368

Autisme : une conceptualisation en évolution / Gavin R. STEWART in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E., 188 (Mars 2024)

Public ISBD [article]  inApproche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E. > 188 (Mars 2024) . - p.53-61 Titre : Autisme : une conceptualisation en évolution Type de document : texte imprimé Auteurs : Gavin R. STEWART, Auteur ; Francesca HAPPE, Auteur Année de publication : 2024 Article en page(s) : p.53-61 Langues : Français (fre) Mots-clés : Troubles du spectre autistique  Syndrome d'Asperger- Troubles neurodéveloppementaux  Critères diagnostiques  Neurodiversité Index. décimale : PER Périodiques Résumé : La conceptualisation de l'autisme a considérablement évolué au cours des dernières décennies. Dans cet article de synthèse, nous nous concentrons sur plusieurs domaines où notre compréhension de l'autisme a changé : 1. d’une définition « étroite » à des critères diagnostiques « larges » ; 2. d'une condition rare à une condition relativement courante, bien que probablement encore sous-reconnue chez les femmes et les personnes âgées; 3. d'une condition diagnostiquée principalement chez les hommes à une identification, désormais, chez les personnes de tous genres ; 4. d'un état qui touche les enfants à une condition tout au long de la vie; 5. d'une manifestation discrète et distincte à une vision dimensionnelle; 6. d'une seule entité à de nombreux « autismes », et une condition composite ou fractionnable ; 7. d'une focalisation sur l'autisme « pur » à a reconnaissance que la complexité et la comorbidité sont la norme ; 8. de la conceptualisation de l'autisme uniquement comme un trouble du développement à la reconnaissance d'une perspective de neurodiversité, opérationnalisée dans des modèles de recherche participative. Nous explorons également les opportunités pour que la recherche devienne plus généralisable, y compris clans un contexte mondial, et formulons des suggestions pour des domaines actuellement négligés dans la recherche sur l'autisme. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=535 [article] Autisme : une conceptualisation en évolution [texte imprimé] / Gavin R. STEWART, Auteur ; Francesca HAPPE, Auteur . - 2024 . - p.53-61. Langues : Français (fre) in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E. > 188 (Mars 2024) . - p.53-61 Mots-clés : Troubles du spectre autistique  Syndrome d'Asperger- Troubles neurodéveloppementaux  Critères diagnostiques  Neurodiversité Index. décimale : PER Périodiques Résumé : La conceptualisation de l'autisme a considérablement évolué au cours des dernières décennies. Dans cet article de synthèse, nous nous concentrons sur plusieurs domaines où notre compréhension de l'autisme a changé : 1. d’une définition « étroite » à des critères diagnostiques « larges » ; 2. d'une condition rare à une condition relativement courante, bien que probablement encore sous-reconnue chez les femmes et les personnes âgées; 3. d'une condition diagnostiquée principalement chez les hommes à une identification, désormais, chez les personnes de tous genres ; 4. d'un état qui touche les enfants à une condition tout au long de la vie; 5. d'une manifestation discrète et distincte à une vision dimensionnelle; 6. d'une seule entité à de nombreux « autismes », et une condition composite ou fractionnable ; 7. d'une focalisation sur l'autisme « pur » à a reconnaissance que la complexité et la comorbidité sont la norme ; 8. de la conceptualisation de l'autisme uniquement comme un trouble du développement à la reconnaissance d'une perspective de neurodiversité, opérationnalisée dans des modèles de recherche participative. Nous explorons également les opportunités pour que la recherche devienne plus généralisable, y compris clans un contexte mondial, et formulons des suggestions pour des domaines actuellement négligés dans la recherche sur l'autisme. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=535

"Bigger lows, but higher highs": A qualitative exploration of the similarities and differences in quality of life of middle-aged and older autistic and non-autistic adults / David HERSHMAN ; Rebecca A. CHARLTON ; Francesca HAPPE ; Gavin R. STEWART in Research in Autism, 123 (May 2025)  

Public ISBD [article]  inResearch in Autism > 123 (May 2025) . - 202533 Titre : "Bigger lows, but higher highs": A qualitative exploration of the similarities and differences in quality of life of middle-aged and older autistic and non-autistic adults Type de document : texte imprimé Auteurs : David HERSHMAN, Auteur ; Rebecca A. CHARLTON, Auteur ; Francesca HAPPE, Auteur ; Gavin R. STEWART, Auteur Article en page(s) : 202533 Langues : Anglais (eng) Mots-clés : Autism  Quality of life  Midlife  Older age  Qualitative Index. décimale : PER Périodiques Résumé : Background Autistic adults often report lower subjective quality of life (QoL) than non-autistic adults. Despite older age also often being associated with lower QoL, little is known about the first-hand experiences of, and influences on, QoL for middle-aged and older autistic adults compared with their non-autistic peers. Method Thirty-three participants (autistic n = 15, non-autistic n = 18) aged 50-89 years completed semi-structured interviewed that explored their QoL. Responses were thematically analysed, and themes were compared to identify similarities and differences between groups. Results Both autistic and non-autistic groups reported similar QoL experiences, but with subtle differences. Social support from family and friends was important for both groups. Both noted shrinking social networks with age, but the non-autistic group was often less satisfied with their social lives. Concerns about health and sleep changes were common, but autistic participants often mentioned persistent mental health issues affecting their wellbeing. Autistic individuals also highlighted sensory sensitivities and difficulties with change. Receiving their autism diagnosis was significant for autistic participants, aiding self-acceptance. Acceptance of age-related changes was common in both groups, but the autistic group was more willing to seek support, while the non-autistic group often saw asking for help as losing their independence. Conclusions These findings highlight similarities and differences in aspects relevant to QoL for middle-aged and older autistic and non-autistic adults. While many similarities were found, the autistic group reported subtle differences in their experiences. Experiences such as social connectedness and coping with change could be targeted to improve the QoL of ageing autistic adults. En ligne : https://doi.org/10.1016/j.reia.2025.202533 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=555 [article] "Bigger lows, but higher highs": A qualitative exploration of the similarities and differences in quality of life of middle-aged and older autistic and non-autistic adults [texte imprimé] / David HERSHMAN, Auteur ; Rebecca A. CHARLTON, Auteur ; Francesca HAPPE, Auteur ; Gavin R. STEWART, Auteur . - 202533. Langues : Anglais (eng) in Research in Autism > 123 (May 2025) . - 202533 Mots-clés : Autism  Quality of life  Midlife  Older age  Qualitative Index. décimale : PER Périodiques Résumé : Background Autistic adults often report lower subjective quality of life (QoL) than non-autistic adults. Despite older age also often being associated with lower QoL, little is known about the first-hand experiences of, and influences on, QoL for middle-aged and older autistic adults compared with their non-autistic peers. Method Thirty-three participants (autistic n = 15, non-autistic n = 18) aged 50-89 years completed semi-structured interviewed that explored their QoL. Responses were thematically analysed, and themes were compared to identify similarities and differences between groups. Results Both autistic and non-autistic groups reported similar QoL experiences, but with subtle differences. Social support from family and friends was important for both groups. Both noted shrinking social networks with age, but the non-autistic group was often less satisfied with their social lives. Concerns about health and sleep changes were common, but autistic participants often mentioned persistent mental health issues affecting their wellbeing. Autistic individuals also highlighted sensory sensitivities and difficulties with change. Receiving their autism diagnosis was significant for autistic participants, aiding self-acceptance. Acceptance of age-related changes was common in both groups, but the autistic group was more willing to seek support, while the non-autistic group often saw asking for help as losing their independence. Conclusions These findings highlight similarities and differences in aspects relevant to QoL for middle-aged and older autistic and non-autistic adults. While many similarities were found, the autistic group reported subtle differences in their experiences. Experiences such as social connectedness and coping with change could be targeted to improve the QoL of ageing autistic adults. En ligne : https://doi.org/10.1016/j.reia.2025.202533 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=555

A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression / David MASON in Journal of Autism and Developmental Disorders, 51-9 (September 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-9 (September 2021) . - p.3165-3179 Titre : A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression Type de document : texte imprimé Auteurs : David MASON, Auteur ; Simone J. CAPP, Auteur ; Gavin R. STEWART, Auteur ; Matthew J. KEMPTON, Auteur ; Karen GLASER, Auteur ; Patricia HOWLIN, Auteur ; Francesca HAPPE, Auteur Article en page(s) : p.3165-3179 Langues : Anglais (eng) Mots-clés : Adult  Autism Spectrum Disorder  Autistic Disorder  Humans  Outcome Assessment, Health Care  Autism spectrum disorder  Functioning  Meta-analysis  Outcome Index. décimale : PER Périodiques Résumé : Longitudinal studies have generally reported poor outcomes in adulthood for the majority of individuals (c.50-60%) with autism. Several factors putatively predict outcome (e.g. IQ), but findings remain mixed. This paper presents an updated meta-analysis of autism outcome studies and extends previous findings with additional analyses (including meta-regression). A total of 4088 records was screened and 18 studies, involving 1199 individuals, were included in the quantitative analysis. Estimated percentages indicated that 20.0% of participants were rated as having a good outcome, 26.6% a fair outcome, and 49.3% a poor outcome. Meta-regression indicated that lower IQ in adulthood was predictive of poor outcome; other meta-regression models did not survive correction for multiple comparisons. Overall, outcomes for autistic people are on average poor, and higher IQ appears to be protective against having a poor outcome. The limitations of current constructs of outcome are discussed. En ligne : http://dx.doi.org/10.1007/s10803-020-04763-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453 [article] A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression [texte imprimé] / David MASON, Auteur ; Simone J. CAPP, Auteur ; Gavin R. STEWART, Auteur ; Matthew J. KEMPTON, Auteur ; Karen GLASER, Auteur ; Patricia HOWLIN, Auteur ; Francesca HAPPE, Auteur . - p.3165-3179. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-9 (September 2021) . - p.3165-3179 Mots-clés : Adult  Autism Spectrum Disorder  Autistic Disorder  Humans  Outcome Assessment, Health Care  Autism spectrum disorder  Functioning  Meta-analysis  Outcome Index. décimale : PER Périodiques Résumé : Longitudinal studies have generally reported poor outcomes in adulthood for the majority of individuals (c.50-60%) with autism. Several factors putatively predict outcome (e.g. IQ), but findings remain mixed. This paper presents an updated meta-analysis of autism outcome studies and extends previous findings with additional analyses (including meta-regression). A total of 4088 records was screened and 18 studies, involving 1199 individuals, were included in the quantitative analysis. Estimated percentages indicated that 20.0% of participants were rated as having a good outcome, 26.6% a fair outcome, and 49.3% a poor outcome. Meta-regression indicated that lower IQ in adulthood was predictive of poor outcome; other meta-regression models did not survive correction for multiple comparisons. Overall, outcomes for autistic people are on average poor, and higher IQ appears to be protective against having a poor outcome. The limitations of current constructs of outcome are discussed. En ligne : http://dx.doi.org/10.1007/s10803-020-04763-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453

Self-harm and Suicidality Experiences of Middle-Age and Older Adults With vs. Without High Autistic Traits / Gavin R. STEWART in Journal of Autism and Developmental Disorders, 53-8 (August 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-8 (August 2023) . - p.3034-3046 Titre : Self-harm and Suicidality Experiences of Middle-Age and Older Adults With vs. Without High Autistic Traits Type de document : texte imprimé Auteurs : Gavin R. STEWART, Auteur ; Anne CORBETT, Auteur ; Clive BALLARD, Auteur ; Byron CREESE, Auteur ; Dag AARSLAND, Auteur ; Adam HAMPSHIRE, Auteur ; Rebecca A. CHARLTON, Auteur ; Francesca HAPPE, Auteur Article en page(s) : p.3034-3046 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Suicide has been identified as a leading cause of premature death in autistic populations. Elevated autistic traits have also been associated with higher rates of self-harm, suicidal ideation, and suicidal self-harm in the general population, but this has yet to be examined in older age. Using baseline cross-sectional data from the PROTECT study, middle-age and older adults with high autistic traits (n 276) had significantly higher rates of suicidal ideation, deliberate self-harm, and suicidal self-harm than an age/sex-matched comparison group (n 10,495). These differences represented a 5- to 6-fold increase in likelihood for self-harming and suicidality. These findings, which remained when controlling for depression symptoms, suggest that middle-age and older adults with high autistic traits may be particularly at risk of self-harm and suicidal behaviours. En ligne : https://doi.org/10.1007/s10803-022-05595-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508 [article] Self-harm and Suicidality Experiences of Middle-Age and Older Adults With vs. Without High Autistic Traits [texte imprimé] / Gavin R. STEWART, Auteur ; Anne CORBETT, Auteur ; Clive BALLARD, Auteur ; Byron CREESE, Auteur ; Dag AARSLAND, Auteur ; Adam HAMPSHIRE, Auteur ; Rebecca A. CHARLTON, Auteur ; Francesca HAPPE, Auteur . - p.3034-3046. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-8 (August 2023) . - p.3034-3046 Index. décimale : PER Périodiques Résumé : Suicide has been identified as a leading cause of premature death in autistic populations. Elevated autistic traits have also been associated with higher rates of self-harm, suicidal ideation, and suicidal self-harm in the general population, but this has yet to be examined in older age. Using baseline cross-sectional data from the PROTECT study, middle-age and older adults with high autistic traits (n 276) had significantly higher rates of suicidal ideation, deliberate self-harm, and suicidal self-harm than an age/sex-matched comparison group (n 10,495). These differences represented a 5- to 6-fold increase in likelihood for self-harming and suicidality. These findings, which remained when controlling for depression symptoms, suggest that middle-age and older adults with high autistic traits may be particularly at risk of self-harm and suicidal behaviours. En ligne : https://doi.org/10.1007/s10803-022-05595-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508

Sleep problems and mental health difficulties in older adults who endorse high autistic traits / Gavin R. STEWART in Research in Autism Spectrum Disorders, 77 (September 2020)  

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The Mental and Physical Health of Older Adults With a Genetic Predisposition for Autism / Gavin R. STEWART in Autism Research, 13-4 (April 2020)  

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Theory of Mind Mediates the Association Between Autistic Traits and Social Isolation in Middle-Aged and Older Adults / Clemie DALE ; Francesca HAPPE ; Gavin R. STEWART in Autism Research, 18-6 (June 2025)  

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Theory of mind performance in younger and older adults with elevated autistic traits / Gavin R. STEWART in Autism Research, 13-5 (May 2020)  

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