[article]
| Titre : |
Light-Adapted Electroretinogram Differences in Autism Spectrum Disorder |
| Type de document : |
texte imprimé |
| Auteurs : |
Paul A. CONSTABLE, Auteur ; Edward R. RITVO, Auteur ; Ariella R. RITVO, Auteur ; Irene O. LEE, Auteur ; Morgan L. MCNAIR, Auteur ; Dylan STAHL, Auteur ; Jane SOWDEN, Auteur ; Stephen QUINN, Auteur ; David H. SKUSE, Auteur ; Dorothy A. THOMPSON, Auteur ; James C. MCPARTLAND, Auteur |
| Article en page(s) : |
p.2874-2885 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Autism spectrum disorder Electroretinogram b-wave |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Light-adapted (LA) electroretinograms (ERGs) from 90 individuals with autism spectrum disorder (ASD), mean age (13.0 ± 4.2), were compared to 87 control subjects, mean age (13.8 ± 4.8). LA-ERGs were produced by a random series of nine different Troland based, full-field flash strengths and the ISCEV standard flash at 2/s on a 30 cd m(-2) white background. A random effects mixed model analysis showed the ASD group had smaller b- and a-wave amplitudes at high flash strengths (p < .001) and slower b-wave peak times (p < .001). Photopic hill models showed the peaks of the component Gaussian (p = .035) and logistic functions (p = .014) differed significantly between groups. Retinal neurophysiology assessed by LA-ERG provides insight into neural development in ASD. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-020-04396-5 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=428 |
in Journal of Autism and Developmental Disorders > 50-8 (August 2020) . - p.2874-2885
[article] Light-Adapted Electroretinogram Differences in Autism Spectrum Disorder [texte imprimé] / Paul A. CONSTABLE, Auteur ; Edward R. RITVO, Auteur ; Ariella R. RITVO, Auteur ; Irene O. LEE, Auteur ; Morgan L. MCNAIR, Auteur ; Dylan STAHL, Auteur ; Jane SOWDEN, Auteur ; Stephen QUINN, Auteur ; David H. SKUSE, Auteur ; Dorothy A. THOMPSON, Auteur ; James C. MCPARTLAND, Auteur . - p.2874-2885. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 50-8 (August 2020) . - p.2874-2885
| Mots-clés : |
Autism spectrum disorder Electroretinogram b-wave |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Light-adapted (LA) electroretinograms (ERGs) from 90 individuals with autism spectrum disorder (ASD), mean age (13.0 ± 4.2), were compared to 87 control subjects, mean age (13.8 ± 4.8). LA-ERGs were produced by a random series of nine different Troland based, full-field flash strengths and the ISCEV standard flash at 2/s on a 30 cd m(-2) white background. A random effects mixed model analysis showed the ASD group had smaller b- and a-wave amplitudes at high flash strengths (p < .001) and slower b-wave peak times (p < .001). Photopic hill models showed the peaks of the component Gaussian (p = .035) and logistic functions (p = .014) differed significantly between groups. Retinal neurophysiology assessed by LA-ERG provides insight into neural development in ASD. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-020-04396-5 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=428 |
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