An Investigation of Age-related Neuropathophysiology in Autism Spectrum Disorder Using Fixel-based Analysis of Corpus Callosum White Matter Micro- and Macrostructure / Melissa KIRKOVSKI in Journal of Autism and Developmental Disorders, 54-6 (June 2024)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 54-6 (June 2024) . - p.2198-2210 Titre : An Investigation of Age-related Neuropathophysiology in Autism Spectrum Disorder Using Fixel-based Analysis of Corpus Callosum White Matter Micro- and Macrostructure Type de document : Texte imprimé et/ou numérique Auteurs : Melissa KIRKOVSKI, Auteur ; Mervyn SINGH, Auteur ; Thijs DHOLLANDER, Auteur ; Ian FUELSCHER, Auteur ; Christian HYDE, Auteur ; Natalia ALBEIN-URIOS, Auteur ; Peter H. DONALDSON, Auteur ; Peter G. ENTICOTT, Auteur Article en page(s) : p.2198-2210 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Fixel-based analysis was used to probe age-related changes in white matter micro- and macrostructure of the corpus callosum between participants with (N = 54) and without (N = 50) autism spectrum disorder (ASD). Data were obtained from the Autism Brain Imaging Data Exchange-II (ABIDE-II). Compared to age-matched controls, young adolescents with ASD (11.19?+?7.54 years) showed reduced macroscopic fiber cross-section (logFC) and combined fiber-density and cross-section (FDC). Reduced fiber-density (FD) and FDC was noted in a marginally older (13.87?+?3.15 years) ASD cohort. Among the oldest ASD cohort (17.07?+?3.56 years), a non-significant trend indicative of reduced FD was noted. White matter aberration appears greatest and most widespread among younger ASD cohorts. This supports the suggestion that some early neuropathophysiological indicators in ASD may dissipate with age. En ligne : https://doi.org/10.1007/s10803-023-05980-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=530 [article] An Investigation of Age-related Neuropathophysiology in Autism Spectrum Disorder Using Fixel-based Analysis of Corpus Callosum White Matter Micro- and Macrostructure [Texte imprimé et/ou numérique] / Melissa KIRKOVSKI, Auteur ; Mervyn SINGH, Auteur ; Thijs DHOLLANDER, Auteur ; Ian FUELSCHER, Auteur ; Christian HYDE, Auteur ; Natalia ALBEIN-URIOS, Auteur ; Peter H. DONALDSON, Auteur ; Peter G. ENTICOTT, Auteur . - p.2198-2210. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 54-6 (June 2024) . - p.2198-2210 Index. décimale : PER Périodiques Résumé : Fixel-based analysis was used to probe age-related changes in white matter micro- and macrostructure of the corpus callosum between participants with (N = 54) and without (N = 50) autism spectrum disorder (ASD). Data were obtained from the Autism Brain Imaging Data Exchange-II (ABIDE-II). Compared to age-matched controls, young adolescents with ASD (11.19?+?7.54 years) showed reduced macroscopic fiber cross-section (logFC) and combined fiber-density and cross-section (FDC). Reduced fiber-density (FD) and FDC was noted in a marginally older (13.87?+?3.15 years) ASD cohort. Among the oldest ASD cohort (17.07?+?3.56 years), a non-significant trend indicative of reduced FD was noted. White matter aberration appears greatest and most widespread among younger ASD cohorts. This supports the suggestion that some early neuropathophysiological indicators in ASD may dissipate with age. En ligne : https://doi.org/10.1007/s10803-023-05980-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=530

Can Participation in a Community Organized Football Program Improve Social, Behavioural Functioning and Communication in Children with Autism Spectrum Disorder? A Pilot Study / Katherine HOWELLS in Journal of Autism and Developmental Disorders, 50-10 (October 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-10 (October 2020) . - p.3714-3727 Titre : Can Participation in a Community Organized Football Program Improve Social, Behavioural Functioning and Communication in Children with Autism Spectrum Disorder? A Pilot Study Type de document : Texte imprimé et/ou numérique Auteurs : Katherine HOWELLS, Auteur ; Carmel SIVARATNAM, Auteur ; Ebony LINDOR, Auteur ; Christian HYDE, Auteur ; Jane MCGILLIVRAY, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Nicole J. RINEHART, Auteur Article en page(s) : p.3714-3727 Langues : Anglais (eng) Mots-clés : Asd  Externalizing  Football  Internalizing  Organized physical activity  Social functioning Index. décimale : PER Périodiques Résumé : This pilot research investigated the effects of a community-based organized football program on behavioral, social and communicative outcomes in children with Autism Spectrum Disorder. In a non-randomized design, 19 children completed the football program and were compared pre- and post-intervention with 21 children who received no comparable intervention (ages 5-12 years). Caregiver-report using the child behavior checklist indicated a significant decrease in total, internalizing, DSM-oriented anxiety and social problems for children who participated in the program, with no change in the comparison group. There were no group differences in socialization and communication scores on the Vineland Adaptive Behavior scale. Results provide preliminary evidence in support of the program, justifying the need for further, more rigorous trials in this area. En ligne : http://dx.doi.org/10.1007/s10803-020-04423-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432 [article] Can Participation in a Community Organized Football Program Improve Social, Behavioural Functioning and Communication in Children with Autism Spectrum Disorder? A Pilot Study [Texte imprimé et/ou numérique] / Katherine HOWELLS, Auteur ; Carmel SIVARATNAM, Auteur ; Ebony LINDOR, Auteur ; Christian HYDE, Auteur ; Jane MCGILLIVRAY, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Nicole J. RINEHART, Auteur . - p.3714-3727. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-10 (October 2020) . - p.3714-3727 Mots-clés : Asd  Externalizing  Football  Internalizing  Organized physical activity  Social functioning Index. décimale : PER Périodiques Résumé : This pilot research investigated the effects of a community-based organized football program on behavioral, social and communicative outcomes in children with Autism Spectrum Disorder. In a non-randomized design, 19 children completed the football program and were compared pre- and post-intervention with 21 children who received no comparable intervention (ages 5-12 years). Caregiver-report using the child behavior checklist indicated a significant decrease in total, internalizing, DSM-oriented anxiety and social problems for children who participated in the program, with no change in the comparison group. There were no group differences in socialization and communication scores on the Vineland Adaptive Behavior scale. Results provide preliminary evidence in support of the program, justifying the need for further, more rigorous trials in this area. En ligne : http://dx.doi.org/10.1007/s10803-020-04423-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432

Hammering that Nail: Varied Praxis Motor Skills in Younger Autistic Children / Joel CRUCITTI in Journal of Autism and Developmental Disorders, 50-9 (September 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-9 (September 2020) . - p.3253-3262 Titre : Hammering that Nail: Varied Praxis Motor Skills in Younger Autistic Children Type de document : Texte imprimé et/ou numérique Auteurs : Joel CRUCITTI, Auteur ; Christian HYDE, Auteur ; Mark A. STOKES, Auteur Article en page(s) : p.3253-3262 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Children  Praxis  Specialist autistic school Index. décimale : PER Périodiques Résumé : Previous studies measuring praxis abilities in young autistic children have only used praxis measures that were not optimised for autistic individuals. Hence, we used the FAB-R to measure praxis skills in autistic (n?=?38) and typically developing (TD) children (n?=?38) aged between four and 10 years. Praxis abilities were generally not different between autistic and TD children. However, total dyspraxia and errors during verbal command and tool use were impaired in autistic children from a specialist autistic school (SAS). In contrast, autistic participants from the GC typically did not differ in praxis performance compared to controls. Hence, praxis abilities significantly vary between autistic younger children. Exploring mediating influences of such variability is imperative. En ligne : http://dx.doi.org/10.1007/s10803-019-04136-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430 [article] Hammering that Nail: Varied Praxis Motor Skills in Younger Autistic Children [Texte imprimé et/ou numérique] / Joel CRUCITTI, Auteur ; Christian HYDE, Auteur ; Mark A. STOKES, Auteur . - p.3253-3262. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-9 (September 2020) . - p.3253-3262 Mots-clés : Autism spectrum disorder  Children  Praxis  Specialist autistic school Index. décimale : PER Périodiques Résumé : Previous studies measuring praxis abilities in young autistic children have only used praxis measures that were not optimised for autistic individuals. Hence, we used the FAB-R to measure praxis skills in autistic (n?=?38) and typically developing (TD) children (n?=?38) aged between four and 10 years. Praxis abilities were generally not different between autistic and TD children. However, total dyspraxia and errors during verbal command and tool use were impaired in autistic children from a specialist autistic school (SAS). In contrast, autistic participants from the GC typically did not differ in praxis performance compared to controls. Hence, praxis abilities significantly vary between autistic younger children. Exploring mediating influences of such variability is imperative. En ligne : http://dx.doi.org/10.1007/s10803-019-04136-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430

Head circumference trends in autism between 0 and 100 months / Joel CRUCITTI in Autism, 24-7 (October 2020)  

Public ISBD [article]  inAutism > 24-7 (October 2020) . - p.1726-1739 Titre : Head circumference trends in autism between 0 and 100 months Type de document : Texte imprimé et/ou numérique Auteurs : Joel CRUCITTI, Auteur ; Christian HYDE, Auteur ; Peter G. ENTICOTT, Auteur ; Mark A. STOKES, Auteur Article en page(s) : p.1726-1739 Langues : Anglais (eng) Mots-clés : *age  *autism  *head circumference  *sex Index. décimale : PER Périodiques Résumé : Summaries of studies that have measured head size in those with autism, known as meta-analyses, currently exist. However, this approach does not adequately explain extreme cases (such as those with extremely small, or extremely large, head size). Because of this, we obtained all available published data measuring head size (12 studies). The data from each study were then combined to make a larger dataset. We found that females with autism aged 12-17?months had, on average, smaller head sizes. Otherwise, average head size was not atypical in autism. However, we found that males with autism were more likely to have extreme head sizes at birth and between 60 and 100?months, a small head between 6 and 11?months, and a large head between 12 and 17?months. Females with autism were more likely to have extreme head sizes between 36 and 59?months and were less likely at birth. Our approach was able to measure the influence of age and biological sex on head size in autism, as well as the frequency of extreme cases of head size in autism. These results add to what we already know about head size in autism. En ligne : http://dx.doi.org/10.1177/1362361320921037 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=431 [article] Head circumference trends in autism between 0 and 100 months [Texte imprimé et/ou numérique] / Joel CRUCITTI, Auteur ; Christian HYDE, Auteur ; Peter G. ENTICOTT, Auteur ; Mark A. STOKES, Auteur . - p.1726-1739. Langues : Anglais (eng) in Autism > 24-7 (October 2020) . - p.1726-1739 Mots-clés : *age  *autism  *head circumference  *sex Index. décimale : PER Périodiques Résumé : Summaries of studies that have measured head size in those with autism, known as meta-analyses, currently exist. However, this approach does not adequately explain extreme cases (such as those with extremely small, or extremely large, head size). Because of this, we obtained all available published data measuring head size (12 studies). The data from each study were then combined to make a larger dataset. We found that females with autism aged 12-17?months had, on average, smaller head sizes. Otherwise, average head size was not atypical in autism. However, we found that males with autism were more likely to have extreme head sizes at birth and between 60 and 100?months, a small head between 6 and 11?months, and a large head between 12 and 17?months. Females with autism were more likely to have extreme head sizes between 36 and 59?months and were less likely at birth. Our approach was able to measure the influence of age and biological sex on head size in autism, as well as the frequency of extreme cases of head size in autism. These results add to what we already know about head size in autism. En ligne : http://dx.doi.org/10.1177/1362361320921037 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=431

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