Correction to: Serum Ischemia-Modified Albumin Levels, Myeloperoxidase Activity and Peripheral Blood Mononuclear Cells in Autism Spectrum Disorder (ASD) / Mehmet Fatih CEYLAN in Journal of Autism and Developmental Disorders, 51-7 (July 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2518 Titre : Correction to: Serum Ischemia-Modified Albumin Levels, Myeloperoxidase Activity and Peripheral Blood Mononuclear Cells in Autism Spectrum Disorder (ASD) Type de document : Texte imprimé et/ou numérique Auteurs : Mehmet Fatih CEYLAN, Auteur ; S. TURAL HESAPCIOGLU, Auteur ; C. P. YAVAS, Auteur ; A. SENAT, Auteur ; O. EREL, Auteur Article en page(s) : p.2518 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-020-04834-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 [article] Correction to: Serum Ischemia-Modified Albumin Levels, Myeloperoxidase Activity and Peripheral Blood Mononuclear Cells in Autism Spectrum Disorder (ASD) [Texte imprimé et/ou numérique] / Mehmet Fatih CEYLAN, Auteur ; S. TURAL HESAPCIOGLU, Auteur ; C. P. YAVAS, Auteur ; A. SENAT, Auteur ; O. EREL, Auteur . - p.2518. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2518 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-020-04834-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452

Increased Serum Levels of Epidermal Growth Factor in Children with Autism / Elvan ISERI in Journal of Autism and Developmental Disorders, 41-2 (February 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-2 (February 2011) . - p.237-241 Titre : Increased Serum Levels of Epidermal Growth Factor in Children with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Elvan ISERI, Auteur ; Esra GUNEY, Auteur ; Mehmet Fatih CEYLAN, Auteur ; Ayşegül YUCEL, Auteur ; Arzu ARAL, Auteur ; Sahin BODUR, Auteur ; Sahnur SENER, Auteur Année de publication : 2011 Article en page(s) : p.237-241 Langues : Anglais (eng) Mots-clés : Autism  Developmental disorders  Epidermal growth factor  Growth factors Index. décimale : PER Périodiques Résumé : The etiology of autism is unclear, however autism is considered as a multifactorial disorder that is influenced by neurological, environmental, immunological and genetic factors. Growth factors, including epidermal growth factor (EGF), play an important role in the celluler proliferation and the differentiation of the central and peripheral nervous system. In this study we hypothesized that EGF may play a role in the pathophysiology of autism and examined serum EGF levels in children with autism. We measured serum levels of EGF in the 27 autistic children and 28 age- matched normal controls. The serum levels of EGF in the subjects with autism were significantly higher than those of normal control subjects. However, there were no correlations between serum EGF levels and clinical variables in the subjects with autism. This is the first report demonstrating the increased serum levels of EGF in children with autism. This study suggests that increased levels of EGF might have an importance in the pathophysiology of autism. En ligne : http://dx.doi.org/10.1007/s10803-010-1046-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=117 [article] Increased Serum Levels of Epidermal Growth Factor in Children with Autism [Texte imprimé et/ou numérique] / Elvan ISERI, Auteur ; Esra GUNEY, Auteur ; Mehmet Fatih CEYLAN, Auteur ; Ayşegül YUCEL, Auteur ; Arzu ARAL, Auteur ; Sahin BODUR, Auteur ; Sahnur SENER, Auteur . - 2011 . - p.237-241. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-2 (February 2011) . - p.237-241 Mots-clés : Autism  Developmental disorders  Epidermal growth factor  Growth factors Index. décimale : PER Périodiques Résumé : The etiology of autism is unclear, however autism is considered as a multifactorial disorder that is influenced by neurological, environmental, immunological and genetic factors. Growth factors, including epidermal growth factor (EGF), play an important role in the celluler proliferation and the differentiation of the central and peripheral nervous system. In this study we hypothesized that EGF may play a role in the pathophysiology of autism and examined serum EGF levels in children with autism. We measured serum levels of EGF in the 27 autistic children and 28 age- matched normal controls. The serum levels of EGF in the subjects with autism were significantly higher than those of normal control subjects. However, there were no correlations between serum EGF levels and clinical variables in the subjects with autism. This is the first report demonstrating the increased serum levels of EGF in children with autism. This study suggests that increased levels of EGF might have an importance in the pathophysiology of autism. En ligne : http://dx.doi.org/10.1007/s10803-010-1046-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=117

Olanzapine, risperidone, and aripiprazole use in children and adolescents with Autism Spectrum Disorders / Selma TURAL HESAPCIOGLU in Research in Autism Spectrum Disorders, 72 (April 2020)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 72 (April 2020) . - p.101520 Titre : Olanzapine, risperidone, and aripiprazole use in children and adolescents with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Selma TURAL HESAPCIOGLU, Auteur ; Mehmet Fatih CEYLAN, Auteur ; Meryem KASAK, Auteur ; Cansu P?nar SEN, Auteur Article en page(s) : p.101520 Langues : Anglais (eng) Mots-clés : Antipsychotic  Aripiprazole  Autism Spectrum Disorders  Irritability  Olanzapine  Risperidone Index. décimale : PER Périodiques Résumé : Background The aim of this study is to examine the use of olanzapine, risperidone and aripiprazole in autism spectrum disorders (ASD) in terms of their effects and side effects. Methods ASD patients that had been initiated to be treated with one of the three antipsychotics that continued for a minimum of eight weeks were included in the study, retrospectively. The participants were recruited with 20 olanzapine using patients (2.5?10 mg/day) in comparison with 42 risperidone (1?4 mg/day) and 40 aripiprazole (3?15 mg/day) using patients that are using the matched equivalent chlorpromazine doses of the antipsychotics between the same time period. Results All three antipsychotics significantly decreased all of the ABC subscales scores in eight weeks. Sleepiness/sedation, increased duration of sleep, and weight gain were the most common side effects of the three antipsychotics and they were more frequent with olanzapine than with the others (X2 = 26.9, p < 0.0001; X2 = 20.8, p < 0.0001; X2 = 8.4, p = 0.01, respectively). Discussion Our results reveal that risperidone, aripiprazole, and olanzapine are effective in treatment of irritability, hyperactivity, social withdrawal, stereotypy, and inappropriate speech in ASD. But the side effects are more frequent with olanzapine and it should be considered when choosing antipsychotics for ASD. En ligne : https://doi.org/10.1016/j.rasd.2020.101520 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421 [article] Olanzapine, risperidone, and aripiprazole use in children and adolescents with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Selma TURAL HESAPCIOGLU, Auteur ; Mehmet Fatih CEYLAN, Auteur ; Meryem KASAK, Auteur ; Cansu P?nar SEN, Auteur . - p.101520. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 72 (April 2020) . - p.101520 Mots-clés : Antipsychotic  Aripiprazole  Autism Spectrum Disorders  Irritability  Olanzapine  Risperidone Index. décimale : PER Périodiques Résumé : Background The aim of this study is to examine the use of olanzapine, risperidone and aripiprazole in autism spectrum disorders (ASD) in terms of their effects and side effects. Methods ASD patients that had been initiated to be treated with one of the three antipsychotics that continued for a minimum of eight weeks were included in the study, retrospectively. The participants were recruited with 20 olanzapine using patients (2.5?10 mg/day) in comparison with 42 risperidone (1?4 mg/day) and 40 aripiprazole (3?15 mg/day) using patients that are using the matched equivalent chlorpromazine doses of the antipsychotics between the same time period. Results All three antipsychotics significantly decreased all of the ABC subscales scores in eight weeks. Sleepiness/sedation, increased duration of sleep, and weight gain were the most common side effects of the three antipsychotics and they were more frequent with olanzapine than with the others (X2 = 26.9, p < 0.0001; X2 = 20.8, p < 0.0001; X2 = 8.4, p = 0.01, respectively). Discussion Our results reveal that risperidone, aripiprazole, and olanzapine are effective in treatment of irritability, hyperactivity, social withdrawal, stereotypy, and inappropriate speech in ASD. But the side effects are more frequent with olanzapine and it should be considered when choosing antipsychotics for ASD. En ligne : https://doi.org/10.1016/j.rasd.2020.101520 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421

Serum Ischemia-Modified Albumin Levels, Myeloperoxidase Activity and Peripheral Blood Mononuclear cells in Autism Spectrum Disorder (ASD) / Mehmet Fatih CEYLAN in Journal of Autism and Developmental Disorders, 51-7 (July 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2511-2517 Titre : Serum Ischemia-Modified Albumin Levels, Myeloperoxidase Activity and Peripheral Blood Mononuclear cells in Autism Spectrum Disorder (ASD) Type de document : Texte imprimé et/ou numérique Auteurs : Mehmet Fatih CEYLAN, Auteur ; S. TURAL HESAPCIOGLU, Auteur ; C. P. YAVAS, Auteur ; A. SENAT, Auteur ; O. EREL, Auteur Article en page(s) : p.2511-2517 Langues : Anglais (eng) Mots-clés : Adolescent  Adult  Autism Spectrum Disorder/blood  Biomarkers/blood  Case-Control Studies  Child  Child, Preschool  Humans  Leukocytes, Mononuclear  Male  Monocytes/immunology  Oxidative Stress  Peroxidase/blood  Serum Albumin  Serum Albumin, Human  Asd  Autism spectrum disorder  Ima  Ischemia-modified albumin  Lymphocytes  Monocytes  Myeloperoxidase  Neutrophils Index. décimale : PER Périodiques Résumé : Genetic, neurobiological, neurochemical, environmental factors and their interactions contribute to autism phenotypes. Blood from 48 (age range: 4-17) autism spectrum disorder diagnosed patients (ASD) and 38 age- and gender-matched healthy control subjects was analyzed for numbers of neutrophils, lymphocytes, monocytes, albumin, serum Ischemia-Modified Albumin (IMA) levels and myeloperoxidase activity. The serum IMA levels, myeloperoxidase activity and peripheral blood mononuclear cells count were significantly higher in ASD cases than in the control subjects. There were no significant differences in albumin levels between the patient and control groups. These results suggest that the immune system, oxidative stress and myeloperoxidase activity may be activated in ASD. There is a clinical benefit from the early detection of ASD using myeloperoxidase activity, IMA levels and monocyte counts. En ligne : http://dx.doi.org/10.1007/s10803-020-04740-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 [article] Serum Ischemia-Modified Albumin Levels, Myeloperoxidase Activity and Peripheral Blood Mononuclear cells in Autism Spectrum Disorder (ASD) [Texte imprimé et/ou numérique] / Mehmet Fatih CEYLAN, Auteur ; S. TURAL HESAPCIOGLU, Auteur ; C. P. YAVAS, Auteur ; A. SENAT, Auteur ; O. EREL, Auteur . - p.2511-2517. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2511-2517 Mots-clés : Adolescent  Adult  Autism Spectrum Disorder/blood  Biomarkers/blood  Case-Control Studies  Child  Child, Preschool  Humans  Leukocytes, Mononuclear  Male  Monocytes/immunology  Oxidative Stress  Peroxidase/blood  Serum Albumin  Serum Albumin, Human  Asd  Autism spectrum disorder  Ima  Ischemia-modified albumin  Lymphocytes  Monocytes  Myeloperoxidase  Neutrophils Index. décimale : PER Périodiques Résumé : Genetic, neurobiological, neurochemical, environmental factors and their interactions contribute to autism phenotypes. Blood from 48 (age range: 4-17) autism spectrum disorder diagnosed patients (ASD) and 38 age- and gender-matched healthy control subjects was analyzed for numbers of neutrophils, lymphocytes, monocytes, albumin, serum Ischemia-Modified Albumin (IMA) levels and myeloperoxidase activity. The serum IMA levels, myeloperoxidase activity and peripheral blood mononuclear cells count were significantly higher in ASD cases than in the control subjects. There were no significant differences in albumin levels between the patient and control groups. These results suggest that the immune system, oxidative stress and myeloperoxidase activity may be activated in ASD. There is a clinical benefit from the early detection of ASD using myeloperoxidase activity, IMA levels and monocyte counts. En ligne : http://dx.doi.org/10.1007/s10803-020-04740-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452

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