Heterogeneity and imbalance of reading profiles in Autism Spectrum Disorders / Juan LIU in Research in Autism Spectrum Disorders, 100 (February 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 100 (February 2023) . - 102088 Titre : Heterogeneity and imbalance of reading profiles in Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Juan LIU, Auteur ; Ying WANG, Auteur ; Li YI, Auteur Article en page(s) : 102088 Langues : Anglais (eng) Mots-clés : Hyperlexia  Word decoding  Listening comprehension  Morphological awareness  Orthographic awareness Index. décimale : PER Périodiques Résumé : This study aimed to identify distinct reading profiles in 4 “11-year-old Chinese autistic and neurotypical (NT) children and to examine the unique characteristics of each group. Forty-five autistic children and 45 NT comparisons matched on nonverbal IQ and age were assessed in a comprehensive reading battery including word reading, listening comprehension, and reading-related language skills. Using latent profile analysis, four reading profiles of autistic children emerged: readers with good decoding and listening comprehension skills (GDGL, 33.3 %), good decoders with poor listening comprehension skills (GDPL, 35.7 %), readers with average decoding and listening comprehension skills (ADAL, 20 %), and readers with poor decoding and listening comprehension skills (PDPL, 20 %). Furthermore, the results indicated an imbalanced pattern of reading profiles with over 50 % of autistic children performing well in certain reading abilities but poorly in other skills. The findings highlight the urgent need for designing individualized reading supports for autistic children. En ligne : https://doi.org/10.1016/j.rasd.2022.102088 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=491 [article] Heterogeneity and imbalance of reading profiles in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Juan LIU, Auteur ; Ying WANG, Auteur ; Li YI, Auteur . - 102088. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 100 (February 2023) . - 102088 Mots-clés : Hyperlexia  Word decoding  Listening comprehension  Morphological awareness  Orthographic awareness Index. décimale : PER Périodiques Résumé : This study aimed to identify distinct reading profiles in 4 “11-year-old Chinese autistic and neurotypical (NT) children and to examine the unique characteristics of each group. Forty-five autistic children and 45 NT comparisons matched on nonverbal IQ and age were assessed in a comprehensive reading battery including word reading, listening comprehension, and reading-related language skills. Using latent profile analysis, four reading profiles of autistic children emerged: readers with good decoding and listening comprehension skills (GDGL, 33.3 %), good decoders with poor listening comprehension skills (GDPL, 35.7 %), readers with average decoding and listening comprehension skills (ADAL, 20 %), and readers with poor decoding and listening comprehension skills (PDPL, 20 %). Furthermore, the results indicated an imbalanced pattern of reading profiles with over 50 % of autistic children performing well in certain reading abilities but poorly in other skills. The findings highlight the urgent need for designing individualized reading supports for autistic children. En ligne : https://doi.org/10.1016/j.rasd.2022.102088 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=491

Maternal Exposure to Pesticides and Risk of Autism Spectrum Disorders in Offspring: A Meta-analysis / Li WANG in Journal of Autism and Developmental Disorders, 52-4 (April 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1640-1651 Titre : Maternal Exposure to Pesticides and Risk of Autism Spectrum Disorders in Offspring: A Meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Li WANG, Auteur ; Shiming TANG, Auteur ; Songjie WU, Auteur ; Lihua YAO, Auteur ; Dezhen SU, Auteur ; Ying WANG, Auteur Article en page(s) : p.1640-1651 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/chemically induced/epidemiology  Female  Humans  Maternal Exposure/statistics & numerical data  Pesticides/toxicity  Self Report  Autism  Meta-analysis  Pesticides  Risk factor Index. décimale : PER Périodiques Résumé : This meta-analysis was conducted to estimate the overall association between maternal exposure to pesticides and risk of ASD in offspring. PubMed, EMBASE, Web of Science, and the PsycINFO were searched until December 30, 2020 to include eligible studies. Eight studies with 50,426 participants, 5810 of whom had ASD, were involved in the study. Overall, the summary OR (95% confidence interval) of ASDs in offspring for maternal exposure to pesticide estimated by residential proximity measures and self-report was 1.88 (1.10-3.20). However, maternal exposure to pesticide measured by biomarkers was not associated with an increased risk of ASDs (pooled OR 1.13; 95% CI 0.83-1.54). Further well-designed studies are needed to confirm our findings. En ligne : http://dx.doi.org/10.1007/s10803-021-05063-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475 [article] Maternal Exposure to Pesticides and Risk of Autism Spectrum Disorders in Offspring: A Meta-analysis [Texte imprimé et/ou numérique] / Li WANG, Auteur ; Shiming TANG, Auteur ; Songjie WU, Auteur ; Lihua YAO, Auteur ; Dezhen SU, Auteur ; Ying WANG, Auteur . - p.1640-1651. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1640-1651 Mots-clés : Autism Spectrum Disorder/chemically induced/epidemiology  Female  Humans  Maternal Exposure/statistics & numerical data  Pesticides/toxicity  Self Report  Autism  Meta-analysis  Pesticides  Risk factor Index. décimale : PER Périodiques Résumé : This meta-analysis was conducted to estimate the overall association between maternal exposure to pesticides and risk of ASD in offspring. PubMed, EMBASE, Web of Science, and the PsycINFO were searched until December 30, 2020 to include eligible studies. Eight studies with 50,426 participants, 5810 of whom had ASD, were involved in the study. Overall, the summary OR (95% confidence interval) of ASDs in offspring for maternal exposure to pesticide estimated by residential proximity measures and self-report was 1.88 (1.10-3.20). However, maternal exposure to pesticide measured by biomarkers was not associated with an increased risk of ASDs (pooled OR 1.13; 95% CI 0.83-1.54). Further well-designed studies are needed to confirm our findings. En ligne : http://dx.doi.org/10.1007/s10803-021-05063-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475

Maternal Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Risk for Autism Spectrum Disorders in Offspring: A Meta-analysis / Zhixian ZHU in Journal of Autism and Developmental Disorders, 50-8 (August 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-8 (August 2020) . - p.2852-2859 Titre : Maternal Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Risk for Autism Spectrum Disorders in Offspring: A Meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Zhixian ZHU, Auteur ; Shiming TANG, Auteur ; Xiaopeng DENG, Auteur ; Ying WANG, Auteur Article en page(s) : p.2852-2859 Langues : Anglais (eng) Mots-clés : Autism  Meta-analysis  Rheumatoid arthritis  Systemic lupus erythematosus Index. décimale : PER Périodiques Résumé : This study assessed the relationships between maternal systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA) and risk for autism spectrum disorders (ASDs) in offspring. Seven observational studies, including 25,005 ASD cases and 4,543,321 participants, were included for meta-analysis. Pooled results by using random-effects models suggested that maternal RA was associated with an increased risk for ASDs [odds ratio (OR) 1.39, 95% confidence interval (CI) 1.16-1.67], while maternal SLE was associated with an increased risk for ASDs only in western population (OR 1.91, 95% CI 1.02-3.57). Further study is warranted to confirm these results. En ligne : http://dx.doi.org/10.1007/s10803-020-04400-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=428 [article] Maternal Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Risk for Autism Spectrum Disorders in Offspring: A Meta-analysis [Texte imprimé et/ou numérique] / Zhixian ZHU, Auteur ; Shiming TANG, Auteur ; Xiaopeng DENG, Auteur ; Ying WANG, Auteur . - p.2852-2859. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-8 (August 2020) . - p.2852-2859 Mots-clés : Autism  Meta-analysis  Rheumatoid arthritis  Systemic lupus erythematosus Index. décimale : PER Périodiques Résumé : This study assessed the relationships between maternal systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA) and risk for autism spectrum disorders (ASDs) in offspring. Seven observational studies, including 25,005 ASD cases and 4,543,321 participants, were included for meta-analysis. Pooled results by using random-effects models suggested that maternal RA was associated with an increased risk for ASDs [odds ratio (OR) 1.39, 95% confidence interval (CI) 1.16-1.67], while maternal SLE was associated with an increased risk for ASDs only in western population (OR 1.91, 95% CI 1.02-3.57). Further study is warranted to confirm these results. En ligne : http://dx.doi.org/10.1007/s10803-020-04400-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=428

Systematic review and meta-analysis: multimodal functional and anatomical neural alterations in autism spectrum disorder / Zixuan GUO in Molecular Autism, 15 (2024)  

Public ISBD [article]  inMolecular Autism > 15 (2024) . - 16p. Titre : Systematic review and meta-analysis: multimodal functional and anatomical neural alterations in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Zixuan GUO, Auteur ; Xinyue TANG, Auteur ; Shu XIAO, Auteur ; Hong YAN, Auteur ; Shilin SUN, Auteur ; Zibin YANG, Auteur ; Li HUANG, Auteur ; Zhuoming CHEN, Auteur ; Ying WANG, Auteur Article en page(s) : 16p. Langues : Anglais (eng) Mots-clés : Humans  Autism Spectrum Disorder/diagnostic imaging  Brain/diagnostic imaging  Cerebral Cortex/diagnostic imaging  Gray Matter/diagnostic imaging  Gyrus Cinguli  Magnetic Resonance Imaging/methods  Autism spectrum disorder  Gray matter volume  Meta-analysis  Resting-state functional imaging  Voxel-based morphometry Index. décimale : PER Périodiques Résumé : BACKGROUND: This meta-analysis aimed to explore the most robust findings across numerous existing resting-state functional imaging and voxel-based morphometry (VBM) studies on the functional and structural brain alterations in individuals with autism spectrum disorder (ASD). METHODS: A whole-brain voxel-wise meta-analysis was conducted to compare the differences in the intrinsic functional activity and gray matter volume (GMV) between individuals with ASD and typically developing individuals (TDs) using Seed-based d Mapping software. RESULTS: A total of 23 functional imaging studies (786 ASD, 710 TDs) and 52 VBM studies (1728 ASD, 1747 TDs) were included. Compared with TDs, individuals with ASD displayed resting-state functional decreases in the left insula (extending to left superior temporal gyrus [STG]), bilateral anterior cingulate cortex/medial prefrontal cortex (ACC/mPFC), left angular gyrus and right inferior temporal gyrus, as well as increases in the right supplementary motor area and precuneus. For VBM meta-analysis, individuals with ASD displayed decreased GMV in the ACC/mPFC and left cerebellum, and increased GMV in the left middle temporal gyrus (extending to the left insula and STG), bilateral olfactory cortex, and right precentral gyrus. Further, individuals with ASD displayed decreased resting-state functional activity and increased GMV in the left insula after overlapping the functional and structural differences. CONCLUSIONS: The present multimodal meta-analysis demonstrated that ASD exhibited similar alterations in both function and structure of the insula and ACC/mPFC, and functional or structural alterations in the default mode network (DMN), primary motor and sensory regions. These findings contribute to further understanding of the pathophysiology of ASD. En ligne : https://dx.doi.org/10.1186/s13229-024-00593-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538 [article] Systematic review and meta-analysis: multimodal functional and anatomical neural alterations in autism spectrum disorder [Texte imprimé et/ou numérique] / Zixuan GUO, Auteur ; Xinyue TANG, Auteur ; Shu XIAO, Auteur ; Hong YAN, Auteur ; Shilin SUN, Auteur ; Zibin YANG, Auteur ; Li HUANG, Auteur ; Zhuoming CHEN, Auteur ; Ying WANG, Auteur . - 16p. Langues : Anglais (eng) in Molecular Autism > 15 (2024) . - 16p. Mots-clés : Humans  Autism Spectrum Disorder/diagnostic imaging  Brain/diagnostic imaging  Cerebral Cortex/diagnostic imaging  Gray Matter/diagnostic imaging  Gyrus Cinguli  Magnetic Resonance Imaging/methods  Autism spectrum disorder  Gray matter volume  Meta-analysis  Resting-state functional imaging  Voxel-based morphometry Index. décimale : PER Périodiques Résumé : BACKGROUND: This meta-analysis aimed to explore the most robust findings across numerous existing resting-state functional imaging and voxel-based morphometry (VBM) studies on the functional and structural brain alterations in individuals with autism spectrum disorder (ASD). METHODS: A whole-brain voxel-wise meta-analysis was conducted to compare the differences in the intrinsic functional activity and gray matter volume (GMV) between individuals with ASD and typically developing individuals (TDs) using Seed-based d Mapping software. RESULTS: A total of 23 functional imaging studies (786 ASD, 710 TDs) and 52 VBM studies (1728 ASD, 1747 TDs) were included. Compared with TDs, individuals with ASD displayed resting-state functional decreases in the left insula (extending to left superior temporal gyrus [STG]), bilateral anterior cingulate cortex/medial prefrontal cortex (ACC/mPFC), left angular gyrus and right inferior temporal gyrus, as well as increases in the right supplementary motor area and precuneus. For VBM meta-analysis, individuals with ASD displayed decreased GMV in the ACC/mPFC and left cerebellum, and increased GMV in the left middle temporal gyrus (extending to the left insula and STG), bilateral olfactory cortex, and right precentral gyrus. Further, individuals with ASD displayed decreased resting-state functional activity and increased GMV in the left insula after overlapping the functional and structural differences. CONCLUSIONS: The present multimodal meta-analysis demonstrated that ASD exhibited similar alterations in both function and structure of the insula and ACC/mPFC, and functional or structural alterations in the default mode network (DMN), primary motor and sensory regions. These findings contribute to further understanding of the pathophysiology of ASD. En ligne : https://dx.doi.org/10.1186/s13229-024-00593-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538

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